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Sommaires des Revues - Word Neurosurgery

World Neurosurgery

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Early Emerging Markers Of Delayed Cerebral Ischemia Following Aneurysmal Subarachnoid Hemorrhage: A Literature Review  Voir?

Delayed cerebral ischemia following aneurysmal subarachnoid hemorrhage is characterized by a highly complex pathophysiology and results in neurological deterioration after the inciting bleed. Despite its significant consequences, prompt diagnosis can be elusive and treatment is often administered too late. Early brain injury, which occurs within the first 72 hours post-ictus, may be an important factor for delayed cerebral ischemia and poor overall outcome. Here we explore the purported clinical and pathological manifestations of early brain injury to identify biomarkers that could have prognostic value.

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Cochlear nerve action potential monitoring for preserving function of an unseen cochlear nerve in vestibular schwannoma surgery  Voir?

Intraoperative monitoring of cochlear nerve action potential (CNAP) has been used in patients with small vestibular schwannoma (<15 mm) to preserve cochlear nerve function. We performed surgery for a larger vestibular schwannoma under CNAP monitoring and preserved cochlear nerve function, as compared with that in 10 normal patients showing hemifacial spasm.

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External ventricular drainage preceding the removal of a nail from the intracranial space as a safe management strategy for predicted secondary intraventricular hemorrhage  Voir?

Intracranial nail gun injury is a rare traumatic event and can result from a suicide attempt. Cerebral angiography is essential in the evaluation of damage to the intracranial vessels, and surgical removal of nails is generally the optimal treatment. Intraventricular hemorrhage can happen following removal of intracranial nails. Endovascular surgery or intraoperative computed tomography has been reported to be useful for detection and treatment of intraventricular hemorrhage. After the surgical removal of nails, attention should be paid for complications such as pseudoaneurysm and infection.

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Use of sodium fluorescein in meningioma surgery performed under the YELLOW-560 nm surgical microscope filter: Feasibility and preliminary results  Voir?

To evaluate the feasibility of sodium fluorescein (Na-Fl)-guided surgery involving the use of the PENTERO 900 surgical microscope (Carl Zeiss, Meditec, Oberkochen, Germany) equipped with the YELLOW-560 nm filter and low-dose Na-FL (200 mg/2–4 mg/kg) in meningioma surgery.
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Use of Laser in AVM surgery  Voir?

AVM surgery is particularly demanding as for the bleeding control of small deep white matter vessels during and after the removal of the nidus, this representing probably one of the most critical moments of AVMs surgery.
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Postoperative Radiculopathy caused by a Retained Fractured Pedicle Cannulation Probe and its Mechanism of Extraction: a Case Report  Voir?

Spine surgery relies heavily on technology and surgical instrumentation. Improperly used instrumentation can be detrimental to the patient. Despite multiple checkpoints to ensure foreign bodies are not retained in surgery, numerous case reports have described retained foreign bodies1-5, however, none of these cases involve retained instrumentation after open spine surgery. Of the retained objects, four were sponges and one was a Jamshidi needle fragment. While smaller objects are more commonly the culprits, surgical instruments can break off, remain stuck, and cause clinical sequelae.

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Indeterminate Dendritic Cell Tumor in Thoracic Spine: A Case Report and Review of Literature  Voir?

Indeterminate dendritic cell tumor (IDCT) is an extremely rare hematological disorder with poorly understood pathogenesis. Occasionally encountered by hematologists, unusual presentations of IDCT have never been reported in the spine literature. The authors report a case of a 51-year-old man who presented with progressively worsening axial thoracic back pain radiating to his sides for three months. MRI revealed a large 3-cm enhancing mass at the T9 vertebral body with an exophytic component causing significant canal stenosis.

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Subdural Fluid Collection and Hydrocephalus after Foramen Magnum Decompression for Chiari Malformation Type I: Management Algorithm of a rare complication. Case Report  Voir?

Chiari Malformation Type I is a hindbrain abnormality characterized by cerebellar tonsils descent beneath the foramen magnum, frequently associated with symptoms or brainstem compression, impaired cerebrospinal fluid circulation and syringomyelia. Foramen magnum decompression represents the most common way of treatment. Rarely, subdural fluid collection and hydrocephalus represent postoperative adverse events. The treatment of this complication is still debated, and physicians sometimes are faced with the doubt of when undergoing diversion surgery and when more conservative managements.

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Bevacizumab for radiation associated visual decline among aggressive residual/recurrent suprasellar tumors: More than a mere anti-neoplastic effect  Voir?

Angiogenesis and vascular endothelial growth factor (VEGF) are recently being implicated in animal and clinical models of radiation-induced optic nerve-retinal and brain necrosis. Though there are isolated case reports of anti-VEGF therapy (Bevacizumab) as a treatment modality in the management of radiation induced brain necrosis, there is paucity of data defining its role in radiation induced optic nerve damage.

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Microvascular decompression for trigeminal neuralgia using a novel fenestrated clip and tentorial flap technique.  Voir?

Microvascular decompression (MVD) for neurovascular compression syndromes such as trigeminal neuralgia and hemifacial spasm has been traditionally described as an interposing technique using Teflon. Some alternative interposing materials have been proposed. Additionally, transposing techniques have been increasingly reported in recent years, as an alternative that may have a lower recurrence rate and fewer complications.

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Improving the prognostic value of disease specific Graded Prognostic Assessment (ds-GPA) model for renal cell carcinoma by incorporation of Cumulative Intracranial Tumor Volume (CITV)  Voir?

We tested the prognostic value of cumulative intracranial tumor volume (CITV) in the context of ds-GPA model for renal cell carcinoma (RCC) patients with brain metastasis (BM) treated with stereotactic radiosurgery (SRS).
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The Pathogenesis of Chronic Subdural Hematomas A Study on the Formation of Chronic Subdural Hematomas and Analysis of Ct Findings  Voir?

The origin of chronic subdural hematomas (CSDH) and the pathophysiology of its enlargement remain unknown. The chemical fluid composition of CSDH the contribution of CSF to its enlargement and the relationship to its appearance on CT appearance is also not entirely clear.In this prospective study, 58 samples in 41 patients treated surgically for CSDH were analyzed. The CSDH were evaluated for the presence of CSF using beta-2 transferrin (β2T) and substances, related to cell breakdown and hemolysis.

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Symptomatic thoracic nerve root herniation into an extradural arachnoid cyst: Case report and review of the literature  Voir?

Spinal extradural arachnoid cysts (SEAC) are relatively rare and usually asymptomatic. They preferentially are situated in the thoracic extradural space, and almost always dorsal. SEACs may present with back pain and/or cord compression symptoms. Needle aspiration, needle fenestration or open surgical resection/fenestration have been reported as treatment modalities.

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Probabilistic tractography of the cranial nerves in vestibular schwannoma  Voir?

Multiple recent studies have reported on diffusion tensor-based fiber tracking of cranial nerves in vestibular schwannoma, with conflicting results as to the accuracy of the method and the occurrence of cochlear nerve depiction. Probabilistic non-tensor based tractography might offer advantages in terms of better extraction of directional information from the underlying data in cranial nerves, which are of sub-voxel size.

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Accuracy of Novel CT-guided Frameless Stereotactic Drilling and Catheter System in Human Cadavers  Voir?

In the present study, we evaluate the accuracy of a CT-guided frameless stereotactic drilling and catheter system.
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Histology-stratified tumor control and patient survival following stereotactic radiosurgery for pineal region tumors: a report from the International Gamma Knife Research Foundation  Voir?

Pineal region tumors represent a rare and histologically diverse group of lesions. Few studies are available to guide management and the outcomes following stereotactic radiosurgery (SRS) are unknown for many histologies.
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Lumbosacral Transitional Vertebra: Possible Role in the Pathogenesis of Adolescent Lumbar Disc Herniation  Voir?

To investigate the role of lumbosacral transitional vertebra (LSTV) in the pathogenesis of adolescent lumbar disc herniation (ALDH) and the association between LSTV type and the herniation level of ALDH.
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Identification of Driver Genes and Key Pathways of Pediatric Brain Tumor and Comparison of Molecular Pathogenesis Based on Pathological Types  Voir?

This study is to identify pediatric brain tumors (PBT) diver genes, key pathways, to detect the expression of the diver genes and also to clarify the relationship between patients’ prognosis and diver genes expression.
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Prognostic factors of hearing outcome in untreated vestibular schwannomas: implication of subdivision of their growth by volumetric analysis  Voir?

Conservative wait-and-scan management for vestibular schwannomas (VSs) is an important treatment option, but its role is unclear because of discordance between tumor growth and hearing outcomes.
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Impact of Gender Disparities on Short- and Long-Term Patient Reported Outcomes and Satisfaction Measures After Elective Lumbar-Spine Surgery: A Single Institutional Study of 384 Patients  Voir?

There is a paucity of data determining the impact that gender disparities have on spine outcomes, particularly perception of health and satisfaction. The aim of this study was to determine whether there is a difference in three-month and one-year PROs and satisfaction after elective lumbar-spine surgery.

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Traumatic Brain Injury and Mood stabilizers: Recent cumulative evidence  Voir?

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Bionic-Brain: Controlling a prosthetic hand  Voir?

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Endopelvic approach for iliac crest bone harvesting: Technical Note  Voir?

The anterior approach to lumbar spine surgery has grown in popularity in the past few years; spinal fusion of the last two lumbar levels is often required. While there are alternatives to bone grafting available, including recombinant human bone morphogenetic protein 2 or bone substitutes, only cancellous autologous bone has all the required factors for bone growth. To avoid the use of bone substitutes, remote iliac crest bone harvesting remains the gold standard. However, this technique may lead to some unfavorable outcomes.

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Novel Use of the Leksell Gamma Frame for Stereotactic Biopsy of Posterior Fossa Lesions: Technical Note  Voir?

Stereotactic transcerebellar biopsies of brainstem tumors have often been reported. The Leksell frame or Cosman–Roberts–Wells frame is often used in transcerebellar approaches. However, to access lesions via the cerebellum, these frames should be secured as inferiorly on the cranium as possible, which can require exaggerated neck flexion and limit the flexible trajectory to the target. To overcome these disadvantages, we have devised a new way to use the Leksell frame for transcerebellar approaches.

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The trigeminocardiac reflex during the anterior transpetrosal approach  Voir?

The anterior transpetrosal approach (ATPA), during which the trigeminal nerve is manipulated, has a risk of eliciting the trigemino-cardiac reflex (TCR). The objective of this study was to assess the risk of the TCR during the ATPA.
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Clinical Observation of Posterior Percutaneous Full-Endoscopic Cervical Foraminotomy as a Treatment for Osseous Foraminal Stenosis  Voir?

To observe the clinical effects of posterior percutaneous full-endoscopic cervical foraminotomy in patients with osseous foraminal stenosis.
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Effective intraluminal shunt in carotid endarterectomy for carotid artery near occlusion: A technical report  Voir?

Carotid artery near occlusion is a critical degree of stenosis whereby blood flow is decreased and the distal cervical and intracranial internal carotid arteries (ICAs) are prone to collapse. Considering the diminished perfusion and the risk of progression to total occlusion and periocclusive embolism, we performed carotid endarterectomy (CEA) for carotid artery near occlusion.

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Novel Technique of Percutaneous Fat Graft for Repair of Persistent Large Pseudomeningocele  Voir?

Pseudomeningocele is an uncommon but problematic complication in lumbar spine surgery. Initial conservative measures are frequently successful but persistence requires additional management. The current surgical approach can involve a range of techniques, including blood patches, hydrogel/fibrin sealants, drains, open surgical repair of the dura or a combination of the above if symptoms persist. This report demonstrates a novel technique for repair using a percutaneous approach to deliver an autologous fat graft into the pseudomeningocele.

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C2 Bone Erosion Secondary to Iatrogenic Pseudomeningocele: A Case Report and Description of a Novel Surgical Technique  Voir?

Pseudomeningoceles are a rare cause of bone erosions. Development of such erosions in the C2 vertebral body and the odontoid process can lead to life-threatening instability. Treatment options to regain stability include atlantoaxial and occipitocervical fusion. For patients with a history of Chiari decompression and large C2 lesions, common fusion techniques are not always feasible. Additionally fusion surgery sacrifices physiologic motion and is therefore a disabling procedure, especially for young and active patients.

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Completion of the Circle of Willis Varies by Gender, Age, and Indication for CTA  Voir?

The Circle of Willis (CoW) is the foremost anastomosis and blood distribution center of the brain. Its effectiveness depends on its completion and the size and patency of its vessels. Gender- and age-related anatomical variations in the CoW may play an important role in the pathogenesis of cerebrovascular diseases. In this study, we analyzed CT angiograms to assess for differences in CoW completion related to gender, age, and indication for CTA.

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The effect of biocomposite screws on bone regeneration in a rat osteoporosis model  Voir?

The aim of this study was to evaluate the efficacy of biocomposite screws used in ovariectomy (OVX) induced osteoporotic rats.
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Preoperative frailty score predicts 30-day morbidity and mortality following cranial neurosurgery  Voir?

Evaluating preoperative frailty is critical for guiding shared surgical decision-making. The purpose of this study was to develop a novel preoperative frailty index for prediction of adverse outcomes following cranial neurosurgery procedures.
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Finite Element Analysis of Influence of Axial Position of Center of Rotation of a Cervical Total Disc Replacement on Biomechanical Parameters: Simulated Two-Level Replacement Based on a Validated Model  Voir?

Finite element (FE) models have been widely used to predict biomechanical parameters of the cervical spine. Previous studies investigated the influence of position of rotational centers (RCs) of prostheses on the cervical biomechanical parameters after one-level total disc replacement (TDR). The purpose of this study was to make a further step by exploring the effects of axial position of RCs of prostheses on the cervical biomechanics after 2-level TDR. A validated FE model of C3-C7 segments and 2 prostheses, including the RC located at the superior endplate (SE) and inferior endplate (IE), was developed.

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Antibiotic prophylaxis in endoscopic endonasal pituitary and skull base surgery  Voir?

Postoperative infection is a potentially dramatic consequence in endoscopic endonasal surgery. The aim of this study is to assess the efficacy of our intraoperative antibiotic prophylaxis, analyzing the risk factors of postoperative meningitis in our series.
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Shifting Treatment Paradigms for Ruptured Aneurysms from Open Surgery to Endovascular Therapy Over 25 Years  Voir?

Since the introduction of GDCs in the early 1990s, major clinical studies have supported an increasing role for coil embolization of ruptured aneurysms. We assessed aneurysm location and treatment modality in aneurysmal subarachnoid hemorrhage (aSAH) over the past 25 years.
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Efficacy of closed continuous lumbar drainage on the treatment of post-craniotomy meningitis: a retrospective analysis of 1062 cases  Voir?

Post-craniotomy meningitis is a severe complication in neurosurgery, and can result in high morbidity and mortality. Closed continuous lumbar drainage (CCLD) as an adjuvant method for treating post-craniotomy meningitis in adults is rarely assessed. This study aimed to evaluate the efficacy of CCLD in the treatment of post-craniotomy meningitis.

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Sport-related structural brain injury: Three cases of subdural hemorrhage in American high school football  Voir?

The risk of sport-related concussion (SRC) has emerged as a major public health concern. In rare instances, sport-related head injuries can be even more severe, such as subdural hemorrhage, epidural hemorrhage, or malignant cerebral edema. Unlike SRCs, sport-related structural brain injury (SRSBI) is rare, may require neurosurgical intervention, and can lead to permanent neurologic deficit or death. Data characterizing SRSBI is limited and many have recognized the need to better understand these catastrophic brain injuries.

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Incidence, Demographics and Outcome of Traumatic Brain Injury in The Middle East: A Systematic Review  Voir?

Traumatic brain injury (TBI) is a serious global public health challenge. We aimed to assess the pattern of TBI in the Middle East, as reported in the last decade.
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Intraoperative Ultrasound in Patients Undergoing Transsphoidal Surgery for Pituitary Adenoma: A Systematic Review  Voir?

Transsphenoidal surgery is the gold standard for pituitary adenoma resection. However, despite advances in microsurgical and endoscopic techniques, some pituitary adenomas can be challenging to cure.
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Pathological Progression, Possible Origin and Management of Multiple Primary Intracranial Neuroendocrine Carcinomas: A Case Report  Voir?

Primary intracranial neuroendocrine carcinomas (NECs) are extremely rare malignant tumors with no previous reports of multiple ones in the literatures.
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Endoscope assisted Abscess drainage secondary to endoscope-assisted TLIF – 1 year follow up  Voir?

Endoscopic discectomy and fusions have been gaining popularity in the recent past and are noted to be safe for its application in elderly population. It involves ultra-small incision for discectomy followed by placement of percutaneous screws in awake patients. Treatment of advanced spinal pathology using endoscope-assisted techniques are challenging. Although not common with endoscopic approach, post-operative infection can be problematic as there are no established guidelines on its management.

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Ventral lumbar synovial cyst causing cauda equina compression: case report and literature review  Voir?

Juxtafacet spinal cysts are cystic synovial lesions that are often indistinguishable clinically or radiologically and require histopathology analysis to confirm the diagnosis. Lumbar synovial cysts usually arising from the synovium of the facet joints. They have been described posterolateral or rarely in the posterior midline. However, we describe the first synovial cyst ventral to the dural sac.

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Intraventricular Meningioma Resection with Post-Operative Ischemia of the Lateral Geniculate Nucleus  Voir?

Intraventricular meningiomas (IVMs) comprise 0.5-3% of intracranial meningiomas. They often cause obstructive hydrocephalus and are commonly treated with surgical resection or stereotactic radiosurgery.
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Neurological outcome after resection of parietal lobe including primary somatosensory cortex: implications of additional resection of posterior parietal cortex  Voir?

Postoperative neurological outcomes after primary somatosensory cortex (S1) resection have not been well-documented. This study was designed to evaluate the neurological deterioration that follows resection of the S1 areas and to assess the risk factors associated with these morbidities.
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Outpatient lumbar microdiscectomy in France: From an economic imperative to a clinical standard - An observational study of 201 cases  Voir?

The outpatient lumbar discectomy procedures have been established for more than two decades. However, especially in Europe, there are still obstacles to the development of these procedures, which may be related to medico-economic imperatives, and to several factors concerning both surgeons and patients. We describe our initial experience in introducing this method in our institution.

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A CT-based Comparison of Abnormal Vertebrae Pedicles between Dystrophic and Nondystrophic Scoliosis in Neurofibromatosis Type 1  Voir?

To explore the prevalence and distribution of abnormal vertebral pedicles in scoliosis secondary to neurofibromatosis type 1 (NF1-S) and to compare the abnormal vertebrae pedicles between dystrophic and nondystrophic scoliosis.
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Bifurcation location and growth of aneurysm size are significantly associated with an irregular shape of unruptured intracranial aneurysms  Voir?

Previous studies firmly proved that an irregular aneurysmal shape was strongly associated with intracranial aneurysm (IA) rupture, but it is unclear how irregularly shaped intracranial aneurysms (IAs) form. We aimed to identify the factors related to irregular shape of IAs.
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Survival patterns of 5750 SRS-treated brain metastasis patients as a function of the number of lesions  Voir?

The number of brain metastases (BM) plays an important role in the decision between stereotactic radiosurgery (SRS) and whole brain radiation therapy (WBRT).
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The Fate of Adult Spinal Deformity (ASD) Patients Incurring Rod Fracture After Thoracolumbar Fusion  Voir?

To report the outcome of adult spinal deformity (ASD) patients with rod fracture following thoracolumbar fusion.
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A Hemispheric Chronic Subdural Hematoma concealing Subdural Metastases. A Terrible Surprise behind a routine Emergency Room consultation  Voir?

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Mini-craniotomy under local anesthesia for chronic subdural hematoma: An effective choice for elderly and for patients in a resource strained environment  Voir?

Mini craniotomy for chronic subdural hematoma (CSDH) is associated with lower recurrence rates. However, the procedure is mostly performed under general anesthesia (GA) and therefore frequently requires intensive care unit (ICU) facility, especially in the elderly population. Due to unavailability of ICU beds, and to avoid GA, we started to perform this procedure under local anesthesia (LA).

