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Sommaires des Revues - Word Neurosurgery

World Neurosurgery

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Ganglioglioma progression to combined anaplastic ganglioglioma and anaplastic pleomorphic xanthoastrocytoma. Case report and literature review  Voir?

Composite ganglioma and pleomorphic xanthoastrocytoma with anaplastic features in both components is an extremely rare glioneuronal tumor. 5 cases of anaplastic progression in the glioma component have been reported. These tumors generally affect young patients who suffer brain tumor-related epilepsy, are usually located in the temporal lobe or in the cerebellum, and may associate leptomeningeal spreading. Its current optimal treatment consists of maximal safe surgical resection and adjuvant chemoradiotherapy.

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Lumbar spine infection by Granulicatella and Abiotrophia species: A case report  Voir?

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Minimally Invasive Separation Surgery with Intraoperative Stereotactic Guidance: A Feasibility Study  Voir?

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Incremental value of multiparametric whole-body MR imaging over whole spine magnetic resonance imaging in Neurofibromatosis type I patients  Voir?

A substantially larger peripheral nerve sheath tumor burden is detected on WBMRI as compared to WSMRI in NF1 patients.
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Comparation of two operative methods for treating laterocollis and torticollis subtypes of spasmodic torticollis. Follow up of 121 cases  Voir?

The aim of this study was to compare the effects and complications of microvascular decompression(MVD) and neurectomy of spinal accessory nerve in the treatment of laterocollis and torticollis subtypes spasmodic torticollis (ST).
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Usefulness of reintervention in recurrent glioblastoma: an indispensable weapon for increasing survival  Voir?

Glioblastoma is the most frequent primary brain tumour and despite of complete treatment survival is still poor. The aim of this study is to define the utility of reoperation for improving survival in patients with recurrent glioblastoma, and determine other prognostic factors associated with longer survival.

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Falxuplication, A Novel Method for Wrap-Clipping a Fusiform Aneurysm: A Technical Note  Voir?

Various techniques have been used for wrap-clipping a ruptured, fusiform intracranial aneurysm. However, there is no available literature on use of the falx cerebri for wrap-clipping.
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Long-term patency of posterior auricular artery–middle cerebral artery bypass for adult-onset moyamoya disease: case report and review of literature  Voir?

Direct extracranial-intracranial (EC–IC) bypass is one of the fundamental techniques to prevent recurrent stroke in patients with adult-onset ischemic moyamoya disease. When the standard superficial temporal artery (STA) cannot be used for a graft, the posterior auricular artery (PAA) can be a potential surrogate graft.

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Chronic Subdural Hematoma: a Historical and Clinical Perspective  Voir?

Chronic subdural hematoma (cSDH) affects 1-5.3 per 100,000 individuals annually, with the incidence expected to rise as the U.S. population ages. The symptoms of cSDH are often nonspecific, with headaches being the most common complaint. Other symptoms include weakness, balance and gait problems, and memory problems. A variety of clinical factors must be taken into account in the treatment of cSDH, and the multifaceted treatment paradigms continue to evolve. This review aims to highlight the clinical complexity of cSDH, while presenting a brief historical discussion of cSDH.

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Chronic Subdural Hematoma: a Perspective on Subdural Membranes and Dementia  Voir?

Chronic subdural hematoma (cSDH) is a common intracranial pathology, and a leading cause of reversible dementia. cSDH is projected to affect at least 60,000 new individuals in the United States annually by 2030.This can result from mild to moderate head trauma that leads to hemorrhaging in the dura-arachnoid interface. The short and long-term effects of cSDH and the subdural membrane on the pathogenesis of dementia and the newly discovered dural lymphatics is a topic of increasing importance. This manuscript aims to review the complex pathogenesis of the subdural membrane, and the link between head trauma, dementia, and dural lymphatics.

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Fluorescein-guided resection of intramedullary spinal cord tumors: results from a preliminary, multicentric, retrospective study  Voir?

IMSCTs are rare heterogenous lesions usually enhancing at pre-operative MRI, due to a damaged BBB. SF is a dye that accumulates in areas of the CNS with a damaged BBB. Given the pattern of MRI contrast-enhancement of the majority of IMSCTs, the use of this fluorescent tracer could improve tumor visualization and quality of resection. In this paper, we present the first experience on the application of fluorescein-guided technique for surgical removal of IMSCTs.

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Mini-pterional and supraorbital keyhole craniotomies for ruptured anterior circulation aneurysms: Experience at a single center  Voir?

A keyhole craniotomy is a type of pterional craniotomy that involves a minimally invasive approach for the treatment of cerebral aneurysms. Currently, the mini-pterional keyhole craniotomy (MPKC) and supraorbital keyhole craniotomy (SOKC) procedures are frequently performed. We evaluated the feasibility and safety of SOKCs and MPKCs for the clipping of ruptured intracranial aneurysms in the anterior cerebral circulation as an alternative to the pterional approach in a consecutive series of 25 patients.

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Results of conservative follow-up or surgical treatment of mayamoya patients who present without hemorrhage, TIA, or stroke  Voir?

The epidemiology of asymptomatic Moyamoya disease (MMD) is still unclear, and the best management remains controversial. The aim of this study is to evaluate the prognosis of these patients with different management, conservative follow-up or surgical treatment.
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Stereotactic Radiosurgery for Type 1 versus Type 2 Trigeminal Neuralgias  Voir?

It remains unclear whether if stereotactic radiosurgery (SRS) offers the same benefit for patients with type 2 trigeminal neuralgia (TN2) as for those with type 1 trigeminal neuralgia (TN1). The objective of this study is to compare the outcomes of patients with TN1 and TN2 following SRS.
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Characteristics of blood blister-like aneurysms with a saccular-shape appearance  Voir?

Blood blister-like aneurysms (BBAs) are a subgroup of aneurysms located on non-branching sites of the internal carotid artery (ICA) and characterized by small size, a fragile wall, and a poorly defined broad-based neck. Both direct surgery and endovascular treatment for BBA are often challenging. Some of them were reported to look like a true saccular aneurysm, and the misdiagnosis of BBA might result in catastrophic outcomes. The purpose of this study is to clarify the clinical and intraoperative findings of saccular BBAs.

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Hearing outcome following microvascular decompression for hemifacial spasm: series of 1434 cases  Voir?

Although hearing impairment after microvasuclar decompression (MVD) for hemifacial spasm (HFS) is not common, its occurrence could detrimentally affect the patient`s surgical outcome. The object of this study is to address the optimal approaches for reducing postoperative hearing problems after MVD for HFS.

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Impact of Active Leisure (Non-Competitive) Contact Sports Activities on Space Available for Cord (SAC) of Sub-Axial Cervical Spine of Asymptomatic Adults  Voir?

Leisure sports activities are assumed to be safe. It is however possible that participation in contact sports as leisure activity may also affect the SAC.
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Steinmann Pins for C1 Lateral Mass Screw Placement During Atlantoaxial Stabilization  Voir?

The authors describe a modified technique for placement of the C1 lateral mass screw using a Steinmann pin as a guide. This technique minimizes dissection and provides atlantoaxial stabilization during arthrodesis.
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C1-C2 pedicle screw fixation for atlantoaxial dislocation in pediatric patients younger than 5 years: A case series of 15 patients  Voir?

C1-C2 pedicle screw fixation has become popular for providing excellent bony purchase and avoiding neurovascular complications. However, it may be technically challenging in children. The objective of this study is to investigate the safety and efficacy of C1-C2 pedicle screw fixation for atlantoaxial dislocation (AAD) in pediatric patients younger than 5 years, and to evaluate the preliminary clinical and radiographic results.

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The safety of Irreversible Electroporation on Nerves Adjacent to Treated Tumors  Voir?

To evaluate the safety of irreversible electroporation (IRE) on the sciatic nerve after IRE ablation of adjacent tumor.
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Monolateral pterional keyhole approaches to bilateral cerebral aneurysms: Anatomy and clinical application  Voir?

To study the anatomy and clinical application of monolateral pterional keyhole approach for treating bilateral cerebral aneurysms.
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Association of ACVRL1 genetic polymorphisms with arteriovenous malformations: A case-control study and meta-analysis  Voir?

To investigate the association between polymorphisms in the gene encoding activin receptor-like kinase 1 (ACVRL1) with brain arteriovenous malformations (BAVMs) using a case-control study in a Chinese Han population, followed by a meta-analysis of the published literature.
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Results of combined intraventricular neuroendoscopic procedures in 130 cases with special focus on fornix contusions  Voir?

The growing experience with intraventricular neuroendoscopic procedures showed good results in the combination of ETV and tumor biopsy. Other possible combinations are mainly presented in subgroups in the literature. Here, the authors present their experience with combined intraventricular procedures within one setting over the last two decades.

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Photoacoustic Imaging for Maximizing Glioma Resection  Voir?

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Reading Between the Joints—Using Spinal Magnetic Resonance Imaging for Evaluation of Instability  Voir?

Magnetic resonance imaging (MRI) is one of the most common investigations ordered for the evaluation of back and leg pain. Usually, supine MRI is one of the initial tests for the screening of degenerative spine diseases and lumbar spinal stenosis. It is useful for assessing disease severity, involvement of the spine and its surrounding structures, and making decisions about surgery. With all of these advantages in hand, the role of MRI is considered limited in a few aspects—one is the determination of instability.

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Staged stenting with or without additional coils after conventional initial coiling of acute ruptured wide-neck intracranial aneurysms  Voir?

Stent-assisted coiling technique has been more and more adopted in the treatment of intracranial aneurysms, and has been shown to improve long-term angiographic results, however, the treatment is relatively contraindicated in acutely ruptured aneurysms for its ischemic and hemorrhagic complications. Staged stenting after conventional coiling has emerged as a potential treatment strategy for ruptured wide-neck aneurysms. This study assessed the safety and efficacy of coiling in the acute phase followed by delayed stenting for ruptured wide-neck intracranial aneurysms.

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Minimally invasive versus open surgery for lumbar synovial cysts  Voir?

Lumbar synovial cysts are relatively infrequent. Historically, these benign lesions have been treated with open excision, sometimes associated with fusion.The aim of this study is to compare Minimally Invasive Surgery (MIS) with Open Surgery (OS) for the treatment of lumbar synovial cysts.
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Flexible ultrathin endoscope integrated with irrigation suction apparatus for assisting microneurosurgery  Voir?

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Implications of Anti-Angiogenic Therapy on Radiographic Assessment of Brain Tumours  Voir?

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Predicting short-term outcome after surgery for primary spinal tumors based on patient frailty  Voir?

The concept of ‘Frailty,’ i.e. decreased physiologic reserve and increased vulnerability to stressors beyond what is expected for normal aging is associated with increased risk of morbidity and mortality. The objective of this study was to develop a preoperative frailty index (STFI) for patients undergoing surgery for primary spinal column tumors that predicts morbidity, mortality, and length of stay.

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Treatment of large or giant cavernous aneurysm associated with a persistent trigeminal artery: a case report and review of literature  Voir?

Primitive trigeminal artery (PTA) is the most common anomaly of primitive carotid-basilar anastomosis and is associated with cerebrovascular anomalies, such as aneurysm. Large or giant cavernous aneurysm associated with PTA is rare, and the treatment strategies differ in comparison to large or giant aneurysm without PTA. In this article, we report an unusual case of a giant cavernous aneurysm associated with PTA and review treatment strategies for large or giant cavernous aneurysm associated with PTA.

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Operative Management of Distal Anterior Cerebral Artery Aneurysms Through a Mini Anterior Interhemispheric Approach  Voir?

Distal anterior cerebral artery (DACA) aneurysms, also referred to as pericallosal artery aneurysms, are present in 1.5 to 9% of all intracranial aneurysms. This study aims to describe the importance of the microsurgical anatomy of the DACA and demonstrate the surgical nuances for handling DACA aneurysms, with a minimally invasive surgical technique

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Intraoperative visualization of a spinal arachnoid cyst by using pyoktanin blue: technical note  Voir?

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Initial Clinical Experience with AView—A Clinical Computational Platform for Intracranial Aneurysm Morphology, Hemodynamics, and Treatment Management  Voir?

Intracranial aneurysm (IA) management is challenging. Clinicians often rely on varied and intuitively disparate ways of evaluating rupture risk that may only partially take into account complex hemodynamic and morphologic factors. We developed a prototype of a clinically-oriented, streamlined, computational platform, AView, for rapid assessment of hemodynamics and morphometrics in clinical settings. To show the potential clinical utility of AView, we report our initial multicenter experience highlighting the possible advantages of morphologic and hemodynamic analysis of IAs.

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Spontaneous Hemorrhagic Glioblastoma revealed by Arterial Spin Labeling  Voir?

We report a case of a haemorrhagic tumor early detected by pseudo-continuous arterial spin labeling sequence (pCASL) in the case where conventional MRI sequences where not contributive.
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The Influence of Parkinson’s Disease on Lumbar Decompression Surgery:A Retrospective Case Control Study  Voir?

Parkinson’s disease (PD) is a major risk factor during spine surgery, and its frequency is rising as the population ages. The study aim was to examine the influence of PD specifically on lumbar decompression surgery.
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Robotic Stereotactic Assistance (ROSA) utilization for minimally invasive placement of intraparenchymal hematoma and intraventricular catheters: Case report  Voir?

In patients with supratentorial spontaneous intracerebral hemorrhage, intrahematomal catheter placement may allow for intra-clot thrombolysis and drainage. Robotic assistance may be used for the stereotactic placement of catheters.
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Distally enlarged feeding artery phenomenon in Intracranial Dural Arteriovenous Fistula: Alternative Access Route to Transarterial Intravenous Embolization Dong  Voir?

Transvenous (TV) embolization is ideal for endovascular treatment of intracranial dural arteriovenous fistulas (DAVF). However, it is not always feasible because of various factors, and transarterial (TA) embolization could then be tried. We aimed to determine the incidence of ‘distally enlarged feeding artery phenomenon’ and the major feeding artery in DAVF. In case TV approach is difficult and this phenomenon observed, we could use this vessel for transarterial intravenous (TAIV) embolization as an endovascular treatment modality for DAVF.

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Accuracy of Pedicle Screw Insertion among Three Image-Guided Navigation Systems: A Systematic Review and Meta-Analysis  Voir?

Many retrospective studies of pedicle screw placement have revealed that intraoperative navigation systems provide higher accuracy rates and safety than do free-hand techniques. The accuracy of various image-guided navigation systems has been studied; however, differences have not been well defined due to the lack of adequate evidence-based comparative studies.

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Craniospinal germinomas in a patient with Down syndrome successfully treated with standard-dose chemotherapy and craniospinal irradiation: A case report and literature review  Voir?

Patients with Down syndrome (DS) are more likely to develop chemotherapy-related complications. The standard treatment for these patients with cancers has not yet been established, and the risks of standard chemotherapy are unclear. In this paper, a rare case of multiple craniospinal germinomas in a patient with DS, which was successfully treated with standard-dose chemotherapy combined with craniospinal irradiation is reported.

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A tortuous process of surgical treatment for a large calcified chronic subdural hematoma  Voir?

Calcified chronic subdural hematoma (CCSDH) is a rare disease.1-3 No standard approach for this disease were established. Reports covering both the burring hole trepanation and craniotomy for CCSDH was rare. Furthermore, the infection of CCSDH after the burr hole trepanation has not been reported in the literature.

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The accuracy of shape irregularity and density heterogeneity on non-contrast computed tomography for predicting hematoma expansion in spontaneous intracerebral hemorrhage: a systematic review and meta-analysis  Voir?

This systematic review and meta-analysis was aimed to evaluate the predictive values of shape irregularity and density heterogeneity of hematoma on non-contrast computed tomography (NCCT) for hematoma expansion (HE).
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Morbidity and Mortality of Meningioma Resection Increases in Octogenarians  Voir?

The incidence of meningioma has increased drastically recently, particularly in the elderly. Surgical intervention has the potential to reduce neurological symptoms and to achieve favorable, long-term outcomes. There is considerable variability in the literature examining the relationship between age and outcomes following meningioma surgery. The objective of this study was to identify the relationship between age and postoperative complications following craniotomy for resection of meningioma.

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Asymptomatic ischemic risks in microsurgical clipping for unruptured intracranial aneurysms in anterior circulation  Voir?

The ischemic risk in prophylactic treatments of unruptured intracranial aneurysms (UIAs) is a serious health concern.
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Stereoscopic 3D Neuroanatomy Lectures Enhance Neurosurgical Training: Prospective Comparison to Traditional Teaching  Voir?

Stereoscopic three-dimensional (3D) imaging is increasingly used in the teaching of neuroanatomy and although this is mainly aimed at undergraduate medical students, it has enormous potential for enhancing the training of neurosurgeons. This study aims to assess whether 3D lecturing is an effective method of enhancing the knowledge and confidence of neurosurgeons, and how it compares to traditional two-dimensional (2D) lecturing and cadaveric training.

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Early outcomes of endoscopic contralateral foraminal and lateral recess decompression via an interlaminar approach in patients with unilateral radiculopathy from unilateral foraminal stenosis  Voir?

Percutaneous endoscopic contralateral interlaminar lumbar foraminotomy (PECILF) for lumbar degenerative spinal stenosis is an established procedure. Better preservation of contralateral facet joint compared to that of the approach side has been demonstrated with uniportal bilateral decompression. The aim of this retrospective case series was to analyze the early clinical and radiological outcomes of standalone contralateral foraminotomy and lateral recess decompression using PECILF.

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Radiological Predictors for Extent of Resection in Pituitary Adenoma Surgery. A Single-center study  Voir?

Preoperative radiologic evaluation of pituitary adenomas is essential. Despite the efforts made to determine the achieved resection grade after pituitary adenoma surgery, there is a high level of disagreement among all the available classifications and measurement methods employed. Our study aimed to determine pituitary adenoma imaging features, easily obtained from preoperative magnetic resonance, which could be used as resection predictor variables. Secondly, we analyzed the usefulness of the ellipsoid method in pituitary adenoma volume determination.

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Successful treatment by microvascular decompression surgery of a patient with hemiparesis due to vertebral artery compression of the medulla oblongata: A case report and literature review  Voir?

Little literature is available on hemiparesis caused by vascular medullary compression, which may occur as a result of dolichoectasia of the vertebrobasilar arterial system. In this paper, we report a case of vertebral artery compression of the medulla oblongata in a 67-year old woman. The patient was hypertensive and developed hemiparesis and intermittent spasms for five years, which became worsened for one year. Cranial nerve MRI showed compression of the medulla oblongata by the left vertebral artery.

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Spinal Hydatid Cyst Disease  Voir?

A hydatic cyst (HC) is a zoonotic infection affecting the liver and lungs, with rare spinal involvement. We discuss the long-term results of 8 spinal HC patients who were monitored at our clinic for 7-15 years.
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Simple Lateral Suboccipital Approach and Modification for Vertebral Artery Aneurysms: A Study of 52 cases over 10 years  Voir?

Complex skull base approaches are frequently used to treat intracranial vertebral artery (VA) and proximal posterior inferior cerebellar artery (PICA) aneurysms. These complex procedures are associated with higher risk of neurovascular injury. Hence, a less invasive surgical approach is needed to improve treatment’s efficacy and safety.

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Hyponatremia in traumatic brain injury - a practical management protocol  Voir?

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Acquired Chiari I Malformation with Syringomyelia secondary to Colloid cyst with Hydrocephalus - Case report and review of literature  Voir?

Acquired Chiari malformation and associated syringomyelia have been previously described following lumbar puncture/drainage, lumboperitoneal shunts, and spontaneous CSF leakage. In addition to these etiologies, space-occupying lesions such as meningiomas, epidermoid cysts, medulloblastomas, and arachnoid cysts are rare causes of acquired Chiari malformation and syringomyelia. We report a rare case of colloid cyst with hydrocephalus causing secondary Chiari malformation with syringomyelia.

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A Pilot Study of the Level of Evidence and Collaboration in Published Neurosurgical Research  Voir?

Large-scale studies analyzing neurosurgical published research are lacking.
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Medullary decompression by sling repositioning of the Vertebral Artery with operative video: Technical Case Report  Voir?

Vascular compression of the medullary pyramid resulting in neurological compromise is rare, therefore, diagnosis is difficult and ultimately delayed. Most patients present with a combination of cranial nerve, autonomic, and/or motor and sensory dysfunction. Presentation with a single sign such as hemiparesis is rare. The low number of cases reported has made it impossible to define a standard treatment for this unusual disorder.

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Altered Expression of microRNA-15a and Kruppel-like Factor 4 in Cerebrospinal Fluid and Plasma after Aneurysmal Subarachnoid Hemorrhage  Voir?

Cerebral vasospasm (CVS) is a major determinant of prognosis in patients with subarachnoid hemorrhage (SAH). Alteration in the vascular phenotype contributes to development of CVS. However, little is known about the role of microRNAs (miRNAs) in the phenotypic alteration after SAH. We investigated the expression profile of miRNAs and the chronological changes in the expression of microRNA-15a (miR-15a) and Kruppel-like factor 4 (KLF4), a potent regulator of vascular phenotype modulation that modulates the expression of miR-15a, in the plasma and cerebrospinal fluid (CSF) of SAH patients.

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Incidence of postoperative hematomas requiring surgical treatment in neurosurgery: a retrospective observational study  Voir?

We aimed to characterize the occurrence of postoperative hematoma (POH) after neurosurgery overall and according to procedure type, and describe the prevalence of possible confounders.
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Cervical en-plaque extradural meningioma involving the brachial plexus: Case report  Voir?

Meningioma is one of the commonest spinal tumors, with a predilection for intradural occurrence. Its occurrence as an extradural, en-plaque variety is uncommon. We report an en-plaque extradural cervical meningioma with a diffuse involvement of the brachial plexus. The imaging features of this unusual behaviour of a spinal meningioma and the treatment options are discussed in the light of a brief literature review.

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Clinical Manifestations of Isolated Chronic Middle Cerebral Artery Occlusion in Relation to Angiographic Features  Voir?

Isolated chronic middle cerebral artery occlusion (ChMCAO) is not a rare condition, and it is known to cause hemodynamic stroke. The purpose of this study was to evaluate differences in the clinical manifestations and prognosis of isolated ChMCAO in relation to angiographic features.
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Current status of worldwide use of patient-reported outcome measures (PROMs) in spine care  Voir?

Patient-reported outcome measures PROMs are the most widely accepted means of measuring outcomes following spine procedures. We sought to determine the current status of worldwide use of PROMs in Latin America (LA), Europe (EU), Asia Pacific (AP), North America (NA), and Middle East (ME) in order to determine the barrier to its full implementation.

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Chronological Evaluation of Cerebral Hemodynamics by Dynamic Susceptibility Contrast Magnetic Resonance Imaging after Indirect Bypass Surgery for Moyamoya Disease  Voir?

Although indirect bypass surgery is an effective treatment option for patients with ischemic-onset moyamoya disease (MMD), the time point after surgery at which the patients’ hemodynamic status starts to improve and the time point at which the improvement reaches a maximum have not been known. The objective of present study is to evaluate the hemodynamic status time course after indirect bypass surgery for MMD, using dynamic susceptibility contrast-magnetic resonance imaging (DSC-MRI).

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Minimally Invasive treatment for a Sacral Tarlov Cyst through tubular retractors: Case report  Voir?

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Lumbosacral subdural hematoma following glioblastoma multiforme resection: possible radiographic evidence for the downward migration of intracranial blood  Voir?

Spinal subdural hematomas (SSDHs) are rare and usually associated with bleeding diatheses, trauma, iatrogenic injury, spinal vascular malformations, or intraspinal tumors. We report a case of a 75-year-old male who developed a symptomatic lumbosacral SSDH after undergoing resection of a right temporal glioblastoma multiforme. The patient subsequently recovered and was discharged home. Over the next two weeks he developed progressively worsening symptoms of lower back pain, lower extremity weakness, and urinary retention.

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Impact of Onyx® Embolization on Radiosurgical Management of Cerebral AVM: Treatment and Outcome  Voir?

Stereotactic radiosurgery (SRS) is a well-established treatment modality for cerebral arterio-venous malformations (AVMs). The main limiting factor in the radiosurgical treatment of AVMs is the volume of the nidus with high-grade lesions often requiring combined treatment to reduce the SRS target volume. To overcome this limitation, we have been using a combined treatment approach consisting of endovascular embolization with ONYX followed by SRS.

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A Secure Approach to the Inferior Horn using the Deep Medullary Vein as an Anatomical Guide: Technical Note  Voir?

Safe entry to the inferior horn is required for a selective approach into the medial temporal region. However, this sometimes could be challenging for inexperienced surgeons. Our objective is to verify the usefulness of the deep medullary vein as an intraoperative landmark for safely entering the inferior horn during the transsylvian selective approach into the mesial temporal region.

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Medical Training and the Brain death exam: A Single Institution’s Experience  Voir?

Clinicians may have limited opportunities to perform neurological determination of death (NDD; brain death) certification during their training. This study aims to evaluate the level of resident exposure to the brain death exam at a large volume donor hospital.
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Ethnicity, Race, and Post-Operative Stroke Risk among 53,593 Patients with Asymptomatic Carotid Stenosis Undergoing Revascularization  Voir?

The incidence of post-operative stroke following carotid endarterectomy is an uncommon event and differences by racial and ethnic subgroups are not fully described in the literature.
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Marginal en bloc resection of C2-3 chordoma with bilateral vertebral artery preservation and mesh cage reconstruction with review of previously published cases  Voir?

Chordomas arise from remnants of the notocord and occur throughout the neuroaxis. En bloc resection of chordomas can prove especially challenging in the upper cervical spine secondary to the unique structural anatomy and intimate relationship to the vertebral arteries and spinal cord.
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Cerebrospinal Fluid Leak Rhinorrhea after Systemic Erlotinib Chemotherapy for Metastatic Lung Cancer: A Familiar Problem from an Unfamiliar Culprit  Voir?

Cerebrospinal fluid (CSF) rhinorrhea after medical therapy for pituitary prolactinoma is a rare but well-described phenomenon. To our knowledge, no CSF leaks have been reported after targeted medical treatment of pituitary or anterior skull base metastases. We report this unusual case to raise awareness of spontaneous CSF leaks in the setting of skull base metastatic disease.

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Endoscopic Transsphenoidal Approach for Acromegaly: Remission Rates in 401 Patients: 2010 Consensus Criteria  Voir?

Transsphenoidal surgery is the first choice treatment for acromegaly. Postoperative remission is an important predictor of outcome. Various factors have been described as markers of remission preoperative mean growth hormone (GH) and insulin-like growth factor-1 levels, cavernous sinus invasion, tumor size, extra pseudocapsule resection, and experience of the surgeon.

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The occipital artery as an alternative donor for low-flow bypass to anterior circulation after ICA occlusion failure prior to exenteration for an atypical cavernous sinus meningioma: A technical case report  Voir?

and Importance: In skull-base tumors involving the cavernous sinus (CS), indications for aggressive resection are sparse and must be carefully examined because of their invasiveness. With careful evaluation, techniques including internal carotid artery (ICA) sacrifice with or without extracranial-intracranial (EC-IC) bypass may still be an option in some cases. In addition, previous surgery with the sacrifice of potential donor vessels requires adjusting the revascularization strategy. Here, we describe an OA-MCA bypass prior to the skull-base tumor resection.

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Quantitative comparison of three endoscopic approaches to the parasellar region: Laboratory investigation  Voir?

Endoscopic endonasal transsphenoidal and contralateral sublabial transmaxillary approaches are used for approaching parasellar lesions. The aim of this anatomical study was to compare endoscopic endonasal uninostril and binostril (contralateral) and contralateral sublabial transmaxillary approaches using a quantitative analysis of exposure limits and instrument working avenues.

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Anterior lumbar corpectomy with expandable titanium cage reconstruction - A case series of 42 patients.  Voir?

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Single-step resection of an intraosseous meningioma and cranial reconstruction: technical note  Voir?

Simultaneous tumour resection and cranial reconstruction can be a challenging task. Surgical navigation is an indispensible tool in making this single-step procedure possible. In this case report we describe a new technique for this procedure to ensure a precise resection and optimal fit of the implant in a patient with an intraosseous meningioma.

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Moyamoya vasculopathy in PHACE syndrome: six new cases and review of the literature  Voir?

PHACE syndrome is a neurocutaneous disorder including posterior fossa malformations, hemangiomas, arterial lesions, cardiac defects, and eye abnormalities. PHACE arteriopathies may be progressive and have been recently categorized based on the risk of acute ischemic stroke, raising attention to the potentially devastating consequences of cerebrovascular complications in this syndrome. On the other hand, the natural history of arteriopathy in PHACE syndrome remains poorly understood. At the moment, there are no established surgical guidelines for high risk vasculopathies, including quasi-moyamoya, in this syndrome.

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Comparison of unilateral and bilateral craniotomy for the treatment of bilateral middle cerebral artery aneurysms: anatomical and clinical parameters and surgical outcomes  Voir?

To compare two craniotomy approaches (unilateral and bilateral) in terms of anatomical and clinical parameters and surgical outcomes.
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Transsphenoidal surgery for mixed pituitary gangliocytoma-adenomas  Voir?

Most sellar gangliocytomas are discovered with a concurrent pituitary adenoma, also known as a mixed gangliocytoma-adenoma (MGA). MGAs are rare with less than 100 cases reported in the literature and only one previously documented surgical series. As MGAs are radiologically indistinguishable from pituitary adenomas, their diagnosis is often made following surgery. This, combined with the paucity of clinical outcome data for these tumors, makes their diagnosis and management challenging. Thus, the clinical presentation and outcomes of 10 individuals who were diagnosed with a MGA at a single institution are described.

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Why does the health-related quality of life in idiopathic normal pressure hydrocephalus fail to improve despite the favorable clinical outcome?  Voir?

Occasionally a favorable clinical disease-specific outcome does not reflect into improved generic health-related quality of life (HRQoL) in patients with idiopathic normal pressure hydrocephalus (iNPH) one year after the installation of the cerebrospinal fluid (CSF) shunt. Our aim was to identify factors causing this discrepancy.

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Sacral-Alar-Iliac Fixation in Children with Neuromuscular Scoliosis: Minimum 5-Year Follow-Up  Voir?

The aim of our study was to investigate the 5-year outcomes of children with neuromuscular scoliosis treated with sacral-alar-iliac screws.
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Corrigendum to ‘Jack Nicholson: A Reel and Real-Life Contribution to Neurosciences’ [World Neurosurgery 101 (2017) 718–721]  Voir?

The authors regret that the following Acknowledgement text was missing from the original published article: “We sincerely thank Dr. Kulbir Singh Walia (MD) from New Jersey for his valuable inputs. We also thank Miss Shtantika Mukherjee for language edits and Dr. Prashant K Prasad for his valuable inputs.”

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Motor Cortex Stimulation in Patients Suffering from Chronic Neuropathic Pain: Summary of an Expert Meeting and Pre-meeting Questionnaire, Combined with a Literature Review  Voir?

Motor Cortex Stimulation (MCS) was introduced in the early 1990’s by Tsubokawa and his group for patients diagnosed with drug-resistant, central neuropathic pain. Inconsistencies concerning the details of this therapy and its outcomes and poor methodology of most clinical essays, divide the neuromodulation society worldwide in “believers” and “non-believers”. A European expert meeting was organized in Brussels, Belgium by the Benelux Neuromodulation Society (BNS)in order to develop uniform MCS protocols in the pre-, intra- and post-operative course.

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Stereotactic Radiosurgery of Central Skull Base Meningioma’s – Volumetric Evaluation and Long-term Outcomes  Voir?

Central skull base meningioma’s (CSMs) complete resection is possible but it is often associated with high morbidity. Stereotactic radiosurgery (SRS) plays an appreciable role in the management of skull base meningiomas. The study aims to apply volumetric methods to assess CSM response after SRS and correlate with clinical outcomes.

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Short-Term Outcome Comparison Between the Full-Endoscopic Interlaminar Approach Versus Open Minimally Invasive Microsurgical Technique for Treatment of Lumbar Disc Herniation  Voir?

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Joint-Capsule-Like Intracranial Osteochondroma Mimicking Cystic Meningioma  Voir?

This report provides the first representative images of an intracranial osteochondroma with a cystic component mimicking cystic meningioma. A 40-year-old male presented at our outpatient clinic with decreased sensation in his right upper extremity. Preoperative computed tomography showed a tumor with a cystic-meningioma-like appearance and prominent calcifications. On magnetic resonance imaging, calcification of the lesion was suggested by the T2-weighted image; weak enhancement was seen on the T1-weighted image.

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Combined minimally invasive supraciliary and transfacial approach for large tumors with skull base and sinonasal involvement  Voir?

Tumors invading both the anterior skull base and the sinonasal area have been traditionally accessed via largely invasive open craniofacial approaches. Minimally invasive extended endoscopic endonasal approaches have recently become increasingly available, but have anatomical limitations and require incremental experience and thus high patient volume. Our objective was to assess the applicability of a novel combination of the minimally invasive supraciliary incision and the limited maxillofacial osteotomy as a combined surgical approach for large tumors invading both the anterior skull base and the sinonasal area.

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Quantitative Analysis of Intracranial Vertebrobasilar Dissecting Aneurysm with Intramural Hematoma after Endovascular Treatment Using 3T High-resolution MRI  Voir?

Quantitative measurements of intracranial vessel walls are reliable in 3T high-resolution magnetic resonance imaging (HR-MRI). However, few reports have assessed the arterial wall after endovascular treatment by 3T HR-MRI. This study aimed to quantitatively analyze vessel walls in vertebrobasilar artery dissecting aneurysms after endovascular treatment.

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The effects of combined intraoperative monitoring of abnormal muscle response and Z-L response for hemifacial spasm  Voir?

Microvascular decompression (MVD) is the most useful treatment for hemifacial spasm (HFS). During MVD surgery, abnormal muscle response (AMR) is widely used. ZL response (ZLR) is a new monitoring method for HFS. We compared the effect of AMR plus ZLR and simple AMR.
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A systematic review of radiosurgery versus surgery for neurofibromatosis type 2 vestibular schwannomas  Voir?

Neurofibromatosis type 2 (NF2) is an autosomal dominant disease characterized by bilateral vestibular schwannomas (VS). NF2-associated VS (NF2-VS) are routinely treated with microsurgery; however, stereotactic radiosurgery (SRS) has emerged as an effective alternative in recent decades. To better elucidate the role of SRS in NF2-VS, a systematic review of the literature was conducted to compare outcomes of SRS versus surgery.

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Remote Thoracic Myelopathy From a Spinal Dural Arteriovenous Fistula at the Cranio-Cervical Junction – Case Report and Review of Literature  Voir?

The cranio-cervical junction is a rare location for spinal dural arteriovenous fistulas (dAVF). Typically, fistulas at this location present with findings related to intracranial cortical venous reflux or with cervical myelopathy. We present a case of cranio-cervical junction dAVF with isolated clinical and radiographic findings of thoracolumbar myelopathy.

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Non-traumatic multiple vertebral compression fractures induced by primary hyperparathyroidism: A case report and literature review  Voir?

Primary hyperparathyroidism (PHPT) is one of the causes of osteoporosis and is known to increase the fracture risk of bone. However, multiple vertebral compression fracture due to PHPT is extremely rare.
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Radiological features and surgical strategy of hemangioblastomas with enhanced cyst wall  Voir?

Hemangioblastomas with enhanced cyst wall represent a rare radiologic presentation of hemangioblastomas with poor understandings. We aimed to summarize the clinical and radiological features, important differential diagnosis, surgical strategy and clinical outcome of this rare entity.
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Self-made, Cost-Reducing Hemostatic Agent for use in Spine Surgery  Voir?

Operative bleeding complications can lead to patient morbidity and mortality as well as longer and increased hospitalization costs. The use of matrix hemostatic sealants are commonly used to shorten the time to hemostasis, operative times and the need for blood transfusion. Commercially available hemostatic powders are used in spine surgery due to their ability to conform to wounds and decrease bleeding in difficult to access surgical sites. Hospital costs for these agents are variable and are dependent on negotiated institutional contracted prices.

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Endoscopic middle cranial fossa reconstruction via a subtemporal keyhole: A technical note  Voir?

Skull base reconstruction is an essential technique for repairing cerebrospinal fluid (CSF) leakage. A reliable method for middle cranial fossa (MCF) reconstruction with minimal invasiveness has not been reported. An initial case of endoscopic MCF reconstruction via a subtemporal keyhole is described.

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Surgical management and outcomes of intracranial chondromas: a single-center case series of 66 patients  Voir?

Management of intracranial chondromas (ICDs) is difficult. This study aims to propose a tailored management strategy based on our management of ICDs.
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Neuroprotective effects of valproic acid in a rat model of cauda equina injury  Voir?

Histone deacetylase inhibitors (HDACi), including valproic acid (VPA), are promising therapeutic interventions in neurological disorders and play an important role in synaptic activity and neuronal function.
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Spine Navigation Based on Three-Dimensional Robotic Fluoroscopy for Accurate Percutaneous Pedicle Screw Placement: A Prospective Study of 66 Consecutive Cases  Voir?

Minimally invasive spine surgery is associated with obstructed visibility of anatomical landmarks and increased radiation exposure, leading to higher incidence of pedicle screw mispositioning. To address these drawbacks, intraoperative three-dimensional fluoroscopy (io3DF) and navigation are being increasingly used. We aimed to present our dedicated multifunctional hybrid operating room (HyOR) setup and evaluate the accuracy and safety of io3DF image-guided spinal navigation in transforaminal lumbar interbody fusion with percutaneous pedicle screw (PPS) placement.

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Residual Deformity after Anterior Cervical Discectomy and Fusion for Unstable Hangman’s Fractures  Voir?

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Models of Mortality and Morbidity in Severe Traumatic Brain Injury: An Analysis of a Singapore Neurotrauma Database  Voir?

Current prognostic models for traumatic brain injury (TBI) available for use are developed from diverse historical datasets. We aim to construct a prognostication tool for severe TBI as it is this group who would benefit the most from an accurate model.
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Decompressive Cranioplasty in a Patient with Osteopetrosis: A Case Report  Voir?

Osteopetrosis is a heterogeneous group of uncommon congenital disorders that causes bony sclerosis and remodeling. Patients who are symptomatic can show significant neurological consequences with the involvement of cranial nerves and intracranial pressure (ICP) symptoms. We report an unusual case of a 26-year-old female with an autosomal-dominant type of osteopetrosis who presented with headache and severe visual deterioration, both attributed to the increased intracranial pressure. A hemi-cranioplasty was preformed, resulting in the resolution of her ICP symptoms and stabilization of her vision.

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On Protecting Young People’s Brains  Voir?

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Extensive mirror-image neurofibromas of the entire spine resulting in spastic tetraplegia  Voir?

Neurofibromatosis 1 (NF1) is associated with increased incidence of spinal tumors including neurofibromas. The majority of NF1 associated spine neurofibromas are asymptomatic, however a minority of patients will experience neurological symptoms which can range from mild paraesthesias, radiculopathy, myelopathy and focal weakness to quadriplegia in extreme cases.We present a 21 year old male diagnosed with NF1 in infancy and followed for multiple mirror-image neurofibromas involving the entire spine.

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Case report of regression of recurrent high grade glioma with temozolomide, dexamethasone and levetiracetam and review of literature.  Voir?

Treatment options for recurrent glioma of brain include chemotherapy, radiotherapy, surgery and palliation. Temozolomide appears to be effective in patients with recurrent high grade gliomas. A middle aged lady had high grade glioma of corpus callosum. Tumour was excised and chemo radiation was given. It was grade 3 anaplastic oligodendroglioma. After 5 years she had significant recurrence. They were not willing for repeat surgery or radiation. She was given temozolomide and dexamethasone intermittently and levetiracetam was continued.

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Recurrent bleeding after perimesencephalic hemorrhage  Voir?

Perimesencephalic hemorrhage (PMH) is a type of subarachnoid hemorrhage with excellent long-term outcomes. Only one well-documented case of in-hospital rebleeding after PMH is described in the literature, which occurred after initiating antithrombotic treatment because of myocardial ischemia. In this case report we describe a patient with PMH without antithrombotic treatment who had two episodes of recurrent bleeding on the day of ictus. In order to validate the radiological findings we conducted a case-control study.

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Cytotoxic and Apoptogenic Effects of Cyanidin-3-Glucoside on the Glioblastoma Cell Line  Voir?

Glioblastoma (GBM) is the most prevalent and aggressive primary cerebral tumor. Unfortunately, the median survival time is 15 months despite maximum treatment because the tumor is resistant to most therapeutic modalities. There are several studies indicating the chemopreventive and chemotherapeutic activity of cyanidin-3-glucoside (C3G) as an anthocyanin component. Therefore, this study aimed to illustrate the cytotoxic and apoptogenic effects of C3G in the U87 cell line (human GBM cell line).

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Transfer of Learning from Practicing Microvascular Anastomosis on Silastic Tubes to Rat’s Abdominal Aorta  Voir?

Learning to perform microvascular anastomosis is difficult. Laboratory practice models using artificial vessels are frequently used for this purpose. However, the efficacy of such practice models has not been objectively assessed on the performance of microvascular anastomosis during live surgical settings. This study was carried out to assess the transfer of learning from practicing microvascular anastomosis on tubes to anastomosing rat’s abdominal aorta.

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Endoscopic Endonasal Surgery for Treatment of Pituitary Apoplexy: 16 Years of Experience in a Specialized Pituitary Center  Voir?

Symptomatic pituitary apoplexy is a rare but life-threatening condition caused by sudden hemorrhage or infarction of a pituitary adenoma. In the current study, we aim to evaluate the clinical presentation, management and clinical outcomes in a cohort of patients who were treated for this condition in our center in the last 16 years.

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Prognostic factors and comparison of conservative treatment, percutaneous verteroplasty and open surgery in the treatment of spinal metastases from lung cancer  Voir?

Spinal metastases from lung cancer could result in life-threatening consequences. Few studies report the prognostic factors and compare different treatments in patients with spinal metastases from lung cancer.
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The volume of the third ventricle as a prognostic marker for shunt dependency after aneurysmal subarachnoid hemorrhage.  Voir?

Hydrocephalus is a common sequelae of aneurysmal subarachnoid hemorrhage (aSAH). In daily routine it is difficult, however, to predict a patient’s need for ventricular shunt placement in the course of the disease.
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Soluble Fms-like tyrosine kinase-1 (sFlt-1) and risk of cerebral vasospasm after aneurysmal subarachnoid hemorrhage  Voir?

The molecular mechanisms underlying cerebral vasospasm and delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (aSAH) are incompletely understood. We hypothesized that circulating anti-angiogenic factors, such as soluble Fms-like tyrosine kinase-1 (sFlt-1) and soluble transforming growth factor β (TGFβ) co-receptor, soluble endoglin (sEng), are important markers of their pathophysiology.

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Occipital artery to middle cerebral artery bypass: operative nuances  Voir?

Superficial temporal artery-middle cerebral artery (STA-MCA) anastomosis is a common procedure for vascular neurosurgeons, and it is used in a variety of diseases. However, there are cases in which the STA is absent or is too hypoplastic to be used as a donor for revascularization. Occipital artery-MCA (OA-MCA) bypass may be a treatment option in these cases.

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Surgical “Fat Patch” improves secondary intracranial hypotension orthostatic headache associated with lumbosacral dural ectasia. Case report  Voir?

Secondary intracranial hypotension is a clinical syndrome associated with the reduction of the cerebrospinal fluid volume and dural continuity violation. The main symptoms are orthostatic headache associated with nausea, vomiting, diplopia, dizziness and tinnitus. The treatment is usually non-specific.

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Staged Trapping of Traumatic Basilar Trunk Pseudoaneurysm: A Case Report and Review of Literature  Voir?

Traumatic intracranial aneurysms (TICAs) of the posterior circulation in the pediatric populations are rare. Only a few reports in literature document basilar artery TICA in the pediatric population. These cases were typically associated with a clival fracture and commonly diagnosed weeks to months after trauma. We present a case of a patient with a basilar TICA diagnosed after a motor vehicle collision treated with staged trapping and review of the literature.

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Spinal cord astrocytoma with isocitrate dehydrogenase 1 gene mutation: a case report  Voir?

In 2016, the World Health Organization (WHO) updated its classification of tumors, adding their genetic profiles to the conventional histopathological typing.
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Revascularization operation for moyamoya disease with concurrent von Willebrand disease: A case report  Voir?

Although extracranial-intracranial (EC-IC) bypass is an effective treatment strategy for symptomatic moyamoya disease, surgeons need to be cautious regarding the possibility of postoperative hemorrhagic complications in patients with a concurrent coagulation disorder. Here, we describe a case of EC-IC bypass for moyamoya disease concurrent with von Willebrand disease (vWD) type 1.

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Fluorescence behaviour and dural infiltration of meningioma analyzed by 5-ALA based fluorescence: Operating microscope versus mini-spectrometer  Voir?

To compare fluorescence intensity of tumor specimens as measured by a FGS-microscope and a spectrometer, 2.) to evaluate tumor infiltration of dura mater around meningiomas with help of these two different 5-ALA based fluorescence tools and 3.) to correlate fluorescence intensity with histopathological data.

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Fostering Student Interest in Neurological Surgery: The University of Pittsburgh Experience  Voir?

Early involvement and research in neurosurgery can increase chances for medical students to successfully matriculate into residency. This study reports the creation of a Neurological Surgery Interest Group (NSIG) at the University of Pittsburgh School of Medicine and shares its activities over two academic years.

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Intradural chordoma of the cerebellopontine angle: case report and review  Voir?

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Presurgical Administration of mTOR Inhibitors in Patients with Large Subependymal Giant Cell Astrocytoma Associated with Tuberous Sclerosis Complex  Voir?

Direct surgical resection remains the standard treatment for patients with tuberous sclerosis complex (TSC) with a large subependymal giant cell astrocytoma (SEGA). Rapamycin or everolimus is seldom used in these patients because of the risk of increased intracranial pressure and possibility of sudden death.

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Treating CSF Rhinorrhea without Dura Repair – A Case Report of Posterior Fossa Choroid Plexus Papilloma  Voir?

Choroid plexus papilloma revealed by non traumatic cerebrospinal fluid (CSF) rhinorrhea had only been described five times in the literature. The challenges in this situation are to recognize CSF leak, to rapidly understand the pathophysiology of the leak, and to choose the best treatment strategy in emergency. We report an original case of posterior fossa choroid plexus papilloma revealed by CSF leak. We then discuss the surgical strategy and the pathophysiology of CSF leak, which is explained, in this case, by both hyperproduction of CSF and local skull base erosion.