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Multilevel spinal segmental fixation for kyphotic cervical spinal deformity in pediatric age group-report of management in 2 cases  Voir?

We discuss the role of instability of multiple segments of spine that includes atlantoaxial joint in pathogenesis of cervical kyphotic deformity.
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Isolated subcallosal artery infarction secondary to localised cerebral vasospasm of anterior communicating artery complex following subarachnoid haemorrhage  Voir?

Subcallosal artery (ScA) infarction is a well-recognised, but uncommon complication of surgical treatment of anterior communicating artery (ACOM) aneurysms.
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Endonasal operative corridor expansion by sphenoidal pneumosinus dilatans in tuberculum sellae meningiomas  Voir?

A retrospective cohort study of patients with tuberculum sellae meningioma (TSM)-associated sphenoidal pneumosinus dilatans (PSD) over a recent epoch was evaluated using a propensity-matched morphometric analysis.A total of 38 patients with TSM and sphenoidal PSD were identified and matched by age and sex to 32 patients without tumors (controls). Overall, no significant difference between test and control groups was noted in sphenoid sinus size or other parameters; however, significantly greater mean distance from the posterior margin of the planum sphenoidale to the diaphragma sella (0.76 ± 0.23 vs.

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Spinal Instability Predictive Scoring System for Subsequent Fractures after Bone cement augmentation in Patients with Osteoporotic Vertebral Compression Fractures  Voir?

Bone cement augmentation procedures (vertebroplasty and kyphoplasty) are the primary treatments for osteoporotic vertebral compression fractures (VCFs). However, these procedures are associated with various problems resulting in subsequent fractures. The purpose of this study was to evaluate the spinal instability factors related to subsequent fractures after vertebral augmentation procedures.

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Cumulative Intracranial Tumor Volume and Number of Brain Metastasis as Predictors of Developing New Lesions after Stereotactic Radiosurgery for Brain Metastasis  Voir?

The aim of our study was to identify risk factors associated with early distant radiographic progression in patients undergoing stereotactic radiosurgery (SRS) for brain metastases (BM).
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Asleep robot-assisted surgery for the implantation of subthalamic electrodes provides the same clinical improvement and therapeutic window as awake surgery  Voir?

To study the impact of not performing an awake clinical evaluation during the robot-assisted implantation subthalamic nucleus deep brain stimulation (STN-DBS) electrodes on the stimulation parameters and clinical outcome in patients with Parkinson’s disease (PD).
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Seizure Outcome of Patients with Magnetic Resonance Imaging-Negative Epilepsies: Still An Ongoing Debate  Voir?

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Bony Lateral Recess Stenosis and Other Radiographic Predictors of Failed Indirect Decompression via Extreme Lateral Interbody Fusion (XLIF): Multi-Institutional Analysis of 101 Consecutive Spinal Levels  Voir?

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Predictors of recurrence and complications after chronic subdural hematoma surgery: a population-based study  Voir?

To investigate predictors of recurrence and moderate to severe complications after burr-hole surgery for chronic subdural hematoma (cSDH).
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Inherent tumor characteristics that limit effective and safe resection of giant nonfunctioning pituitary adenomas  Voir?

Surgical treatment of giant pituitary adenomas is sometimes challenging. We present our surgical series of giant nonfunctioning adenomas to shed light on the limitations of effective and safe tumor resection.
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Management of arteriovenous malformations associated with developmental venous anomalies: A literature review and report of two cases  Voir?

Cerebrovascular malformation classification has revealed intermediary lesions that warrant further review due to their unusual presentation and management. We present two cases of arteriovenous malformations (AVMs) associated with a developmental venous anomaly (DVA), and discuss the efficacy of previously published management strategies.

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Surgery for Cerebellar Hemorrhage – a NSQIP-Database Analysis of Patient Outcomes and Factors Associated with 30-Day Mortality and Prolonged Ventilation  Voir?

Primary cerebellar hemorrhage accounts for 10% of all intracranial hemorrhages. Given the confined space of the posterior fossa, cerebellar hemorrhage management sometimes necessitates suboccipital decompression and hematoma evacuation. In this study, we examine outcomes following surgery for primary cerebellar hemorrhage, and identify risk factors associated with adverse outcomes.

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Microneurosurgical clip ligation of acutely ruptured cerebral aneurysm immediately preceded by intentional subtotal endovascular coil embolization under a single anesthesia: observations using a deliberate combined sequential treatment strategy in 13 cases  Voir?

Endovascular coil embolization and craniotomy with clip ligation are the two most commonly used treatments for ruptured cerebral aneurysm. While coiling maintains the advantages of brevity and complete avoidance of brain retraction and manipulation, clipping offers the benefits of decompression of the injured brain and lower aneurysm recurrence rates. A combined, immediately sequential treatment strategy for acutely ruptured cerebral aneurysm that simultaneously maximizes the advantages of both techniques, while minimizing their respective disadvantages, may be a useful paradigm.

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The prognostic impact of ventricular opening in glioblastoma surgery: a retrospective single center analysis  Voir?

Ventricular opening during glioblastoma (GBM) resection is controversial. Sufficient evidence regarding its prognostic role is missing. We investigated the impact of ventricular opening on overall survival (OS), hydrocephalus development and postoperative morbidity in GBM patients.
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Nocardia farcinica brain abscess: report of 3 cases  Voir?

Central nervous system nocardial infection is a rarely reported disease that usually affects patients with predisposing and debilitating conditions but also the immunocompetent population. The most common variant affecting the brain is Nocardia farcinica. Management of brain nocardiosis is troublesome and requires consideration of the severity of the underlying systemic disease, the difficulties in identifying the bacterium and the frequent delay in initiating adequate therapy.

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Postoperative dilatation of superficial temporal artery associated with transient neurological symptoms after direct bypass surgery for moyamoya angiopathy  Voir?

In moyamoya angiopathy (MMA), transient neurological symptoms (TNS) are occasionally observed after superficial temporal artery (STA)-middle cerebral artery (MCA) direct bypass surgery. The purpose of this study was to investigate the correlation between TNS and postoperative MR images, as well as perform a perfusion study.

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Population rCharacteristics and Progressive Disability in Neuofibromatosis Type 2  Voir?

To characterize the clinical features of the NF2 population and determine prognostic risk factors for progressive disabilities.
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Usefulness of percutaneous endoscopic lumbar foraminoplasty for lumbar disc herniation  Voir?

Endoscopic foraminoplasty facilitates the engagement of the working cannula via the intervertebral foramen, allowing cannula access near the herniated disc (HD) for the successful application of percutaneous endoscopic lumbar discectomy (PELD). The purpose of this study was to evaluate the efficacy of foraminoplasty for HD and propose applicable situations for foraminoplasty in PELD.

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Application of 3D-computerized tomography angiography for Defining Cavernous Sinus Aneurysms and Intradural Aneurysms Involving the Internal Carotid Artery around the Anterior Clinoid Process  Voir?

The current study aimed to investigate the application of three-dimensional computed tomography angiography (3D-CTA) for defining cavernous sinus aneurysms and intradural aneurysms involving the internal carotid artery around the anterior clinoid process.
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Comparison of grading scales regarding perioperative complications and clinical outcomes of brain arteriovenous malformations after endovascular therapy-a multicenter study  Voir?

Several scales have been proposed for risk assessment and outcome determination in brain arteriovenous malformations (bAVMs) treated by endovascular therapy. We aim to validate and compare the efficacy of these scales in predicting perioperative complications and clinical outcomes.
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Intramedullary Spinal Cord Metastasis from Ovarian Cancer in a 50-Year-Old Female  Voir?

Intramedullary spinal cord metastasis (ISCM) from ovarian cancer is rare. Here, we reported a case of a 50-year-old female with ISCM from ovarian cancer.
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Henry II of France (1519-1559) and his death from meningoencephalitis following a cranial trauma  Voir?

The purpose of this historical review is to summarize the most significant theories on the cause of death of King Henry II of France (1519-1559) and the circumstances under which it occurred. Although the testimonies are inconclusive and vague, post mortem analysis showed that the cause of death of the King was meningoencephalitis, caused by haematoma of cerebral contusion, with effusion in the cerebral laminae, in its surrounding tissue initiated from a periorbital fracture.

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Surgical treatment of segmental spinal dysgenesis: selection of an optimal type of fusion  Voir?

The aim of this study is to select optimal fusion type for segmental spinal dysgenesis (SSD).
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Parent and child balloon technique for navigating guide catheters during neurointerventions  Voir?

and Purpose: The stabilization of a guide catheter is an important factor for performing successful neurointerventional procedures. We present our technique for navigating guide catheters using parent and child balloons.
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Key aspects in foramen magnum meningiomas: From old neuroanatomical conceptions to current far lateral neurosurgical intervention  Voir?

Foramen magnum meningiomas (FMM) represent a challenge for neurosurgeons. These tumors require careful surgical manipulation as they are often located in proximity to critical neurovascular structures and the cranial nerves. The far lateral approach is considered the safest neurosurgical approach for excising foramen magnum lesions. It facilitates the access to the anterior foramen magnum and reduces the retraction of vital structures. We describe key historical, epidemiological, genetic, epigenetic, clinical, and neurosurgical aspects of FMM.

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Iatrogenic ascending pharyngeal artery injury by pre-dilation balloon inflation during carotid artery stenting with flow reversal  Voir?

The ascending pharyngeal artery (APA) may rarely arise from the common carotid artery bifurcation. We herein report an injury to the APA as an unusual complication of pre-dilation balloon inflation during carotid artery stenting (CAS) with flow reversal.
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Iatrogenic vertebral artery injury during anterior cervical spine surgery: A systematic review  Voir?

Iatrogenic vertebral artery injury (VAI) during anterior cervical surgery is rare but potentially catastrophic.
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Endoscopic endonasal transsphenoidal approach for the removal of optochiasmatic cavernoma: a case report and literature review  Voir?

Cavernoma of the optic chiasm is a rare disease, and the most common clinical presentation is chiasmal apoplexy. Almost all the cases reported in the literature were treated surgically with craniotomy.
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Skeletal muscle as a factor contributing to better stratification of older patients with traumatic brain injury: a retrospective cohort study  Voir?

Traumatic brain injury (TBI) in older patients is becoming an increasing problem, and methods that help predict outcomes in this population are needed. The objective of this study was to evaluate skeletal muscle mass as a predictive marker for TBI outcome in older patients.
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Multimodality Treatment of Posterior Inferior Cerebellar Artery Aneurysms  Voir?

Posterior inferior cerebellar artery (PICA) aneurysms are heterogeneous, uncommon lesions that can be treated in many fashions. Many previous series have focused on a specific aneurysm subset or treatment paradigm. The aim of this study was to present a comprehensive approach for all PICA aneurysms and analyze outcomes by PICA location.

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Pitfalls in diagnosis and management of testicular choriocarcinoma metastatic to the brain: Report of two cases and review of literature.  Voir?

Pure choriocarcinoma of the testes is a rare, aggressive germ cell tumor (GCT) that can metastasize to the brain. Although its prognosis has improved with the development of cisplatin-based chemotherapy regimens, cerebral metastases are prone to hemorrhage and are associated with high morbidity. Here, we present two cases of testicular choriocarcinoma with cerebral metastasis and discuss potential pitfalls in their diagnosis and management. We also review cases in the literature that feature these rare lesions.

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Prospective evaluation of the non-invasive Headsense ICP monitor in TBI patients undergoing invasive ICP monitoring  Voir?

Currently intracranial pressure (ICP) is measured by invasive methods with a significant risk of infectious and hemorrhagic complications. Because of these high risks, there is need for a noninvasive ICP (nICP) monitor with an accuracy similar to that of an invasive ICP monitor.
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Design-based Comparison of Spine Surgery Simulators: Optimizing Educational Features of Surgical Simulators  Voir?

Simulation-based education has made its entry into surgical residency training, particularly as an adjunct to hands-on clinical experience. However, one of the ongoing challenges to wide adoption is the capacity of simulators to incorporate educational features required for effective learning. The aim of this study was to identify strengths and limitations of spine simulators to characterize design elements that are essential in enhancing resident education.

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Safety and Efficacy of a 600mg Loading dose of Clopidogrel 24 hours before Pipeline Embolization Device treatment  Voir?

Clopidogrel/aspirin antiplatelet therapy is routinely administered 7 to 10 days prior to pipeline aneurysm treatment. Our study assessed the safety and efficacy of a 600mg loading dose of clopidogrel 24 hours before PED treatment.
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Patient expectations and preferences in the spinal surgery clinic  Voir?

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A Comparison of Pharmacologic Therapeutic Agents used for the Reduction of Intracranial Pressure Following Traumatic Brain Injury  Voir?

In neurotrauma care, a better understanding of treatments following traumatic brain injury (TBI) has led to a significant decrease in morbidity and mortality in this population. TBI represents a significant medical problem, and complications following TBI are associated with the initial injury and post-event intracranial processes such as elevated intracranial pressure (ICP) and brain edema. Consequently, appropriate therapeutic interventions are required to reduce brain tissue damage and improve cerebral perfusion.

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CVS-dependent and CVS-independent Cerebral Infarctions Predict Outcome after Non-Aneurysmal Subarachnoid Hemorrhage: a Single-Center Series with 250 Patients  Voir?

The number of patients with non-aneurysmal subarachnoid hemorrhage (naSAH) has increased over the last decade. Data regarding infarctions in naSAH are still limited. Aim of the study was to identify the rate of cerebral vasospasm (CVS)-dependent and CVS-independent infarctions and their influence on clinical outcomes.

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Initial treatment strategy for intracranial mycotic aneurysms: Two case reports and literature review  Voir?

Intracranial mycotic aneurysm (IMA) is a rare neurovascular disease and a well-known complication following infective endocarditis. IMAs potentially carry a high mortality risk due to intracranial hemorrhage. Therefore, initial treatment is crucial for IMA patients, but an optimal treatment strategy remains unknown. Herein, we report two cases of IMA patients treated with the current usual modalities, and we provide a comprehensive literature review to propose an optimal initial treatment strategy for IMAs.

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An Intraoperative Look At A Residual/Recurrent Tentorial Dural Arteriovenous Fistula  Voir?

Dural arteriovenous fistulas (dAVF)s are often treated via transarterial or transvenous embolization. Incomplete penetration of the draining vein/occult residual will often become apparent on follow-up angiography, requiring repeat embolization, or at times, surgical resection.
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The Outcomes of Primary Transsphenoidal Surgery in Cushing’s Disease: Experience of a Tertiary Center  Voir?

To report the initial and long-term remission rates and related factors, secondary treatments, and outcomes of a series of patients with Cushing’s disease (CD).
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Pitfalls of a neuroendoscopic biopsy of intraventricular germ cell tumors  Voir?

A neuroendoscopic biopsy has become common for the diagnosis of ventricular tumors. However, its utility in patients with germ cell tumors (GCTs) has not been well discussed. We examined the usefulness and pitfalls of neuroendoscopic biopsies of intraventricular GCTs at a single institution.
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Cell Index in the Diagnosis of External Ventricular Drain-Related Infections  Voir?

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Clival defect with primary CSF rhinorrhea: a very rare presentation with challenging management  Voir?

Primary spontaneous cerebrospinal fluid (CSF) rhinorrhea due to clival defect is an extremely rare presentation and only six cases have been reported in the literature so far17. We present a unique case of a 64-year-old lady who presented with 2 years history of ongoing CSF rhinorrhea. She had similar episode at the age of 40 and suffered from meningitis. She had MRI, CT cisternogram as well as CT of brain and that showed clival defect with CSF leak into the sphenoid sinus. She underwent trans-sphenoidal repair of the clival defect with concurrent lumbar drain insertion for CSF drainage.

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Primary intradural extramedullary cervical spinal cysticercosis  Voir?

Spinal cysticercosis has been reported only in 0.7 to 3.0% of patients with neurocysticercosis. Most of the patients with spinal cysticercosis have a coexisting intracranial disease. Most often these present as intradural extramedullary lesions, involving thoracic and lumbar regions or intramedullary lesions. Intradural extramedullary primary spinal cysticercosis presenting as cervical myelopathy is extremely rare and not reported till date.

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In-hospital Complications Following Lumbar Spine Surgery in Patients with Parkinson’s Disease: Evaluation of the National Inpatient Sample Database  Voir?

Previous reports suggest that patients with Parkinson’s disease (PD) have increased complication rates following spine surgery however data from these reports are limited by small patient size. The aim of this study was to utilize the National Inpatient Sample (NIS) database to compare in-hospital complications for PD compared to patients without following elective lumbar spine surgery.

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Symptomatic intracerebral hemorrhage secondary to ventriculoperitoneal shunt in adults without bleeding tendency  Voir?

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Transdural indocyanine green videography for STA-MCA bypass – technical note  Voir?

Neurosurgical application of indocyanine green (ICG) videography prior to performing a dural opening has been reported as transdural ICG videography and used during surgery of meningiomas associated with venous sinuses, as well as cranial and spinal arteriovenous malformations. However, its use for a superficial temporal artery to middle cerebral artery (STA-MCA) bypass has not been reported.

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Transventricular migration of neurocysticercosis  Voir?

A 22-year old male patient presented with the main symptom of diplopia for about a week. Neurological examination revealed bilateral sixth cranial nerve weakness. Investigations during the period showed an intraventricular tumor that migrated from lateral ventricle to the third ventricle and subsequently to the fourth ventricle. The lesion was resected from the fourth ventricle and was identified to be a neurocysticercosis cyst. Such an intraventricular migration of any kind of tumor has not been recorded in the literature.

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Cerebral venous sinus thrombosis secondary to idiopathic hypertrophic cranial pachymeningitis: A case report and review of the literature  Voir?

Idiopathic hypertrophic cranial pachymeningitis (IHCP) is a rare fibrosing inflammatory process involving the dura mater. Currently, there is no consensus on the treatments for IHCP, and the usefulness of immunosuppressive agents as a first-line option remains controversial. Cerebral venous sinus occlusion (CVSO) and cerebral venous sinus thrombosis (CVST) secondary to IHCP, which may cause progressive intracranial hypertension and venous obstructive parenchymal lesions, make the diagnosis and treatment of IHCP more complicated.

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Infection or Glioma? The False Dilemma of Primary CNS Histiocytic Sarcoma  Voir?

Primary CNS histiocytic sarcoma (HS) is an extremely rare lymphoproliferative disorder which affects the central nervous system and behaves aggressively. There have been only twenty-seven reported cases of primary CNS HS. The paucity of literature on this entity has made diagnosis and treatment difficult both for the surgeon and pathologist. This is a case of primary CNS HS in a middle-aged female who presented with a supposed cerebellar abscess from an outside institution. The intraoperative frozen pathology was initially interpreted as a high grade glioma, however the final pathology was demonstrated to be histiocytic sarcoma.

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Increased risk of anxiety or depression after traumatic spinal cord injury in patients with pre-existing hyperlipidemia: a population-based study  Voir?

Anxiety or depression (AD) is a common complication after traumatic spinal cord injury (tSCI). This study sought to investigate the role of pre-existing hyperlipidemia in new-onset AD after tSCI using a longitudinal population database.
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Transforaminal endoscopic lumbar discectomy for lumbar disc herniation causing bilateral symptoms  Voir?

Transforaminal endoscopic lumbar discectomy (TELD), a minimally invasive spinal technique, has advantages over open discectomy. Unilateral TELD for disc herniation causing bilateral symptoms is challenging. In this study, we describe a percutaneous endoscopic herniotomy technique by using a unilateral approach for lumbar disc herniation with bilateral obvious symptoms.

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Trans-anterior communicating artery primary stenting in acute tandem middle cerebral artery-internal carotid artery occlusion due to thoracic aortic stent graft  Voir?

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Image-Guidance to Aid Pedicle Screw Fixation of a Lumbar Fracture-Dislocation Injury in a Toddler  Voir?

Pedicle screw fixation of the lumbar spine in children less than two years of age is particularly challenging, as successful cannulation of the small pedicle dimensions require a high level of precision and there are no implants specifically designed for the infantile spine. Image-guided navigation is commonly used in adult spinal surgery and may be particularly helpful for placement of spinal screws where the bony anatomy is small and/or anatomically complex as in the upper cervical area.

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A case report of preoperative embolization and complete tumoral resection of a cervical aggressive epithelioid osteoblastoma  Voir?

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Management of Pediatric Atlantoaxial Rotatory Subluxation with a Simple Hand-Made Cervical Traction Device; Doing More with Less  Voir?

Atlanto-axial (C1- C2) joint is accountable for up to two third of total axial craniocervical rotation. Its major role in pivotal rotation of cervical spine makes it more vulnerable to a certain type of injury known as atlanto-axial rotatory subluxation (AARS). Management of AARS is based on the Fielding classification which includes closed reduction and immobilization and cervical fusion in unstable cases. There are several cervical traction devices including the Gardner-Wells tongs and halter traction device.

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New Evidence for a Causal Central Mechanism of Hyperglicemia in Subarachnoid Hemorrhage Secondary to Ischemic Degenerative Disruption of circuitry among Insular Cortex, Nodose Ganglion and Pancreas: Experimental Study  Voir?

Although hyperglycemia is serious complication of subarachnoid hemorrhage, its pathophysiologic mechanism based on neural circuitry has not been known.
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Intradural intramedullary teratoma presenting in the lumbar spine: report of a rare case  Voir?

Intradural teratoma is an exceedingly unusual phenomenon. They are tumors with the cellular constituent source of all the three germ cell layers.
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Long-term results of Deep Brain Stimulation of the Anterior Cingulate Cortex for Neuropathic Pain  Voir?

Deep Brain Stimulation of the Anterior Cingulate Cortex is a recent technique that has shown some promising short-term results in patients with chronic refractory neuropathic pain. Three years after the first case-series, we assessed its efficacy on a larger cohort, with longer follow-up.
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Treatment Strategies of subarachnoid hemorrhage from bilateral vertebral artery dissection: A case report and literature review focusing on availability of stent placement  Voir?

Bilateral vertebral artery dissection (VAD) may result in subarachnoid hemorrhage (SAH). However, a variety of factors contribute to the difficulties with treating SAH. We report a case of bilateral VAD with SAH, as well as a literature review.
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Effects of preoperative simulation on minimally invasive Hybrid Lumbar Interbody Fusion (MIS-HLIF)  Voir?

The main focus of this study was to evaluate how preoperative simulation affects the surgical workflow, radiation exposure and outcome of MIS-HLIF.
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A Technique for Resecting Occipital Pole Gliomas Using a Keyhole Lobectomy  Voir?

Our purpose is to describe a method of resecting occipital pole gliomas through a keyhole lobectomy and share the patient outcomes of this technique.
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Piezosurgery in modified pterional orbital decompression surgery in Graves’ disease  Voir?

Piezosurgery utilizes microvibrations to selectively cut bone, preserving the adjacent soft tissue. The present study evaluated the use of piezosurgery for bone removal in orbital decompression surgery in Graves’ disease via a modified pterional approach.
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Incidental primary intradural carcinoid tumor in a patient with lumbar radiculopathy  Voir?

Carcinoid tumors are neuroendocrine neoplasms derived from enterochromaffin cells. Central nervous system involvement is rare. The reported cases include metastases to brain or spinal cord, as well as primary skeletal or extradural disease resulting in compressive myelo-radiculopathy. There are two previously reported cases of primary intradural extramedullary carcinoid tumor, presenting with compressive symptoms. We report the first case of primary incidental intradural extramedullary carcinoid tumor.

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Posterolateral trajectories favor a longer motor domain in STN DBS for Parkinson’s disease  Voir?

The clinical outcome of Parkinson's disease (PD) patients that undergo Subthalamic Nucleus Deep Brain Stimulation (STN DBS) is, in part, determined by the length of the electrode trajectory through the motor STN domain, the Dorso-Lateral Oscillatory Region (DLOR). Trajectory length has been found to correlate with the stimulation-related improvement in patients’ motor function (estimated by part III of the United Parkinson’s Disease Rating Score (UPDRS)). Therefore, it seems that ideally trajectories should have maximal DLOR length.

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Recurrent pituicytoma with pseudoaneurysm: report of a challenging case  Voir?

Pituicytoma is a rare tumor originating from glial cells of the adult neurohypophysis and infundibulum. Surgical removal is the treatment of choice for this neoplasm. In recent years the endoscopic endonasal approach has proven to be a viable and effective alternative to standard craniotomy.
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A Hemorrhagic Clival Chordoma with a Long Progression-Free Survival  Voir?

Chordomas and ecchordosis physaliphora may on rare occasions present with intracranial hemorrhage. Their distinction usually relies on the results of the Ki-67 proliferative index, with a result lower than 1% favoring ecchordosis physaliphora. Intracranial hemorrhagic chordomas have been linked to unfavorable prognosis, due to acute neurologic deterioration and death, or progression after treatment. To the best of our knowledge, this is the first report of a patient with an intracranial hemorrhagic chordoma who had a long progression-free survival.

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Computational fluid dynamics simulation of hemodynamic alterations in sigmoid sinus diverticulum and ipsilateral upstream sinus stenosis after stent implantation in patients with pulsatile tinnitus  Voir?

To investigate the relationships between upstream venous sinus stenosis and pulsatile tinnitus (PT), and to assess the correlation with diverticulum growth and the effectiveness of stent implantation
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Microsurgical repair of ruptured aneurysms associated with moyamoya-pattern collateral vessels of the middle cerebral artery: a report of two cases  Voir?

Patients with Moyamoya or other intracranial steno-occlusive disease are at risk for developing aneurysms associated with flow through collateral vessels. Because these lesions are rare, the optimal management remains unclear. Here, we describe two cases of microsurgical repair of ruptured collateral vessel aneurysms associated with middle cerebral artery (MCA) occlusion.

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Stroke Burden in Rwanda; a multicenter study on stroke management and outcome  Voir?

Cerebro-vascular accidents (CVA) or Stroke constitute the second leading cause of mortality worldwide. Low and middle income countries bear most of stroke burden worldwide. The main objective of this study is to determine the burden of stroke in Rwanda.
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The Superior Frontal Transsulcal Approach to the anterior ventricular system: Exploring the sulcal and subcortical anatomy using anatomic dissections and DTI tractography  Voir?

To explore the superior frontal sulcus morphology, trajectory of the applied surgical corridor and white matter bundles that are traversed during the superior frontal transsulcal transventricular approach
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Intramedullary Cervical Spinal Cord Abscess  Voir?

Intramedullary spinal cord abscesses are rarely encountered in modern neurosurgical practice. Select patients remain at high risk for developing an intramedullary spinal cord abscess, which can result in acute neurologic deficits. Patients with failed conservative management may benefit from early surgical intervention. However, the evidence is limited by level 3 studies. In the following case presentation, the patient failed conservative management for a cervical intramedullary spinal cord abscess and developed acute neurologic deficits.

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Corrigendum to “Clinical Outcomes of Correcting Cervical Deformity in Cerebral Palsy Patients” [World Neurosurgery 96 (2016) 500–509]  Voir?

The authors regret that the Conflict of interest statement in this paper contained an error. The grant number for the Institute for Information & Communications Technology Promotion (IITP) grant funded by the Korea government (MSIP) was given as ‘R0190-16-02072’, however it should have been ‘R0190-16-2072’.

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A Primary Pigmented Choroid Plexus Papilloma Located Within the Sella Turcica: Case Report and Literature Review  Voir?

Choroid plexus papillomas (CPPs) are rare benign tumors, and the pigmented subtype is observed even more rarely.
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Endovascular therapy for the steal phenomenon due to the innominate artery severe stenosis and bilateral internal carotid artery severe stenosis: Case report  Voir?

Symptomatic innominate artery stenosis as hemodynamic bilateral cerebral ischemia is uncommon. We present a rare case of an innominate artery origin severe stenosis and bilateral internal carotid artery (ICA) severe stenosis, inducing hemodynamic cerebral ischemia after ipsilateral axillary artery-bilateral femoral artery bypass, and treated with stent replacement of innominate artery and right ICA.

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Rupture After Bypass and Distal Occlusion of Giant Anterior Circulation Aneurysms  Voir?

Giant aneurysms are very high-risk lesions both in terms of natural history and treatment. Bypass with distal occlusion is thought to be a safe treatment option for these aneurysms. Here, we report 2 cases of aneurysm rupture after bypass and distal occlusion, review the literature, and discuss the possible underlying mechanisms, in the hopes of influencing treatment planning and averting such complications in the future.

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Concomitant Lumbosacral Perimedullary Arteriovenous Fistula and Spinal Dural Arteriovenous Fistula  Voir?

Although multifocal spinal arteriovenous malformations (AVMs) have been reported before, the present case is the first case of 2 different types, including 1 perimedullary arteriovenous fistula and 2 spinal dural arteriovenous fistulas of lumbosacral AVMs, coexisting in 1 patient. We also report the use of hybrid techniques in treatment of concomitant lumbosacral spinal AVMs.

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Pial-Dural Intracranial Arteriovenous Fistula with Flow Associated Aneurysmal Rupture - Case Report with Review of Literature and Proposal on the Mechanism of Hemorrhage and Treatment Options  Voir?

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Risks and benefits of endoscopic transsphenoidal surgery for non-functioning pituitary adenomas in patients of the 9th decade  Voir?

The population over 80 years of age (very elderly) is increasing and the management of these patients with pituitary surgery is controversial. Our study aimed to determine the prevalence of pituitary tumors in the elderly and to determine the safety of endoscopic transsphenoidal pituitary surgery for non-functioning pituitary adenomas in patients aged over 80.

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Cervical Burst Fracture in a Patient with Contiguous 2-Level Cervical Stand-Alone Cages  Voir?

Cervical stand-alone interbody cages have seen increasingly wider use over the plate-and-screw construct in single-level anterior cervical discectomy and fusion (ACDF) in the treatment of cervical disc herniation and degenerative spondylotic conditions. Despite positive clinical outcomes, the efficacy and safety of using these devices in contiguous multilevel ACDF has remained controversial. This report discusses a burst fracture seen as a complication in multilevel cervical stand-alone cage use.

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Endonasal endoscopic odontoidectomy in ventral pathologies of the cranio-cervical junction – Results of a multicenter experience  Voir?

Over the past decades, supported by preliminary anatomical and clinical studies exploring its feasibility and safety, an ever growing experience was built on the use of the endoscopic endonasal approach (EEA) to ventral pathologies at the cranio-cervical junction (CCJ).
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Rates of Seizure Freedom after Surgical Resection of Diffuse Low-Grade Gliomas  Voir?

Patients with diffuse low-grade gliomas (DLGG) typically present with seizures. We sought to review the neurosurgical literature for seizure outcome after resection of these tumors.
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Unruptured paraclinoid aneurysm treatment effects on visual function: a systematic review and meta-analysis  Voir?

Postoperative visual outcomes following repair of unruptured paraclinoid aneurysms (UPAs) are not well defined. We aim to investigate the influence of treatment modality on visual function.
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Endoscopic endonasal surgery for pituitary apoplexy: evidences from a 75-cases series from a tertiary care center  Voir?

The optimal management of PA remains debated. The aim of this study was to assess the outcome of TA in PA in a large surgical experience.
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Outcome after subarachnoid hemorrhage from blood blister-like aneurysm rupture depends on age and aneurysm morphology  Voir?

Blood blister-like aneurysms (BBLA) are rare, prone to rerupture and challenging to treat.
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A Confirmed Case in the United Kingdom of Hirayama Disease in a Young White Male Presenting with Hand Weakness  Voir?

We present the first reported case of Hirayama disease in the United Kingdom. A literature review of Hirayama disease in the Western literature shows that this case is unique in being the first in the United Kingdom, constituting one of only a few cases in Europe with supporting magnetic resonance imaging and reported treatment outcome.

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Predictors of Shunt-dependent Hydrocephalus after Aneurysmal Subarachnoid Hemorrhage? A systematic review and meta-analysis  Voir?

Hydrocephalus is a well-recognized complication following aneurysmal subarachnoid hemorrhage (aSAH). This study aimed to identify predictors for shunt-dependent hydrocephalus (SDHC) following aSAH and via a systematic review and meta-analysis.
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Simultaneous Resection of Multiple Metastatic Brain Tumors with Multiple Keyhole Craniotomies  Voir?

The proper management of symptomatic patients with two or more brain metastases is not entirely clear and the surgical outcomes of these patients undergoing multiple simultaneous craniotomies have not been well described. In this manuscript, we describe patient outcomes after simultaneously resecting metastatic lesions through multiple keyhole craniotomies.

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Intraventricular Cavernomas of the Third Ventricle: Report of 2 Cases and a Systematic Review of the Literature  Voir?

Intraventricular cavernous malformations are relatively rare benign vascular malformations. Patients may be asymptomatic or present with headache, seizure, hemorrhage, or neurologic deficits. We report 2 cases of patients with cavernomas in the third ventricle and at the foramen of Monro. We also performed a systematic review of the literature to examine the clinical features and efficacy of the current standard of care for these lesions.

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Is It Feasible to Treat Odontoid Fractures via Primary Posterior Reduction and Fixation without Fusion?  Voir?

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Delayed Retroclival and Cervical Spinal Subdural Hematoma Complicated by Preexisting Chiari Malformation in Adult Trauma Patient  Voir?

Traumatic spinal subdural hematoma involving the retroclival region and upper cervical spine is a rare pathology. To our knowledge, there have only been 2 prior cases in an adult trauma patient. We describe a patient with preexisting Chiari 1 malformation, who recently sustained a unilateral type 1 occipital condyle fracture with associated disruption of the tectorial membrane and transverse ligament, which returned with a retroclival subdural hematoma extending down to C7, causing spinal cord compression and symptomatic obstructive hydrocephalus.

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Kinase activity in recurring primary Skull Base Chordomas and Chondrosarcomas: identification of novel pathways of oncogenesis and potential drug targets  Voir?

Chordomas and chondrosarcomas are tumors that can occur in the skull base. Currently, 45% of chordomas and 56% of chondrosarcomas recur within five years of surgery. The role of adjuvant therapy is highly debated. No pharmacotherapies have been approved by the FDA for chordomas or chondrosarcomas. The high propensity for recurrence and lack of definitive adjuvant therapy necessitates additional basic science research to identify molecular anomalies associated with recurrent disease.

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Privacy, Confidentiality, and Security of Health Care Information: Lessons from the Recent WannaCry Cyberattack  Voir?

On 13 May, 2017 hackers started to spread a ransomware (a program that locks down all files in the infected system) to computers around the globe. According to the Europol, more than 200,000 computers in 150 countries have been victims of the cyberattack, which involved the request of a $300 ransom in order to return control of the encrypted files (Figure 1). The WannaCry ransomware took advantage of an inherent vulnerability of Microsoft Windows, which had already been previously explored by the U.S.

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Microsurgical Bypass Training Rat Model: Part 1 –Technical Nuances of Exposure of the Aorta and Iliac arteries  Voir?

Animal models using rodents are frequently used for the purpose of practicing microvascular anastomosis – an essential technique in cerebrovascular surgery. However, safely and efficiently exposing rat’s target vessels is technically difficult. Such difficulty may lead to excessive hemorrhage and shorten animal survival. This limits the ability to perform multiple anastomoses on a single animal and may increase the overall training time and costs. We report our model for microsurgical bypass training in rodents in two consecutive articles.

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Can We Make Still Easier Simple in Situ Decompression of the Ulnar Nerve at the Elbow?  Voir?

in situ decompression and transposition are equally effective in cubital tunnel syndrome treatment. Both are traditionally performed in the supine position.
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Face, content, and construct validity of an aneurysm clipping model using human placenta  Voir?

Proficient open surgical treatment of cerebral aneurysms requires extensive training and practice. The goal of this study was to test the validity of a human placenta aneurysm model for surgical simulation training of aneurysm clipping.
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Long-Term Outcomes of Mechanical Thrombectomy for Treatment of Acute Ischemic Stroke  Voir?

Ischemic stroke occurs in approximately 700,000 Americans each year, often resulting in either long-term disability or death.1 Significant efforts have been directed toward therapies for acute intervention including intravenous tissue plasminogen activator (tPA), which has been used in select patients since 1996.2 Despite interest in intra-arterial strategies, the role of mechanical thrombectomy for the treatment of acute ischemic stroke due to large vessel occlusion was only recently established by the publication of 6 major randomized controlled trials in 2015.

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Dawn of an Even Newer Era: Mechanical Thrombectomy for Acute Ischemic Stroke Beyond 6 to 8 Hours  Voir?

The publication of multiple high-quality trials in support of mechanical thrombectomy for large-vessel acute ischemic stroke in 2015 was received with much enthusiasm in the medical community and denoted the beginning of a new period in the care of this disease entity.1 Just about 2 years later we are again at the dawn of an even newer era: Mechanical thrombectomy beyond 6–8 hours from stroke onset. In May 2017, the results of the “Diffusion-Weighted Imaging (DWI) or Computed Tomography Perfusion Assessment with Clinical Mismatch in the Triage of Wake-Up and Late Presenting Strokes Undergoing Neurointervention” (DAWN) trial2 were presented at the European Stroke Organization Conference in Prague.

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A Bug in the Brain and the Future of Neurosciences  Voir?

Research into human brain activities, mainly into higher cortical functions, has exponentially increased in the past 2 decades. Cognitive and affective neuroscience are 2 fields that have benefitted the most from this inquiry. Actually, new disciplines such as neurosociology, neuroethics, and even neurotheology have emerged as a consequence of this effort to understand how the brain works to construct the essentials of what has been called humanity. Such achievement is mostly due to the use of functional magnetic resonance imaging (fMRI) as a tool for studying brain function in real time.

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Surgical Repair of Iatrogenic Transverse-Sigmoid Sinus Laceration with a Dural Flap During Skull Base Tumor Surgery: A Technical Case Report  Voir?

Injury to cerebral venous sinuses during craniotomy procedures can cause significant blood loss or venous air embolism potentially leading to serious morbidity or mortality. When iatrogenic sinus injuries occur, it is essential to promptly obtain hemostasis and repair the sinus defect.
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The Healthcare Landscape: Are Doctors Agents of Change or Impediments to Change?  Voir?

Lead, follow, or get out of the way!—Lee Iacocca (former head of Chrysler Motors)—Sometimes give your services for nothing, calling to mind a previous benefaction or present satisfaction. And if there be an opportunity of serving one who is a stranger in financial straits, give full assistance to all such. For where there is love of man, there is also love of the art.—Hippocrates, Precepts, Chapter 6—

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Publication Metrics in Neurosurgery  Voir?

Evolutionary changes in health care over the past 2 decades have dramatically altered the landscape of academic medicine. Increasing clinical responsibilities, constant documentation reminders, repeated retraining requirements, complex quality metrics, and relative value unit productivity targets are the parameters by which physicians are measured today. These strictures are ever-present and have a great impact on salary and reimbursement and frequently influence physician comportment. For academic physicians, there is 1 more aspect to address or be cognizant of: scholarly efforts in the form of teaching, lectures, research, and publications.

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Spinal arteriovenous malformation associated with Parkes Weber syndrome: Report of two cases and literature review  Voir?

To present two cases of Parkes Weber syndrome (PWS) with spinal arteriovenous malformation(AVM), and discuss the radiological features and clinical treatment with literature review.
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Newly Detected Cervical Spinal Dural Arteriovenous Fistula on Magnetic Resonance Angiography Causing Intracranial Subarachnoid Hemorrhage  Voir?

Although an asymptomatic spinal dural arteriovenous fistula (SDAVF) can sometimes be incidentally detected on magnetic resonance imaging (MRI), there are no previous reports showing the development of an SDAVF on MRI or magnetic resonance angiography (MRA).
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Endoscopic Removal of a Bullet That Migrated to the Third Ventricle Causing Hydrocephalus  Voir?

Hydrocephalus caused by an intraventricular bullet is a rare event. We report a case of endoscopic removal of an intraventricular bullet.
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Giant Bicompartmental Cystic Tentorial Schwannoma Mimicking a Meningioma  Voir?