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The quantitative and functional changes of post-operative PB immune cell subsets relate to SAH patients’ prognosis: A Preliminary Study  Voir?

It has been suggested that the preoperative (PRE) and postoperative (POST) immune system alteration triggered by aneurysmal subarachnoid hemorrhage (SAH) and surgical treatment itself may affect patients’ prognosis and contribute to postoperative complications. The mechanisms maybe attributed to immune-suppression triggered infection or immune-overreaction triggered aseptic inflammation. In this study, we investigated the dynamic changes in peripheral immune cell subsets as well as the alterations of inflammatory cytokines in aneurysmal SAH patients who received craniotomy and clipping surgery.

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Effects of Transcranial Direct-Current Stimulation on Neurosurgical Skill Acquisition: A Randomized Controlled Trial  Voir?

Recent changes in surgical training environments may have limited opportunities for trainees to gain proficiency in skill. Complex skills such as neurosurgery require extended periods of training. Methods to enhance surgical training are required to overcome duty-hour restrictions, to ensure the acquisition of skill proficiency. Transcranial direct-current stimulation (tDCS) can enhance motor skill learning, but is untested in surgical procedural training. We aimed to determine the effects of tDCS on simulation-based neurosurgical skill acquisition.

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Post-Traumatic Uncal Herniation in a Conscious Patient  Voir?

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It Is Time to Reduce Free-Hand Manipulation: Case Report of Our Proposal for an Innovative 1-Step Cranioplasty  Voir?

Cranioplasty is a well-known procedure, and autologous graft bone is usually considered the best choice in this procedure, but it cannot be used in conditions such as bone-infiltrating tumors, spheno-orbital en plaque meningiomas, and bone infections. Polymethylmethacrylate (PMMA) offers great possibility of intraoperative adaption. We describe a case of 1-step cranioplasty performed in a patient with a meningeal fibrosarcoma using a custom-made silicon mold.

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Reappraisal of pediatric diastatic skull fractures in the 3-dimensional CT era: Clinical characteristics and comparison of diagnostic accuracy of simple skull x-ray, 2-dimensional CT, and 3-dimensional CT  Voir?

Diastatic skull fractures (DSFs) in children are difficult to detect in skull x-rays before they develop into growing skull fractures, and therefore little information is available on this topic. However, recent advances in 3 dimensional CT (3DCT) imaging technology enable more accurate diagnoses of almost all forms of skull fractures. The present study was undertaken to document the clinical characteristics of DSFs in children and to determine whether 3DCT enhances diagnostic accuracy.

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Regression of Pineal Lesions: Spontaneous or Iatrogenic? A Case Report and Systematic Literature Review  Voir?

Tumors arising from the pineal region account for approximately 1% of intracranial neoplasms. We present a case of a previously healthy 5-year-old boy with an acute onset of headache. A magnetic resonance imaging (MRI) scan showed a pineal mass with aqueduct compression. The patient was scheduled for tumor resection. An endoscopic third ventriculostomy was performed in advance for the treatment of hydrocephalus. Afterwards, MRI showed a relevant regression of the pineal mass without specific treatment.

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Skull Metastasis From the Liver.Case Report and Literature Review  Voir?

Calvarial metastasis from liver cirrhosis in the absence of a primary focus is exceptionally rare. Few reports of metastases from hepatocellular carcinoma of an unknown primary focus have been published.
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Guidewire Breakage During Cavernous Sinus Sampling: A Rare Complication and Its Treatment  Voir?

Venous sampling methods are valuable tools for the diagnosis of pituitary adenomas. However, these interventions also have complications, which may complicate the treatment process.
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Angiomatous meningioma have a very benign outcome despite frequent peritumoral edema at onset  Voir?

Angiomatous meningioma (AM) is a rare subtype of meningioma characterized by highly vascular tumor tissue comprised predominantly of variable sized hyalinized blood vessels. The aim is to evaluate the clinical, radiological features of AM and the long term prognosis in a single neurosurgical center.

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Long-term outcomes of surgical treatment in181 patients with supratentorial cerebral cavernous malformation-associated epilepsy  Voir?

To evaluate the efficacy of surgery as a treatment for supratentorial cerebral cavernous malformation-associated epilepsy (SCCMAE) and determine the factors that influence outcomes.
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A Retrospective Study of Thoracolumbar Fractures Treated with Fixation and Non-fusion Surgery of Intra-vertebral Bone Graft Assisted with Balloon Kyphoplasty  Voir?

Posterior fixation and fusion is the primary treatment for thoracolumbar fractures, although this treatment may sacrifice range of motion (ROM) to achieve stability, rather than treating the fracture itself. Two issues addressed when treating thoracolumbar fractures include 1) replacing the fractured vertebrae, especially the upper endplate of the injured vertebrae, and 2) providing strong fixation with biomechanical stability and flexibility.

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Case Study: Multimodal 18F-Fluciclovine PET/MRI and Ultrasound-Guided Neurosurgery of an Anaplastic Oligodendroglioma  Voir?

Structural MRI and histopathological tissue sampling are routinely performed as part of the diagnostic work-up of glioma patients. Due to the heterogeneous nature of gliomas, there is however a risk of undergrading caused by histopathological sampling errors. MRI has limitations in identifying tumor grade and type, detecting diffuse invasive growth, and separating recurrences from treatment induced changes. PET can provide quantitative information of cellular activity and metabolism, and may therefore complement MRI.

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Metastatic Basal Cell Adenocarcinoma of Submandibular Gland to the Spine: An Extremely Rare Condition  Voir?

Basal cell adenocarcinomas are rare malignant neoplasms of salivary glands, accounting for <1% of salivary gland tumors. Few cases of distant metastases have been reported.
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Hybrid Technique for the Treatment of Refractory Vertebrobasilar Insufficiencies  Voir?

Tortuous or occluded vertebral arteries (VAs) can make the endovascular treatment of vertebrobasilar insufficiency impractical. Bypass surgery is an option, but a craniotomy of the posterior fossa is complicated when physiologic vessels must be abandoned. We report 3 cases of refractory vertebrobasilar insufficiency with different presentations requiring problematic approaches in which the patients were treated by different hybrid strategies.

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New Technique for Chiasmapexy Using Iliac Crest Bone Graft: 2 Cases of Visual Impairment Caused by Empty Sella Syndrome  Voir?

Chiasmapexy is used to treat empty sella syndrome, and various materials are used for the elevation of the optic chiasm. However, the use of artificial substances may have the risk of graft infection, and fat and muscle may be absorbed over the long term after surgery. In addition, bone and cartilage may be unavailable in adequate amounts. Here, we describe a new technique for chiasmapexy using an iliac crest bone graft.

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Duty Hour Restrictions, Revisited: Second Year of the FIRST Trial  Voir?

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Factors Predicting Ventricle Volume Increase After Aneurysmal Clipping in Patients with Subarachnoid Hemorrhage  Voir?

Although many studies have evaluated risk factors associated with hydrocephalus after aneurysmal subarachnoid hemorrhage, specific ventricle volume changes after subarachnoid hemorrhage have not been evaluated. We sought to evaluate factors predicting ventricle volume enlargement in patients with aneurysmal subarachnoid hemorrhage by measuring ventricle volume with a validated, semiautomated tool.

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Frozen Section Can “Sharpen” or “Sand Off” the Surgeon's Knife: 2 Case Illustrations with Skull Base Meningioma Mimics  Voir?

Lesions at the skull base warrant careful evaluation of imaging and meticulous preoperative planning. Unnecessary radical resection of these lesions could add to surgical morbidity. Occasionally, dural-based inflammatory or infectious lesions at this site radiologically mimic meningiomas, which are commonly encountered entities at this site. Not all lesions require excision, and it could be harmful in a few cases.

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Pattern of Corticospinal Projections Defined by Brain Mapping During Resective Epilepsy Surgery in a Patient with Congenital Hemiparesis and Intractable Epilepsy  Voir?

Congenital or early-onset brain structural lesions often cause contralateral hemiparesis, cognitive deficits, developmental delays, and seizures. Seizure is the most debilitating condition, as it greatly impairs quality of life in both the affected individuals and their caregivers and prevents them from active social participation.

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Staged Endovascular Occlusion of a Posterior Communicating Artery-Cavernous Sinus Fistula and a Basilar Artery-Cavernous Sinus Fistula Associated with Traumatic Pseudoaneurysms: Technical Consideration and Literature Review  Voir?

Traumatic injury of the posterior communicating artery or the basilar artery causing arteriovenous fistulae is rare.
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T1-T2 Herniated Disk Presenting with Horner Syndrome  Voir?

The incidence of thoracic disk herniation is estimated to be 1000 to 1,000,000. Upper thoracic disk herniation is an exceedingly rare pathology with unique neurologic features. We report a case of a young patient who presented with Horner syndrome caused by a T1-T2 disk herniation.
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The Role of Antibiotic Prophylaxis in Shunt Surgery  Voir?

To determine whether antibiotic prophylaxis (AP) can reduce the postoperative infection rate and identify the risk factors for postoperative infection in shunt surgery.
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Comparison of porcine and bovine collagen dural substitutes in posterior fossa decompression for Chiari I malformation in adults  Voir?

Posterior fossa decompression surgeries for Chiari malformations are susceptible to post-operative complications such as pseudomeningocele, external cerebrospinal fluid (CSF) leak, and meningitis. Various dural substitutes have been employed to improve surgical outcomes.
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Comparison of different sequences of MRI and Ultrasongram with Nerve Conduction Studies in peripheral neuropathies  Voir?

Peripheral neuropathies refer to a group of disorders in which there is damage to the nerves of the peripheral nervous system. Electrophysiological studies are the main stay for the diagnosis of peripheral neuropathies. However, direct visualization of the nerves is possible with exact localization of site of pathology with high resolution ultrasonogram and 3 Tesla MRI scanner, and newer MR sequences.

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Mastoid Epidermoid Tumor and Associated Dural Arteriovenous Fistula with Venous Sinus Occlusion  Voir?

Dural arteriovenous fistula (DAVF) is an abnormal vascular connection between arterial and venous channels within dura mater. Although DAVFs have been linked to other types of intracranial tumors, this is the first case reporting the association between DAVF and an epidermoid tumor.
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Anatomy of Alar Ligament Part III: Biomechanical Study  Voir?

Four layers of ligamentous stabilizers comprise the craniocervical junction, and the second layer is composed of apical and paired alar ligaments. The purpose of this study is to establish the tensile strength of the alar ligaments for better understanding the implications that can arise from trauma and other pathologies in the craniocervical region.

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Medial Tentorial Dural Arteriovenous Fistula Embolization: Single Experience with Embolic Liquid Polymer SQUID and Review of the Literature  Voir?

Tentorial dural arteriovenous fistulas (DAVFs) are uncommon, complex fistulas located between the leaves of the tentorium cerebelli with a specific anatomic and clinical presentation characterized by high hemorrhagic risk. We present a rare case of a medial tentorial DAVF successfully managed via transarterial embolization using SQUID liquid polymer.

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Identification of the facial nerve in relation to vestibular schwannoma using preoperative diffusion tensor tractography and intraoperative tractography-integrated neuronavigation system  Voir?

Preoperative visualization of the facial nerve could help neurosurgeons to prevent facial nerve injury during the vestibular schwannoma (VS) surgery. Some studies have addressed diffusion tensor tractography (DTT) for preoperative identification of the facial nerve. However, few studies have focused on tractography-integrated neuronavigation for DTT verification. This study aimed to explore the appropriate DTT tracing parameters and evaluate the effect of intraoperative facial nerve tractography-integrated neuronavigation for verifying the DTT accuracy.

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Pilot Use of a Novel Tool to Assess Neurosurgical Capacity in Uganda  Voir?

There is a significant burden of unmet surgical need in many low- and middle-income countries (>80% in parts of Africa). This need is even larger for specialties such as neurosurgery. Surgical capacity tools have been developed and used to assess needs and plan for resource allocation. This study piloted a new tool to assess neurosurgical capacity and describes its use.

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Single center experience of Mechanical thrombectomy with the Trevo XP ProVue 6×25 mm stent retriever in MCA occlusion : Comparison with Trevo XP ProVue 4×20 mm  Voir?

There are a few studies assessing the suitable stent size for mechanical thrombectomy in MCA occlusion. So, the authors attempted to determine what size of a stent is suitable for thrombectomy in MCA occlusion through a comparison of Trevo XP 6×25 mm and 4×20 mm stents.
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Anatomy of Alar Ligament Part I: Morphometrics and Variants  Voir?

The alar ligaments are among the primary ligamentous structures contributing to craniovertebral stability. The purpose of this study is to clarify the morphology of the alar ligament using fresh cadaveric specimens.
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Endovascular Thrombectomy Alone versus Combined with Intravenous Thrombolysis  Voir?

To date, no randomized trial has directly addressed the question of whether intravenous (IV) tissue plasminogen activator (tPA) improves outcomes in IV tPA-eligible patients who will eventually undergo endovascular therapy (EVT), or whether a direct EVT strategy is equally effective. We performed a systematic review and meta-analysis to compare the efficacy and safety of direct EVT versus endovascular treatment with IV tPA (EVT+IV tPA) in adults with acute ischemic stroke.

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Thoracic arachnoid cyst made symptomatic by demyelination  Voir?

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Nontuberculous Antineutrophil Cytoplasmic Antibody–Positive Pachymeningitis Presenting as High Cervical Myelopathy  Voir?

High cervical myelopathy is a common entity and often encountered in clinical practice. Various pathologies can present with this symptomatology. Detailed history and a meticulous neurological examination can help us differentiate and rule out some of the close differentials. Non tuberculous ANCA positive pachymeningitis is a rare entity and a diagnosis of exclusion or following histopathological confirmation. Here we describe a case of high cervical myelopathy, the presentation, imaging and the various differentials considered and how we arrived at the diagnosis.

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Intradural-extramedullary capillary hemangioma with acute bleeding, case report and literature review  Voir?

Capillary hemangiomas are benign vascular tumors. They are commonly founded in the vertebral bodies but very seldom in the spinal cord. The most common symptom at onset is long-lasting axial pain without neurologic deficit. In rare cases, the onset may be acute with neurological deficit due to an intratumoral hemorrhage.We report a case of a 58-year-old male with a history of 15 days upper back pain triggered by a mild traumatism that evolves acutely to paraplegia and urinary and fecal retention.

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Rescue Implantation of Expandable Cages for Severe Osteolysis and Cage Dislocation in the Lumbosacral Junction  Voir?

Osteolysis and implant loosening are commonly encountered problems after spinal instrumentation.
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Application of 3-Dimensional Printing in a Case of Osteogenesis Imperfecta for Patient Education, Anatomic Understanding, Preoperative Planning, and Intraoperative Evaluation  Voir?

The techniques and applications of 3-dimensional (3D) printing have progressed at a fast pace. In the last 10 years, there has been significant progress in applying this technology to medical applications. We present a case of osteogenesis imperfecta in which treatment was aided by prospectively using patient-specific, anatomically accurate 3D prints of the calvaria. The patient-specific, anatomically accurate 3D prints were used in the clinic and in the operating room to augment patient education, improve surgical decision making, and enhance preoperative planning.

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Cervical Cord-Canal Mismatch: A New Method for Identifying Predisposition to Spinal Cord Injury  Voir?

The risk for spinal cord injuries (SCIs) ranging from devastating traumatic injuries, compression due to degenerative pathology, and neurapraxia is increased in patients with congenital spinal stenosis. Classical diagnostic criteria include an absolute anteroposterior diameter of <12-13mm or a Torg-Pavlov Ratio of <0.80-0.82; however, these factors do not take into account the size of the spinal cord, which varies across patients independent of canal size. Recent large MRI studies of population cohorts have allowed newer methods to emerge that account for both cord and canal size by measuring a spinal cord occupation ratio (SCOR).

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Syringo-Subarachnoid Shunt for the Treatment of Persistent Syringomyelia Following Decompression for Chiari Type I Malformation: Surgical Results  Voir?

Approximately 30% of patients treated with foramen magnum decompression (FMD) for Chiari I–associated syringomyelia will show persistence, recurrence, or progression of the syrinx.
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Open Versus Minimally Invasive Surgery for Extraforaminal Lumbar Disk Herniation: A Systematic Review and Meta-Analysis  Voir?

Extraforaminal disk herniation (EDH) accounts for 3%–11% of all disk herniations. Despite the heterogeneity of spinal procedures, there is a paucity of literature comparing the outcomes from different surgical approaches.
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The Top-100 Most-Cited Articles on Meningioma  Voir?

There is an abundance of articles published on meningioma.
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Cell Therapy as a New Approach to the Treatment of Posttraumatic Syringomyelia  Voir?

Cell transplantation with autologous bone marrow–derived mesenchymal stromal cells (MSCs) seems to be a therapeutic promise for patients with established spinal cord injury, achieving improvement in their quality of life, but there is no experience with the application of this type of cell therapy in patients suffering posttraumatic syringomyelia.

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Unusual Magnetic Resonance Imaging Findings of a Glioblastoma Arising During Treatment with Lenvatinib for Thyroid Cancer  Voir?

Glioblastoma (GBM) is a lesion radiologically characterized by magnetic resonance imaging findings, such as ring enhancement with extensive perifocal edema and a butterfly appearance extending into the bilateral lobes. However, these characteristic findings could be changed by antiangiogenic therapy, with decreased contrast enhancement and improved perifocal edema. Herein, we report a case of GBM that arose during treatment with a tyrosine kinase inhibitor for another cancer.

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Significance of the tentorial alignment in protecting the occipital lobe through the Poppen approach for tentorial or pineal area meningiomas  Voir?

We aimed to identify the factors that can predict the risk of occipital lobe damage preoperatively when resecting tumors located at the tentorial or pineal regions through the occipital-transtentorial approach (Poppen approach).
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Erratum to “Mortality-Associated Characteristics of Patients with Traumatic Brain Injury at the University Teaching Hospital of Kigali, Rwanda” [World Neurosurgery 102 (2017) 571–582]  Voir?

The publisher regrets that the intended order of authors was printed in error. Catherine A. Staton is the principal investigator for this study and should be listed as last author of this manuscript, Nathan M. Thielman should be the second to last author.
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Corrigendum to “Characteristics of Cervical Spine Trauma in Patients with Ankylosing Spondylitis and Ossification of the Posterior Longitudinal Ligament” [World Neurosurgery 96 (2016) 202–208]  Voir?

The authors regret that the Conflict of interest statement in this paper contained an error. The grant number for the Institute for Information & Communications Technology Promotion (IITP) grant funded by the Korea government (MSIP) was given as ‘R0190-16-02072’, however it should have been ‘R0190-16-2072’

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Metastatic Cardiac Angiosarcoma to the Lung, Spine, and Brain: A Case Report and Review of the Literature  Voir?

Metastatic angiosarcoma to the brain is a rare entity without an established management protocol.
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Ruptured Vertebral Artery Dissecting Aneurysm Concurrent with Spontaneous Cervical Internal Carotid Artery Dissection: A Report of Three Cases and Literature Review  Voir?

Multiple dissections rarely occur with ruptured vertebral artery dissecting aneurysms (VADAs). Here we report 3 cases of ruptured VADA concurrent with spontaneous cervical internal carotid artery (ICA) dissection.
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Seeding of Abdomen with Primary Intracranial Hemangiopericytoma by Ventriculoperitoneal Shunt: Case Report  Voir?

Ventriculoperitoneal shunt (VPS) placement has been implicated in extraneural metastasis of many primary central nervous system tumors. Reported cases include, but are not limited to, medulloblastoma, germ cell tumor, astrocytoma, oligodendroglioma, lymphoma, ependymoma, melanoma, and choroid plexus tumors. However, a literature review reveals no reported cases of extraneural metastasis of solitary fibrous tumor/hemangiopericytoma (SFT/HPC).

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IgG4-Related Disease: A New Etiology Underlying Diffuse Intracranial Dilating Vasculopathy  Voir?

Diffuse intracranial aneurysmal vasculopathy is a rare condition, previously described in patients with human immunodeficiency virus infection. IgG4-related disease (IgG4-RD) is a recognized inflammatory disease of systemic organs, leading to fibrosis of connective tissues. It also has been linked to inflammatory dilating aortic aneurysms, coronary vascular disease, hypophysitis, orbital pseudotumor, and pachymeningitis. It has not yet been described as a cause of diffuse intracranial dilating vasculopathy.

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Anatomy of the Alar Ligament: Part II: Variations of Its Attachment onto the Dens  Voir?

Various authors have described the morphology of the alar ligaments; however, there are no reports of a cadaveric study focusing on their attachments onto the dens. The purpose of this study was to use fresh cadaveric specimens to describe in detail different attachment patterns of the alar ligaments onto the dens.

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Bevacizumab Plus Radiosurgery for Nonsquamous Non–Small Cell Lung Cancer Patients with Brain Metastases: Safe Combination?  Voir?

In the context of bronchial cancers, the brain is one of the most frequent sites for metastases. Local treatments of these metastases have evolved and are often combined to obtain greater efficiency, while the main objective remains to reduce the symptoms. Radiosurgery is currently used as a primary option for patients harboring few numbers of small to middle-sized brain metastases. In nonsquamous non–small cell lung cancer (NSCLC), chemotherapy is often associated with bevacizumab. Our goal was to assess the safety of this early combination.

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Ewing Sarcoma of the Cervical Epidural Space Presenting with Tetraplegia: Case Report and Review of Literature  Voir?

Ewing sarcoma (ES) is among the most frequented extremity osseous tumor in childhood. It was first described by James Ewing as diffuse endotheliomas in 1921. The name Ewing sarcoma was coined by Oberling in 1928 as a tribute to the legend who described this disease. ES exists in osseous and extraosseous forms. It shares much of its molecular typing with primitive neuroectodermal tumor (PNET); hence, they are regarded as different ends of the same molecular spectrum. ES, extraosseous ES, PNET, and Askins tumor are the other members of this family termed the Ewing sarcoma family of tumors.

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Rhabdoid Meningioma Arising Concurrent in Pulmonary and Intracranial with a Rare Malignant Clinical Progression: Case Report and Literature Review  Voir?

Rhabdoid meningioma (RM) is an unusual variant of meningioma, classified as World Health Organization grade III. Although its recurrence is common, extracranial metastasis is rare and usually misdiagnosed. The transfer mechanism and pathway are ambiguous; once the metastasis occurs, the prognosis is poor, and there is no effective management. The present case is the first report of concurrent intracranial and pulmonary RM with rapid and widespread metastasis. We hope this report can serve as a helpful reference for clinicians and radiologists.

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Varied Spectrum of Supratentorial Arteriovenous Malformations: Technical Challenges  Voir?

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A new volumetric radiological method to assess indirect decompression after XLIF using a high resolution intraoperative CT  Voir?

Two-dimensional radiographic methods have been proposed to evaluate the radiographic outcome after indirect decompression through XLIF. However, the assessment of neural decompression in a single plane may underestimate the effect of indirect decompression on central canal and foraminal volumes.The present study aimed to assess the reliability and consistency of a novel 3D radiographic method, which assesses neural decompression by volumetric analysis utilizing a new generation of intraoperative fan-beam CT scanner in patients undergoing XLIF.