Intracranial schwannomas most commonly arise from the vestibulocochlear nerve and less frequently from trigeminal, facial, and hypoglossal nerves. Intracranial schwannomas unrelated to cranial nerves are very rare; only approximately 50 cases have been reported in the literature. Tentorial schwannoma (TS) is even rarer, with only 13 cases reported to date. We present a rare case of giant TS.

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Protective functions of PJ34, a PARP inhibitor, is related to down-regulation of calpain and NF-κB in a mouse model of TBI  Voir?

Poly(ADP-ribose) polymerase (PARP), calpain, and nuclear factor-κB (NF-κB) are reported to participate in inflammatory reactions in pathological conditions and are involved in traumatic brain injury. The objective of this study was to investigate whether PARP participated in inflammation related to calpain and NF-κB in a mouse model of controlled cortical impact (CCI).

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Microsurgical Bypass Training Rat Model: Part 2 –Anastomosis Configurations  Voir?

Mastery of microsurgical anastomosis is key to achieving good outcomes in cerebrovascular bypass procedures. Animal models (especially rodents) provide an optimal pre-clinical bypass training platform. However, the existing models for practicing different anastomosis configurations have several limitations.

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Remote Lesions of Synchronous Sacral and Cervical Dural Arteriovenous Fistulas: A Case Report  Voir?

Spinal dural arteriovenous fistula (DAVF) is a rare disease, and multiple concurrent lesions are extremely rare. Such multiple spinal DAVFs have similar outflow routes at neighboring levels. However, there have been no reported cases of remote lesions of multiple spinal DAVFs. The authors herein report a case of double synchronous cervical and sacral DAVFs.

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Corrigendum to ‘Cost-Utility of Video-Electroencephalography Monitoring Followed by Surgery in Adults with Drug-Resistant Focal Epilepsy in Thailand’ [World Neurosurgery 98 (2017) 750-760]  Voir?

The authors regret that the above paper was printed with errors in the author affiliations. The correct affiliations are printed above.
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Corrigendum to ‘Does Size and Site Matter in Therapeutic Decompressive Craniectomy? A Laboratory-Based Experimental Study’ [World Neurosurgery 95 (2016) 441-446]  Voir?

The authors regret that the first author surname was misspelled as Miller where it should have been Millar.
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Corrigendum to ‘Predictors of Shunt Insertion in Aneurysmal Subarachnoid Hemorrhage’ [World Neurosurgery 98 (2017) 421-426]  Voir?

The authors regret that this article was published with an error in one of the author's names. The correct version is R. Shane Tubbs.
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Medulloblastoma with Atypical Dynamic Imaging Changes: Case Report with Literature Review  Voir?

We analyzed a case of medulloblastoma with atypical dynamic imaging changes retrospectively to summarize the atypical magnetic resonance imaging (MRI) features of medulloblastoma by reviewing the literature.
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Long-Standing Isolated Autoimmune Hypothalamitis Diagnosed with Endoscopic Transventricular Biopsy  Voir?

Autoimmune hypothalamitis, which is among the causes of acquired central diabetes insipidus, has seldom been described in the literature. This condition is probably provoked by the production of anti-vasopressin-secreting cell antibodies and antihypothalamus antibodies and is often associated with pituitary or polyendocrine autoimmunity. Correct diagnosis and immediate treatment are essential to avoid the progression of the pathologic process.

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Subarachnoid Hemorrhage Because of Distal Superior Cerebellar Artery Dissection in Neurofibromatosis Type 1  Voir?

Neurofibromatosis type 1 (NF1) is a rare disease with an incidence of 1 in every 3000 births. Numerous studies have focused on the main function of NF1 as a tumor suppressor, whereas few have examined the cerebrovascular abnormalities observed in patients with NF1. It is worth noting that intracranial aneurysms are uncommon in this condition.

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Multilevel ACDF with zero-profile devices: analysis of safety and feasibility, with a focus on sagittal alignment and its impact on clinical outcome. A single Institution experience and review of the literature  Voir?

In multilevel degenerative conditions posterior approaches are often preferred, but anterior approaches provide comparable clinical results and better alignment. Anterior plating entails higher rates of soft tissue injuries and dysphagia, particularly in multilevel cases.This study evaluates efficacy and safety of zero-profile devices in three and four-level ACDF, analyzing patients’ clinical and radiological long-term outcome.

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Obesity in Neurosurgery  Voir?

Obesity is an important consideration in neurosurgical practice. 28.3% of Australian adults are obese and it is estimated that over two-thirds of Australia’s population will be overweight or obese by 2025. This review of the effects of obesity on neurosurgical procedures demonstrated that, in patients undergoing spinal surgery, an increased BMI is a significant risk factor for surgical site infection, venous thromboembolism, major medical complications, prolonged length of surgery and increased financial cost.

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“On the Spot”: The Use of Four-Dimensional Computed Tomography Angiography to Differentiate a True Spot Sign From a Distal Intracranial Aneurysm  Voir?

Spontaneous intracerebral hemorrhage may arise from underlying abnormalities, including aneurysms. Computed tomography angiography (CTA) is widely used for the detection of possible underlying causes, which is important because it may have immediate therapeutic consequences. In addition, CTA is used to detect the so-called spot sign, indicating active hemorrhage, which carries a worse prognosis. However, CTA is a snapshot in time. Four-dimensional (4D) CTA is a dynamic type of imaging and has emerged as a valuable imaging technique for different neurovascular disorders.

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Delayed Brainstem Hemorrhage Secondary to Mild Traumatic Head Injury: Report of Case with Good Recovery  Voir?

In clinical practice, secondary traumatic brainstem hemorrhage often develops during descending transtentorial herniation due to raised intracranial pressure, which is known as Duret hemorrhage.Although usually considered a fatal and irreversible event, in rare circumstances, victims of Duret hemorrhage could gain favorable outcomes.To our knowledge, secondary brainstem hemorrhage due to mild traumatic head injury without descending transtentorial herniation has never been reported. In this report, we present a case of delayed brainstem hemorrhage secondary to a relatively mild traumatic brain injury that experienced a rapid and favorable recovery.

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Intracranial Hypotension Following Traumatic Brain Injury: A Diagnostic and Therapeutic Challenge  Voir?

Intracranial hypotension (IH) is a recognized cause of coma; however, the diagnosis is often challenging, especially in patients with superimposed traumatic brain injury.
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A Case of Laterally Extended High-Positioned Chordoma Treated Using the High Cervical Retropharyngeal Approach  Voir?

Several surgical approaches for the treatment of pathologies of the craniovertebral junction (CVJ) and high cervical regions have been reported. For the best postoperative results, selection of a surgical route to treat such pathologies should be based on a complete understanding of the approach.
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Impact of Gradient Number and Voxel Size on Diffusion Tensor Imaging Tractography for Resective Brain Surgery  Voir?

To explore quantitatively and qualitatively how the number of gradient directions (NGD) and spatial resolution (SR) affect diffusion tensor imaging (DTI) tractography in patients planned for brain tumor surgery, using routine clinical magnetic resonance imaging protocols.
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“Outside Support”: Curious Case of Duplicated Posterior Elements  Voir?

An 18-month-old male child was referred to our radiology department for imaging of a hard midline bony protuberance. On clinical examination the swelling was bony hard and not tender. Excoriations were seen on the overlying skin. Computed tomography and magnetic resonance imaging of the spine revealed heterotopic bone formation in the subcutaneous fat of the midline lumbar region (Figures 1 and 2). This well-formed corticated bone showed normal fatty marrow within it. The spinal cord was at its normal level for age without any tethering.

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Case of Familial Moyamoya Disease Presenting 10 Years After Initial Negative Magnetic Resonance Screening in Childhood  Voir?

Both genetic and environmental factors are considered to contribute to the onset of moyamoya disease, but the exact mechanism has not yet been clarified. Furthermore, the typical time course of progression to vessel occlusion has not been established, even in the genetically high-risk population.
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Was Cavum Septum Pellucidum the Cause of Intractable Seizure in a 17-Year-Old Boy with Wilson Disease?  Voir?

Cavum septum pellucidum (CSP), which is often found incidentally in a few populations, occasionally becomes symptomatic if enlarged significantly. Wilson disease (WD) is an uncommon autosomal recessive inborn defect in copper metabolism characterized by abnormal accumulation of copper in various tissues, particularly in the liver and the brain. Seizure disorder, although rare both in CSP and WD, may happen in a few patients with either of the conditions.

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Dynamic Four-Dimensional Computed Tomography Angiography for Neurovascular Pathologies  Voir?

This article illustrates, summarizes, and reviews the multifaceted application of four-dimensional (4D) computed tomography angiography (CTA) in the characterization and diagnosis of various cerebrovascular and tumor-associated vascular pathologies through the presentation of clinical cases, including acute and chronic stroke, arteriovenous malformations, aneurysm, moyamoya disease, and hypervascularity associated with a tumor and its relationship to preoperative embolization. The technical nuances and limitations of the 4D-CTA technique are also discussed.

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http://www.worldneurosurgery.org/article/S1878-8750(17)30407-2/fulltext?rss=yes

The Greenberg Rapid Review was developed to assist neurosurgical residents and fully practicing neurosurgeons as a fast and easy-to-use review book in conjunction with the original Greenberg Handbook of Neurosurgery. The review uses a combination of different question formats, clinical pearls, and mnemonic devices, allowing readers a way to quiz themselves about specific topics within neurosurgery, neurology, neuroradiology, neuropathology, and critical care quickly.

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A Case of Ecchordosis Physaliphora in the Prepontine Cistern: A Rare Entity in the Differential Diagnosis of an Epidermoid Cyst  Voir?

Ecchordosis physaliphora (EP) is a benign notochordal remnant that is usually asymptomatic. We report a case of a symptomatic large EP mimicking an epidermoid cyst.
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Radiation-Induced Malignant Peripheral Nerve Sheath Tumors: A Systematic Review  Voir?

Radiation-induced malignant peripheral nerve sheath tumors (MPNSTs) are an uncommon late risk of irradiation. We conducted the largest systematic review to date of individual patient data for patients with these tumors.
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Spontaneous Regression of a Hypoglossal Neurinoma: Case Report and Review of the Literature  Voir?

Hypoglossal neurinomas are very rare intracranial tumors. The management choices include surgery, as the gold standard, and radiosurgery or a combination of both. Little is known about this condition and the behavior of this tumor.
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Hereditary Multiple Cerebral Cavernous Malformations Associated with Wilson Disease and Multiple Lipomatosis  Voir?

We report on a patient with 2 Mendelian diseases—symptomatic multiple familial cerebral cavernous malformations (FCCMs) and Wilson disease. Genetic analysis revealed single nucleotide polymorphisms in genes CCM2 and CCM3, associated with cavernous malformations, and homozygote mutation in the ATP7B gene, responsible for Wilson disease. FCCMs were symptomatic in 3 generations. The patient also had multiple lipomatosis, which is suggested to be a familial syndrome.In recent years there has been an increasing amount of publications linking FCCMs with other pathology, predominantly with extracranial and intracranial mesenchymal anomalies.

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Successful Hybrid Neurovascular Surgery for a Ruptured Basilar Artery Dissecting Aneurysm in a Patient with Jeopardized Collateral Circulation Associated with Aortitis Syndrome  Voir?

Dissecting aneurysms of the basilar artery (BA) are rare lesions, and the management of them has been controversial and challenging. The treatment becomes much more difficult when the patient has a disorder such as aortitis syndrome, which makes cerebral arteries occluded and tortuous. We describe a case of a ruptured BA dissecting aneurysm associated with aortitis syndrome, successfully treated with hybrid neurovascular surgery.

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Corrigendum to: ‘Preoperative Volumetric Assessment Matched with High-Field Intraoperative Magnetic Resonance Imaging-Guided Stereotactic Evacuation of Brain Abscesses’ [World Neurosurg. 91 (2016) 238-244]  Voir?

The authors regret that the incorrect affiliation of co-author Prof. Alessandro Frati was printed in this issue, the correct affiliation is “IRCCS “Neuromed” Neurosurgery, Pozzilli (IS), Italy.” The authors would like to apologize for any inconvenience caused.
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Ruptured Distal Anterior Choroidal Artery Aneurysm Treated with Superselective Provocative Testing and Coil Embolization  Voir?

Aneurysms of the anterior choroidal artery are uncommon, and distal anterior choroidal artery aneurysms are even rarer, with only 34 cases reported in the medical literature. These lesions have been most commonly reported in association with moyamoya disease or arteriovenous malformations. Most published experience with these aneurysms involves open surgical approaches. Reports of endovascular treatment have been in patients with lesions distal to the plexal point and have employed vessel occlusion with liquid embolic agents in preference to coil embolization.

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Cross-Modal Recruitment of Auditory and Orofacial Areas During Sign Language in a Deaf Subject  Voir?

Modern sign languages used by deaf people are fully expressive, natural human languages that are perceived visually and produced manually. The literature contains little data concerning human brain organization in conditions of deficient sensory information such as deafness.
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Primary Spinal Intramedullary Neurocysticercosis: A Report of 3 Cases  Voir?

We describe a series of 3 cases of the rare intramedullary form of primary spinal neurocysticercosis. The cases were seen in varied age groups and showed different profiles at presentation. All the cases were thoroughly evaluated clinically and radiologically. Serologic tests were not conducted. In all cases, magnetic resonance imaging showed a large intramedullary lesion in the thoracic spinal cord consisting of a cystic lesion with a well-defined intramural nodule. One case was managed with steroids and cysticidal therapy, a second case was managed with steroids and surgery (2 emergency procedures), while the third case was managed without any medical or surgical intervention, as the patient was unwilling for either.

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Predatory Publishing and Academic Integrity  Voir?

Although the increase in article retraction has been discussed extensively within various academic circles, there has been little-to-no investigation regarding how this trend has specifically affected the field of neurosurgery. In “Retraction of Neurosurgical Publications: A Systematic Review,” Wang et al. address in clear, quantifiable terms, how this issue has manifested itself within our discipline. Although their findings and recommendations could certainly assist neurosurgical departments in strengthening their scholarly output, it might also be prudent to explore some of the observations and tools other disciplines have reported regarding topics pertinent to article retraction.

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Xanthomatous Hypophysitis Presenting with Diabetes Insipidus Completely Cured Through Transsphenoidal Surgery: Case Report and Literature Review  Voir?

Xanthomatous hypophysitis (XH) is extremely rare. Only 27 cases have been reported in the literature. No XH patient presenting with diabetes insipidus (DI) has been completely cured through surgery. Here, we describe the first XH case of a DI patient whose pituitary function was normalized postoperatively, without hormone replacement therapy.

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Spinal Cord Compression Secondary to Epidural Fibrosis Associated with Percutaneously Placed Spinal Cord Stimulation Electrodes: Case Report and Review of the Literature  Voir?

Spinal cord stimulation is a safe method for treating chronic pain syndromes. Spinal cord stimulators can be placed either surgically by creating a laminectomy defect for paddle leads or percutaneously by inserting electrodes. They are usually not associated with major complications. There have been several reports of epidural fibrosis formation after paddle lead placement but only 1 case of excessive fibrosis following percutaneous lead placement. We describe the unique case of excessive cervical fibrosis formation with creation of tolerance phenomenon, clinically significant stenosis, cord compression, and myelopathy after percutaneous lead placement, which improved after surgical removal of the implant.

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Functional Connectivity in Frontoparietal Network: Indicator of Preoperative Cognitive Function and Cognitive Outcome Following Surgery in Patients with Glioma  Voir?

Patients with diffuse glioma are known to have impaired cognitive functions preoperatively. However, the mechanism of these cognitive deficits remains unclear. Resting-state functional connectivity in the frontoparietal network (FPN) is associated with cognitive performance in healthy subjects. For this reason, it was hypothesized that functional connectivity of the FPN would be related to cognitive functioning in patients with glioma. To assess this relationship, preoperative cognitive status was correlated to patient-specific connectivity within the FPN.

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A retrospective study of clinical outcomes after endovascular treatment in acute ischemic stroke patients with complete anterior circulation infarction (TACI) in the absence of multimodal CT  Voir?

To analyze the positive predictive value of large artery occlusion and clinical prognosis in acute ischemic stroke patients with total anterior circulation infarct (TACI) who underwent endovascular treatment in the absence of multimodal CT angiography (CTA)/ CT perfusion (CTP).
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Vertebrobasilar Insufficiency Due to Distal Posterior Inferior Cerebellar Artery Compression in Chiari 1.5  Voir?

Chiari malformation is characterized by radiographic evidence of herniation of cerebellar tonsils below the foramen magnum and a symptom complex of headaches; breathing, swallowing, or sleep difficulties; ataxia; restless; and motor and/or sensory deficits.
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http://www.worldneurosurgery.org/article/S1878-8750(17)30633-2/fulltext?rss=yes

It was in the early 1990s at Northwestern; I was a medical student looking for a career path and had become enamored but uncertain about the field of neurosurgery. Dr. Hunt Batjer had not yet arrived to Northwestern, and I was seeking mentors. It was at that time that I first became aware of Dr. Ivan Ciric. He was a towering figure known for humble yet sharp elegance, which pervaded his demeanor, techniques, patient encounters, and teaching style. At the time, he was chair of the neurosurgery division at Evanston Hospital, which had a teaching association with Northwestern.

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Hemimasticatory Spasm with a Single Venous Compression Treated with Microvascular Decompression of the Trigeminal Motor Rootlet  Voir?

Hemimasticatory spasm is a very rare disorder of the trigeminal motor rootlet that is characterized by a paroxysmal involuntary contraction of the jaw-closing muscles. The mechanisms for hemimasticatory spasm remain unclear, and an efficient treatment strategy still needs to be developed.
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Reconstruction of Thoracic Spine Using a Personalized 3D-Printed Vertebral Body in Adolescent with T9 Primary Bone Tumor  Voir?

Neurosurgery and spine surgery have the potential to benefit from the use of 3-dimensional printing (3DP) technology due to complex anatomic considerations and the delicate nature of surrounding structures. We report a procedure that uses a 3D-printed titanium T9 vertebral body implant post T9 vertebrectomy for a primary bone tumor.

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Safety and Efficacy of Antibacterial Prophylaxis After Craniotomy: A Decision Model Analysis  Voir?

Antibiotic prophylaxis has revolutionized the safety of neurosurgical procedures in the last century. Today, the clinician's drug of choice before surgery often is based on the antibiotic's resistance profile and drug-induced complications.
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Prenatal Diagnosis and Multimodal Neonatal Treatment of a Rare Pial Arteriovenous Fistula: Case Report and Review of the Literature  Voir?

Intracranial pial arteriovenous fistulas (PAVFs) are direct communications between the arterial and venous system of the brain, with the characteristic absence of a plexiform nidus, as seen in the classic cerebral arteriovenous malformations. These vascular malformations, usually occurring in the pediatric population, very rarely are diagnosed in utero, because of a lack of understanding of the condition and because they may be hard to visualize.

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Status Epilepticus Secondary to Pseudonodular Hemorragic Occipital Lesion with Edema: “Non Semper Ea Sunt, Quae Videntur, Decipit Frons Prima Multos” (Things Are Not Always What They Seem; The First Appearance Deceives Many)  Voir?

We report a case in which common radiologic images masked a rare case of supratentorial hemangioblastoma (HBL). Other peculiarities of this case are the clinical presentation with status epilepticus and the occurrence of a supratentorial HBL unrelated to von Hippel–Lindau syndrome. Based on clinical and radiologic findings, including massive cerebral edema and hemorrhagic presentation, our preoperative diagnosis was a cerebral metastasis. In this scenario, physicians must take into account the words of the Roman fabulist Phaedrus: “Non semper ea sunt, quae videntur, decipit frons prima multos” (things are not always what they seem; the first appearance deceives many).

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Magnetic Resonance Spectroscopy Findings in Patients with Dural Arteriovenous Fistulas: Three Case Reports  Voir?

Magnetic resonance spectroscopy (MRS) is a potentially useful modality for evaluating brain metabolites in patients with dural arteriovenous fistula (dAVF). Here we describe a different pattern of MRS-based cerebral metabolism findings in patients with dAVF.
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Impact of Prehospital Transportation on Survival in Skiers and Snowboarders with Traumatic Brain Injury  Voir?

Prehospital helicopter use and its impact on outcomes in snowboarders and skiers incurring traumatic brain injury (TBI) is unknown. The present study investigates the association of helicopter transport with survival of snowboarders and skiers with TBI, in comparison with ground emergency medical services (EMS), by using data derived from the National Trauma Data Bank (2007–2014).

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Computed Tomography and Magnetic Resonance Imaging Parameters Associated with Poor Clinical Outcome in Spondylodiscitis  Voir?

Prognostic factors for the disease course of patients with spondylodiscitis have not been well studied.
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Superior Petrosal Vein Sacrifice During Microvascular Decompression: Perioperative Complication Rates and Comparison with Venous Preservation  Voir?

To investigate potential effect of sacrifice of the superior petrosal vein (SPV) on postoperative complications after microvascular decompression (MVD).
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Primary Pituitary Fibrosarcoma with Previous Adenoma  Voir?

Pituitary sarcomas are rare clinical entities most often encountered as secondary neoplasms representing late sequelae of radiation therapy to the sellar region. Primary pituitary fibrosarcomas (PPFS), in contrast, are exceptionally rare tumors with very few cases described in the literature thus far. Herein, we present a case of PFFS and describe it in the context of the existing literature.

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Natural History of Intracranial Absorbable Gelatin Powder  Voir?

This case report documents the natural history of intracranial absorbable gelatin powder. We depict the serial imaging of Surgifoam in the cavity of an intracranial hemorrhage cavity after surgical evacuation.
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Association of Different Stenting Procedures with Symptomatic Thromboembolic Complications in Stent-Assisted Coiling of Ruptured Wide-Necked Intracranial Aneurysms  Voir?

This study aimed to evaluate the association of different stenting procedures with the procedure-related complications in stent-assisted coiling (SAC) of ruptured wide-necked aneurysms.
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Analysis of Prognostic Factors, Survival Rates, and Treatment in Anaplastic Hemangiopericytoma  Voir?

In this study, we aimed to identify prognostic factors in anaplastic hemangiopericytoma (AHPC) and clinical behaviors that differentiate primary and secondary AHPC.
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Dumbbell-Shape Hydatid Cyst of Meckel Cave Extending to Cerebellopontine Angle and Middle Fossa; Surgical Technique and Outcome of Rare Case  Voir?

Cerebral hydatid cyst is among the rare presentations of echinococcosis. Almost all the reported cases of intracranial hydatid cysts are in the cortical regions (parietal lobe in the territory of the middle cerebral artery), and all have been removed surgically using the water jet dissection technique. However, in locations in which there are several neuronal structures, such as the cerebellopontine angle, this method might not be applicable.

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A New Sling Technique in Cervical Radiculopathy Caused by Vertebral Artery Loop Compression  Voir?

A 52-year-old woman had a 20-month history of progressive radiating pain in the left arm and numbness on C7 dermatome.
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A Novel Tool for Deformity Surgery Planning: Determining the Magnitude of Lordotic Correction Required to Achieve a Desired Sagittal Vertical Axis  Voir?

We sought to create a model capable of predicting the magnitude of pelvic incidence–lumbar lordosis (PI-LL) correction necessary to achieve a desired change in sagittal vertical axis (SVA).
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Formulation of a Three-Tier Cisternal Grade as a Predictor of In-Hospital Outcome from a Prospective Study of Patients with Traumatic Intracranial Hematoma  Voir?

Outcome prediction is of paramount importance in traumatic brain injury. Our objective of conducting this prospective study was to identify the predictors needed to formulate a prognostic score.
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Industry Funding for Neurosurgery Research  Voir?

The role of industry in funding medical research and innovation is not new. For decades it has had a strong positive influence on research and adoption of new technologies, publication of articles, career development of individuals, and the overall advancement of a particular discipline or field.1 It engenders partnerships between institutions and collaborations between individual physicians and scientists, is a strong source of funding support for educational activities, and buoys fledgling research endeavors at institutions without a large research infrastructure.

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Treatment of Moyamoya Disease and Unruptured Intracranial Aneurysm in Floating-Harbor Syndrome  Voir?

This is the first report of the successful treatment of moyamoya disease and an unruptured intracranial aneurysm in a patient with Floating-Harbor syndrome.
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Maximizing Interhospital Transfer Resources for Neurosurgical Patients  Voir?

Delays in patient transfers are associated with worse outcomes for some neurosurgical conditions. One of the primary causes of transfer delay is lack of neurosurgery intensive care unit bed availability. In the present study, we characterize the results of implementing an interhospital transfer protocol to reduce unnecessary transfers and improve bed availability.

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Ten-Year Retrospective Study on the Management of Spinal Arteriovenous Lesions: Efficacy of a Combination of Intraoperative Digital Subtraction Angiography and Intraarterial Dye Injection  Voir?

The goal of treatment for spinal arteriovenous lesions is to completely obliterate the shunt. In our institution, intraoperative digital subtraction angiography and intraarterial injection of contrast agent have been used to accurately identify the site of arteriovenous shunts. We describe the intraoperative digital subtraction angiography and intraarterial dye injection procedures and how they may improve surgical outcomes.

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The Role of the Features of Facet Joint Angle in the Development of Isthmic Spondylolisthesis in Young Male Patients with L5-S1 Isthmic Spondylolisthesis  Voir?

To investigate facet tropism and its role in development of lumbar isthmic spondylolisthesis (IS) in young men.
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Cauda Equina Syndrome Due To Dural Sac Shift with Engorgement of the Epidural Venous Plexus: Rare Complication After Lumbar Microdiscectomy  Voir?

Several postoperative complications related to lumbar microdiscectomy have been reported, including cauda equina syndrome. However, to the best of our knowledge, postoperative cauda equina syndrome resulting from dural sac shift with engorgement of the epidural venous plexus is yet to be reported.
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Local Anesthesia for Endovascular Treatment of Unruptured Intracranial Aneurysms: Feasibility, Safety, and Periprocedural Complications  Voir?

The aim of the study is to report the feasibility, safety, and outcomes associated with endovascular treatment (EVT) of unruptured intracranial aneurysms (UIAs) under local anesthesia.
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Prognostic Factors for Recovery After Anterior Debridement/Bone Grafting and Posterior Instrumentation for Lumbar Spinal Tuberculosis  Voir?

Anterior debridement/bone grafting/posterior instrumentation is a common selection for the treatment of lumbar spinal tuberculosis (LST). To date, no study has focused on the prognostic factors for recovery after this surgery.
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Posterior Bilateral Intermuscular Approach for Upper Cervical Spine Injuries  Voir?

To investigate a novel intermuscular surgical approach for posterior upper cervical spine fixation.
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Neurosurgical Training: A Process, Not an Event  Voir?

It is not the strongest of the species that survives, nor the most intelligent, but the one most responsive to change.—Charles Darwin
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Analysis of Delayed Intracerebral Hemorrhage Associated with Deep Brain Stimulation Surgery  Voir?

Deep brain stimulation (DBS) may cause various complications including intracerebral hemorrhage (ICH). Because ICH causes devastating neurologic outcomes, various surgical techniques are attempting to reduce the chances of ICH. More importantly, early detection and proper management of postoperative ICH are indispensable. ICH may occur immediately or delayed following DBS; in this study, we analyzed the clinical features of delayed ICH after DBS.

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Image-Guided Lateral Mass Osteotomy for En Bloc Resection of Cervical Ewing Sarcoma: A Technical Note  Voir?

En bloc resection of Ewing sarcoma in the cervical spine according to Enneking's principles is technically challenging owing to the proximity of important neurovascular structures, the complex local anatomy, and the biomechanical instability of radical resection. The rarity of Ewing sarcoma and variability of its presentation justifies ongoing exploration and compilation of the surgical nuances and subtleties of en bloc resection in the cervical spine.

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First Report of Coexistence of Two Ectopic Pituitary Tumors: Rathke Cleft Cyst and Silent Adrenocorticotropic Hormone Adenoma  Voir?

Rathke cleft cysts (RCCs) and pituitary adenomas (PAs) are thought to have a common embryonic ancestry; however, PAs with a concomitant RCC inside the sella turcica are rarely observed. Ectopic pituitary tumors are also rare.
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Penetrating Bihemispheric Traumatic Brain Injury: A Collective Review of Gunshot Wounds to the Head  Voir?

Head injuries that cross midline structures of the brain are bihemispheric. Other terms have been used to describe such injuries, but bihemispheric is the most accurate and should be standard nomenclature. Bihemispheric head injuries are associated with greater mortality and morbidity than other penetrating traumatic brain injuries (TBIs). Currently, there is a tendency to manage severe gunshot wounds (GSWs) to the head nonoperatively, despite reports of improved outcome in military patients treated aggressively.

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Choreatic Side Effects of Deep Brain Stimulation of the Anteromedial Subthalamic Nucleus for Treatment-Resistant Obsessive-Compulsive disorder  Voir?

Patients with treatment-resistant obsessive-compulsive disorder (OCD) are potential candidates for deep brain stimulation (DBS). The anteromedial subthalamic nucleus (STN) is among the most commonly used targets for DBS in OCD.
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Radiation-Induced Schwannomas and Neurofibromas: A Systematic Review  Voir?

Radiation-induced benign peripheral nerve sheath tumors are uncommon late complications of irradiation. We conducted the largest systematic review of individual patient data.
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Altmetrics in Scientific Research: Flash in the Pan or Transformative Innovation?  Voir?

In the beginning, there was the curriculum vitae, listing all a scholar's academic and professional work. Publications in peer-reviewed professional journals were the most influential factor in the curriculum vitae for judging scholarly accomplishment and merit and the key to academic advancement, tenure, and future research funding for publications to further swell the curriculum vitae volume. Individual scholars labored over a career to assemble an impressive personal compendium of publications, which stood as proof of scientific accomplishment.

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Endoscopic endonasal resection of a mixedlesion of gangliocytoma and non-functioning pituitary adenoma  Voir?

The coexistence of a gangliocytoma and a pituitary adenoma is a rare event, which has only been studied in case reports previously. The knowledge of its diagnosis and treatment is extremely limited.
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The Safety and Efficiency of PVCR without Anterior Support Applied in Treatment of Yang Type A Severe Thoracic Kyphoscoliosis  Voir?

To assess the clinical and radiographic outcomes of posterior vertebral column resection (PVCR) without anterior support in treatment of Yang type A severe rigid thoracic kyphoscoliosis.
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Lateral Transpsoas Approach to the Lumbar Spine and Relationship of the Ureter: Anatomic Study with Application to Minimizing Complications  Voir?

Complications from lateral lumbar interbody fusion procedures range from neurologic deficits to organ and blood vessel injuries. Injury to the ureter has been reported though uncommon. The present study was performed to elucidate the anatomic relationship of the ureter to this surgical approach.
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Subarachnoid Hemorrhage in Germany Between 2010 and 2013: Estimated Incidence Rates Based on a Nationwide Hospital Discharge Registry  Voir?

Nordic countries are the primary source for nationwide data on the incidence of subarachnoid hemorrhage (SAH). Reliable estimates of national incidence rates of SAH in other countries are lacking, yet studies from Nordic countries with exceptional incidence rates are sometimes disregarded because of concerns regarding external validity. Autopsies are rarely performed for sudden deaths; therefore, estimates of the SAH incidence commonly reflect the hospital discharge rates. Our aim was to estimate the nationwide incidence of nontraumatic SAH in Germany using a national hospital discharge register.

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Novel Anatomic Classification of Spontaneous Thalamic Hemorrhage Classified by Vascular Territory of Thalamus  Voir?

Spontaneous thalamic hemorrhage has increased in incidence in recent years. Analysis of the characteristics of thalamic hemorrhage was based on the vascular territories of the thalamus.
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Gamma Knife Radiosurgery for Idiopathic Trigeminal Neuralgia: Does the Status of Offending Vessels Influence Pain Control or Side Effects?  Voir?

To evaluate pain control and side effects after gamma knife radiosurgery (GKRS) for classical idiopathic trigeminal neuralgia (TN) with or without neurovascular compression (NVC).
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Nerve Atrophy and a Small Trigeminal Pontine Angle in Primary Trigeminal Neuralgia: A Morphometric Magnetic Resonance Imaging Study  Voir?

To prospectively evaluate the morphological and structural changes in the trigeminal nerve in patients with trigeminal neuralgia (TN) compared with healthy controls.
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The Subcostal Nerve During Lateral Approaches to the Lumbar Spine: An Anatomical Study with Relevance for Injury Avoidance and Postoperative Complications Such as Abdominal Wall Hernia  Voir?

Lateral approaches to the spine are increasing in popularity. However, details of the innervation pattern of the abdominal oblique muscles with the initial dissection have not been well studied.
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Awake Craniotomy Anesthesia: A Comparison of the Monitored Anesthesia Care and Asleep-Awake-Asleep Techniques  Voir?

Commonly used sedation techniques for an awake craniotomy include monitored anesthesia care (MAC), using an unprotected airway, and the asleep-awake-asleep (AAA) technique, using a partially or totally protected airway. We present a comparative analysis of the MAC and AAA techniques, evaluating anesthetic management, perioperative outcomes, and complications in a consecutive series of patients undergoing the removal of an eloquent brain lesion.

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Endoscopic Third Ventriculostomy: Outcome Analysis of an Anterior Entry Point  Voir?

Endoscopic third ventriculostomy (ETV) is a safe and effective treatment for hydrocephalus. An entry point located 4 cm anterior to the coronal suture, 3 cm anterior to Kocher point, and approximately 9 cm from the pupil at the midpupillary line has been used successfully for the last 20 years in our center. We aimed to evaluate this alternative anterior entry point routinely used for ETV, with or without concurrent endoscopic biopsy.

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Prevention of Thromboembolic Complications After Spine Surgery by the Use of Low-Molecular-Weight Heparin  Voir?

This study aimed to evaluate the effectiveness and safety of the use of low-molecular-weight heparin (LMWH) in the prevention of thromboembolic complications after spine surgery.
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Microsurgical Clipping of an Unruptured Carotid Cave Aneurysm: 3-Dimensional Operative Video  Voir?

Most aneurysms originating from the clinoidal segment of the internal carotid artery (ICA) are nowadays managed conservatively, treated endovascularly with coiling (with or without stenting) or flow diverters. However, microsurgical clip occlusion remains an alternative. This video demonstrates clip occlusion of an unruptured right carotid cave aneurysm measuring 7 mm in a 39-year-old woman. The patient opted for surgery because of concerns about prolonged antiplatelet use associated with endovascular therapy.

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Unusual Intraparenchymal Pontomedullary Epidermoid Cyst in a 2-Year-Old Child: A Case Report and Review of the Literature  Voir?

Intrinsic brainstem epidermoid cysts are rare, benign, slow-growing lesions. Their eloquence precludes complete excision; however, subtotal resection often will result in prolonged or sometimes permanent relief of presenting symptoms and signs. We describe an unusual case and review the literature of this pathology in the pediatric population.

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Optic Canal Decompression: Comparison of 2 Surgical Techniques  Voir?

The optic canal is a bony channel that connects the anterior cranial fossa and orbit and contains the optic nerve and ophthalmic artery. It can be affected by several pathologies, leading to compression of the nerve nearby or inside the canal, leading to visual impairment. The usual technique to decompress the canal is through a craniotomy, but recently endoscopic endonasal approaches (EEAs) have surfaced as an interesting alternative due to direct access to the canal without the need for manipulation of neurovascular structures.

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Planning and Executing the Neurosurgery Boot Camp: The Bolivia Experience  Voir?

The neurosurgical boot camp has been fully incorporated into U.S. postgraduate education. This is the first implementation of the neurosurgical boot in a developing country. To advance neurosurgical education, we developed a similar boot camp program, in collaboration with Bolivian neurosurgeons, to determine its feasibility and effectiveness in an international setting.

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Zero-Profile Spacer Versus Cage-Plate Construct in Anterior Cervical Diskectomy and Fusion for Multilevel Cervical Spondylotic Myelopathy: Systematic Review and Meta-Analysis  Voir?

Anterior cervical diskectomy and fusion with plate-screw construct has been gradually applied for multilevel cervical spondylotic myelopathy in recent years. However, long cervical plate was associated with complications including breakage or loosening of plate and screws, trachea-esophageal injury, neurovascular injury, and postoperative dysphagia. To reduce these complications, the zero-profile spacer has been introduced. This meta-analysis was performed to compare the clinical and radiologic outcomes of zero-profile spacer versus cage-plate construct for the treatment of multilevel cervical spondylotic myelopathy.

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Has “Publish or Perish” Become “Publish and Payment”? Navigating Neurosurgical Research in an Innovative Industry  Voir?

“Neurosurgery has become a technology-intensive surgical subspecialty.”1 These words, spoken by Robertson1 in his 2008 address at the Annual Meeting of the American Association of Neurological Surgeons, become more relevant with each passing year. Neurosurgery subspecialties, including spine, functional and epilepsy, neuro-oncology, and cerebrovascular, continue to make great strides in treating difficult diseases but are powered, in great part, by industry-provided technology. In this setting of continuous collaborations with industry partners, neurosurgeons are particularly vulnerable to ethical issues of financial conflict of interest (COI).

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Cerebral Aneurysm Clipping/Coiling 101  Voir?

In the article by Piazza et al.1 recently published in WORLD NEUROSURGERY, the authors performed an analysis of the National Inpatient Sample to estimate the number of intracranial aneurysms (ruptured and unruptured) treated using clipping or endovascular modalities over a 10-year period (2002–2011) at teaching institutions. Additional data mining from the National Inpatient Sample was used to study the opportunities available to residents to partake in these procedures, calculated as the number of a specific type of case divided by average number of residents during a given year.

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Iatrogenic Sigmoid Sinus Occlusion Rescued by Graft Repair and Endovascular Thrombolysis  Voir?

Iatrogenic cerebral venous sinus injury and occlusion may occur during resection of parasagittal meningioma and lateral skull base surgery. The former involves the superior sagittal sinus, and direct surgical repair is associated with good results. Outcome of direct repair of transverse–sigmoid sinus injury is less clear. We present a patient with iatrogenic sigmoid sinus injury in whom direct repair was complicated by subsequent thrombosis that was successfully salvaged by combined endovascular mechanical and chemical thrombolysis.

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Clipping Versus Coiling in Anterior Circulation Ruptured Intracranial Aneurysms: A Meta-Analysis  Voir?

To evaluate open surgical versus endovascular repair of anterior circulation ruptured intracranial aneurysms based on operative mortality, permanent neurologic deficit, late mortality, and need for reintervention.
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Simple Tumor Localization Scale for Estimating Management Outcome of Intracranial Meningioma  Voir?

Intracranial meningiomas are typically benign extracerebral tumors derived from dural arachnoid cells. Predominantly, these tumors are effectively managed surgically, but the prognosis is heavily dependent on a tumor's histologic heterogeneity and its location. It is known that reproductive and hormonal factors increase the risk for meningioma in adult females, but their prognostic value still remains controversial.This study's aim was to examine possible correlation between tumor location and outcome, as well as to evaluate the prognostic value of the proposed simple tumor localization scale in predicting the management outcome of intracranial meningioma.

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Radiological Study of the Carotid-Clival Window and Its Application in Endoscopic Endonasal Expanded Approaches  Voir?

The surgical approach to the petrous apex (PA) and petroclival junction (PCJ) remains a challenge. The carotid-clival window (CCW) represents the widest window available to approach the PCJ from a mediolateral endoscopic route. Here we define the CCW radiologically in nonpathological conditions, to establish the anatomic variability of the PCJ, relate this variability to pneumatization patterns, and evaluate some technical concerns conditioned by the CCW.

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Somatosensory Evoked Potentials During Temporary Arterial Occlusion for Intracranial Aneurysm Surgery: Predictive Value for Perioperative Stroke  Voir?

Temporary arterial occlusion (TAO) is valuable for minimizing intraoperative rupture risk during intracranial aneurysm microsurgery; however, it may be associated with ischemic injury. This study aims to identify surgical and intraoperative neurophysiologic monitoring factors that predict perioperative stroke risk after TAO.

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Elimination of Subsidence with 26-mm-Wide Cages in Extreme Lateral Interbody Fusion  Voir?