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Preservation of Motor Function After Resection of Lower-Grade Glioma at the Precentral Gyrus and Prediction by Presurgical Functional Magnetic Resonance Imaging and Magnetoencephalography  Voir?

Intra-axial brain tumors located at anatomically eloquent areas are challenging conditions. On one hand, it is often difficult to pursue maximum extent of resection of tumor in these locations. On the other hand, neuroplasticity occurs in some patients with low-grade glioma, and the primary neural functions are known to sometimes shift from conventional “eloquent cortices.”

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Discovery of Aquaporin-1 and Aquaporin-4 Expression in an Intramedullary Spinal Cord Ependymal Cyst: Case Report  Voir?

Intramedullary ependymal cysts of the spinal cord are rare, benign, fluid-filled cysts usually situated along the ventral surface of the spinal cord. Only 32 cases have been reported since they were first described. Thus, owing to the rarity at which these cysts are encountered, their management and pathogenesis remain controversial. Whereas some investigators have advocated for cystosubarachnoid shunt placement for symptomatic ependymal cysts, others have argued for complete cyst resection or simple fenestration.

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Rosette-Forming Glioneuronal Tumor of the Fourth Ventricle in Children: Case Report and Literature Review  Voir?

Rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle is a rare World Health Organization (WHO) grade I neoplasm. Gross total resection (GTR) is the treatment of choice, and there is no firm evidence supporting other treatment options when GTR is not feasible.
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The Application of a Three-Dimensional Printed Product to Fill the Space After Organ Removal  Voir?

Maintaining body integrity, especially in Asian societies, is an independent predictor of organ donation.
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First Case of Autonomic Dysreflexia Following Elective Lower Thoracic Spinal Cord Transection in a Spina Bifida Adult  Voir?

Spinal cord transection is a radical but effective treatment for highly selective cases of symptomatic spinal retethering in paraplegic spina bifida patients. Autonomic dysreflexia (AD) is a potentially life-threatening syndrome involving a dysregulated sympathetic discharge reflex commonly seen following cervical and high thoracic spinal cord injury, leading to a disconnect between autonomic pathways above and below the lesion that can lead to severe complications including uncontrolled hypertension, bradycardia, stroke, and potentially death.

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Malignant Cerebral Swelling After Cranioplasty due to Ipsilateral Intracranial Vasculopathy: Case Report and Literature Review  Voir?

Cranioplasty is a well-established surgical operation that is used worldwide for patients with skull defects following decompressive craniectomy (DC). However, in some cases, potentially fatal complications may occur, such as malignant cerebral swelling after uneventful cranioplasty.
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Local Fibrinolytic Therapy for Intraventricular Hemorrhage: A Meta-Analysis of Randomized Controlled trials  Voir?

The safety and efficacy of intraventricular fibrinolysis (IVF) in patients with intraventricular hemorrhage (IVH) are unclear. We aimed to determine these issues and to evaluate whether there are differences between recombinant tissue-plasminogen activator (rt-PA) and urokinase according to subgroup analyses.

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Anatomic dissection of arachnoid membranes encircling the pituitary stalk on fresh non formalin fixed specimens: anatomo-radiologic correlations and clinical applications in craniopharyngioma surgery  Voir?

The anatomy of the arachnoid membranes and cisternal spaces around the pituitary stalk has not been yet exhaustively described and understood. In this study we performed a detailed anatomic study on fresh non formalin fixed cadavers of the arachnoid membranes encircling the pituitary stalk and correlate our anatomic findings with MRI.

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Takotsubo Cardiomyopathy Triggered by Venous Air Embolism During Craniotomy in the Sitting Position  Voir?

We present a case of stress-induced cardiomyopathy (Takotsubo cardiomyopathy) caused by a venous air embolism during a craniotomy performed in the sitting position.
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Cochlear Nerve Action Potential Monitoring for Preserving Function of an Unseen Cochlear Nerve in Vestibular Schwannoma Surgery  Voir?

Intraoperative monitoring of cochlear nerve action potential (CNAP) has been used in patients with small vestibular schwannoma (<15 mm) to preserve cochlear nerve function. We performed surgery for a larger vestibular schwannoma under CNAP monitoring with the aim of preserving cochlear nerve function, and compared the data with findings from 10 patients with hemifacial spasm who underwent microvascular decompression surgery.

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External Ventricular Drainage Preceding the Removal of a Nail from the Intracranial Space as a Safe Management Strategy for Predicted Secondary Intraventricular Hemorrhage  Voir?

Intracranial nail gun injury is a rare traumatic event and can result from a suicide attempt. Cerebral angiography is essential in the evaluation of damage to the intracranial vessels, and surgical removal of nails is generally the optimal treatment. Intraventricular hemorrhage can happen after removal of intracranial nails. Endovascular surgery or intraoperative computed tomography has been reported to be useful for detection and treatment of intraventricular hemorrhage. After the surgical removal of nails, attention should be paid for complications such as pseudoaneurysm and infection.

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Use of Sodium Fluorescein in Meningioma Surgery Performed Under the YELLOW-560 nm Surgical Microscope Filter: Feasibility and Preliminary Results  Voir?

To evaluate the feasibility of sodium fluorescein (Na-Fl)–guided surgery involving the use of the PENTERO 900 surgical microscope equipped with the YELLOW-560 nm filter and low-dose Na-FL (200 mg/2–4 mg/kg) in meningioma surgery.
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Postoperative Radiculopathy Caused by a Retained Fractured Pedicle Cannulation Probe and Its Mechanism of Extraction  Voir?

Spine surgery relies heavily on technology and surgical instrumentation. Improperly used instrumentation can be detrimental to the patient. Despite multiple checkpoints to ensure that foreign bodies are not retained in surgery, numerous case reports have described retained foreign bodies; however, none of these cases involve retained instrumentation after open spine surgery. Of the retained objects, 4 were sponges and one was a Jamshidi needle fragment. Although smaller objects are more commonly the culprits, surgical instruments can break off, remain stuck, and cause clinical sequelae.

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Indeterminate Dendritic Cell Tumor in Thoracic Spine: A Case Report and Review of Literature  Voir?

Indeterminate dendritic cell tumor (IDCT) is an extremely rare hematological disorder with poorly understood pathogenesis. Occasionally encountered by hematologists, unusual presentations of IDCT have never been reported in the spine literature. The authors report a case of a 51-year-old man who presented with progressively worsening axial thoracic back pain radiating to his sides for three months. MRI revealed a large 3-cm enhancing mass at the T9 vertebral body with an exophytic component causing significant canal stenosis.

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Subdural Fluid Collection and Hydrocephalus After Foramen Magnum Decompression for Chiari Malformation Type I: Management Algorithm of a Rare Complication  Voir?

Chiari malformation type I is a hindbrain abnormality characterized by descent of the cerebellar tonsils beneath the foramen magnum, frequently associated with symptoms or brainstem compression, impaired cerebrospinal fluid circulation, and syringomyelia. Foramen magnum decompression represents the most common way of treatment. Rarely, subdural fluid collection and hydrocephalus represent postoperative adverse events. The treatment of this complication is still debated, and physicians are sometimes uncertain when to perform diversion surgery and when to perform more conservative management.

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Bevacizumab for Radiation Induced Optic Neuritis Among Aggressive Residual/Recurrent Suprasellar Tumors: More Than a Mere Antineoplastic Effect  Voir?

Angiogenesis and vascular endothelial growth factor (VEGF) have recently been implicated in animal and clinical models of radiation-induced optic nerve, retinal, and brain necrosis. Although there are isolated case reports of anti-VEGF therapy with bevacizumab for management of radiation-induced brain necrosis, there are little data defining its role in radiation-induced optic nerve damage.

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Improving the prognostic value of disease specific Graded Prognostic Assessment (ds-GPA) model for renal cell carcinoma by incorporation of Cumulative Intracranial Tumor Volume (CITV)  Voir?

We tested the prognostic value of cumulative intracranial tumor volume (CITV) in the context of ds-GPA model for renal cell carcinoma (RCC) patients with brain metastasis (BM) treated with stereotactic radiosurgery (SRS).
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Symptomatic Thoracic Nerve Root Herniation into an Extradural Arachnoid Cyst: Case Report and Review of the Literature  Voir?

Spinal extradural arachnoid cysts (SEACs) are relatively rare and usually asymptomatic. They preferentially are situated in the thoracic extradural space and almost always dorsal. SEACs may present with back pain and/or cord compression symptoms. Needle aspiration, needle fenestration, or open surgical resection/fenestration have been reported as treatment modalities.

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Histology-Stratified Tumor Control and Patient Survival After Stereotactic Radiosurgery for Pineal Region Tumors: A Report From the International Gamma Knife Research Foundation  Voir?

Pineal region tumors represent a rare and histologically diverse group of lesions. Few studies are available to guide management and the outcomes after stereotactic radiosurgery (SRS).
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Lumbosacral Transitional Vertebra: Possible Role in the Pathogenesis of Adolescent Lumbar Disc Herniation  Voir?

To investigate the role of lumbosacral transitional vertebra (LSTV) in the pathogenesis of adolescent lumbar disc herniation (ALDH) and the association between LSTV type and the herniation level of ALDH.
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Identification of Driver Genes and Key Pathways of Pediatric Brain Tumors and Comparison of Molecular Pathogenesis Based on Pathologic Types  Voir?

This study is to identify pediatric brain tumors (PBT) driver genes and key pathways to detect the expression of the driver genes and also to clarify the relationship between patients' prognosis and expression of driver genes.
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Impact of Gender Disparities on Short-Term and Long-Term Patient Reported Outcomes and Satisfaction Measures After Elective Lumbar Spine Surgery: A Single Institutional Study of 384 Patients  Voir?

There is a paucity of data determining the impact that gender disparities have on spine outcomes, particularly perception of health and satisfaction. The aim of this study was to determine whether there is a difference in 3-month and 1-year patient-reported outcomes and satisfaction after elective lumbar spine surgery.

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Traumatic Brain Injury and Mood Stabilizers: Recent Cumulative Evidence  Voir?

Traumatic brain injury (TBI) is the primary cause of morbidity and death in young adults in industrialized countries. The catastrophic effects of TBI on patients are amplified by the fact that there are few treatment options. Notably, TBI encloses an initial primary injury that mechanically injures neurons, glia, and vascular structures and is often followed by a secondary injury cascade beginning hours or days after the initial trauma (Figure 1). This secondary brain injury is complex. Its pathophysiology is puzzling and will likely require pharmacologic agents that act in a coordinated fashion to increase cell survival and decrease cell death pathways.

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Bionic-Brain: Controlling a Prosthetic Hand  Voir?

Traumatic injuries of the brachial plexus can be devastating. Usually, these injuries occur in a population who are in the most productive period of their lives, predominantly as a result of motorcycle, bicycle, or work-related accidents. The effects of a brachial plexus injury carry physical, emotional, and social strains. While surgical techniques are available to recircuit the brachial plexus, they are not always met with physical and emotional success. An opportunity exists for robotic engineering—a motorized hand replacement in select patients who are suitable for such technology.

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The Trigeminocardiac Reflex During the Anterior Transpetrosal Approach  Voir?

The anterior transpetrosal approach (ATPA), during which the trigeminal nerve (TN) is manipulated, has a risk of eliciting the trigeminocardiac reflex (TCR). The aim of this study was to assess the risk of TCR during ATPA.
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Clinical Observation of Posterior Percutaneous Full-Endoscopic Cervical Foraminotomy as a Treatment for Osseous Foraminal Stenosis  Voir?

To observe the clinical effects of posterior percutaneous full-endoscopic cervical foraminotomy in patients with osseous foraminal stenosis.
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Novel Technique of Percutaneous Fat Graft for Repair of Persistent Large Pseudomeningocele  Voir?

Pseudomeningocele is an uncommon but problematic complication in lumbar spine surgery. Initial conservative measures frequently are successful, but persistence requires additional management. The current surgical approach can involve a range of techniques, including blood patches, hydrogel/fibrin sealants, drains, open surgical repair of the dura, or a combination of the all techniques if symptoms persist. This report demonstrates a novel technique for repair via a percutaneous approach to deliver an autologous fat graft into the pseudomeningocele.

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C2 Bone Erosion Secondary to Iatrogenic Pseudomeningocele: A Case Report and Description of a Novel Surgical Technique  Voir?

Pseudomeningoceles are a rare cause of bone erosions. Development of such erosions in the C2 vertebral body and the odontoid process can lead to life-threatening instability. Treatment options to regain stability include atlantoaxial and occipitocervical fusion. For patients with a history of Chiari decompression and large C2 lesions, common fusion techniques are not always feasible. In addition, fusion surgery sacrifices physiologic motion and is therefore a disabling procedure, especially for young and active patients.

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Completion of the Circle of Willis Varies by Gender, Age, and Indication for Computed Tomography Angiography  Voir?

The circle of Willis (CoW) is the foremost anastomosis and blood distribution center of the brain. Its effectiveness depends on its completion and the size and patency of its vessels. Gender-related and age-related anatomic variations in the CoW may play an important role in the pathogenesis of cerebrovascular diseases. In this study, we analyzed computed tomography angiograms (CTAs) to assess for differences in CoW completion related to gender, age, and indication for CTA.

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The Effect of Biocomposite Screws on Bone Regeneration in a Rat Osteoporosis Model  Voir?

To evaluate the efficacy of biocomposite screws used in ovariectomy (OVX)-induced osteoporotic rats.
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Preoperative Frailty Score for 30-Day Morbidity and Mortality After Cranial Neurosurgery  Voir?

Evaluating preoperative frailty is critical for guiding shared surgical decision-making. The purpose of this study was to develop a novel preoperative frailty index for classification of adverse outcomes following cranial neurosurgery procedures.
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Finite Element Analysis of Influence of Axial Position of Center of Rotation of a Cervical Total Disc Replacement on Biomechanical Parameters: Simulated 2-Level Replacement Based on a Validated Model  Voir?

Finite element models have been widely used to predict biomechanical parameters of the cervical spine. Previous studies investigated the influence of position of rotational centers of prostheses on cervical biomechanical parameters after 1-level total disc replacement. The purpose of this study was to explore the effects of axial position of rotational centers of prostheses on cervical biomechanics after 2-level total disc replacement.

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Antibiotic Prophylaxis in Endoscopic Endonasal Pituitary and Skull Base Surgery  Voir?

Postoperative infection is a potentially dramatic consequence in endoscopic endonasal surgery. The aim of this study was to assess the efficacy of our intraoperative antibiotic prophylaxis by analyzing the risk factors of postoperative meningitis in our series.
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Shifting Treatment Paradigms for Ruptured Aneurysms from Open Surgery to Endovascular Therapy Over 25 Years  Voir?

Since the introduction of Gugliemi detachable coils in the early 1990s, major clinical studies have supported an increasing role for coil embolization of ruptured aneurysms. We assessed aneurysm location and treatment modality in aneurysmal subarachnoid hemorrhage (aSAH) over the past 25 years.
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Efficacy of Closed Continuous Lumbar Drainage on the Treatment of Postcraniotomy Meningitis: A Retrospective Analysis of 1062 Cases  Voir?

Postcraniotomy meningitis is a severe complication in neurosurgery, and can result in high morbidity and mortality. Closed continuous lumbar drainage (CCLD) as an adjuvant method for treating postcraniotomy meningitis in adults is rarely assessed. This study aimed to evaluate the efficacy of CCLD in the treatment of postcraniotomy meningitis.

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Sport-Related Structural Brain Injury: 3 Cases of Subdural Hemorrhage in American High School Football  Voir?

The risk of sport-related concussion (SRC) has emerged as a major public health concern. In rare instances, sport-related head injuries can be even more severe, such as subdural hemorrhage, epidural hemorrhage, or malignant cerebral edema. Unlike SRCs, sport-related structural brain injury (SRSBI) is rare, may require neurosurgical intervention, and can lead to permanent neurologic deficit or death. Data characterizing SRSBI are limited, and many have recognized the need to better understand these catastrophic brain injuries.

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Pathologic Progression, Possible Origin, and Management of Multiple Primary Intracranial Neuroendocrine Carcinomas  Voir?

Primary intracranial neuroendocrine carcinomas (NECs) are extremely rare malignant tumors with no previous reports of multiple ones in the literatures.
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Ventral Lumbar Synovial Cyst Causing Cauda Equina Compression: Case Report and Literature Review  Voir?

Juxtafacet spinal cysts are cystic synovial lesions that often are indistinguishable clinically or radiologically and require histopathology analysis to confirm the diagnosis. Lumbar synovial cysts usually arising from the synovium of the facet joints. They have been described posterolaterally or rarely in the posterior midline. However, we describe the first synovial cyst ventral to the dural sac.

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Intraventricular Meningioma Resection with Postoperative Ischemia of the Lateral Geniculate Nucleus  Voir?

Intraventricular meningiomas comprise 0.5%–3% of intracranial meningiomas. They often cause obstructive hydrocephalus and commonly are treated with surgical resection or stereotactic radiosurgery.
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Neurologic Outcome After Resection of Parietal Lobe Including Primary Somatosensory Cortex: Implications of Additional Resection of Posterior Parietal Cortex  Voir?

Postoperative neurologic outcomes after primary somatosensory cortex (S1) resection have not been well documented. This study was designed to evaluate the neurologic deterioration that follows resection of the S1 areas and to assess the risk factors associated with these morbidities.
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Outpatient Lumbar Microdiscectomy in France: From an Economic Imperative to a Clinical Standard—An Observational Study of 201 Cases  Voir?

The outpatient lumbar discectomy procedures have been established for more than 2 decades. However, especially in Europe, there are still obstacles to the development of these procedures, which may be related to medicoeconomic imperatives, and to several factors concerning both surgeons and patients. We describe our initial experience in introducing this method in our institution.

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A Computed Tomography–Based Comparison of Abnormal Vertebrae Pedicles Between Dystrophic and Nondystrophic Scoliosis in Neurofibromatosis Type 1  Voir?

To explore the prevalence and distribution of abnormal vertebral pedicles in scoliosis secondary to neurofibromatosis type 1 (NF1-S) and to compare the abnormal vertebrae pedicles between dystrophic and nondystrophic scoliosis.
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Survival Patterns of 5750 Stereotactic Radiosurgery–Treated Patients with Brain Metastasis as a Function of the Number of Lesions  Voir?

The number of brain metastases (BMs) plays an important role in the decision between stereotactic radiosurgery (SRS) and whole-brain radiation therapy.
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The Fate of Patients with Adult Spinal Deformity Incurring Rod Fracture After Thoracolumbar Fusion  Voir?

To report the outcome of adult spinal deformity (ASD) in patients with rod fracture (RF) after thoracolumbar fusion.
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Hemispheric Chronic Subdural Hematoma Concealing Subdural Metastases: Terrible Surprise Behind Routine Emergency Department Consultation  Voir?

The patient is a 79-year-old male, suffering from advanced metastatic prostate cancer, who developed a progressively worsening ideomotor slowing and was therefore referred to the emergency department of our institution. A plain axial computed tomography (CT) scan revealed a vast hemispheric subdural fluid collection, apparently a subdural hematoma. On closer inspection, and most of all, in hindsight, a tenuously isohyperdense signal irregularity at the frontal aspect of the fluid collection appears.

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Isolated Subcallosal Artery Infarction Secondary to Localized Cerebral Vasospasm of Anterior Communicating Artery Complex Following Subarachnoid Hemorrhage  Voir?

Subcallosal artery (ScA) infarction is a well-recognized but uncommon complication of surgical treatment of anterior communicating artery aneurysms.
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Microneurosurgical Clip Ligation of Acutely Ruptured Cerebral Aneurysm Immediately Preceded by Intentional Subtotal Endovascular Coil Embolization Under a Single Anesthesia: Observations Using a Deliberate Combined Sequential Treatment Strategy in 13 Cases  Voir?

Endovascular coil embolization and craniotomy with clip ligation are the 2 most commonly used treatments for ruptured cerebral aneurysm. Although coiling maintains the advantages of brevity and complete avoidance of brain retraction and manipulation, clipping offers the benefits of decompression of the injured brain and lower rates of aneurysm recurrence. A combined, immediately sequential treatment strategy for acutely ruptured cerebral aneurysm that simultaneously maximizes the advantages of both techniques, while minimizing their respective disadvantages, may be a useful paradigm.

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Nocardia farcinica Brain Abscess: Report of 3 Cases  Voir?

Central nervous system nocardial infection is a rarely reported disease that usually affects patients with predisposing and debilitating conditions but also the immunocompetent population. The most common variant affecting the brain is Nocardia farcinica. Management of brain nocardiosis is troublesome and requires consideration of the severity of the underlying systemic disease, the difficulties in identifying the bacterium, and the frequent delay in initiating adequate therapy.

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Intramedullary Spinal Cord Metastasis from Ovarian Cancer in a 50-Year-Old Female  Voir?

Intramedullary spinal cord metastasis (ISCM) from ovarian cancer is rare. Here we report a case of a 50-year-old female with ISCM from ovarian cancer.
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Iatrogenic Ascending Pharyngeal Artery Injury by Predilation Balloon Inflation During Carotid Artery Stenting with Flow Reversal  Voir?

The ascending pharyngeal artery (APA) may rarely arise from the common carotid artery bifurcation. We report an injury to the APA as an unusual complication of predilation balloon inflation during carotid artery stenting (CAS) with flow reversal.
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Endoscopic Endonasal Transsphenoidal Approach for the Removal of Optochiasmatic Cavernoma: Case Report and Literature Review  Voir?

Cavernoma of the optic chiasm is a rare disease, and the most common clinical presentation is chiasmal apoplexy. Almost all the cases reported in the literature were treated surgically with craniotomy.
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Design-Based Comparison of Spine Surgery Simulators: Optimizing Educational Features of Surgical Simulators  Voir?

Simulation-based education has made its entry into surgical residency training, particularly as an adjunct to hands-on clinical experience. However, one of the ongoing challenges to wide adoption is the capacity of simulators to incorporate educational features required for effective learning. The aim of this study was to identify strengths and limitations of spine simulators to characterize design elements that are essential in enhancing resident education.

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Cerebral Vasospasm–Dependent and Cerebral Vasospasm–Independent Cerebral Infarctions Predict Outcome After Nonaneurysmal Subarachnoid Hemorrhage: A Single-Center Series with 250 Patients  Voir?

The number of patients with nonaneurysmal subarachnoid hemorrhage (naSAH) has increased during the last decade. Data regarding infarctions in naSAH are still limited. The aim of this study was to identify the rate of cerebral vasospasm (CVS)-dependent and CVS-independent infarctions and their influence on clinical outcomes.

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Initial Treatment Strategy for Intracranial Mycotic Aneurysms: 2 Case Reports and Literature Review  Voir?

Intracranial mycotic aneurysm (IMA) is a rare neurovascular disease and a well-known complication after infective endocarditis. IMAs potentially carry a high mortality risk resulting from intracranial hemorrhage. Therefore, initial treatment is crucial for IMA patients, but an optimal treatment strategy remains unknown. Herein, we report 1 cases of IMA patients treated with the current usual modalities, and we provide a comprehensive literature review to propose an optimal initial treatment strategy for IMAs.

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An Intraoperative Look at a Residual/Recurrent Tentorial Dural Arteriovenous Fistula  Voir?