Extreme lateral interbody fusion (ELIF) has gained popularity as a minimally invasive technique for indirect decompression. However, graft subsidence potentially threatens long-term success of ELIF. This study evaluated whether 26-mm-wide cages can eliminate subsidence and subsequent loss of decompression in ELIF.

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Carotid-Falciform Optic Neuropathy: Microsurgical Treatment  Voir?

Several recent reports have implicated vascular ectasia and vessel contact in dysfunction of the visual apparatus. A subset of patients with prechiasmatic visual deterioration have an ectatic internal carotid artery (ICA) that displaces and flattens the optic nerve (ON) rostrally as the ON exits the skull base. We describe a proposed pathophysiologic mechanism and a straightforward surgical technique for dealing with this problem.

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Brain Abscess After Halo Fixation for the Cervical Spine  Voir?

Halo fixation is one of the possible treatments for cervical spine fractures. However, improper use of these devices may lead to many complications, such as pin loosening, halo dislocation, pin site infection, and intradural penetration.
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Cranium bifidum occultum associated with hypertelorism treated with posterior vault reconstruction and orbital box osteotomies: Case report and technical note  Voir?

Cranium bifidum occultum is a disorder of skull ossification presenting as an enlarged posterior fontanelle in the upper posterior angle of the parietal bone near the intersection of the sagittal and lambdoid sutures. The standard treatment for cranium bifidum occultum is observation. We present a case of a 5-year-old boy who presented with a 15x4.5 cm midline posterior cranial vault defect consistent with diagnosis of cranium bifidum occultum associated with orbital hypertelorism and a widened nose.

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A Survival Analysis with Identification of Prognostic Factors in a Series of 110 Patients with Newly Diagnosed Glioblastoma Before and After Introduction of the Stupp Regimen: A Single-Center Observational Study  Voir?

Current treatment protocol for glioblastoma multiforme (GBM) is based on maximal safe resection followed by the Stupp protocol. In Serbia, temozolomide was introduced as adjuvant therapy in 2011. The aims of this study were to confirm the safety and efficacy on overall and progression-free survival of the Stupp protocol and evaluate the influence of prognostic factors in one of the largest series of patients with GBM treated over a 2-year period.

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Membranectomy in Chronic Subdural Hematoma: Meta-Analysis  Voir?

Initial management strategies of chronic subdural hematoma (cSDH) are controversial and range from bedside twist-drill or burr-hole drainage to craniotomy with membranectomy (CWM). We aim to 1) perform a meta-analysis of the available data on the outcomes of CWM for treatment of cSDH in published English-language literature and 2) evaluate collective outcomes of CWM with respect to morbidity, mortality, and recurrence rates.

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The Corona Dentis: Description of an Anatomic Variant with Technical Implications for Anterior Odontoid Screw Placement  Voir?

Type 2 odontoid fractures are the most common cervical fractures among the elderly. Neurologic deficit is usually caused by myelopathy as a result of posterior dens migration. Direct anterior screw placement provides stabilization and can preserve C1-C2 movement. The presence of a bony excrescence on the anterior superior tip of the dens may lead to placement of a screw of incorrect length.

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Risk Factors for Preoperative Seizures and Loss of Seizure Control in Patients Undergoing Surgery for Metastatic Brain Tumors  Voir?

Metastatic brain tumors are the most common brain tumors in adults. Patients with metastatic brain tumors have poor prognoses with median survival of 6–12 months. Seizures are a major presenting symptom and cause of morbidity and mortality. In this article, risk factors for the onset of preoperative seizures and postoperative seizure control are examined.

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Characteristics of Blood Pressure Profiles After Endovascular Coiling as Predictors of Clinical Outcome in Poor-Grade Aneurysmal Subarachnoid Hemorrhage  Voir?

Accurate identification of patients who will achieve a favorable outcome is almost impossible preoperatively or postoperatively in poor-grade (Hunt and Hess Grade IV and V) aneurysmal subarachnoid hemorrhage (SAH). Whether characteristics of blood pressure profiles during the first 24 hours after endovascular coiling could predict prognosis in poor grade patients was explored.

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Assessing the Role of Preoperative Embolization in the Surgical Management of Cerebral Arteriovenous Malformations  Voir?

Preoperative embolization is established as an advantageous adjunct in multimodality treatment of cerebral arteriovenous malformations (AVMs). However, the benefit of preoperative embolization in AVMs with favorable surgical risk profile is debatable, because it has yet to be supported by evidence in comparative studies. In this study, we assessed outcome of surgically treated patients in a comparative setting.

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Meningiomas Adjacent to Major Venous Sinuses—Clinical Outcome and Recurrence  Voir?

Surgical treatment of meningiomas next to venous sinuses is difficult because of their irregular growth patterns and infiltration into the venous sinuses, making gross total resection impossible in some patients. We evaluated the postoperative clinical and neurologic course of this tumor subgroup.
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Preoperative Planning of the Lateral Entry Point Is Necessary in Percutaneous L5 Vertebroplasty  Voir?

To compare treatment outcomes and complications between the computer-assisted preoperative planning of lateral entry approach and the traditional approach for L5 percutaneous vertebroplasty.
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Endoscopic Assisted Supraorbital Keyhole Approach or Endoscopic Endonasal Approach in Cases of Tuberculum Sellae Meningioma: Which Surgical Route Should Be Favored?  Voir?

Keyhole approaches are under investigation for skull base tumor surgery. They are expected to have a low complication rate with the same successful resection rate compared with endoscopic endonasal procedures. In this study, we compare our current series of tuberculum sellae meningiomas resected via an endoscopic endonasal or microsurgical supraorbital keyhole approach.

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Fluorescein-Guided Surgery for High-Grade Glioma Resection: An Intraoperative “Contrast-Enhancer”  Voir?

Fluorescein sodium salt is widely used in medicine as fluorescein isothiocyanate and commonly named fluorescein (FL). This fluorophore has been used as a fluorescent tracer for many applications, especially in ophthalmic surgery. It was initially used in neuro-oncology in 1948 to control tumor resection margins. After a transient disuse, it has recently had a second spring with the development of dedicated filters for operating microscopes, although it is still under evaluation in clinical use. The aim of this study is to contribute to the investigation according to which FL-guided surgery for high-grade glioma (HGG) is related to better rates of gross total resection (GTR) and so to a better outcome.

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Early Diagnosis of Delayed Cerebral Ischemia: Possible Relevance for Inflammatory Biomarkers in Routine Clinical Practice?  Voir?

Delayed cerebral ischemia (DCI) after subarachnoid hemorrhage (SAH) is one of the main causes of neurologic deterioration. However, it frequently evades timely detection. Early identification and effective reversal may improve the clinical outcome. In this prospective study, we evaluate several serum inflammatory markers after aneurysmal SAH with regard to the occurrence of DCI.

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Combined Hyperactive Dysfunction Syndrome of the Cranial Nerves: A Retrospective Systematic Study of Clinical Characteristics in 44 Patients  Voir?

Combined hyperactive dysfunction syndrome (HDS) is defined as the combination symptoms arising from overactivity in cranial nerves, specifically, trigeminal neuralgia (TN), hemifacial spasm (HFS), and glossopharyngeal neuralgia (GPN), without an obvious explanatory structural lesion. This study retrospectively analyzes the clinical characteristics of combined HDS treated with microvascular decompression (MVD) in a single institution.

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Space-Occupying Tumor Bed Cysts as a Complication of Modern Treatment for High-Grade Glioma  Voir?

The management of high-grade glioma (HGG) has been affected by recent landmark trials and is now more proactive. More aggressive treatment leads to hospitalization due to side effects, however. Space-occupying tumor bed cysts have been described, but not systematically assessed. We sought to analyze this complication in a contemporary HGG cohort.

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Cystic Dilation of the Ventriculus Terminalis: Report of 6 Surgical Cases Treated with Cyst-Subarachnoid Shunting Using a T-Catheter  Voir?

Cystic dilation of the ventriculus terminalis (CDVT) is a rare anatomic variation that and may become symptomatic. Literature regarding CDVT is limited, and thus the clinical characteristics and management strategy of CDVT are unclear. Here we report 6 cases of CDVT seen in our institution, and provide a review of the current literature.

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Spinal Solitary Fibrous Tumor/Hemangiopericytoma: A Clinicopathologic and Radiologic Analysis of Eleven Cases  Voir?

To retrospectively review the clinicopathologic features and computed tomography (CT) and magnetic resonance imaging (MRI) findings of spinal solitary fibrous tumor (SFT)/hemangiopericytoma (HPC) tumors.
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Intrarectal Anesthesia in Neurosurgery  Voir?

In the early days of modern neurologic surgery, the inconveniences and potential dangers of general anesthesia by chloroform and ether using the so-called “open-drop technique” led to the quest for alternative methods of anesthesia. This became all the more necessary, since patient positioning and the surgical arrangements often hindered the use of a drop bottle. One approach to solve this problem was intrarectal ether application. The present article aims to shed light on this original, less well-known anesthesia technique in the neurosurgical field.

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Transorbital Glue Embolization of a Recurrent Venous Varix Using Real-Time Image Guidance in the Neuroangiography Suite  Voir?

Orbital lesions are challenging to access due to their location amid critical anatomic structures. Here, we demonstrate direct transorbital cannulation of an orbital venous varix using image guidance. A 36-year-old male was diagnosed with a left orbital venous varix approximately 5 years ago at an outside institution. He subsequently underwent surgery for direct intraoperative embolization of the venous varix followed by surgical resection. The patient recently presented to us with left eye pain, proptosis, double vision, and conjunctival hemorrhage precipitated by straining or lying flat.

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Metastatic Neuroendocrine Carcinoma of Unknown Origin Arising in the Femoral Nerve Sheath  Voir?

Metastatic neuroendocrine carcinoma of unknown origin is a rare condition, usually presenting with lesions in the liver and/or lung. We present the first reported case of a metastatic neuroendocrine carcinoma of unknown origin arising in the femoral nerve sheath.
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Evaluating Outcomes of Stand-Alone Anterior Lumbar Interbody Fusion: A Systematic Review  Voir?

Stand-alone anterior lumbar interbody fusion (ALIF) is an effective surgical approach for selected spinal pathologies. It avoids the morbidity and complications associated with instrumented ALIF, such as plate fixation and the traditionally used posterior approach. Despite improved disc space visualization and clearance, the associated posterior instability and increased risk of nonfusion present major challenges to this approach. The integral cage design aims to address these challenges by providing the necessary stabilization through intracorporeal screws.

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Surgical Management and Adverse Factors for Recurrence and Long-Term Survival in Patients with Hemangiopericytoma  Voir?

Intracranial hemangiopericytoma is a rare tumor with high recurrence rate. We analyzed adverse factors for recurrence and survival of patients with hemangiopericytoma.
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Prolonged Blood-Brain Barrier Disruption Following Laser Interstitial Ablation in Epilepsy: A Case Series with a Case Report of Postablation Optic Neuritis  Voir?

Laser interstitial thermal therapy has become increasingly popular for targeting epileptic foci in a minimally invasive fashion. Despite its use in >1000 patients, the long-term effects of photothermal injury on brain physiology remain poorly understood.
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Customized Polymethylmethacrylate Cranioplasty Implants Using 3-Dimensional Printed Polylactic Acid Molds: Technical Note with 2 Illustrative Cases  Voir?

Prefabricated customized cranioplasty implants are anatomically more accurate than manually shaped acrylic implants but remain costly. The authors describe a new cost-effective technique of producing customized polymethylmethacrylate (PMMA) cranioplasty implants with the use of prefabricated 3-dimensional (3D) printed molds.

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Long-Term Seizure, Quality of Life, Depression, and Verbal Memory Outcomes in a Controlled Mesial Temporal Lobe Epilepsy Surgical Series Using Portuguese-Validated Instruments  Voir?

We aimed to evaluate long-term surgical outcomes in patients treated for mesial temporal lobe epilepsy compared with a similar group of patients who underwent a preoperative evaluation.
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The Clinical Effect of Postoperative Hyperbaric Oxygen Therapy on Idiopathic Normal Pressure Hydrocephalus: A Retrospective and Comparative Analysis of 61 Patients with Ventriculoperitoneal Shunt  Voir?

The aim of the study was to examine the clinical effect of postoperative hyperbaric oxygen (HBO) therapy on symptoms and signs in the ventriculoperitoneal (VP) shunt insertion treatment of idiopathic normal pressure hydrocephalus (iNPH).
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Cost Implications of Primary Versus Revision Surgery in Adult Spinal Deformity  Voir?

Adult spinal deformity (ASD) is an important problem to consider in the elderly. Although studies have examined the complications of ASD surgery and have compared functional and radiographic results of primary surgery versus revision, no studies have compared the costs of primary procedures with revisions. We assessed the in-hospital costs of these 2 surgery types in patients with ASD.

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Dumbbell-Shaped Jugular Foramen Tumors Extending to the Neck: Surgical Considerations Based on Imaging Findings  Voir?

Dumbbell-shaped jugular foramen tumors (DSJFTs) extending to the neck present diagnostic and management difficulties because of their rarity, various pathologies, and multidisciplinary involvement. Accurate imaging findings are of great importance for surgical planning and clinical outcomes. However, few articles have discussed this issue to date.

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Unholy Alliance, Pathway to Scholarly Work, or Just an Association?  Voir?

The relationship between medical device manufacturers and surgeons has been in the spotlight in recent times. Aspersions have been cast on physicians receiving gifts, trips, and even things like pens from pharmaceutical and instrument manufacturers. Some medical school campuses have even banned representatives from such companies to set foot on their premises or to sponsor refreshments for conferences, etc. Industry-supported research has seemed to always be tainted by the presumption that results of that research must be held in question as to whether bias might have been involved with the interpretation of the results by the investigators.

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Use of Paine's Technique: Projecting Puncture Point to the Skull and Skin  Voir?

Ventriculostomy from Paine's point is an effective technique to ensure that the brain is relaxed for aneurysm surgery. This study aimed to use Paine's point for other neurosurgical procedures (except for those that require a pterional approach) by delineation of surface landmarks for identification of Paine's point on the cranium and scalp.

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Low-Cost Device for Fluorescein-Guided Surgery in Malignant Brain Tumor  Voir?

Gross total resection for malignant brain neoplasms is challenging owing to the heterogeneity of these lesions and infiltration in eloquent areas. Gross total resection is a very important part of treatment of these patients and is a crucial prognostic factor. Fluorescence-guided surgery is an important tool that improves the rate of total resection.

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Lesion Optimization for Laser Ablation: Fluid Evacuation Prior to Laser-Induced Thermal Therapy  Voir?

Magnetic resonance–guided laser-induced thermal therapy (MRgLITT) is a minimally invasive surgical procedure for ablating intracranial lesions. The presence of a fluid body can sequester thermal energy generated by the laser catheter, which compromises the performance of MRgLITT, resulting in suboptimal ablation of cystic lesions. We report our use of stereotactic fluid evacuation followed by MRgLITT in 2 patients with cystic brain tumors. This is the first report on lesion optimization by fluid aspiration before MRgLITT.

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Central Sensitization Inventory as a Predictor of Worse Quality of Life Measures and Increased Length of Stay Following Spinal Fusion  Voir?

Central sensitization is abnormal and intense enhancement of pain mechanism by the central nervous system. Patients with central sensitization may be at higher risk of poor outcomes after spinal fusion. The Central Sensitivity Inventory (CSI) was developed to identify and quantify key symptoms related to central sensitization.

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Superion Interspinous Spacer Treatment of Moderate Spinal Stenosis: 4-Year Results  Voir?

To determine 4-year clinical outcomes in patients with moderate lumbar spinal stenosis treated with minimally invasive stand-alone interspinous process decompression using the Superion device.
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Efficacy of Arachnoid-Plasty on Chronic Subdural Hematoma Following Surgical Clipping of Unruptured Intracranial Aneurysms  Voir?

We aimed to elucidate the effects of arachnoid plasty (ARP) on chronic subdural hematoma (CSDH) occurrence following clipping surgery.
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The Retrolabyrinthine Presigmoid Approach to the Anterior Cerebellopontine Region: Expanding the Limits of Trautmann Triangle  Voir?

The anatomic area exposed through exposure of Trautmann triangle may not be sufficient. We studied the additional exposure provided by skeletonizing the sigmoid sinus (SS).
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Trepanation to Treat a Head Wound: A Case of Neurosurgery from 13th-Century Tuscany  Voir?

During the archaeological excavations conducted in the 13th century cemetery of the Church of Sant'Agostino in Poggibonsi (Tuscany, Italy), a skull with evidence of neurosurgical intervention was brought to light. The skull, belonging to an adult male, shows two traumatic lesions produced by bladed instruments. The first lesion, located on the anterior part of the parietal bones, involved only the outer cranial table; bone remodeling indicates that the individual survived the injury for a long time.

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Lhermitte-Duclos Disease (Dysplastic Gangliocytoma of the Cerebellum) and Cowden Syndrome: Clinical Experience From a Single Institution with Long-Term Follow-Up  Voir?

Adult-onset Lhermitte-Duclos disease (LDD) and Cowden syndrome (CS) are considered a single phakomatosis that belongs to PTEN hamartoma tumor syndrome (PHTS) now. There is still controversy regarding the diagnosis and treatment. The authors describe the clinical features of LDD and CS with long-term follow up.

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Falcine Meningiomas: Analysis of the Impact of Radiologic Tumor Extensions and Proposal of a Modified Preoperative Radiologic Classification Scheme  Voir?

Although extensively studied, few papers have specifically addressed the surgical implications of horizontal and vertical tumor extensions in falcine meningioma (FM). The available classification systems do not address these tumor extensions and thus do not characterize FM in their entirety.
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The Prognostic Role of Tumor Volume in the Outcome of Patients with Single Brain Metastasis After Stereotactic Radiosurgery  Voir?

Patients with single brain metastasis (SBM) have better outcomes after stereotactic radiosurgery (SRS). We analyzed our SRS database to evaluate possible prognostic factors in patients with SBM.
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Postoperative Thromboembolic Prophylaxis with Low-Molecular-Weight Heparin and Risk of Rebleeding in Patients with Chronic Subdural Hematomas: A Comparative Retrospective Cohort Study  Voir?

Early postoperative administration of low-molecular-weight heparin (LMWH) to prevent thromboembolic events in patients with chronic subdural hematoma (CSDH) is controversial. Our goal was to investigate impact of early postoperative LMWH administration on recurrence rate of CSDHs.
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Complementary Relation Between Direct and Indirect Bypass in Progress of Collateral Circulation in Moyamoya Disease  Voir?

One of the important aims of surgery for moyamoya disease is to establish indirect revascularization. The purpose of this study was to assess the progress of the middle meningeal artery (MMA) after our novel preservation method and to evaluate the relation between direct and indirect bypass in the chronic stage.

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The Impact of Race on Discharge Disposition and Length of Hospitalization After Craniotomy for Brain Tumor  Voir?

Racial disparities exist in health care, frequently resulting in unfavorable outcomes for minority patients. Here, we use guided machine learning (ML) ensembles to model the impact of race on discharge disposition and length of stay (LOS) after brain tumor surgery from the Healthcare Cost and Utilization Project National Inpatient Sample.

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The Rare Association of Spina Bifida and Extrarenal Wilms Tumor: A Case Report and Review of the Literature  Voir?

The diagnosis of nephroblastoma outside of the kidneys, in the absence of a renal primary tumor, is known as extrarenal Wilms tumor (ERWT). ERWT is an uncommon entity that typically involves the embryonic path of the developing kidneys and gonads. The occurrence of ERWT in a dysraphic spine is uncommon, with no reported cases of preoperative diagnosis, with all cases diagnosed at pathology. These tumors are malignant and ideally should be completely excised. Thus, preoperative diagnosis would be highly desirable.

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The Spinal Cord Line Can Predict Postoperative Recovery for Multilevel Cervical Spondylotic Myelopathy  Voir?

To report a new index, the spinal cord (SC) line, and a new classification to predict postoperative recovery effect in patients with multilevel cervical spondylotic myelopathy (CSM).
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Gerard Blaes (Blasius) (1627–1682): The Dutch Physician and Chemist, His Work and Description of the Spinal Cord  Voir?