Dural arteriovenous fistulas (dAVFs) often are treated via transarterial or transvenous embolization. Incomplete penetration of the draining vein/occult residual often will become apparent on follow-up angiography, requiring repeat embolization, or at times, surgical resection.
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Clival Defect with Primary CSF Rhinorrhea: A Very Rare Presentation with Challenging Management  Voir?

Primary spontaneous cerebrospinal fluid (CSF) rhinorrhea due to clival defect is an extremely rare presentation, and only 6 cases have been reported in the literature so far17.
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Primary Intradural Extramedullary Cervical Spinal Cysticercosis  Voir?

Spinal cysticercosis has been reported in 0.7%–3.0% of patients with neurocysticercosis. Most patients with spinal cysticercosis have a coexisting intracranial disease. Most often this intracranial disease manifests as intradural extramedullary lesions involving thoracic and lumbar regions or intramedullary lesions. Intradural extramedullary primary spinal cysticercosis manifesting as cervical myelopathy is extremely rare and has not been reported to date.

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Transventricular Migration of Neurocysticercosis  Voir?

The movements of a neurocysticercosis cyst within the ventricular cavity have been identified rarely.
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Cerebral Venous Sinus Thrombosis Secondary to Idiopathic Hypertrophic Cranial Pachymeningitis: Case Report and Review of Literature  Voir?

Idiopathic hypertrophic cranial pachymeningitis (IHCP) is a rare fibrosing inflammatory process involving the dura mater. Currently, there is no consensus on the treatments for IHCP, and the usefulness of immunosuppressive agents as a first-line option remains controversial. Cerebral venous sinus occlusion (CVSO) and cerebral venous sinus thrombosis (CVST) secondary to IHCP, which may cause progressive intracranial hypertension and venous obstructive parenchymal lesions, make the diagnosis and treatment of IHCP more complicated.

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Infection or Glioma? The False Dilemma of Primary Central Nervous System Histiocytic Sarcoma  Voir?

Primary central nervous system (CNS) histiocytic sarcoma is an extremely rare lymphoproliferative disorder that affects the CNS and behaves aggressively. Only 27 cases of primary CNS histiocytic sarcoma have been reported. The paucity of literature on this entity has made diagnosis and treatment difficult both for the surgeon and the pathologist.

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Trans-Anterior Communicating Artery Primary Stenting in Acute Tandem Middle Cerebral Artery–Internal Carotid Artery Occlusion Due to Thoracic Aortic Stent Graft  Voir?

The main target of stroke intervention is the revascularization of occluded vessels, usually achieved with thrombectomy or thrombus aspiration. Despite good results in limited series, intracranial primary stenting is controversial for increased hemorrhagic risk owing to the need for dual antiplatelet therapy.

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Image Guidance to Aid Pedicle Screw Fixation of a Lumbar Fracture-Dislocation Injury in a Toddler  Voir?

Pedicle screw fixation of the lumbar spine in children age <2 years is particularly challenging, as successful cannulation of the small pedicle dimensions requires a high level of precision and there are no implants specifically designed for the infant spine. Image-guided navigation is commonly used in adult spinal surgery and may be particularly helpful for the placement of spinal screws in areas where the bony anatomy is small and/or anatomically complex, as in the upper cervical area.

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Preoperative Embolization and Complete Tumoral Resection of a Cervical Aggressive Epithelioid Osteoblastoma  Voir?

Epithelioid “aggressive” osteoblastoma (EOB) is a rare and more aggressive subtype of osteoblastoma (OB) with a higher recurrence rate, greater risk of malignant transformation, larger size, and greater intraoperative blood loss. The present case report illustrates that preoperative angioembolization of an EOB can be safely performed with low intraoperative blood loss.

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Intradural Intramedullary Teratoma Presenting in the Lumbar Spine: Report of a Rare Case  Voir?

Intradural teratomas are an exceedingly unusual phenomenon. They are tumors with the cellular constituent source of all the 3 germ cell layers.
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Treatment Strategies of Subarachnoid Hemorrhage from Bilateral Vertebral Artery Dissection: A Case Report and Literature Review Focusing on the Availability of Stent Placement  Voir?

Bilateral vertebral artery dissection (VAD) may result in subarachnoid hemorrhage (SAH). However, a variety of factors contribute to the difficulties with treating SAH. We report a case of bilateral VAD with SAH, as well as a literature review.
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Incidental Primary Intradural Carcinoid Tumor in a Patient with Lumbar Radiculopathy  Voir?

Carcinoid tumors are neuroendocrine neoplasms derived from enterochromaffin cells. Central nervous system involvement is rare. The reported cases include metastases to brain or spinal cord, and primary skeletal or extradural disease resulting in compressive myeloradiculopathy. There are 2 previously reported cases of primary intradural extramedullary carcinoid tumor, presenting with compressive symptoms. We report the first case of primary incidental intradural extramedullary carcinoid tumor.

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Recurrent Pituicytoma with Pseudoaneurysm: Report of a Challenging Case  Voir?

Pituicytoma is a rare tumor originating from glial cells of the adult neurohypophysis and infundibulum. Surgical removal is the treatment of choice for this neoplasm. In recent years the endoscopic endonasal approach has proven to be a viable and effective alternative to standard craniotomy.
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A Hemorrhagic Clival Chordoma with a Long Progression-Free Survival  Voir?

Chordomas and ecchordosis physaliphora may on rare occasions present with intracranial hemorrhage. Their distinction usually relies on the results of the Ki-67 proliferative index, with a result lower than 1% favoring ecchordosis physaliphora. Intracranial hemorrhagic chordomas have been linked to unfavorable prognosis, due to acute neurologic deterioration and death, or progression after treatment. To the best of our knowledge, this is the first report of a patient with an intracranial hemorrhagic chordoma who had a long progression-free survival.

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Microsurgical Repair of Ruptured Aneurysms Associated with Moyamoya-Pattern Collateral Vessels of the Middle Cerebral Artery: A Report of Two Cases  Voir?

Patients with Moyamoya or other intracranial steno-occlusive disease are at risk for developing aneurysms associated with flow through collateral vessels. Because these lesions are rare, the optimal management remains unclear. Here, we describe 2 cases of microsurgical repair of ruptured collateral vessel aneurysms associated with middle cerebral artery (MCA) occlusion.

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Intramedullary Cervical Spinal Cord Abscess  Voir?

Intramedullary spinal cord abscesses are rarely encountered in modern neurosurgical practice. Select patients are at high risk for developing an intramedullary spinal cord abscess, which can result in acute neurologic deficits. Patients with failed conservative management may benefit from early surgical intervention; however, the evidence is limited by level 3 studies. In this case presentation, the patient failed conservative management for a cervical intramedullary spinal cord abscess and developed acute neurologic deficits.

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Corrigendum to “Clinical Outcomes of Correcting Cervical Deformity in Cerebral Palsy Patients” [World Neurosurgery 96 (2016) 500–509]  Voir?

The authors regret that the Conflict of interest statement in this paper contained an error. The grant number for the Institute for Information & Communications Technology Promotion (IITP) grant funded by the Korea government (MSIP) was given as ‘R0190-16-02072’, however it should have been ‘R0190-16-2072’.

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A Primary Pigmented Choroid Plexus Papilloma Located Within the Sella Turcica: Case Report and Literature Review  Voir?

Choroid plexus papillomas (CPPs) are rare benign tumors, and the pigmented subtype is observed even more rarely.
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Endovascular Therapy for the Steal Phenomenon due to the Innominate Artery Severe Stenosis and Bilateral Internal Carotid Artery Severe Stenosis  Voir?

Symptomatic innominate artery stenosis presenting as hemodynamic bilateral cerebral ischemia is uncommon. We present a rare case of the severe stenosis of the origin of an innominate artery and severe stenosis of bilateral internal carotid artery that induced hemodynamic cerebral ischemia after ipsilateral axillary artery-bilateral femoral artery bypass and was treated with stent replacement of the innominate artery and right internal carotid artery.

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Rupture After Bypass and Distal Occlusion of Giant Anterior Circulation Aneurysms  Voir?

Giant aneurysms are very high-risk lesions both in terms of natural history and treatment. Bypass with distal occlusion is thought to be a safe treatment option for these aneurysms. Here, we report 2 cases of aneurysm rupture after bypass and distal occlusion, review the literature, and discuss the possible underlying mechanisms, in the hopes of influencing treatment planning and averting such complications in the future.

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Concomitant Lumbosacral Perimedullary Arteriovenous Fistula and Spinal Dural Arteriovenous Fistula  Voir?

Although multifocal spinal arteriovenous malformations (AVMs) have been reported before, the present case is the first case of 2 different types, including 1 perimedullary arteriovenous fistula and 2 spinal dural arteriovenous fistulas of lumbosacral AVMs, coexisting in 1 patient. We also report the use of hybrid techniques in treatment of concomitant lumbosacral spinal AVMs.

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Pial-Dural Intracranial Arteriovenous Fistula with Flow-Associated Aneurysmal Rupture—Case Report with Review of Literature and Proposal on the Mechanism of Hemorrhage and Treatment Options  Voir?

Vascular anomalies in the form of dural arteriovenous fistulas (DAVFs), arteriovenous malformations, and aneurysms are well described in the literature. Pial arteriovenous fistulas (PAVFs) are described to a lesser extent in the literature. When these anomalies are combined, diagnosis and treatment become complex.

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Cervical Burst Fracture in a Patient with Contiguous 2-Level Cervical Stand-Alone Cages  Voir?

Cervical stand-alone interbody cages have seen increasingly wider use over the plate-and-screw construct in single-level anterior cervical discectomy and fusion (ACDF) in the treatment of cervical disc herniation and degenerative spondylotic conditions. Despite positive clinical outcomes, the efficacy and safety of using these devices in contiguous multilevel ACDF has remained controversial. This report discusses a burst fracture seen as a complication in multilevel cervical stand-alone cage use.

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http://www.worldneurosurgery.org/article/S1878-8750(17)30778-7/fulltext?rss=yes

Preparing for the neurosurgery oral boards can be difficult, as neurosurgeons are typically juggling an increasingly busy clinical practice as well as academic and personal commitments. Without oral boards courses and high-yield review books, there would simply not be enough time for neurosurgeons to adequately prepare to achieve this milestone. Goodman's Neurosurgery Oral Board Review, edited by Allan D. Levi, provides an excellent primer not only for the Goodman Oral Board Course but also for the Oral Board Examination.

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Outcome After Subarachnoid Hemorrhage from Blood Blister–Like Aneurysm Rupture Depends on Age and Aneurysm Morphology  Voir?

Blood blister–like aneurysms (BBLA) are rare, challenging to treat, and prone to rerupture. We analyzed our results in relationship to type of BBLA and other prognostic factors.
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A Confirmed Case in the United Kingdom of Hirayama Disease in a Young White Male Presenting with Hand Weakness  Voir?

We present the first reported case of Hirayama disease in the United Kingdom. A literature review of Hirayama disease in the Western literature shows that this case is unique in being the first in the United Kingdom, constituting one of only a few cases in Europe with supporting magnetic resonance imaging and reported treatment outcome.

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Analysis of Patients with Myelopathy due to Benign Intradural Spinal Tumors with Concomitant Lumbar Degenerative Diseases Misdiagnosed and Erroneously Treated with Lumbar Surgery  Voir?

When a cervical or thoracic benign intradural spinal tumor (BIST) coexists with lumbar degenerative diseases (LDD), diagnosis can be difficult. Symptoms of BIST-myelopathy can be mistaken as being related to LDD. Worse, an unnecessary lumbar surgery could be performed. This study was conducted to analyze cases in which an erroneous lumbar surgery was undertaken in the wake of failure to identify BIST-associated myelopathy.

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Predictors of Shunt-dependent Hydrocephalus After Aneurysmal Subarachnoid Hemorrhage? A Systematic Review and Meta-Analysis  Voir?

Hydrocephalus is a well-recognized complication after aneurysmal subarachnoid hemorrhage (aSAH). This study aimed to identify predictors for shunt-dependent hydrocephalus (SDHC) after aSAH via a systematic review and meta-analysis.
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Clinical Efficacy and Its Prognostic Factor of Percutaneous Endoscopic Lumbar Annuloplasty and Nucleoplasty for the Treatment of Patients with Discogenic Low Back Pain  Voir?

The choice of appropriate treatment of discogenic low back pain (DLBP) frequently is difficult. This study sought to identify the clinical efficacy of percutaneous endoscopic lumbar annuloplasty and nucleoplasty (PELAN) to treat patients with DLBP and to investigate prognostic clinical or radiologic variables.

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Intraventricular Cavernomas of the Third Ventricle: Report of 2 Cases and a Systematic Review of the Literature  Voir?

Intraventricular cavernous malformations are relatively rare benign vascular malformations. Patients may be asymptomatic or present with headache, seizure, hemorrhage, or neurologic deficits. We report 2 cases of patients with cavernomas in the third ventricle and at the foramen of Monro. We also performed a systematic review of the literature to examine the clinical features and efficacy of the current standard of care for these lesions.

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Delayed Retroclival and Cervical Spinal Subdural Hematoma Complicated by Preexisting Chiari Malformation in Adult Trauma Patient  Voir?

Traumatic spinal subdural hematoma involving the retroclival region and upper cervical spine is a rare pathology. To our knowledge, there have only been 2 prior cases in an adult trauma patient. We describe a patient with preexisting Chiari 1 malformation, who recently sustained a unilateral type 1 occipital condyle fracture with associated disruption of the tectorial membrane and transverse ligament, which returned with a retroclival subdural hematoma extending down to C7, causing spinal cord compression and symptomatic obstructive hydrocephalus.

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Flow Diverters as Useful Adjunct to Traditional Endovascular Techniques in Treatment of Direct Carotid-Cavernous Fistulas  Voir?

Direct carotid-cavernous sinus fistulas (CCFs) are high-flow arteriovenous shunts that are typically the result of a severe head injury. The endovascular treatment of these lesions includes the use of detachable balloons, coils, liquid embolic agents, and covered stents. To minimize the chance of treatment failure and subsequent complications, endoluminal reconstruction using a flow-diverting stent may be added to the treatment construct.

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Management of Residual Tumor After Limited Subtotal Resection of Large Vestibular Schwannomas: Lessons Learned and Rationale for Specialized Care  Voir?

In an era where subtotal resection (STR) is increasingly used, we have encountered a growing number of patients referred to our institution with limited resection of large vestibular schwannomas (VSs), sometimes associated with grave complications. Our aim was to highlight lessons learned in the management of large VSs and provide a rationale for specialized care.

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Novel Oral Anticoagulants in Patients Undergoing Cranial Surgery  Voir?

The number of patients treated with novel oral anticoagulants (NOACs) is increasing. Despite growing clinical relevance, guidelines on the perioperative management of neurosurgical patients treated with NOACs are still lacking. The aim of this study was to analyze the occurrence of postoperative bleeding events and factors that might influence bleeding rates in these patients.

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Microsurgical Bypass Training Rat Model, Part 1: Technical Nuances of Exposure of the Aorta and Iliac Arteries  Voir?

Animal models using rodents are frequently used for practicing microvascular anastomosis—an essential technique in cerebrovascular surgery. However, safely and efficiently exposing rat's target vessels is technically difficult. Such difficulty may lead to excessive hemorrhage and shorten animal survival. This limits the ability to perform multiple anastomoses on a single animal and may increase the overall training time and costs. We report our model for microsurgical bypass training in rodents in 2 consecutive articles.

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Can We Make Simple In Situ Decompression of the Ulnar Nerve at the Elbow Still Easier?  Voir?

In situ decompression and transposition are equally effective in cubital tunnel syndrome treatment. Both are traditionally performed in the supine position.
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Face, Content, and Construct Validity of an Aneurysm Clipping Model Using Human Placenta  Voir?

Proficient open surgical treatment of cerebral aneurysms requires extensive training and practice. This study tested the validity of a human placenta aneurysm model for surgical simulation training of aneurysm clipping.
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http://www.worldneurosurgery.org/article/S1878-8750(17)30814-8/fulltext?rss=yes

Parts 1 and 2 of this handbook provide a comprehensive collection of concise chapters covering nearly all areas of neuroradiology, written by recognized leaders in the field. Each chapter contains up-to-date information, with well-chosen references for further study. Despite the diversity of topics, the organization is logical, starting with imaging methods and followed by pathology and common indications for brain and spine imaging, as well as pediatric neuroimaging. Chapters on neurointervention and high-resolution postmortem imaging contribute to the distinctive nature of this collection.

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Surgical Repair of Iatrogenic Transverse-Sigmoid Sinus Laceration with a Dural Flap During Skull Base Tumor Surgery: A Technical Case Report  Voir?

Injury to cerebral venous sinuses during craniotomy procedures can cause significant blood loss or venous air embolism, potentially leading to serious morbidity or mortality. When iatrogenic sinus injuries occur, it is essential to promptly obtain hemostasis and repair the sinus defect.
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The Healthcare Landscape: Are Doctors Agents of Change or Impediments to Change?  Voir?

Lead, follow, or get out of the way!—Lee Iacocca (former head of Chrysler Motors)—Sometimes give your services for nothing, calling to mind a previous benefaction or present satisfaction. And if there be an opportunity of serving one who is a stranger in financial straits, give full assistance to all such. For where there is love of man, there is also love of the art.—Hippocrates, Precepts, Chapter 6—

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A Cranial Trauma was the Cause of Death of Charles VIII of France (1470–1498)  Voir?

This article summarizes the reign, life and death, of Charles VIII of France. Also we intend to investigate current views on his cause of death, contradictions and opinions of his biographers. Poisoning, disease, and injury are the possible causes of his death but, according to the literature, cranial trauma was the most probable cause of death of the King Charles VIII of France.

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Endoscopic Supracerebellar Transtentorial Approach to Atrium of Lateral Ventricle: Preliminary Surgical and Optical Considerations  Voir?

We sought to report the operative techniques of the endoscopic supracerebellar transtentorial approach (ESTA) to the atrium of the lateral ventricle, especially focusing on the role of the endoscope and analyzing optically related issues.
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Clinical Application of Insertion Force Sensor System for Coil Embolization of Intracranial Aneurysms  Voir?

In endovascular embolization for intracranial aneurysms, it is important to properly control the coil insertion force. However, the force can only be subjectively detected by the subtle feedback experienced by neurointerventionists at their fingertips. The authors envisioned a system that would objectively sense and quantify that force. In this article, coil insertion force was measured in cases of intracranial aneurysm using this sensor, and its actual clinical application was investigated.

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Emergency Reoperations in Cranial Neurosurgery  Voir?

Complications after neurosurgical procedures that lead to reoperation are associated with poor outcome and economic costs. Therefore the aim of our study was to establish predictors of reoperation due to complications after cranial neurosurgery.
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Robotic Transnasal Endoscopic Skull Base Surgery: Systematic Review of the Literature and Report of a Novel Prototype for a Hybrid System (Brescia Endoscope Assistant Robotic Holder)  Voir?

Although robotics has already been applied to several surgical fields, available systems are not designed for endoscopic skull base surgery (ESBS). New conception prototypes have been recently described for ESBS. The aim of this study was to provide a systematic literature review of robotics for ESBS and describe a novel prototype developed at the University of Brescia.

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Biplanar Fluoroscopy-Guided Percutaneous Lead Implantation for Spinal Cord Stimulation: Technical Note  Voir?

The correct positioning of spinal cord stimulator leads is assessed radiographically during their percutaneous implantation for trial stimulation. Usually the C-arm is repositioned several times to allow imaging in different planes, which may extend the total duration of surgery. The study aimed to evaluate whether the concurrent intraoperative use of 2 C-arms could safely reduce the duration of surgery.

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Posterior Paramedian Approach to Ventrally Located Spinal Meningioma  Voir?

To approach a ventral spinal pathology, a lateral viewing angle is often required. However, lateral approaches to the spine are usually more technically demanding and require a certain amount of surgical expertise. In this report, we describe a simple and easy technique to obtain the lateral viewing angle to the ventral spinal pathology.

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Publication Metrics in Neurosurgery  Voir?

Evolutionary changes in health care over the past 2 decades have dramatically altered the landscape of academic medicine. Increasing clinical responsibilities, constant documentation reminders, repeated retraining requirements, complex quality metrics, and relative value unit productivity targets are the parameters by which physicians are measured today. These strictures are ever-present and have a great impact on salary and reimbursement and frequently influence physician comportment. For academic physicians, there is 1 more aspect to address or be cognizant of: scholarly efforts in the form of teaching, lectures, research, and publications.

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Spinal Arteriovenous Malformation Associated with Parkes Weber Syndrome: Report of Two Cases and Literature Review  Voir?

To present 2 cases of Parkes Weber syndrome (PWS) with spinal arteriovenous malformation (AVM) and discuss the radiologic features and clinical treatment with literature review.
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Newly Detected Cervical Spinal Dural Arteriovenous Fistula on Magnetic Resonance Angiography Causing Intracranial Subarachnoid Hemorrhage  Voir?

Although an asymptomatic spinal dural arteriovenous fistula (SDAVF) can sometimes be incidentally detected on magnetic resonance imaging (MRI), there are no previous reports showing the development of an SDAVF on MRI or magnetic resonance angiography (MRA).
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Endoscopic Removal of a Bullet That Migrated to the Third Ventricle Causing Hydrocephalus  Voir?

Hydrocephalus caused by an intraventricular bullet is a rare event. We report a case of endoscopic removal of an intraventricular bullet.
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Efficacy of Early Surgery for Neurological Improvement in Spinal Cord Injury without Radiographic Evidence of Trauma in the Elderly  Voir?

The optimal timing for surgery for patients with spinal cord injury without radiographic evidence of trauma (SCIWORET) remains unclear. This is especially true in the elderly, given that most studies are done with younger patients to avoid age-related comorbidities. We aimed to compare the efficacy of early (<24 hours postinjury) and late (>24 hours postinjury) surgery in patients with SCIWORET aged ≥65 years.

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Presence of a Malignant Tumor as a Novel Predictive Factor for Repeated Recurrences of Chronic Subdural Hematoma  Voir?

Various risk factors for recurrence of chronic subdural hematomas (CSDHs) have been reported, including alcohol addiction and diabetes mellitus. However, the significance of malignant tumors with respect to CSDH recurrence remains unclear.
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Giant Bicompartmental Cystic Tentorial Schwannoma Mimicking a Meningioma  Voir?

Intracranial schwannomas most commonly arise from the vestibulocochlear nerve and less frequently from trigeminal, facial, and hypoglossal nerves. Intracranial schwannomas unrelated to cranial nerves are very rare; only approximately 50 cases have been reported in the literature. Tentorial schwannoma (TS) is even rarer, with only 13 cases reported to date. We present a rare case of giant TS.

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Subventricular Zone Involvement Characterized by Diffusion Tensor Imaging in Glioblastoma  Voir?

Glioblastomas have a poor prognosis, possibly because of a subpopulation of therapy-resistant stem cells within the heterogeneous glioblastoma. Because the subventricular zone is the main source of neural stem cells, we aimed at characterizing the subventricular zone using diffusion tensor imaging (DTI) to show subventricular zone involvement in glioblastoma.

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Increased Levels of Soluble Cluster of Differentiation 40 Ligand, Matrix Metalloproteinase 9, and Matrix Metalloproteinase 2 Are Associated with Carotid Plaque Vulnerability in Patients with Ischemic Cerebrovascular Disease  Voir?

The objectives of this study were to examine the correlation between the level of serum inflammatory markers and the stability of carotid plaques in patients with ischemic cerebrovascular disease and to assess the ability of each inflammatory marker to identify vulnerable carotid plaques.
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Obese (Body Mass Index >30) Patients Have Greater Functional Improvement and Reach Equivalent Outcomes at 12 Months Following Decompression Surgery for Symptomatic Lumbar Stenosis  Voir?

To evaluate effect of obesity on 12-month functional outcomes after surgery for lumbar stenosis in adult patients.
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Surgical Outcome of Growth Hormone–Secreting Pituitary Adenoma with Empty Sella Using a New Classification  Voir?

To investigate outcomes and identified risk factors affecting cure and intraoperative cerebrospinal fluid leak after transsphenoidal surgery using a new classification for growth hormone–secreting pituitary adenoma associated with empty sella.
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Neurologic Outcome After Decompressive Craniectomy: Predictors of Outcome in Different Pathologic Conditions  Voir?

Decompressive craniectomy (DC) has been proposed as a lifesaving treatment in patients with elevated intracranial pressure, but its effectiveness on reaching a favorable neurologic outcome remains unclear. We identified predictors of outcome in a large, single-center cohort of patients undergoing DC for different pathologic conditions.

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The Effect of Morbid Obesity on Subarachnoid Hemorrhage Prognosis in the United States  Voir?

The association between obesity and nontraumatic subarachnoid hemorrhage (SAH) patient outcome is unclear. The aim of this study was to determine the impact of morbid obesity (body mass index ≥40 kg/m2) on nontraumatic SAH outcomes.
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Microsurgical Bypass Training Rat Model: Part 2–Anastomosis Configurations  Voir?

Mastery of microsurgical anastomosis is key to achieving good outcomes in cerebrovascular bypass procedures. Animal models (especially rodents) provide an optimal preclinical bypass training platform. However, the existing models for practicing different anastomosis configurations have several limitations.

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Remote Lesions of Synchronous Sacral and Cervical Dural Arteriovenous Fistulas: A Case Report  Voir?

Spinal dural arteriovenous fistula (DAVF) is a rare disease, and multiple concurrent lesions are extremely rare. Such multiple spinal DAVFs have similar outflow routes at neighboring levels. However, there have been no reported cases of remote lesions of multiple spinal DAVFs. The authors herein report a case of double synchronous cervical and sacral DAVFs.

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Occipital Nerve Stimulation for the Treatment of Refractory Occipital Neuralgia: A Case Series  Voir?

Occipital neuralgia is a chronic pain syndrome characterized by sharp, shooting pains in the distribution of the occipital nerves. Although relatively rare, it associated with extremely debilitating symptoms that drastically affect a patient's quality of life. Furthermore, it is extremely difficult to treat as the symptoms are refractory to traditional treatments, including pharmacologic and procedural interventions. A few previous case studies have established the use of a neurostimulation of the occipital nerves to treat occipital neuralgia.

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Medulloblastoma with Atypical Dynamic Imaging Changes: Case Report with Literature Review  Voir?

We analyzed a case of medulloblastoma with atypical dynamic imaging changes retrospectively to summarize the atypical magnetic resonance imaging (MRI) features of medulloblastoma by reviewing the literature.
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Effect of Aspirin in Postoperative Management of Adult Ischemic Moyamoya Disease  Voir?

Aspirin has been implicated in the postoperative management of moyamoya disease (MMD) in order to avoid bypass failure and decrease the incidence of subsequent stroke. However, its effect has not been completely determined yet.
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Long-Standing Isolated Autoimmune Hypothalamitis Diagnosed with Endoscopic Transventricular Biopsy  Voir?

Autoimmune hypothalamitis, which is among the causes of acquired central diabetes insipidus, has seldom been described in the literature. This condition is probably provoked by the production of anti-vasopressin-secreting cell antibodies and antihypothalamus antibodies and is often associated with pituitary or polyendocrine autoimmunity. Correct diagnosis and immediate treatment are essential to avoid the progression of the pathologic process.

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Subarachnoid Hemorrhage Because of Distal Superior Cerebellar Artery Dissection in Neurofibromatosis Type 1  Voir?

Neurofibromatosis type 1 (NF1) is a rare disease with an incidence of 1 in every 3000 births. Numerous studies have focused on the main function of NF1 as a tumor suppressor, whereas few have examined the cerebrovascular abnormalities observed in patients with NF1. It is worth noting that intracranial aneurysms are uncommon in this condition.

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“On the Spot”: The Use of Four-Dimensional Computed Tomography Angiography to Differentiate a True Spot Sign From a Distal Intracranial Aneurysm  Voir?

Spontaneous intracerebral hemorrhage may arise from underlying abnormalities, including aneurysms. Computed tomography angiography (CTA) is widely used for the detection of possible underlying causes, which is important because it may have immediate therapeutic consequences. In addition, CTA is used to detect the so-called spot sign, indicating active hemorrhage, which carries a worse prognosis. However, CTA is a snapshot in time. Four-dimensional (4D) CTA is a dynamic type of imaging and has emerged as a valuable imaging technique for different neurovascular disorders.

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Impact of Associated Nidal Lesions in Outcome of Brain Arteriovenous Malformations After Radiosurgery with or without Embolization  Voir?

Radiosurgery is a valuable option to treat arteriovenous malformations. There are correlations between some morphologic nidal features and final results, and the benefits of preradiosurgical embolization have not been well established thus far.
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Delayed Brainstem Hemorrhage Secondary to Mild Traumatic Head Injury: Report of Case with Good Recovery  Voir?

In clinical practice, secondary traumatic brainstem hemorrhage often develops during descending transtentorial herniation due to raised intracranial pressure, which is known as Duret hemorrhage.Although usually considered a fatal and irreversible event, in rare circumstances, victims of Duret hemorrhage could gain favorable outcomes.To our knowledge, secondary brainstem hemorrhage due to mild traumatic head injury without descending transtentorial herniation has never been reported. In this report, we present a case of delayed brainstem hemorrhage secondary to a relatively mild traumatic brain injury that experienced a rapid and favorable recovery.

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The Need for Clinical Practice Guidelines in Assessing and Managing Perioperative Neurologic Deficit: Results from a Survey of the AOSpine International Community  Voir?

There is no standardized approach to assess and manage perioperative neurologic deficit (PND) in patients undergoing spinal surgery. This survey aimed to evaluate the awareness and usage of clinical practice guidelines (CPGs) as well as investigate how surgeons performing spine surgeries feel about and manage PND and how they perceive the value of developing CPGs for the management of PND.

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Influence of Magnetic Resonance Imaging Features on Surgical Decision-Making in Degenerative Cervical Myelopathy: Results from a Global Survey of AOSpine International Members  Voir?

We conducted a survey to understand how specific pathologic features on magnetic resonance imaging (MRI) influence surgeons toward an anterior or posterior surgical approach in degenerative cervical myelopathy (DCM).
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http://www.worldneurosurgery.org/article/S1878-8750(17)30397-2/fulltext?rss=yes

In the fifth edition of The Prefrontal Cortex, Joaquín Fuster brings us an elegantly synthesized compendium describing the organizational principles of this most enigmatic region of the brain. Since the first edition was published 35 years ago, this text has become required reading of any scientist, clinician, or philosopher interested in cognition and its instantiation in the brain. With this edition, Dr. Fuster continues to propagate earlier insights from previous decades, while layering on new developments from physiology, imaging, and causal manipulation studies of the present day.

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Intracranial Hypotension Following Traumatic Brain Injury: A Diagnostic and Therapeutic Challenge  Voir?

Intracranial hypotension (IH) is a recognized cause of coma; however, the diagnosis is often challenging, especially in patients with superimposed traumatic brain injury.
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Results of Operative Treatment of Brachial Plexus Injury Resulting from Shoulder Dislocation: A Study with A Long-Term Follow-Up  Voir?

Injury to the infraclavicular brachial plexus is an uncommon but serious complication of shoulder dislocation. This work aims to determine the effectiveness of operative treatment in patients with this type of injury.
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A Case of Laterally Extended High-Positioned Chordoma Treated Using the High Cervical Retropharyngeal Approach  Voir?

Several surgical approaches for the treatment of pathologies of the craniovertebral junction (CVJ) and high cervical regions have been reported. For the best postoperative results, selection of a surgical route to treat such pathologies should be based on a complete understanding of the approach.
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Impact of Gradient Number and Voxel Size on Diffusion Tensor Imaging Tractography for Resective Brain Surgery  Voir?

To explore quantitatively and qualitatively how the number of gradient directions (NGD) and spatial resolution (SR) affect diffusion tensor imaging (DTI) tractography in patients planned for brain tumor surgery, using routine clinical magnetic resonance imaging protocols.
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Structural Allograft versus Autograft for Instrumented Atlantoaxial Fusions in Pediatric Patients: Radiologic and Clinical Outcomes in Series of 32 Patients  Voir?

Allograft with wire techniques showed a low fusion rate in pediatric atlantoaxial fusions (AAFs) in early studies. Using allograft in pediatric AAFs with screw/rod constructs has not been reported. Thus we compared the fusion rate and clinical outcomes in pediatric patients who underwent AAFs with screw/rod constructs using either a structural autograft or allograft.

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Long-Term Volume Reduction Effects of Endovascular Embolization for Intracranial Meningioma: Preliminary Experience of 5 Cases  Voir?

Preoperative endovascular embolization of intracranial meningiomas denatures the tumor tissue, reduces intraoperative blood loss, and facilitates surgical removal. However, as most meningiomas are surgically removed within a few days after embolization, the effect of long-term volume reduction of the tumor due to the endovascular embolization remains unknown.

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Four-Dimensional Phase Contrast Magnetic Resonance Imaging Protocol Optimization Using Patient-Specific 3-Dimensional Printed Replicas for In Vivo Imaging Before and After Flow Diverter Placement  Voir?

Hemodynamics in cerebral aneurysms are currently investigated toward clinical efficacy using nonstandardized computational simulation techniques. At the same time, flow patterns and velocities are accessible by 4-dimensional phase contrast magnetic resonance imaging (4D pcMRI). Complexity of protocol design and imaging duration has limited the use of this technique in clinical imaging. A new approach is presented to overcome these limitations.

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“Outside Support”: Curious Case of Duplicated Posterior Elements  Voir?

An 18-month-old male child was referred to our radiology department for imaging of a hard midline bony protuberance. On clinical examination the swelling was bony hard and not tender. Excoriations were seen on the overlying skin. Computed tomography and magnetic resonance imaging of the spine revealed heterotopic bone formation in the subcutaneous fat of the midline lumbar region (Figures 1 and 2). This well-formed corticated bone showed normal fatty marrow within it. The spinal cord was at its normal level for age without any tethering.

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Predictors of Outcomes in Fourth Ventricular Epidermoid Cysts: A Case Report and a Review of Literature  Voir?

To present an illustrative case of fourth ventricular epidermoid cyst and review the literature to identify predictors of surgical outcomes.
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Case of Familial Moyamoya Disease Presenting 10 Years After Initial Negative Magnetic Resonance Screening in Childhood  Voir?

Both genetic and environmental factors are considered to contribute to the onset of moyamoya disease, but the exact mechanism has not yet been clarified. Furthermore, the typical time course of progression to vessel occlusion has not been established, even in the genetically high-risk population.
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Role of Hemodynamic Forces in Unruptured Intracranial Aneurysms: An Overview of a Complex Scenario  Voir?

An understanding of the natural history of unruptured intracranial aneurysms (IAs) has always played a critical role in presurgical or endovascular planning, to avoid possibly fatal events. Size, shape, morphology, and location are known risk factors for rupture of an aneurysm, but morphologic parameters alone may not be sufficient to perform proper rupture risk stratification.

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Results of Early High-Flow Bypass and Trapping for Ruptured Blood Blister-Like Aneurysms of the Internal Carotid Artery  Voir?

The aim of this study is to clarify the efficacy and safety of early surgery using trapping of the affected internal carotid artery (ICA) and high-flow bypass between the second portion of the middle cerebral artery and cervical external carotid artery with radial artery graft for ruptured blood blister-like aneurysms (BBAs) arising from the anterior wall of the ICA.

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Was Cavum Septum Pellucidum the Cause of Intractable Seizure in a 17-Year-Old Boy with Wilson Disease?  Voir?

Cavum septum pellucidum (CSP), which is often found incidentally in a few populations, occasionally becomes symptomatic if enlarged significantly. Wilson disease (WD) is an uncommon autosomal recessive inborn defect in copper metabolism characterized by abnormal accumulation of copper in various tissues, particularly in the liver and the brain. Seizure disorder, although rare both in CSP and WD, may happen in a few patients with either of the conditions.

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Results of Atypical Hemifacial Spasm with Microvascular Decompression: 14 Case Reports and Literature Review  Voir?

Few studies have examined atypical hemifacial spasm (AHFS), and the mechanism of AHFS remains unclear. In this study, we examined the etiology, prognosis, and treatment of AHFS.
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Long-Term Functional Outcome of Symptomatic Unruptured Intracranial Aneurysms in an Interdisciplinary Treatment Concept  Voir?

In symptomatic unruptured intracranial aneurysms (UIAs), data on long-term functional outcome are sparse in the literature, even in the light of modern interdisciplinary treatment decisions. We therefore analyzed our in-house database for prognostic factors and long-term outcome of neurologic symptoms after microsurgical/endovascular treatment.

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Injury to the Lumbar Plexus and its Branches After Lateral Fusion Procedures: A Cadaver Study  Voir?

Neurologic deficits from lumbar plexus nerve injuries commonly occur in patients undergoing lateral approaches. However, it is not yet clear what types of injury occur, where anatomically they are located, or what mechanism causes them. We aimed to study 1) the topographic anatomy of lumbar plexus nerves and their injuries in human cadavers after lateral transpsoas approaches to the lumbar spine, 2) the structural morphology of those injuries, and 3) the topographic anatomy of the lumbar plexus throughout the mediolateral approach corridor.

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Irreversible Total Loss of Brain Function and Organ Donation in Patients with Aneurysmal Subarachnoid Hemorrhage  Voir?

Aneurysmal subarachnoid hemorrhage (aSAH) is a life-threatening disease with an often fatal clinical course leading to irreversible loss of brain function (ILBF) (i.e., brain death). The purpose of this study was to assess the prevalence and characteristics of patients with aSAH who became organ donors after diagnosis of ILBF.

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Use of Simple Neck Extension to Improve Guiding Catheter Accessibility in Tortuous Cervical Internal Carotid Artery for Endovascular Embolization of Intracranial Aneurysm: A Technical Note  Voir?

In endovascular embolization of intracranial aneurysms, a tortuous cervical internal carotid artery can limit guiding catheter access to a sufficiently high position. Although intermediate distal access catheters can go beyond the tortuous segment of internal carotid arteries, they may increase the risk of procedure-related complications, require significantly complex technical procedures, and limit the use of adjunctive techniques. Using simple neck extension alone, we successfully improved guiding catheter access in 2 patients.

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Dynamic Four-Dimensional Computed Tomography Angiography for Neurovascular Pathologies  Voir?

This article illustrates, summarizes, and reviews the multifaceted application of four-dimensional (4D) computed tomography angiography (CTA) in the characterization and diagnosis of various cerebrovascular and tumor-associated vascular pathologies through the presentation of clinical cases, including acute and chronic stroke, arteriovenous malformations, aneurysm, moyamoya disease, and hypervascularity associated with a tumor and its relationship to preoperative embolization. The technical nuances and limitations of the 4D-CTA technique are also discussed.

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Microsurgical Treatment of Colloid Cysts of the Third Ventricle  Voir?

This study analyzes the results of surgical treatment in 377 patients with colloid cysts (CCs) of the third ventricle who were treated at the Burdenko Neurosurgery Institute from 1981 to 2015. Operations were performed by a single surgeon (the first author of the article).
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Internal Maxillary Artery Bypass with Radial Artery Graft Treatment of Giant Intracranial Aneurysms  Voir?

Giant intracranial aneurysms (GIAs) can be approached via microsurgical and endovascular techniques. Use of flow diversion devices has yielded favorable outcomes, and indications for cerebral revascularization have dramatically decreased.
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Comparison of Operative Time with Conventional Fluoroscopy Versus Spinal Neuronavigation in Instrumented Spinal Tumor Surgery  Voir?

Spinal neuronavigation improves accuracy of pedicle screw placement but may increase operative time, and its use in oncologic operations remains relatively unstudied. We compared the use of two-dimensional (2D) fluoroscopy and three-dimensional (3D) spinal neuronavigation relative to operative time in instrumented oncology procedures.

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The Effect of Single-Level Disc Degeneration on Dynamic Response of the Whole Lumbar Spine to Vertical Vibration  Voir?

The objective of this study was to investigate the effect of single-level disc degeneration on dynamic response of the whole lumbar spine to vertical whole body vibration that is typically present when driving vehicles.
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A Case of Ecchordosis Physaliphora in the Prepontine Cistern: A Rare Entity in the Differential Diagnosis of an Epidermoid Cyst  Voir?

Ecchordosis physaliphora (EP) is a benign notochordal remnant that is usually asymptomatic. We report a case of a symptomatic large EP mimicking an epidermoid cyst.
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Patients' Perioperative Experience of Awake Deep-Brain Stimulation for Parkinson Disease  Voir?

Awake craniotomy for tumor resection and epilepsy surgery is a well-tolerated procedure. Qualitative data on patients' experience of awake deep-brain stimulation (DBS) are, however, lacking. We collected qualitative data on patients' experience of awake DBS with a view to identifying areas for improvement.

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Illumination in Spinal Surgery Depending on Different Approaches and Light Sources  Voir?

Sufficient visualization of the operating field is crucial for success in surgery and is important especially concerning minimally invasive and deep approaches in spine surgery.
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Sphenopterional Point: Strategic Point for Burr Role Placement in Frontotemporal Craniotomies  Voir?

Frontotemporal craniotomies are the most commonly performed neurosurgical approaches. We studied the external bony landmarks on the lateral surface of the skull to identify a “strategic” point where both the anterior and middle cranial fossae are exposed simultaneously during frontotemporal craniotomies through a single burr hole placed over the greater wing of the sphenoid bone (sphenopterional point).

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Radiation-Induced Malignant Peripheral Nerve Sheath Tumors: A Systematic Review  Voir?

Radiation-induced malignant peripheral nerve sheath tumors (MPNSTs) are an uncommon late risk of irradiation. We conducted the largest systematic review to date of individual patient data for patients with these tumors.
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One-Year Mortality of Patients with Chronic Kidney Disease After Spinal Cord Injury: A 14-Year Population-Based Study  Voir?

Chronic kidney disease (CKD) has become a global public health burden because of its increasing incidence, high risk of progression to end-stage renal disease (ESRD), and poor prognosis. We aimed to investigate the 1-year mortality of patients with spinal cord injury (SCI) with CKD and ESRD, and compare it with that of patients with SCI without CKD by reviewing a large Taiwanese population data set.

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Supracerebellar Infratentorial Paramedian Approach in Helsinki Neurosurgery: Cornerstones of a Safe and Effective Route to the Pineal Region  Voir?

The supracerebellar infratentorial (SCIT) paramedian approach in sitting position represents one of the most used surgical routes for dealing with pineal region lesions. The purpose of this study is to determine the cornerstones to perform this approach in a simple, safe, and effective way, so that it could be easily reproduced in other neurosurgical centers, particularly in those with modest resources.

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Which Approach Is Advantageous to Preventing Development of Adjacent Segment Disease? Comparative Analysis of 3 Different Lumbar Interbody Fusion Techniques (ALIF, LLIF, and PLIF) in L4-5 Spondylolisthesis  Voir?

The purpose of this study was to compare radiologic and clinical outcomes in patients with L4-5 lumbar spondylolisthesis who have undergone either instrumented anterior lumbar interbody fusion (ALIF), lateral lumbar interbody fusion (LLIF), or posterior lumbar interbody fusion (PLIF), especially with regard to the development of adjacent segment disease (ASD).

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Spontaneous Regression of a Hypoglossal Neurinoma: Case Report and Review of the Literature  Voir?

Hypoglossal neurinomas are very rare intracranial tumors. The management choices include surgery, as the gold standard, and radiosurgery or a combination of both. Little is known about this condition and the behavior of this tumor.
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Hereditary Multiple Cerebral Cavernous Malformations Associated with Wilson Disease and Multiple Lipomatosis  Voir?

We report on a patient with 2 Mendelian diseases—symptomatic multiple familial cerebral cavernous malformations (FCCMs) and Wilson disease. Genetic analysis revealed single nucleotide polymorphisms in genes CCM2 and CCM3, associated with cavernous malformations, and homozygote mutation in the ATP7B gene, responsible for Wilson disease. FCCMs were symptomatic in 3 generations. The patient also had multiple lipomatosis, which is suggested to be a familial syndrome.In recent years there has been an increasing amount of publications linking FCCMs with other pathology, predominantly with extracranial and intracranial mesenchymal anomalies.

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Successful Hybrid Neurovascular Surgery for a Ruptured Basilar Artery Dissecting Aneurysm in a Patient with Jeopardized Collateral Circulation Associated with Aortitis Syndrome  Voir?

Dissecting aneurysms of the basilar artery (BA) are rare lesions, and the management of them has been controversial and challenging. The treatment becomes much more difficult when the patient has a disorder such as aortitis syndrome, which makes cerebral arteries occluded and tortuous. We describe a case of a ruptured BA dissecting aneurysm associated with aortitis syndrome, successfully treated with hybrid neurovascular surgery.

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Brain Arteriovenous Malformations Located in Language Area: Surgical Outcomes and Risk Factors for Postoperative Language Deficits  Voir?

Case selection for surgical treatment of language-area brain arteriovenous malformations (L-BAVMs) remains difficult. This study aimed to determine the surgical outcomes and risk factors for postoperative language deficits (LDs) in patients with L-BAVMs.
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Ruptured Distal Anterior Choroidal Artery Aneurysm Treated with Superselective Provocative Testing and Coil Embolization  Voir?

Aneurysms of the anterior choroidal artery are uncommon, and distal anterior choroidal artery aneurysms are even rarer, with only 34 cases reported in the medical literature. These lesions have been most commonly reported in association with moyamoya disease or arteriovenous malformations. Most published experience with these aneurysms involves open surgical approaches. Reports of endovascular treatment have been in patients with lesions distal to the plexal point and have employed vessel occlusion with liquid embolic agents in preference to coil embolization.

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Association of Plasminogen Activator Inhibitor 1 (SERPINE1) Polymorphisms and Aneurysmal Subarachnoid Hemorrhage  Voir?

Genetic variations of the serine proteinase inhibitor family E member 1 (SERPINE1) gene, which encodes plasminogen activator inhibitor 1, correlate with serum levels of its product and are associated with thrombophilia and coronary atherosclerosis. Various SERPINE1 ;gene polymorphisms have been identified. However, only the functional 5G/4G polymorphism has been assessed in the context of aneurysmal subarachnoid hemorrhage (aSAH). We assessed associations of 6 SERPINE1 polymorphisms with the clinical sequelae of aSAH.

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An Affordable Microsurgical Training System for a Beginning Neurosurgeon: How to Realize the Self-Training Laboratory  Voir?