In this historical review we summarize the work of the Dutch physician, chemist, and anatomist Gerard Blaes (Blasius). A detailed account of his life and work is presented with emphasis on his contribution to anatomy. In particular, special reference is made to his innovative description of the spinal cord and spinal nerves. Blasius's contributions to neuroanatomy are remarkable when taking into account the limited technology of his era. As a true man of his era, he made significant contributions in research and teaching of anatomy, botany, and chemistry.

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History of Neurosurgery in Palestine  Voir?

Palestinian neurosurgery started with Dr. Antone Tarazi as the first Palestinian neurosurgeon. Before that, there was no organized neurosurgery specialty, and general surgeons performed neurosurgical procedures. Here we review the history of neurosurgery and neurosurgical applications in Palestine, evaluate some limitations of the current system, and discuss major challenges to improving this system.

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Global Diversity and Academic Success of Foreign-Trained Academic Neurosurgeons in the United States  Voir?

To quantify the proportion of academic neurosurgeons practicing in the United States who acquired residency training outside of the United States and compare their training backgrounds and academic success with those who received their residency training in the United States.
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Endoscopic Superior Ethmoidal Approach for Anterior Cranial Base Resection: Tailoring the Approach for Maximum Exposure with Preservation of Nasal Structures  Voir?

Traditional endoscopic anterior cranial base resection involves the total removal of the ethmoidal cells, including the middle and superior turbinates. This is associated with increased volume of the nasal cavity postoperatively, with increased crusting and permanent change of the nasal airflow. Here we provide a step-by-step description of the technique and evaluate the feasibility of the superior ethmoidal approach for anterior cranial base resection with maximum exposure of the anterior cranial base while keeping the middle turbinates, uncinate processes, and ostiomeatal complexes intact.

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Factors Associated with Abducens Nerve Recovery in Patients Undergoing Surgical Resection of Sixth Nerve Schwannoma: A Systematic Review and Case Illustration  Voir?

Limited or no literature exists identifying factors associated with functional nerve recovery in patients undergoing resection of sixth cranial nerve (CN VI) schwannomas.
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Assessment and Treatment of Peritumoral Cortical Veins in Parasagittal Meningiomas with Application of 3-Dimensional Imaging Fusion Model  Voir?

Operation of cortical veins is the keystone of parasagittal meningioma (PSM) resection. Little is known about pathologic changes of the veins and proper treatment. We built 3-dimensional (3D) image fusion models by neuronavigation to analyze the features of peritumoral cortical veins for PSMs and explore intraoperative treatment options.

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Intracranial Blood Flow Changes in Patients with High-Grade Severe Carotid Artery Stenosis After Stenting  Voir?

We investigated whether the cerebral hemodynamic changes of pre- and poststenting in patients with severe carotid stenosis differ by stenosis grades.
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Stereotactic radiosurgery for dural carotid cavernous sinus fistulas  Voir?

We reviewed our 7-year experience to assess the efficacy of stereotactic radiosurgery (SRS) for dural carotid cavernous fistulas (DCCFs). We analyzed the clinical outcome, complications and angiographic results.
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Assessment of the Temporopolar Artery as a Donor Artery for Intracranial-Intracranial Bypass to the Middle Cerebral Artery: Anatomic Feasibility Study  Voir?

Intracranial-intracranial bypass is a valuable cerebral revascularization option. Despite several advantages, one of the main shortcomings of the intracranial-intracranial bypass is the possibility of ischemic complications of the donor artery. However, when sacrificed, the temporopolar artery (TPA) is not associated with major neurologic deficits. We sought to define the role of TPA as a donor for revascularization of the middle cerebral artery (MCA).

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Outcome of Endoscopic Transsphenoidal Surgery for Acromegaly  Voir?

Endoscopic transsphenoidal surgery has recently been introduced in pituitary surgery. We investigated outcomes and complications of endoscopic surgery in 2 referral centers in Korea.
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Increased Transfusion of Fresh Frozen Plasma is Associated with Mortality or Worse Functional Outcomes After Severe Traumatic Brain Injury: A Retrospective Study  Voir?

The fresh frozen plasma (FFP) transfusion threshold and timing for traumatic brain injury (TBI)-associated coagulopathy are controversial. Thus, a multicenter retrospective study was conducted to determine whether or not FFP transfusion is associated with poor outcomes after severe TBI.
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Quality Indicators in Cranial Neurosurgery: Which Are Presently Substantiated? A Systematic Review  Voir?

Owing to the rising costs of health care delivery, the quality of delivered care has become a central issue across all medical specialties. Consequently, there is increasing pressure to create standardized frameworks for measuring quality of care. In the field of cranial neurosurgery, health care administrators have begun applying quality measures that are easily available but might be inaccurate in measuring the quality of care.

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Professional Autonomy  Voir?

In 1972, I completed my first year of medical studies and that August, a lifelong idol passed away, very unexpectedly. He also attended the oldest medical school west of the Mississippi, although in his era there wasn't a specialty called neurological surgery. For as long as I remember as a baby-boomer growing up in the 1960s, this silver-haired, family doc kept a tiny, 3-room upstairs office, accessible only by a steep and odorous flight of stairs. His mode of practice was simple—take care of “one patient at a time.” It was professional attention at its best, with emphasis on ample patient time to chat about family and life.

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Vaginal Migration of Ventriculoperitoneal Shunt Catheter and Cerebrospinal Fluid Leak as a Complication of Hysterectomy  Voir?

Ventriculoperitoneal (VP) shunting is a common neurosurgical procedure to treat hydrocephalus that diverts cerebrospinal fluid from the cerebral ventricles to the peritoneal cavity for reabsorption. The distal catheter may potentially migrate through any potential or iatrogenic opening in the peritoneal cavity. Increasingly successfully management of childhood hydrocephalus and adult-onset conditions leading to hydrocephalus, such as subarachnoid hemorrhage, is leading many adult female patients harboring VP shunts needing to undergo hysterectomy.

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Isolated Transverse Process Fractures and Markers of Associated Injuries: The Experience at University of California, Los Angeles  Voir?

To report a single-institution experience with isolated transverse process fractures (ITPFs) and provide increasing support for the development of evidence-based guidelines. The authors also evaluated the presence of concerning symptoms or red flags that may indicate additional, underlying injuries in the setting of ITPFs.

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The Protective Effect of Omeprazole Against Traumatic Brain Injury: An Experimental Study  Voir?

The development of secondary brain injury via oxidative stress after traumatic brain injury (TBI) is a well-known entity. Consequently, the aim of the present study was to evaluate the role of omeprazole (OM) on rat model of TBI.
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Brain Arteriovenous Malformations Supplied by the Anterior Choroidal Artery: Treatment Outcomes and Risk Factors for Worsened Muscle Strength After Surgical Resection  Voir?

The treatment of brain arteriovenous malformations (BAVMs) supplied by the anterior choroidal artery (AChA), or aBAVMs, remains challenging. The aim of this study was to determine the surgical outcomes and risk factors for worsened muscle strength (MS) after surgery in patients with aBAVMs.
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Drain Insertion in Chronic Subdural Hematoma: An International Survey of Practice  Voir?

To investigate whether, after the publication of grade I evidence that it reduces recurrence rates, the practice of drain insertion after burr-hole drainage of chronic subdural hematoma has changed. Further, we aimed to document various practice modalities concerning the insertion of a drain adopted by neurosurgeons internationally.

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Posttraumatic Seizures in a Rural Nigerian Neurosurgical Service  Voir?

Traumatic brain injury (TBI) is a recognized risk factor for seizures. In Nigeria, there is paucity of literature on posttraumatic seizure (PTS). This study provides the profile and pattern of PTS in patients with TBI in a rural Nigerian neurosurgical service.
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Does Stereotactic Radiosurgery Positively Impact the Local Control of Atypical Teratoid Rhabdoid Tumors?  Voir?

Atypical teratoid rhabdoid tumors (ATRTs) are rare and aggressive tumors, usually affecting patients younger than 3 years of age, that are characterized by a poor prognosis. Nowadays multimodal management, including surgery, chemotherapy and radiation therapy (RT), is advocated depending on the patients' age and tumor stage, even if no consensus exists regarding the best treatment modality. Local RT seems to be the most effective treatment in prolonging progression-free and overall survival rates, although RT might not be used on younger children because of the risk of neurocognitive and endocrine sequelae.

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Complete Removal of the Epitrochleoanconeus Muscles in Patients with Cubital Tunnel Syndrome: Results From a Small Prospective Case Series  Voir?

Sometimes during surgery for cubital syndrome an anomalous muscle called the epitrochleoanconeus is encountered. Different surgical strategies on how to decompress the ulnar nerve in the presence of this muscle have been proposed, including transection of the muscle, resection, or subcutaneous transposition of the ulnar nerve. Because of the low incidence, there is no consensus on what type of surgical treatment can best be performed. In the present study, we prospectively followed a small series of patients, in which the muscle was resected.

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Does One Size Fit All? Examining the Application of Neurosurgery Residency Milestones Developed in the United States to a Taiwanese Culture  Voir?

The Milestone Project was launched in 2009, charging specialties to develop specific educational accomplishments required to establish clinical competency. The milestone assessment method was first introduced to Taiwan in 2013 and before applying milestone assessments to our medical education system, the validity and reliability of these questionnaires needed to be evaluated.

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Metabolic In Vivo Visualization of Pituitary Adenomas: a Systematic Review of Imaging Modalities  Voir?

Pituitary adenomas (PAs) are the most common intrasellar mass. Functional PAs constitute most of pituitary tumors and can produce symptoms related to hormonal overproduction. Timely and accurate detection is therefore of vital importance to prevent potentially irreversible sequelae. Magnetic resonance imaging is the gold standard for detecting PAs, but is limited by poor sensitivity for microadenomas and an inability to differentiate scar tissue from tumor residual or predict treatment response.

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Adapting to the Rapid Evolution of Healthcare from a Shared Perspective  Voir?

In a recent issue of WORLD NEUROSURGERY, Castlen et al. offer comprehensive insights into the conflicts between physicians and administrators in the changing healthcare landscape, recognizing causes for tension stemming from their distinctly different viewpoints when adapting to industrialization of healthcare as a business and to increasing complexities in healthcare practice and management resulting from technological advancement. Particularly cogent are the authors' precisely detailed perspectives of both physicians and administrators.

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Role of Conventional Myelography in Diagnosis and Treatment of Degenerative Spine Disease in Low-Income Communities: Prospective Study  Voir?

Chronic back pain is a common problem, and imaging is crucial for effective diagnosis and treatment. In low-resource settings conventional myelography is a cheap alternative to magnetic resonance imaging and computed tomography. This study was conducted to reexamine the diagnostic reliability, effectiveness for surgical decision making, and safety of conventional myelography.

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Delayed Venous Drainage in Ruptured Arteriovenous Malformations Based on Quantitative Color-Coded Digital Subtraction Angiography  Voir?

Clinically applicable hemodynamic risk factors to predict arteriovenous malformation (AVM) rupture are missing in the literature. The aim of this study was to use catheter angiography to identify hemodynamic parameters in ruptured and unruptured AVMs.
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Prognostic Factors and Survival Outcome in Patients with Chordoma in the United States: A Population-Based Analysis  Voir?

To evaluate prognostic factors of patients with chordoma through a population-based analysis.
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Factors Affecting the Obliteration Rate of Intracranial Aneurysms Treated with a Single Pipeline Embolization Device  Voir?

To evaluate the clinical and angiographic outcomes of intracranial aneurysm treatment using a single Pipeline embolization device (PED), and to evaluate the factors affecting aneurysm obliteration rate.
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Surgeon Adherence to Medical Ethics as Contingent on Their Leadership in the Changing Economics of Health Care  Voir?

In a paper recently published in WORLD NEUROSURGERY, Castlen et al.1 examined the emerging tensions between hospital administrators and physicians in increasingly complicated health care systems. With costs, quality, and accessibility increasingly being scrutinized, health care has understandably been subjected to increased regulation. Consequently, Castlen et al.1 highlighted how unbiased medical care achieved by physician autonomy—a principle tenet of medical ethics and professionalism—is at risk by resource-minded administrative control.

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Quantitative Computed Tomography Ventriculography for Assessment and Monitoring of Hydrocephalus: A Pilot Study and Description of Method in Subarachnoid Hemorrhage  Voir?

There is no facile quantitative method for monitoring hydrocephalus (HCP). We propose quantitative computed tomography (CT) ventriculography (qCTV) as a novel computer vision tool for empirically assessing HCP in patients with subarachnoid hemorrhage (SAH).
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Aneurysms of the Proximal Segment of the Anterior Cerebral Artery: A New Classification System with Corresponding Therapeutic Options  Voir?

This study aims to establish a new classification system for proximal anterior cerebral artery (A1) aneurysms and to offer treatment strategies, based on the lessons learned by studying the case reports of 41 patients with A1 aneurysms.
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A New Determinant of Poor Outcome After Spontaneous Subarachnoid Hemorrhage: Blood pH and the Disruption of Glossopharyngeal Nerve–Carotid Body Network: First Experimental Study  Voir?

The chemoreceptor network, consisting of the glossopharyngeal nerve and carotid body (GPN-CB), is essential for the regulation of blood pH. Its ischemic insults after subarachnoid hemorrhage (SAH), which may contribute to acidosis, have not been investigated.
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E-WIN Project 2016: Evaluating the Current Gender Situation in Neurosurgery Across Europe—An Interactive, Multiple-Level Survey  Voir?

The proportion of women among neurosurgeons appears to be growing worldwide with time. Official data concerning the current situation across Europe have not yet been published. Thus, there are still concerns about gender inequality. The European Women in Neurosurgery Project 2016 was designed to recognize the current situation across Europe.

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Accuracy of VarioGuide Frameless Stereotactic System Against Frame-Based Stereotaxy: Prospective, Randomized, Single-Center Study  Voir?

Frameless stereotactic brain biopsy systems are widely used today. VarioGuide (VG) is a relatively novel frameless system. Its accuracy was studied in a laboratory setting but has not yet been studied in the clinical setting. The purpose of this study was to determine its accuracy and diagnostic yield and to compare this with frame-based (FB) stereotaxy.

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Repeat Stereotactic Radiosurgery for Locally Recurrent Brain Metastases  Voir?

The outcomes of repeat stereotactic radiosurgery (SRS) after failure of previous SRS are not well established. We report our overall experience using SRS for the retreatment of locally recurrent brain metastases.
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Assessing the Relevancy of “Citation Classics” in Neurosurgery. Part II: Foundational Papers in Neurosurgery  Voir?

The second part of this study reanalyzes Ponce and Lozano's (2010) list of classics to create a new list of “foundational” articles in neurosurgery. Ponce and Lozano (2010) previously published a list of 106 neurosurgery classics, as defined by Garfield and his 400 citation criterion.
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Assessing the Relevancy of Highly Cited Works in Neurosurgery. Part I: The 100 Most Relevant Papers in Neurosurgical Journals  Voir?

Bibliometric analyses based on total citation count come with many limitations, which investigators in other fields have overcome using the average number of citations per year since publication.
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Is There a Formula for Residency Selection of Future Academic Neurosurgeons?  Voir?

In this enlightening article, Chaichana et al.1 set out to evaluate the impact of published research before and during residency in eventually attaining neurosurgery faculty positions in academic hospitals. To arrive at their findings, the authors collected alumni information from 65 neurosurgery residency websites (60% of programs), and analyzed 949 graduates from programs between 2005 and 2015 for factors associated with an academic career, including information on publications, citations, and H-index (i.e., the productivity and impact of the citation).

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The Development of Better Neurosurgical Care Around the World  Voir?

Health care issues continue to be worrying worldwide, especially in developing countries. This subject becomes more complex in highly complicated specialties such as neurosurgery, a medical specialty that is considered extremely expensive and dependent on high technology for its practice. Therefore, countries with fewer financial resources typically have less access to adequate neurosurgical care.1 In an article recently published in WORLD NEUROSURGERY, Haranhalli et al.2 present extremely beneficial results demonstrating improvement in all aspects of neurosurgical care.

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Chiari Malformation Type 1: A Systematic Review of Natural History and Conservative Management  Voir?

Chiari malformation type 1 (CM-1) is a variation of hindbrain development that can sometimes occur in asymptomatic individuals. Conventional treatment is surgical decompression, but little is known about the natural history of patients who do not undergo surgical management. This information is critical to determine how these patients should be managed. We conducted a systematic literature review to determine the natural history of CM-1, particularly in patients who did not undergo surgery and in asymptomatic individuals, to help patients and physicians determine when surgery is likely to be beneficial.

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Use of Intracranial Pressure Monitoring Frequently Refutes Diagnosis of Idiopathic Intracranial Hypertension  Voir?

The diagnosis and management of patients with idiopathic intracranial hypertension (IIH) frequently relies on lumbar puncture to ascertain intracranial pressure (ICP). However, ICP values derived this way may be spurious owing to patient body habitus and behavior. We recently incorporated direct continuous ICP monitoring into the work-up for IIH.

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Therapeutic Options for Recurrent High-Grade Gliomas: A Perspective Statement  Voir?

High-grade gliomas (HGGs), comprising World Health Organization (WHO) grade III and IV tumors, are associated with dismal prognosis regarding progression-free survival (PFS) and overall survival (OS). According to current data, the expected median OS for patients with newly diagnosed anaplastic astrocytomas (WHO III) and glioblastoma multiforme (GBM; WHO IV) still remains in the range of only 24–36 and 12–15 months, respectively.1,2 All patients suffering from HGGs will eventually develop tumor recurrences and succumb to their disease.

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Superficial Temporal Artery–Middle Cerebral Artery Bypass Surgery for Refractory Symptomatic Intracranial Atherosclerotic Stenosis  Voir?

To evaluate blood flow changes after bypass surgery for refractory symptomatic intracranial atherosclerotic stenosis (ICAS).
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Analysis of 137 Patients Who Underwent Endoscopic Transsphenoidal Pituitary Adenoma Resection Under High-Field Intraoperative Magnetic Resonance Imaging Navigation  Voir?

Pure endoscopic resection has become the most popular surgical approach for pituitary adenoma. Intraoperative magnetic resonance imaging (iMRI) systems have been in use for endoscopic resection of pituitary adenomas. This study aimed to evaluate the effectiveness of iMRI and neuroimaging navigation techniques during endoscopic endonasal transsphenoidal surgery of pituitary adenomas.

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Outcome of Biomedical Glue Sling Technique in Microvascular Decompression for Hemifacial Spasm Involving the Vertebral Artery  Voir?

Microvascular decompression (MVD) is the most useful treatment for hemifacial spasm (HFS). In cases of vertebral artery (VA) compression of the facial nerve, MVD is often difficult. In this study, we compared the outcome of the biomedical glue sling technique with the traditional technique in MVD for HFS involving the VA.

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Microsurgical Resection After Failed Gamma Knife Radiosurgery of Papillary Tumor of the Pineal Gland  Voir?

Primary papillary tumors of the pineal region are rare entities with distinct histopathologic characteristics. The most common surgical approaches include the supracerebellar infratentorial corridor or the occipital interhemispheric approach. Gamma knife radiosurgery (GKRS) is an acceptable treatment modality for parenchymal tumors of the pineal gland and often is used as a primary treatment modality for asymptomatic and indolent lesions and as an adjunct to surgical resection. In this presentation, we describe the surgical nuances of posterior interhemispheric approach in an elderly man with a previously failed empirical GKRS.

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Effect of Baseline Characteristics on the Outcome of Stent Retriever–Based Thrombectomy in Acute Basilar Artery Occlusions: A Single-Center Experience and Pooled Data Analysis  Voir?

To explore the association of baseline characteristics and the outcome of patients with acute basilar artery occlusion (BAO) after stent retriever–based thrombectomy (SRT).
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Endovascular Treatment of Complex Distal Posterior Cerebral Artery Aneurysms with the Pipeline Embolization Device  Voir?

The purpose of our study is to assess the safety and efficacy of the Pipeline Embolization Device (PED) for endovascular treatment of complex, distal posterior cerebral artery (PCA) aneurysms.
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Single-Session Hematoma Removal and Transcranial Coil Embolization for a Cavernous Sinus Dural Arteriovenous Fistula: A Technical Case Report  Voir?