To provide detailed information about how to realize a self-training laboratory with cost-effective microsurgical instruments, especially pertinent for the novice trainee.
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Anterior Transthoracic Surgery with Motor Evoked Potential Monitoring for High-Risk Thoracic Disc Herniations: Technique and Results  Voir?

To present our experience with anterior transthoracic surgery for high-risk thoracic disc herniations (TDHs) using motor evoked potential monitoring (MEPm).
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Fluorescein Angiography in Intracranial Aneurysm Surgery: A Helpful Method to Evaluate the Security of Clipping and Observe Blood Flow  Voir?

In cerebral aneurysm surgery, various tools are used to evaluate blood flow, including Doppler ultrasonography, conventional cerebral angiography, and electrophysiological monitoring. Fluorescein and indocyanine green are widely used in vascular and central nervous system tumor neurosurgery; however, their routine utilization in aneurysmal surgery is uncommon, despite the fact that they allow direct visualization of blood flow after aneurysmal sac occlusion, enabling the observation of vessel permeability and the effectiveness of aneurysmal obliteration.

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Potential of New-Generation Double-Layer Micromesh Stent for Carotid Artery Stenting in Patients with Unstable Plaque: A Preliminary Result Using OFDI Analysis  Voir?

One disadvantage of carotid artery stenting (CAS) is a high incidence of distal embolism (DE) during or after the procedure. Patients with unstable plaque are considered at high risk for DE and plaque protrusion (PP) after stent placement, which can cause postprocedural ischemic complications. This study was conducted to compare the rate and size of PP between the CASPER stent, a new-generation double-layer micromesh stent, and conventional stents as assessed by optical frequency domain imaging (OFDI), and also to evaluate the efficacy of CAS with the CASPER stent in cases with unstable plaque.

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YouTube as a Source of Information on Neurosurgery  Voir?

The importance of videos in social media communications in the context of health care and neurosurgery is becoming increasingly recognized. However, there has not yet been a systematic analysis of these neurosurgery-related communications. Accordingly, this study was aimed at characterizing the online video content pertaining to neurosurgery.

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Cross-Modal Recruitment of Auditory and Orofacial Areas During Sign Language in a Deaf Subject  Voir?

Modern sign languages used by deaf people are fully expressive, natural human languages that are perceived visually and produced manually. The literature contains little data concerning human brain organization in conditions of deficient sensory information such as deafness.
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Primary Spinal Intramedullary Neurocysticercosis: A Report of 3 Cases  Voir?

We describe a series of 3 cases of the rare intramedullary form of primary spinal neurocysticercosis. The cases were seen in varied age groups and showed different profiles at presentation. All the cases were thoroughly evaluated clinically and radiologically. Serologic tests were not conducted. In all cases, magnetic resonance imaging showed a large intramedullary lesion in the thoracic spinal cord consisting of a cystic lesion with a well-defined intramural nodule. One case was managed with steroids and cysticidal therapy, a second case was managed with steroids and surgery (2 emergency procedures), while the third case was managed without any medical or surgical intervention, as the patient was unwilling for either.

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Prognostic Factors for Recovery of Patients After Surgery for Thoracic Spinal Tuberculosis  Voir?

Thoracic spinal tuberculosis (TST) is a dangerous disease. Besides antituberculosis chemotherapy, surgery is also necessary for treating TST. To date, no study has focused on the prognostic factors for recovery of patients after surgery for TST.
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Prognostic Value of Preoperative Nurick Grade and Time with Symptoms in Patients with Cervical Myelopathy and Gait Impairment  Voir?

To investigate the prognostic value of preoperative Nurick grade and time with symptoms for gait improvement and recovery in patients with ataxia secondary to cervical myelopathy.
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High Expression of Glypican-1 Predicts Dissemination and Poor Prognosis in Glioblastomas  Voir?

Glioblastoma (GBM) relapses locally or in a disseminated pattern and is highly resistant to chemoradiotherapy. Although dissemination is associated with poor prognosis for patients with GBM, the clinicopathologic factors that promote dissemination have not been elucidated. Glypican-1 (GPC-1) is a heparin sulfate proteoglycan that is attached to the extracytoplasmic surface of the cell membrane and regulates cell motility. The aim of this study was to determine whether GPC-1 expression correlated with GBM dissemination and patient prognosis.

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Autostereoscopic Three-Dimensional Neuronavigation to the Sella: Technical Note  Voir?

A drawback of conventional neuronavigation is the necessity of focusing on two-dimensional images in 3 planes at the same time to determine one's position in the operating field. A solution would be to merge the images into a single three-dimensional (3D) image that mirrors the actual anatomy. The introduction of holographic glassless 3D monitors paved the way to 3D navigation. We present our experience with 3D neuronavigation as exemplified by navigation to and within the sella.

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Intraoperative Scoring System to Predict Postoperative Remission in Endoscopic Endonasal Transsphenoidal Surgery for Growth Hormone–Secreting Pituitary Adenomas  Voir?

To determine the predictive factors for endocrinological remission of patients with growth hormone (GH)-secreting pituitary adenomas.
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Minimally Invasive Surgery for Patients with Hypertensive Intracerebral Hemorrhage with Large Hematoma Volume: A Retrospective Study  Voir?

Therapeutic efficacy of patients with hypertensive intracerebral hemorrhage (HICH) with large hematoma volume is poor. This study aimed to explore the efficacy of minimally invasive surgery for patients with HICH with large hematoma volume.
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Classification of Meningiomas Based on Their Surgical Removal, World Health Organization Grade, and Cytogenetic Profile: A Treatment Algorithm  Voir?

Meningiomas are the most common primary intracranial tumor, but the lack of prospective randomized trials has led to different guidelines for their treatment. We proposed a classification of meningiomas that considers surgical removal, histology, and cytogenetic profile, based on a literature review of these 3 criteria. The classification can be used to guide adjuvant treatment and follow-up.

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The Histological Effects of Ozone Therapy on Sciatic Nerve Crush Injury in Rats  Voir?

Peripheral nerve injury is a common, important problem that lacks a definitive, effective treatment. It can cause neurologic deficits ranging from paresthesia to paralysis. This study evaluated the effect of ozone therapy on sciatic nerve crush injury in rats.
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Predatory Publishing and Academic Integrity  Voir?

Although the increase in article retraction has been discussed extensively within various academic circles, there has been little-to-no investigation regarding how this trend has specifically affected the field of neurosurgery. In “Retraction of Neurosurgical Publications: A Systematic Review,” Wang et al. address in clear, quantifiable terms, how this issue has manifested itself within our discipline. Although their findings and recommendations could certainly assist neurosurgical departments in strengthening their scholarly output, it might also be prudent to explore some of the observations and tools other disciplines have reported regarding topics pertinent to article retraction.

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Conservative and Surgical Treatment of Patients with Pineal Cysts: Prospective Case Series of 110 Patients  Voir?

A pineal cyst is a relatively common benign condition of the pineal gland. The clinical management of patients with a pineal cyst remains controversial, especially when patients present with nonspecific symptoms.
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Repair of V2 Vertebral Artery Injuries Sustained During Anterior Cervical Diskectomy  Voir?

The V2 segment of the vertebral artery (VA) typically runs through the transverse foramen of C2-C6. V2 injury may occur during anterior approaches to the cervical spine and can cause significant morbidity. We describe landmarks and microsurgical V2 repair techniques through the standard anterolateral cervical diskectomy approach.

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Outcomes Following Exploratory Burr Holes for Traumatic Brain Injury in a Resource Poor Setting  Voir?

Traumatic brain injury (TBI) is a leading cause of death and disability worldwide. The incidence of TBI in low- and middle-income countries (LMICs) is disproportionately high, with an associated increased risk of mortality from TBI relative to high-income countries. Although computed tomography is the diagnostic method of choice, this is often unavailable in LMICs. Exploratory burr holes may provide a suitable choice for diagnosis and treatment of TBI.

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Functional Connectivity in Frontoparietal Network: Indicator of Preoperative Cognitive Function and Cognitive Outcome Following Surgery in Patients with Glioma  Voir?

Patients with diffuse glioma are known to have impaired cognitive functions preoperatively. However, the mechanism of these cognitive deficits remains unclear. Resting-state functional connectivity in the frontoparietal network (FPN) is associated with cognitive performance in healthy subjects. For this reason, it was hypothesized that functional connectivity of the FPN would be related to cognitive functioning in patients with glioma. To assess this relationship, preoperative cognitive status was correlated to patient-specific connectivity within the FPN.

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Assessment of Cost Drivers in Transsphenoidal Approaches for Resection of Pituitary Tumors Using the Value-Driven Outcome Database  Voir?

Reducing health care costs while improving quality of care has become imperative in neurosurgical care. The Value-Driven Outcome database at the University of Utah identifies cost drivers and tracks changes over time.
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Intraprocedural Rupture of Unruptured Cerebral Aneurysms During Coil Embolization: A Single-Center Experience  Voir?

Incidence of intraprocedural rupture (IPR) during endovascular coiling is reported to be 2%–5%. We reviewed a single-center experience of IPR during coil embolization of unruptured intracranial aneurysms.
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Brain Arteriovenous Malformations Located in Premotor Cortex: Surgical Outcomes and Risk Factors for Postoperative Neurologic Deficits  Voir?

The premotor cortex (PMC) is known to have a dual role in movement and language processing. Nevertheless, surgical outcomes of brain arteriovenous malformations located in PMC (PMC-BAVMs) have not been well defined. The aim of this study was to determine surgical outcomes and risk factors for neurologic deficits (NDs) after surgery in patients with PMC-BAVMs.

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A retrospective study of clinical outcomes after endovascular treatment in acute ischemic stroke patients with complete anterior circulation infarction (TACI) in the absence of multimodal CT  Voir?

To analyze the positive predictive value of large artery occlusion and clinical prognosis in acute ischemic stroke patients with total anterior circulation infarct (TACI) who underwent endovascular treatment in the absence of multimodal CT angiography (CTA)/ CT perfusion (CTP).
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Factors Affecting the Visual Outcome of Pituitary Adenoma Patients Treated with Endoscopic Transsphenoidal Surgery  Voir?

To evaluate visual acuity (VA) and visual fields (VF) quantitatively before and after endoscopic transsphenoidal surgery (ETS), with special attention to prognostic factors such as the pituitary adenoma (PA) suprasellar extension (SSE), volume and the patients' age.
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Requirements for a Stable Long-Term Result in Surgical Reduction of Vertebral Fragility Fractures  Voir?

Osteoporotic vertebral fractures are one of the major health problems in the world. Minimally invasive surgical treatment has great advantages compared with conservative treatment in treating these fractures, because it eliminates pain and functional disability. The percutaneous intravertebral expandable titanium device SpineJack (Vexim SA, Balma, France) is beneficial compared with other kyphoplasty devices, showing results that are maintained over time and a reduction in complications. However, controversy exists about the minimum amount of cement that should be used to achieve long-term restoration and which is essential to minimize complications.

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Inside Vietnam's Largest Neurosurgery Department  Voir?

Cho Ray Hospital is the premier tertiary care center in Ho Chi Minh City, Vietnam's most populous city. The neurosurgical department was founded in 1958 and is currently one of the busiest in the world. Last year the department was responsible for more than 10,000 neurosurgical operations, excluding neuroendovascular cases. Most of the elective cases are craniotomies for complex lesions such as aneurysms, arteriovenous malformations, skull base tumors, gliomas, and meningiomas. Although the neurosurgeons within the department are technically gifted, doing more with less predominates as the mantra at Cho Ray Hospital.

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Intracranial Aneurysm in Patients with Sickle Cell Disease: A Systematic Review  Voir?

Intracranial aneurysm in patients with sickle cell disease is rare, but with an increased incidence in the recent years. This type of intracranial aneurysm possesses distinctive characteristics, and it has been the subject of case reports and series.
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Intraspinal Pressure Monitoring and Extensive Duroplasty in the Acute Phase of Traumatic Spinal Cord Injury: A Systematic Review  Voir?

The prognosis in cervical spinal cord injury is poor, and surgical and neurointensive care management need further improvement. Monitoring of the intraspinal pressure (ISP) at an early stage after traumatic spinal cord injury (tSCI) is useful clinically.
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The Timed Up and Go Test as a Diagnostic Criterion in Normal Pressure Hydrocephalus  Voir?

Normal-pressure hydrocephalus (NPH) is a disease characterized by gait disturbance, urinary incontinence, and dementia. Our objectives were to define an average value of the test for the population, check the specificity and test sensitivity as evaluation criteria and diagnostic testing, and correlate with other already used more frequently.

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Clinical and Radiologic Outcomes After Fenestration and Partial Wall Excision of Idiopathic Intradural Spinal Arachnoid Cysts Presenting with Myelopathy  Voir?

Intradural spinal arachnoid cysts (ISACs) with associated neurologic deficits are encountered infrequently. Various management strategies have been proposed with minimal data on comparative outcomes.
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Effects of Dexamethasone in the Treatment of Recurrent Chronic Subdural Hematoma  Voir?

Recurrent chronic subdural hematoma (CSDH) is not rare. Some studies have demonstrated the role of dexamethasone in the medical management of chronic subdural hematoma. However, no systematic study in the treatment of recurrent CSDH has been published. The aim of our study is to evaluate the efficacy and safety of dexamethasone in patients with recurrent CSDH.

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Surgical Evacuation of Spontaneous Supratentorial Lobar Intracerebral Hemorrhage: Comparison of Safety and Efficacy of Stereotactic Aspiration, Endoscopic Surgery, and Craniotomy  Voir?

The safety and efficacy of craniotomy, endoscopic surgery, and stereotactic aspiration for surgical evacuation of spontaneous supratentorial lobar intracerebral hemorrhage (ICH) is yet uncertain. The present study analyzed the clinical and radiographic data from 99 patients with spontaneous supratentorial lobar ICH, retrospectively, to address this issue.

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Reconstruction of Thoracic Spine Using a Personalized 3D-Printed Vertebral Body in Adolescent with T9 Primary Bone Tumor  Voir?

Neurosurgery and spine surgery have the potential to benefit from the use of 3-dimensional printing (3DP) technology due to complex anatomic considerations and the delicate nature of surrounding structures. We report a procedure that uses a 3D-printed titanium T9 vertebral body implant post T9 vertebrectomy for a primary bone tumor.

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Outcome Evaluation of Patients with Limited Brain Metastasis From Malignant Melanoma, Treated with Surgery, Radiation Therapy, and Targeted Therapy  Voir?

The incidence of brain metastases from melanoma is increasing. Several effective treatment options are now available but what can be considered the optimal therapeutic strategy is not yet defined. We evaluated the outcome of patients with brain metastatic melanoma in terms of local control rate, brain distant progression, and overall survival.

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Two-Dimensional High Definition Versus Three-Dimensional Endoscopy in Endonasal Skull Base Surgery: A Comparative Preclinical Study  Voir?

Three-dimensional (3D) endoscopy has been recently introduced in endonasal skull base surgery. Only a relatively limited number of studies have compared it to 2-dimensional, high definition technology. The objective was to compare, in a preclinical setting for endonasal endoscopic surgery, the surgical maneuverability of 2-dimensional, high definition and 3D endoscopy.

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The Neurosurgery Match: A Bibliometric Analysis of 206 First-Year Residents  Voir?

An important component of the residency application for neurosurgery is research experience and the subsequent number of produced publications. Bibliometrics research has been developed to establish quantitative methods for the standardization of publishing impactful research. This study aims to quantify the research productivity of medical students who successfully matriculated into a Neurosurgery residency program.

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Pipeline Embolization Device in Treatment of 50 Unruptured Large and Giant Aneurysms  Voir?

Treatment of large (≥20 mm) and giant (≥25 mm) intracranial aneurysms is challenging and can be associated with a high rate of morbidity and mortality. The Pipeline Embolization Device (PED) has been used effectively for the treatment of intracranial aneurysms achieving a high rate of complete occlusion. However, its safety and efficacy in treatment of large and giant aneurysms has not been evaluated fully.

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Safety of Percutaneous Dilatational Tracheostomy in Patients with Acute Brain Injury and Reduced PaO2/FiO2 Ratio—Retrospective Analysis of 54 Patients  Voir?

Percutaneous dilatational tracheostomy (PDT) is a commonly performed method in neurocritical care, and its safety has been proven in numerous studies. Nevertheless, data regarding the application in patients with acute brain injury and poor respiratory function are poor. The purpose of this study was to evaluate the incidence of hypoxemia and hypercapnia during PDT in those patients.

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Safety and Efficacy of Antibacterial Prophylaxis After Craniotomy: A Decision Model Analysis  Voir?

Antibiotic prophylaxis has revolutionized the safety of neurosurgical procedures in the last century. Today, the clinician's drug of choice before surgery often is based on the antibiotic's resistance profile and drug-induced complications.
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Preserving the Facial Nerve During Orbitozygomatic Craniotomy: Surgical Anatomy Assessment and Stepwise Illustration  Voir?

Surgical safety and efficiency during an orbitozygomatic (OZ) osteotomy rely on thorough knowledge of the surgical anatomy of the facial nerve. Although the anatomy of the facial nerve and its relation to the pterional craniotomy are described, a thorough assessment of facial nerve preservation techniques during the OZ approach and its variations is lacking. We assessed the surgical anatomy of the facial nerve related to the OZ approach and provided a thorough stepwise description on how to preserve it.

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Evaluation of Screw Placement Accuracy in Circumferential Lumbar Arthrodesis Using Robotic Assistance and Intraoperative Flat-Panel Computed Tomography  Voir?

Neuronavigation has become a common means of placing pedicle screws in vertebral arthrodesis, because it reduces the incidence of complications related to poor screw positioning.
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Anterior Column Realignment has Similar Results to Pedicle Subtraction Osteotomy in Treating Adults with Sagittal Plane Deformity  Voir?

Anterior column realignment (ACR) is a minimally invasive surgical technique used for the correction of adult sagittal plane deformity. ACR is performed via a minimally invasive lateral transpsoas approach with anterior longitudinal ligament release and hyperlordotic cage placement. The objective of this study was to compare radiographic outcomes and complications in patients treated by ACR or Pedicle subtraction osteotomy (PSO).

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Risk Factors for Ventriculoperitoneal Shunt Dependency in Patients with Spontaneous Cerebellar Hemorrhage  Voir?

Hydrocephalus is a common complication after spontaneous cerebellar hemorrhage (CH). This study focused on predicting ventriculoperitorneal (VP) shunt dependency in patients with spontaneous CH.
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Potential for Intrathecal Baclofen in Treatment of Essential Tremor  Voir?

Essential tremor (ET) is the most common movement disorder of adults, affecting an estimated 7 million Americans. Symptoms of ET range from slightly noticeable to debilitating, with 1 cohort study finding 15% of patients were forced into early retirement. Additionally, depression has also been correlated with the severity of disability of ET. Treatment options include propranolol and primidone. Current treatment options are not very effective, with more than half (56.3%) of patients discontinuing medications because of no changes in symptoms.

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Respiratory and Swallowing Outcomes Based on Aneurysm Location in 360 Patients with Subarachnoid Hemorrhage  Voir?

Aneurysmal subarachnoid hemorrhage (aSAH) may result in abnormal respiratory and swallowing function. We analyzed factors that may influence long-term respiratory and swallowing function in aSAH patients and compared patients with anterior and posterior aneurysm locations.
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Vitom-3D for Exoscopic Neurosurgery: Initial Experience in Cranial and Spinal Procedures  Voir?

The authors describe the application of a new exoscope that offers 3-dimensional (3D) visualization in cranial and spinal neurosurgery in detail.
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Endoscopic Third Ventriculostomy for the Treatment of Hydrocephalus in a Pediatric Population with Myelomeningocele  Voir?

Hydrocephalus develops in up to 90% of patients born with myelomeningocele. Although endoscopic third ventriculostomy (ETV) is currently considered the preferred treatment for obstructive hydrocephalus, its results have been inconsistent in patients with myelomeningocele. This study focuses on clinical and radiologic outcomes of ETV in children with hydrocephalus related to myelomeningocele.

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Chronic Subdural Hematoma in Women  Voir?

Sex differences in various diseases recently have been recognized as an important factor in the approach to more efficient preventive and therapeutic medicine. We clarified sex differences in the clinical characteristics of chronic subdural hematoma (CSDH) by comparing men and women with CSDH, as there is a well-known male predominance in the prevalence of CSDH.

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Comparison of Stent-Assisted Coil Embolization and the Pipeline Embolization Device for Endovascular Treatment of Ophthalmic Segment Aneurysms: A Multicenter Cohort Study  Voir?

Stent-assisted coil embolization and flow diversion with the Pipeline embolization device (PED) are both effective endovascular treatment options for ophthalmic segment aneurysms (OSAs) of the internal carotid artery. Here we present a large comparative cohort study.
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A Meta-Analysis on the Clinical Significance of Redundant Nerve Roots in Symptomatic Lumbar Spinal Stenosis  Voir?

Symptomatic lumbar spinal stenosis (LSS), which leads to severe socioeconomic consequences and places a heavy burden on global healthcare system, is a relatively frequent spine disorder. Redundant nerve roots (RNRs) are a relatively common finding in which slender, serpiginous, or tortuous nerve roots are found in the subarachnoid space of the lumbar spine. Previous studies that evaluated the prognostic assessment of RNRs in patients with symptomatic LSS are composed of doubtful results. Therefore, the clinical significance of RNRs in symptomatic LSS is still uncertain.

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Severe Traumatic Brain Injury at a Tertiary Referral Center in Tanzania: Epidemiology and Adherence to Brain Trauma Foundation Guidelines  Voir?

Severe traumatic brain injury (TBI) is a major cause of death and disability worldwide. Prospective TBI data from sub-Saharan Africa are sparse. This study examines epidemiology and explores management of patients with severe TBI and adherence to Brain Trauma Foundation Guidelines at a tertiary care referral hospital in Tanzania.

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Stemness Marker Detection in the Periphery of Glioblastoma and Ability of Glioblastoma to Generate Glioma Stem Cells: Clinical Correlations  Voir?

Recent studies suggested glioma stem cells (GSCs) are key contributors to therapeutic resistance of glioblastoma multiforme (GBM) and are responsible for GBM recurrence.
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Risk Factors for Surgical Results of Hirayama Disease: A Retrospective Analysis of a Large Cohort  Voir?

To explore risk factors affecting surgical results of Hirayama disease.
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Primary Pituitary Fibrosarcoma with Previous Adenoma  Voir?

Pituitary sarcomas are rare clinical entities most often encountered as secondary neoplasms representing late sequelae of radiation therapy to the sellar region. Primary pituitary fibrosarcomas (PPFS), in contrast, are exceptionally rare tumors with very few cases described in the literature thus far. Herein, we present a case of PFFS and describe it in the context of the existing literature.

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Incidence and Risk Factors of Postoperative Adjacent Segment Degeneration Following Anterior Decompression and Instrumented Fusion for Degenerative Disorders of the Cervical Spine  Voir?

To explore incidence and risk factors of postoperative adjacent segment degeneration (ASD) following anterior decompression and instrumented fusion for degenerative disorders of the cervical spine.
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The Impact of Kidney Disease on Acute Tubular Necrosis and Surgical Site Infection After Lumbar Fusion  Voir?

Kidney disease in spine surgery can be associated with serious complications.
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A Novel Approach for Percutaneous Vertebroplasty Based on Preoperative Computed Tomography–Based Three-Dimensional Model Design  Voir?