Patients with cavernous sinus dural arteriovenous fistulas (CS dAVFs) with cortical venous varix are indicated for aggressive treatment because of the associated risk for intracranial hemorrhage.
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Primary Spinal Cord Glioblastoma Multiforme: A Retrospective Study of Patients at a Single Institution  Voir?

[Background and objective] Primary spinal cord (PSC) glioblastoma multiforme GBM is extremely rare, which accounts for only 1.5% of all SC tumors. Therefore, its treatment is still ill defined. To elucidate prognostic factors, we performed a single-institutional retrospective review on the largest series to date of the patients with PSCGBM who underwent surgical resection in West China Hospital during the period between 2008 and 2014. A total of 14 PSCGBM patients were collected.[Method] Demographic, operative, and post-operative factors were recorded.

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Hybrid Bone Single Photon Emission Computed Tomography Imaging in Evaluation of Chronic Low Back Pain: Correlation with Modic Changes and Degenerative Disc Disease  Voir?

Multiple radiologic modalities are used in the evaluation of patients with low back pain (LBP). Only limited evidence currently exists to support the use of bone hydroxydiphosphonate single photon emission computed tomography (SPECT/CT) in patients with Modic changes (MCs) and degenerative disc disease. The aim of this study was to assess the value of the hybrid bone SPECT/CT imaging in patients with chronic LBP. We evaluate the correlation of hybrid bone SPECT/CT imaging patterns with MCs and disc abnormalities on magnetic resonance imaging (MRI).

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Risk Factors to Predict Neurologic Complications After Endovascular Treatment of Unruptured Paraclinoid Aneurysms  Voir?

Unruptured paraclinoid aneurysms are often asymptomatic, and endovascular coiling is the main treatment. However, endovascular treatment of these lesions still leads to neurologic complications. We aimed to identify predictors of neurologic complications in these lesions.
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Overlapped Stenting Combined with Coiling for Blood Blister-Like Aneurysms: Comparison of Low-Profile Visualized Intraluminal Support (LVIS) Stent and Non-LVIS Stent  Voir?

To evaluate the safety and efficacy of overlapped stenting for blood blister-like aneurysms (BBAs) and to compare the outcomes between Low-profile Visualized Intraluminal Support (LVIS) and non-LVIS stents.
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Transforming Growth Factor Beta Family in the Pathogenesis of Meningiomas  Voir?

Meningiomas account for 36% of primary brain tumors. The pathogenesis of these tumors is not completely established, hindering development of effective chemotherapy. Numerous studies have identified alterations in several growth factors and receptor kinases that regulate meningioma growth. These may be targets for new therapies. One of these, sometimes overlooked, is the transforming growth factor beta (TGF-β) family of proteins. Its receptors and signaling pathways play a critical role in development or progression of many forms of neoplasia.

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Which is the more appropriate proximal fusion level for adult lumbar degenerative flat back?  Voir?

To determine the optimal proximal fusion level after long instrumented fusion to the sacrum for lumbar degenerative flat back.
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Micro-Multileaf Collimator LINAC Radiosurgery for Vestibular Schwannomas  Voir?

This study evaluates the efficacy of linear accelerator (LINAC) radiosurgery using micro multi-leaf collimator technique (μMLC) in the treatment of a consecutive series of patients with vestibular schwannomas.
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Bone Morphogenetic Proteins in Anterior Cervical Fusion: A Systematic Review and Meta-Analysis  Voir?

Bone morphogenetic proteins (BMPs) have been commonly used as a graft substitute in spinal fusion. Although the U.S. Food and Drug Administration issued a warning on life-threatening complications of recombinant human BMPs (rhBMPs) in cervical spine fusion in 2008, their off-label use has been continued. This investigation aimed to review the evidence for the use of rhBMP-2 and rhBMP-7 in anterior cervical spine fusions.

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Delayed Carotid Pseudoaneurysms from Iatrogenic Clival Meningeal Branches Avulsion: Recognition and Proposed Management  Voir?

Carotid injury during anterior skull base approaches is promptly recognizable and mandates immediate treatment; likewise, development of pseudoaneurysms after such injuries is anticipated and managed.
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Joseph Buford Pennybacker, C.B.E., M.D., F.R.C.S. (1907–1983): Continuing Sir Hugh Cairns' Oxford Legacy and Pioneer of the Modern Management of Cerebral Abscesses  Voir?

The authors examine the life and contribution of Joseph Buford Pennybacker to British neurosurgery and the modern management of cerebral abscesses.Pennybacker's inspirational journey began with him aspiring to follow in the footsteps of the pioneering surgeon, Ephraim McDowell. It saw him cross the Atlantic, learn medicine at Edinburgh, train in neurology at Queen Square in London, and study neurosurgery under Sir Hugh Cairns in Oxford. Pennybacker navigated a successful career through World War II and together with Cairns established the Radcliffe Infirmary in Oxford as a highly esteemed neurosurgical unit.

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Comparing Quality of Life in Cervical Spondylotic Myelopathy with Other Chronic Debilitating Diseases Using the SF-36 Survey  Voir?

Although cervical spondylotic myelopathy (CSM) can be devastating, its relative impact on general health remains unclear. Patient responses to the SF-36 PCS/MCS were compared between CSM and other diseases to evaluate their respective impacts on quality of life.
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Pilocytic Astrocytoma of fornix mimicking a colloid cyst: report of two cases and review of the literature  Voir?

Colloid cyst is a gelatin-containing cyst in the brain almost always found in the third ventricle. The specific shape and location of these cysts, a round well-delineated mass in the rostral part of the third ventricle adjacent to the foramen of Monro, on imaging are the main findings for diagnosis. Several masses of the third ventricle masquerading colloid cysts on images have been reported yet. Based on different surgical approach, pre-operative misdiagnosis of colloid cyst may have great impact on prognosis.

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Chronic Spinal Subdural Hematoma Associated with Antiplatelet Therapy  Voir?

Spinal subdural hematoma is a rare clinical entity marked by the onset of pain and paralysis, which is usually associated with hemorrhagic disorders, trauma, and iatrogenic causes such as lumbar puncture or epidural anesthesia.
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WITHDRAWN: The modified impact factor; a letter to the editor  Voir?

This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause.The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy.
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WITHDRAWN: Outcomes After Anterior Lumbar Interbody Fusion Versus Transforaminal Lumbar Interbody Fusion for the Treatment of Symptomatic L5–S1 Spondylolisthesis: A Prospective, Multi-Institutional Comparative Effectiveness Study  Voir?

Available online 25 September 2015
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WITHDRAWN: Refining the Role for Evacuation of Spontaneous Intracerebral Hematomas: Results of STICH II  Voir?

The Publisher regrets that this article is an accidental duplication of an article that has already been published, DOI of original article: http://dx.doi.org/10.1016/j.wneu.2014.08.046. The duplicate article has therefore been withdrawn.The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy.

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Upcoming Events  Voir?

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Editor's Choices  Voir?

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Subscription Information  Voir?

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Editorial Board  Voir?

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Contents  Voir?

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The Fringes  Voir?

We, at WORLD NEUROSURGERY, have introduced a variety of innovations in information transmission. They have ranged from the aesthetics (e.g., filler and cover art) to new sections that emphasize our global and humanitarian mission (e.g., the “Doing More with Less” section). This, my 29th Editor-in-Chief letter, focuses on our global and humanitarian mission. In the prior issue, my July 2017 Editor-in-Chief letter discussed our mission statement and the dynamic nature of truly meaningful mission statements.

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In Reply to the Letter to the Editor Regarding “Acute Spinal Epidural Hematoma After Acupuncture: Case Report and Literature Review”  Voir?

In response to the remarks from Gan et al.1 concerning our article, “Acute Spinal Epidural Hematoma After Acupuncture: Case Report and Literature Review,”2 we would like to highlight the following important points. Regarding the precise acupuncture technique performed in the case reported in the article, we decided to report exactly what explained by the acupuncturist concerning both the entry points and the needles employed. A higher level of accuracy could not be reached because 4 months had passed from the time of the acupuncture treatment to our interview with the acupuncturist, and no detailed report about this treatment was ever compiled.

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In Reply To “Moyamoya Disease: From Hypoperfusion to Network Disruption”  Voir?

We thank Dr. Lanterna for his thoughtful and constructive comments on our article, which elucidated the theory of moyamoya disease (MMD) networks: from hypoperfusion to network disruption. In our report, we retrospectively reviewed 82 patients (164 hemispheres) with MMD at late Suzuki stage from a single institution in China.1 We concluded that although direct bypass surgery was shown to effectively improve the cerebral perfusion in patients with MMD at late Suzuki stage, compared with conservative treatment, it did not reduce the risk of recurrent stroke.

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In Reply to the Letter to the Editor Regarding “Six Walls of the Cavernous Sinus Identified by Sectioned Images and Three-Dimensional Models: Anatomic Report”  Voir?

We have read the letter by Taghipour and Ghaffarpasand addressing our article.1 Whereas our article described the cavernous sinus (CS) from the perspective of anatomic images, Taghipour and Ghaffarpasand do so from the perspective of embryology. We are glad that the discussion in the letter enriched our research on the CS.

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In Reply to “Risk Factors for Poor Outcome in Hypertensive Intraventricular Hemorrhage Treated by External Ventricular Drainage with Intraventricular Fibrinolysis: Statistical and Methodologic Issues”  Voir?

First of all, I thank Drs. Ayubi and Safiri for their kind suggestions. I read their suggestions about statistical and methodological issues in our paper very carefully, and reanalyzed our data in both the univariate and multivariate models. I admit that there were some mistakes in our Tables 2 and 3,1 because some sample data were lost when using SPSS software, owing to our busy clinical work. I apologize for our carelessness and possible adverse impact on the readers of the Journal. Fortunately, these missing data do not affect our interpretation of the results.

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In Reply to “Is Internal Maxillary Artery Bypass Feasible without Zygomatic Osteotomy?”  Voir?

We appreciate the interest of Wang and colleagues in our article. We thank the editor for giving us this opportunity to respond to the valuable insights offered in their commentary.
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Moyamoya Disease: From Hypoperfusion to Network Disruption  Voir?

I read with great interest the article by Ge et al.1 examining the effectiveness of the superficial temporal artery to the middle cerebral artery (STA-MCA) bypass in patients with moyamoya disease (MMD) at late Suzuki stage. The authors retrospectively reviewed a series of 82 patients with an average follow-up of 55.1 ± 16.2 months. During the follow-up, a stroke event was experienced in 9% of the conservatively treated hemispheres, and in 10% of surgically treated hemispheres. The authors concluded that although the bypass may improve cerebral perfusion, it does not offer significant advantages in terms of stroke prevention in patients in late Suzuki stage.

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Letter to the Editor Regarding “Acute Spinal Epidural Hematoma After Acupuncture: Case Report and Literature Review”  Voir?

We read the article by Domenicucci et al., entitled “Acute Spinal Epidural Hematoma after Acupuncture: Personal Case and Literature Review,”1 which triggers an alarm for clinical acupuncture manipulation, with great interest. However, we still have some questions for this case.
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Physicians, Ethics, and Hospital Management  Voir?

For human beings, immortality is a latent dream. This aspiration is thwarted, however, by illness and particularly by the limited financial resources available in a unique place—the hospital—where care providers and nonmedical personnel struggle to overcome these limitations and restore life. Therein lies the paradox: a hospital is not an ordinary business undertaking; it is too much a part of the crux of life—as when, for instance, we come into the world or leave it. In their article recently published in WORLD NEUROSURGERY, Castlen et al.

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Risk Factors for Poor Outcome in Hypertensive Intraventricular Hemorrhage Treated by External Ventricular Drainage with Intraventricular Fibrinolysis: Statistical and Methodologic Issues  Voir?

We were interested to read the paper authored by Fu et al.1 that was published in WORLD NEUROSURGERY in March 2017. The authors aimed to evaluate the association between preoperative factors and outcome in patients with hypertensive intraventricular hemorrhage (HIVH) treated by external ventricular drainage (EVD) plus intraventricular fibrinolysis. They found that age, Glasgow Coma Scale score, blood neuron-specific enolase, third-ventricle hematoma, and fourth-ventricle hematoma were associated independently with poor outcomes of EVD in patients with HIVH.

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Statin Use in Patients with Aneurysmal Subarachnoid Hemorrhage May not Significantly Reduce the Occurrence of Delayed Ischemic Neurological Deficit  Voir?

With great interest, we read the article by Akhigbe et al1 entitled “Cholesterol-reducing agents for treatment of aneurysmal subarachnoid haemorrhage: systematic review and meta-analyses of randomized controlled trials” published in the February 2017 issue of WORLD NEUROSURGERY. They performed a meta-analysis of randomized controlled trials to evaluate the efficacy of statin use in patients with aneurysmal subarachnoid hemorrhage (aSAH). The study is of profound academic importance, and there are some points we would like to address.

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Syringostomy Using Myringostomy Tube  Voir?

I enjoyed reading the article by Tassigny et al.1 entitled “Shunting of Syringomyelic Cavities by Using a Myringotomy Tube: Technical Note and Long-Term Results,” published in the February 2017 issue of WORLD NEUROSURGERY. In the abstract section, the authors had noted that “the purpose of the (present) study was to describe a simple and efficient surgical technique and to report the long-term radioclinical outcomes.” Reading this and their introductory sentence, “Our purpose in the present study was to describe our surgical technique, to report the long-term radioclinical outcomes, compare with other procedures described in the literature…,” any reader will spontaneously think that they are reading a very original idea.

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Neuroendoscope: Evolving Spectrum of Utility in the Management of Hydrocephalus, Biopsy, and Resection of Ventricular Tumors and Cyst Fenestration  Voir?

The article by Giannetti et al1 titled “Does the Simultaneous Use of a Neuroendoscope Influence the Incidence of Ventriculoperitoneal Shunt Infection?” published in your esteemed journal was read with great interest. The authors shared their experience working at the Clinical Hospital of the Federal University of Minas Gerais in Belo Horizonte, Brazil to investigate the probability of a rise in risk while using an endoscope in association with ventriculoperitoneal (VP) shunt surgery compared with patients who underwent only VP shunt surgery.

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Letter to the Editor Regarding “Impact of Intraoperative Monitoring During Elective Complex Spinal Fusions (≥4 Levels) on 30-Day Complication and Readmission Rates: A Single Institutional Study of 643 Adult Spinal Deformity Patients”  Voir?

In the article “Impact of Intraoperative Monitoring During Elective Complex Spinal Fusions (≥4 Levels) on 30-Day Complication and Readmission Rates: A Single Institutional Study of 643 Adult Spinal Deformity Patients,”1 the authors present results that point toward a lack of difference between cases with intraoperative monitoring (IOM) and those without IOM in 30-day admission rates. We find the presentation of the data in this article to be potentially misleading.

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Letter to the Editor Regarding “Six Walls of the Cavernous Sinus Identified by Sectioned Images and Three-Dimensional Models: Anatomic Report”  Voir?

We read with interest the article by Chung et al1 entitled “Six Walls of the Cavernous Sinus Identified by Sectioned Images and Three-Dimensional Models: Anatomic Report” published in WORLD NEUROSURGERY. They conducted a cadaveric study in order to determine the precise anatomy of the cavernous sinus (CS). On the basis of the results, they proposed a hexahedron theory by which the anatomy was discussed. We would like to add some important points to this valuable study.

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Evolution of Different Surgical Treatment Techniques for Management and Improving Outcome of Chiari Malformation Type 1  Voir?

The article by Yilmaz et al.,1 entitled “Adding Expansile Duraplasty to Posterior Fossa Decompression May Restore Cervical Range of Motion in Grade 3 Chiari Malformation Type 1 Patients,” published recently in WORLD NEUROSURGERY, was read with great interest. The authors investigated the effect of posterior fossa surgical decompression with expansile duraplasty on postoperative occipitocervical mobility, cervical lordosis, and cervical spine stability in 76 cases of symptomatic Chiari malformation type 1 by evaluating cervical range of motion and cervical lordosis.

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Expanding Horizon of Neuroendoscopic Procedure from Endoscopic-Assisted Tumor Resection, Vascular Surgery, and Management of Hydrocephalus to Diagnostic and Therapeutic Management of Pyogenic Ventriculitis  Voir?

I read with great interest the article by Wang et al1 “Management of Pyogenic Cerebral Ventriculitis by Neuroendoscopic Surgery” published recently in WORLD NEUROSURGERY. Pyogenic cerebral ventriculitis is often associated with an unfavorable outcome, and the cost of therapy is high. Various management options including external ventricular drain, removal of infected and malfunctioning VP shunt, antimicrobial therapy, and endoscopic surgery are reported in the literature. Ventriculitis associated presence of intraventricular debris, bacterial plaques, formation of multiple septation, and multiloculated hydrocephalus development and can also be treated with endoscopic septostomy, removal of intraventricular debris, intraventricular antibiotic solution irrigation, with simultaneous external ventricular drain placement.

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In Reply to “Craniopharyngioma: Surgical Outcome as Related to the Degree of Hypothalamic Involvement”  Voir?

We greatly appreciate the thoughtful and scholarly letter from Dr. Prieto and colleagues in response to our article describing the surgical results of endoscopic endonasal skull (EES) base surgery for craniopharyngioma, performed to preserve hypothalamic function.1 We admire the series of work by Dr. Prieto et al2-4 in which a classification system for craniopharyngioma, based on tumor topography, was used and visual outcome, surgical risk of hypothalamic damage, and recurrence rate were predicted.

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Expanding Spectrum and Diversifying Role of Laser Beam from Intraoperative Cranial Surgery Adjunct to Magnetic Resonance–Guided Minimally Invasive Thermal Laser Ablation Therapy for Intracranial Tumor  Voir?

The article by Ivan et al.,1 entitled “Magnetic Resonance–Guided Laser Ablation for the Treatment of Recurrent Dural-Based Lesions: A Series of Five Cases,” published recently in WORLD NEUROSURGERY, was read with great interest. The authors reported their experience of magnetic resonance–guided laser-induced thermotherapy (MR-LITT) of radiologically progressive, recurrent dural-based intracranial lesions, which were located in the hemispheric convexity or paramedian regions of the supratentorial compartment and included 4 meningiomas and 1 solitary fibrous tumor.

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Primary Spinal Cord Glioblastoma Multiforme: A Rare but Uniformly Fatal Neoplasm  Voir?

The article by Behmanesh et al.,1 entitled “Management of Patients with Primary Intramedullary Spinal Cord Glioblastoma,” published in WORLD NEUROSURGERY, was read with great interest. The authors present 4 cases of spinal cord glioblastoma multiforme (GBM) managed at their institution over a 10-year period. All patients were female, and the mean age was 33.5 years (range, 14–50 years). Two tumors each were located in the cervical and thoracic region. Preoperatively, there was 1 patient each with McCormick grade I–IV.

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Craniopharyngioma: Surgical Outcome as Related to the Degree of Hypothalamic Involvement  Voir?

We have read with great interest the article entitled “Surgical outcomes of endoscopic endonasal skull base surgery of craniopharyngiomas evaluated according to the degree of hypothalamic extension” that Yano et al. recently published in WORLD NEUROSURGERY.1 These authors have retrospectively analyzed the relationship between the degree of extension of the craniopharyngiomas (CPs) into the hypothalamus and the surgical outcome in a series of 18 patients, including 11 primary and 7 recurrent tumors, who underwent 20 endoscopic endonasal surgical procedures (EES).

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Is Internal Maxillary Artery Bypass Feasible without Zygomatic Osteotomy?  Voir?

We read with great interest the article by Yagmurlu et al.1 recently published in WORLD NEUROSURGERY regarding new landmarks for localizing the internal maxillary artery (IMA) in the infratemporal fossa when performing IMA-to-middle cerebral artery high-flow bypass. In their article, the authors proposed that the IMA can be reached by following the deep temporal artery or the sphenoid groove/pterygomaxillary fissure. In addition, the authors illustrated an easier method to perform proximal anastomosis between the IMA and a graft conduit without zygomatic osteotomy or resection of the middle fossa floor.

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Dernière mise à jour : 27/07/2017 : 04:31


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