To describe a new technique for the efficient use of preoperative planning based on preoperative computed tomography–based three-dimensional (3D) model design for percutaneous vertebroplasty (PVP) in a patient with osteoporotic vertebral compression fracture.
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Analysis of Factors Related to Hypopituitarism in Patients with Nonsellar Intracranial Tumor  Voir?

Previous studies have suggested that postoperative hypopituitarism in patients with nonsellar intracranial tumors is caused by traumatic surgery. However, with development of minimally invasive and precise neurosurgical techniques, the degree of injury to brain tissue has been reduced significantly, especially for parenchymal tumors. Therefore, understanding preexisting hypopituitarism and related risk factors can improve perioperative management for patients with nonsellar intracranial tumors.

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Hypertonic Saline for Increased Intracranial Pressure After Aneurysmal Subarachnoid Hemorrhage: A Systematic Review  Voir?

The use of hyperosmolar agents, such as mannitol or hypertonic saline (HTS), to control high intracranial pressure (ICP) in patients with traumatic brain injury has been well studied. However, the role of HTS in the management of aneurysmal subarachnoid hemorrhage (aSAH)-associated increased ICP is still unclear.

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Endoscopic Endonasal Resection of a Mixed Lesion of Gangliocytoma and Nonfunctioning Pituitary Adenoma  Voir?

The coexistence of a gangliocytoma and a pituitary adenoma is a rare event that has been reported in only case reports. The knowledge of its diagnosis and treatment is extremely limited.
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Volume-Outcome Relationship After 1 and 2 Level Anterior Cervical Discectomy and Fusion  Voir?

To investigate the effects of surgeon volume on inpatient morbidity after 1- and 2-level anterior cervical discectomy and fusion (ACDF).
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Impact of Elderly Age on Complications and Clinical Outcomes Following Anterior Lumbar Interbody Fusion Surgery  Voir?

Anterior lumbar interbody fusion (ALIF) is a surgical technique used to treat patients with a variety of lumbar pathologies. Identification of risk factors leading to complication following ALIF surgery may allow surgeons to better judge candidacy and optimize care for high-risk patients.
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Intraoperative Mapping and Monitoring of the Pyramidal Tract Using Endoscopic Depth Electrodes  Voir?

To evaluate motor function during neuroendoscopic resectioning of deep-seated brain tumors using endoscopically guided depth electrodes.
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“Asleep” Deep Brain Stimulation Surgery: A Critical Review of the Literature  Voir?

Although performing deep brain stimulation (DBS) with the patient under general anesthesia without microelectrode recording (MER) or intraoperative test stimulation (ITS) for movement disorders (“asleep” DBS) has become increasingly popular, its feasibility is based on the untested assumption that stereotactic accuracy correlates with positive clinical outcomes. To investigate outcomes after asleep DBS without MER or neurophysiological testing, we reviewed the medical literature on the topic.

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Predictive Factors of Postoperative Seizure for Pediatric Patients with Unruptured Arteriovenous Malformations  Voir?

Seizure is the second-most common presentation in patients with arteriovenous malformations (AVMs) and superimposes a significant burden on pediatric patients. Postoperative seizure risk in unruptured AVMs is underreported in the pediatric AVM literature. We aimed to characterize and identify predictive factors for postoperative seizures in this study.

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Complicated Mild Traumatic Brain Injury and the Need for Imaging Surveillance  Voir?

To evaluate the need for repeat head computed tomography (CT) in patients with complicated mild traumatic brain injury (TBI) determined nonoperative after the first head CT.
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Customized Polymethylmethacrylate Cranioplasty Implants Using 3-Dimensional Printed Polylactic Acid Molds: Technical Note with 2 Illustrative Cases  Voir?

Prefabricated customized cranioplasty implants are anatomically more accurate than manually shaped acrylic implants but remain costly. The authors describe a new cost-effective technique of producing customized polymethylmethacrylate (PMMA) cranioplasty implants with the use of prefabricated 3-dimensional (3D) printed molds.

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What Factors Determine Treatment Outcome in Aneurysmal Subarachnoid Hemorrhage in the Modern Era? A Post Hoc STASH Analysis  Voir?

The management of aneurysmal subarachnoid hemorrhage (aSAH) has changed dramatically in the last few decades with the publication of a few major studies, including ISAT (International Subarachnoid Aneurysm Trial, the International Cooperative Study on the Timing of Aneurysm Surgery Study). The aim of this study is to analyze the outcome of patients with aSAH based on a contemporary series, identify the risk factors for poor outcome, and focus on patients with good-grade aSAH (to match the ISAT cohort).

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Radiolucent Carbon Fiber–Reinforced Pedicle Screws for Treatment of Spinal Tumors: Advantages for Radiation Planning and Follow-Up Imaging  Voir?

Surgical treatment of spinal tumors regularly includes spinal instrumentation with pedicle screws. Most modern pedicle screws are made of titanium alloy, which is associated with artifacts on postoperative imaging such as computed tomography and/or magnetic resonance imaging. These artifacts hamper radiation treatment planning and execution and follow-up imaging. Recently, carbon fiber–reinforced polyetheretherketone (CFRP) implants became available for posterior instrumentation with the aim to reduce imaging artifacts by implants.

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Management of Glioblastoma Multiforme in Elderly Patients: A Review of the Literature  Voir?

Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor in adults, occurs most commonly in individuals older than 65 years of age, and is universally fatal. Increasing age compounds the poor prognosis of GBM, as elderly patients have markedly worse outcomes than younger patients. However, many of the studies previously investigating optimal treatment regimens exclude patients older than the age of 65 years and thus may not represent the best approaches to ensuring prolonged survival with preserved quality of life.

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Stereotactic radiosurgery for dural carotid cavernous sinus fistulas  Voir?

We reviewed our 7-year experience to assess the efficacy of stereotactic radiosurgery (SRS) for dural carotid cavernous fistulas (DCCFs). We analyzed the clinical outcome, complications and angiographic results.
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Is There a Formula for Residency Selection of Future Academic Neurosurgeons?  Voir?

In this enlightening article, Chaichana et al.1 set out to evaluate the impact of published research before and during residency in eventually attaining neurosurgery faculty positions in academic hospitals. To arrive at their findings, the authors collected alumni information from 65 neurosurgery residency websites (60% of programs), and analyzed 949 graduates from programs between 2005 and 2015 for factors associated with an academic career, including information on publications, citations, and H-index (i.e., the productivity and impact of the citation).

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Therapeutic Options for Recurrent High-Grade Gliomas: A Perspective Statement  Voir?

High-grade gliomas (HGGs), comprising World Health Organization (WHO) grade III and IV tumors, are associated with dismal prognosis regarding progression-free survival (PFS) and overall survival (OS). According to current data, the expected median OS for patients with newly diagnosed anaplastic astrocytomas (WHO III) and glioblastoma multiforme (GBM; WHO IV) still remains in the range of only 24–36 and 12–15 months, respectively.1,2 All patients suffering from HGGs will eventually develop tumor recurrences and succumb to their disease.

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DNA Methylation Regulates Gene Expression in Intracranial Aneurysms  Voir?

Different gene expression profiles are observed in intracranial aneurysm tissues. Understanding these genes and what regulates their expression will provide insight into the pathogenesis of intracranial aneurysms. We investigated whether differences in DNA methylation regulate gene expression in intracranial aneurysms.

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Reconstruction of Cranial Vault Defect with Polyetheretherketone Implants  Voir?

Reconstruction of a cranial vault defect is a frequent challenge in neurosurgery. Polyetheretherketone (PEEK) is used in many types of prostheses and has been employed for 10 years in our institution (University Hospital of Toulouse, France). The objectives of this study are to describe the benefits and drawbacks of reconstructing the cranial vault defect with a PEEK prosthesis.

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Microsurgical Resection After Failed Gamma Knife Radiosurgery of Papillary Tumor of the Pineal Gland  Voir?

Primary papillary tumors of the pineal region are rare entities with distinct histopathologic characteristics. The most common surgical approaches include the supracerebellar infratentorial corridor or the occipital interhemispheric approach. Gamma knife radiosurgery (GKRS) is an acceptable treatment modality for parenchymal tumors of the pineal gland and often is used as a primary treatment modality for asymptomatic and indolent lesions and as an adjunct to surgical resection. In this presentation, we describe the surgical nuances of posterior interhemispheric approach in an elderly man with a previously failed empirical GKRS.

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Endovascular Treatment of Complex Distal Posterior Cerebral Artery Aneurysms with the Pipeline Embolization Device  Voir?

To assess the safety and efficacy of the Pipeline Embolization Device (PED) for endovascular treatment of complex, distal posterior cerebral artery (PCA) aneurysms.
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Awake High-Flow Extracranial to Intracranial Bypass for Complex Cerebral Aneurysms: Institutional Clinical Trial Results  Voir?

Assess the potential added benefit to patient outcomes of “awake” neurological testing when compared with standard neurophysiologic testing performed under general endotracheal anesthesia.
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Supraorbital Versus Endoscopic Endonasal Approaches for Olfactory Groove Meningiomas: A Cost-Minimization Study  Voir?

To perform a cost-minimization study comparing the supraorbital and endoscopic endonasal (EEA) approach with or without craniotomy for the resection of olfactory groove meningiomas (OGMs).
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Awake Surgery for Brain Vascular Malformations and Moyamoya Disease  Voir?

Although a significant amount of experience has accumulated for awake procedures for brain tumor, epilepsy, and carotid surgery, its utility for intracranial neurovascular indications remains largely undefined. Awake surgery for select neurovascular cases offers the advantage of precise brain mapping and robust neurologic monitoring during surgery for lesions in eloquent areas, avoidance of potential hemodynamic instability, and possible faster recovery. It also opens the window for perilesional epileptogenic tissue resection with potentially less risk for iatrogenic injury.

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Micro-Multileaf Collimator LINAC Radiosurgery for Vestibular Schwannomas  Voir?

This study evaluates the efficacy of linear accelerator (LINAC) radiosurgery using micro multi-leaf collimator technique (μMLC) in the treatment of a consecutive series of patients with vestibular schwannomas.
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Pilocytic Astrocytoma of fornix mimicking a colloid cyst: report of two cases and review of the literature  Voir?

Colloid cyst is a gelatin-containing cyst in the brain almost always found in the third ventricle. The specific shape and location of these cysts, a round well-delineated mass in the rostral part of the third ventricle adjacent to the foramen of Monro, on imaging are the main findings for diagnosis. Several masses of the third ventricle masquerading colloid cysts on images have been reported yet. Based on different surgical approach, pre-operative misdiagnosis of colloid cyst may have great impact on prognosis.

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Chronic Spinal Subdural Hematoma Associated with Antiplatelet Therapy  Voir?

Spinal subdural hematoma is a rare clinical entity marked by the onset of pain and paralysis, which is usually associated with hemorrhagic disorders, trauma, and iatrogenic causes such as lumbar puncture or epidural anesthesia.
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WITHDRAWN: The modified impact factor; a letter to the editor  Voir?

This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause.The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy.
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WITHDRAWN: Outcomes After Anterior Lumbar Interbody Fusion Versus Transforaminal Lumbar Interbody Fusion for the Treatment of Symptomatic L5–S1 Spondylolisthesis: A Prospective, Multi-Institutional Comparative Effectiveness Study  Voir?

Available online 25 September 2015
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WITHDRAWN: Refining the Role for Evacuation of Spontaneous Intracerebral Hematomas: Results of STICH II  Voir?

The Publisher regrets that this article is an accidental duplication of an article that has already been published, DOI of original article: http://dx.doi.org/10.1016/j.wneu.2014.08.046. The duplicate article has therefore been withdrawn.The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy.

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Upcoming Events  Voir?

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Editor's Choices  Voir?

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Subscription Information  Voir?

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Editorial Board  Voir?

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Contents  Voir?

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Calling  Voir?

In my relatively extensive international travels, I remain in perpetual awe regarding the quality of neurosurgery practiced worldwide. As I meander through the abyss of worldwide neurosurgery, I am constantly reminded of the impressive prowess by which neurosurgeons practice their craft, regardless of the available resources, existing conditions, and most impressively, with the relative disregard to individual economic and “academic” rewards. What is it that makes neurosurgeons tick? What are the factors that stimulate us to, in many cases, overcome substantial barriers and obstacles without significant regard for self (selflessness)?

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In Reply to the Letter to the Editor Regarding “Prophylactic Antiepileptic Drug Use in Patients with Brain Tumors Undergoing Craniotomy”  Voir?

Thank you for the opportunity to share our original research paper in WORLD NEUROSURGERY entitled “Prophylactic Antiepileptic Drug Use in Patients with Brain Tumors Undergoing Craniotomy.” Our work demonstrated that prophylactic antiepileptic drugs (AEDs) did not reduce the likelihood of a postoperative seizure. We also found that AEDs were often continued despite no recurrence of seizures in the postoperative period.

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In Reply to “Postoperative Depression Following Spinal Fusion Surgery; Is There a Role for Elevated Serum Levels of Cobalt and Chromium?”  Voir?

We thank you for the opportunity to respond to Dr. Derakhshan's letter regarding our article.1 Dr. Derakhshan's attempt to suggest a link between the incidence of postoperative depression with elevated serum levels of cobalt and chromium in patients undergoing spinal fusion surgeries is well received. The current literature discussing the existence of such a link is lacking, except for a few case reports including a case series2 cited in Dr. Derakhshan's letter.

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In Reply to the Letter to the Editor Regarding “Effects of Oral Glibenclamide on Brain Contusion Volume and Functional Outcome of Patients with Moderate and Severe Traumatic Brain Injuries: A Randomized Double-Blind Placebo-Controlled Clinical Trial”  Voir?

We have read with interest the comments raised by Garg and Singh regarding our previously published article in WORLD NEUROSURGERY.1 Our published study tries to determine the effects of the oral glibenclamide on the contusion volume and functional outcome of patients with moderate and severe traumatic brain injury (TBI). The study design was a randomized, double-blind, placebo-controlled trial, and the primary endpoint was the contusion volume on admission and on the third and seventh day of admission.

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In Reply to the Letter to the Editor Regarding “Safety and Efficacy of Noncompliant Balloon Angioplasty for the Treatment of Subarachnoid Hemorrhage-Induced Vasospasm: A Multicenter Study”  Voir?

We appreciate the comments on our article, “Safety and efficacy of noncompliant balloon angioplasty for the treatment of subarachnoid hemorrhage-induced vasospasm: a multicenter study.”1 These comments highlight important questions related to the study: How does angioplasty using noncompliant balloons compare with alternative treatment modalities for, or the natural history of, large vessel cerebral vasospasm? Are noncompliant balloons preferable to compliant balloons? What is the role of balloon angioplasty in patients who cannot tolerate aggressive hyperdynamic therapy? Should we consider balloon angioplasty a first-line treatment?

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Postoperative Depression Following Spinal Fusion Surgery; Is There a Role for Elevated Serum Levels of Cobalt and Chromium?  Voir?

I read the recent article by Gaudin et al.1 with great interest. The authors state that despite recent advancements regarding fusion techniques, newly introduced instruments and increased use of minimally invasive procedures, clinical outcomes might not be satisfactory in a large percentage of patients.

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In Reply to “A Neurosurgical Stratagem: Doing the Same with Less?”  Voir?

We very much appreciate the interest that Dr. Alberio et al showed in our recent paper.1 We agree with their opinions about the rationales of early and immediate evacuation of the intracerebral hemorrhage (ICH) through a minimally invasive approach. We also appreciate that they shared their experiences of using a new low-cost technique to perform ICH evacuation.

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In Reply to “Indication of Surgical Management of Vestibular Schwannoma in the Older Age Group: Mysteries Still Unsolved”  Voir?

We appreciate the thoughtful and thorough letter from Satyarthee and Jain1 regarding our article, “Surgical Treatment of Vestibular Schwannoma: Does Age Matter?”2 With the increasing number of older patients, optimal management of vestibular schwannomas in this population is a critical topic.
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In Reply to “Does Spinal Cord Line Influence Choice of Surgical Approach in Multilevel Cervical Spondylotic Myelopathy?”  Voir?

Thank you very much to the reviewer for his letter and advice in regard to our article, “The Spinal Cord Line Can Predict Postoperative Recovery Effect for Multilevel Cervical Spondylotic Myelopathy.”1 It is a great honor to have an exchange of communications with him.
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Letter to the Editor Regarding “Safety and Efficacy of Noncompliant Balloon Angioplasty for the Treatment of Subarachnoid Hemorrhage–Induced Vasospasm: A Multicenter Study”  Voir?

Recently we read with great interest the article by Patel et al,1 published in WORLD NEUROSURGERY, February 2017. They summarized 12-year data about noncompliant balloon angioplasty for vasospasm following subarachnoid hemorrhage, indicating it as an effective and safe measure. However, we are concerned that some issues limit the validity of the study.

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In Reply to “Predicting Shape, Location, and Course of Facial Nerve in Relation to Large Vestibular Schwannoma on Diffusion Tensor Imaging with Intraoperative Correlation: Important Surgical Adjunct”  Voir?

We really appreciate the favorable comments raised in the letter from Dr. Guru Dutta Satyarthee regarding our recently published study1 on the association between diffusion tensor imaging (DTI) analysis and the features of the facial nerve in large vestibular schwannomas. The viewpoints of Dr. Satyarthee, along with the findings in our study, suggest that the application of DTI-based fiber tracking may provide important adjunct information for the surgeon preoperatively, which would allow one to plan the tumor removal accordingly and improve the feasibility of anatomic and functional preservation of the facial nerve.

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In Reply to “Small Stories: In Defense of the Humble Case Report”  Voir?

We are very grateful to Graffeo et al for their comments on our editorial.1 The authors eloquently delineated the importance of case reports in the advancement of our field in accordance with our previous editorial, providing an illustrative example from their own experience on the association between craniopharyngioma and Gardner syndrome. Moreover, they shed further light on the role of case reports in aiding young neurosurgeons and junior faculty to establish an academic record and contribute to academia.

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Letter to the Editor Regarding “Effects of Oral Glibenclamide on Brain Contusion Volume and Functional Outcome of Patients with Moderate and Severe Traumatic Brain Injuries: A Randomized Double-Blind Placebo-Controlled Clinical Trial”  Voir?

We read the article titled “Effects of Oral Glibenclamide on Brain Contusion Volume and Functional Outcome of Patients with Moderate and Severe Traumatic Brain Injuries: A Randomized Double-Blind Placebo-Controlled Clinical Trial” by Khalili et al1 with great interest. We commend the authors for their work. Traumatic brain injury is an epidemic, and we need to find new therapeutic agents to reduce brain edema, hence decreasing the intracranial pressure. However, we have a few concerns about the study published and would like to bring them to the attention of the readers.

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Letter to the Editor Regarding “Prophylactic Antiepileptic Drug Use in Patients with Brain Tumors Undergoing Craniotomy”  Voir?

We read with interest the article entitled “Prophylactic Antiepileptic Drug Use in Patients with Brain Tumors Undergoing Craniotomy,” published recently in WORLD NEUROSURGERY.1 We found this article well written and full of interesting analyses. In this study, the authors performed a retrospective review of 606 patients treated surgically for brain tumors and tried to determine whether the prophylactic use of antiepileptic drugs (AEDs) is justified in seizure-free patients undergoing craniotomy.

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A Neurosurgical Stratagem: Doing the Same with Less?  Voir?

We have read and much appreciated the article by Ma et al.,1 entitled “Endoscopic Evacuation of Basal Ganglia Hematoma: Surgical Technique, Outcome and Learning Curve,” recently published in WORLD NEUROSURGERY, in which the authors describe their experience with evacuation of basal ganglia hematomas through minimally invasive surgery by an endoscopic technique. Intracerebral hemorrhage (ICH) is the most common type of stroke, accounting for up to 15% of all stroke cases. ICH incidence has increased with advanced age, and its prognosis remains poor.

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Small Stories: In Defense of the Humble Case Report  Voir?

We have followed closely the correspondence surrounding your recent editorial “The Diminishing Value of “The Case Report?” including the letter authored by Abou-Al-Shaar and Sabbagh, and your reply.1-3 We agree wholeheartedly with our colleagues and their arguments in support of the case report—chiefly, that cases constitute an important forum for documenting early, rare, or unexpected discoveries. Similarly, they are an essential venue for describing technical innovations, unexpected complications, unusual associations, emergent entities, incompletely understood cases, or other singular entities that may be of interest to the general audience.

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Does Spinal Cord Line Influence Choice of Surgical Approach in Multilevel Cervical Spondylotic Myelopathy?  Voir?

This is in reference to the article by Tong M-J, Hu Y-B, Wang X-Y, Zhu S-P, Tian N-F, Fang M-Q, et al1 in a recent issue of WORLD NEUROSURGERY. The authors attempted to define a new classification to predict postoperative recovery effect for multilevel cervical spondylotic myelopathy patients using a new spinal cord line based on T2-weighted magnetic resonance imaging (MRI).

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In Reply to “Intraocular Silicone Oil Migration into the Ventricles Resembling Intraventricular Hemorrhage: Case Report and Review of the Literature”  Voir?

We have read with interest the article by Filippidis et al.1 We absolutely agree with the authors when they say that clinicians should be aware of this rare disorder and that meticulous history-taking and assessment of patient presentation help to ensure a correct diagnosis. Nevertheless, they provide no information about the aspect of the optic disc, the intraocular pressure (IOP) of the patient, or the type and viscosity of the silicone oil (SiO) used. These clinical data regarding the presence of any of these predisposing factors in this patient are important because they might have played a crucial role in physical SiO migration.

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Single Stage Surgery Avoiding Cranioplasty at a Later Date Following Decompressive Hemicraniectomy  Voir?

It was with great interest that I read the article by Stoner et al.1 published in the December 2016 issue of WORLD NEUROSURGERY. Devising a surgical procedure that in a single operative session achieves the intended decompression of hemicraniectomy while avoiding a second surgery in the form of cranioplasty is a great idea. To that end, the authors' efforts are commendable, and I congratulate them on their work.

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Predicting Shape, Location, and Course of Facial Nerve in Relation to Large Vestibular Schwannoma on Diffusion Tensor Imaging with Intraoperative Correlation: Important Surgical Adjunct  Voir?

The article by Zhang et al.,1 entitled “Preoperative Prediction of Location and Shape of Facial Nerve in Patients with Large Vestibular Schwannomas Using Diffusion Tensor Imaging–Based Fiber Tracking,” published recently in WORLD NEUROSURGERY, was read with great interest. The facial and vestibulocochlear nerve complex occupies a different position and course in relation to the larger vestibular schwannoma and shows morphologic alteration by compression effects, displacement, and varied degrees of adherence to the capsule of schwannomas.

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Rosette-Forming Glioneuronal Tumor Arising from the Spinal Cord  Voir?

In a paper recently published in WORLD NEUROSURGERY, Duan et al.1 reviewed the literature for cases of rosette-forming glioneuronal tumor originating from the spinal cord. They concluded that prior to their report, 3 such cases have been reported.2-4 They also concluded that rosette-forming glioneuronal tumor was the sole lesion in 2 of these reports.2,4 However, the case reported by Rickert et al.4 is not a case of rosette-forming glioneuronal tumor, but that of rosetted glioneuronal tumor, also known as glioneuronal tumor with neuropil-like islands.

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Dernière mise à jour : 19/09/2017 : 04:03


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