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Sommaires des Revues - Word Neurosurgery

World Neurosurgery

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Surgical Outcome of Very Small Intracranial Aneurysms Utilizing the Double Clip Technique  Voir?

To report the outcome of patients with VSIA undergoing surgical clipping utilizing a double clip technique.
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Surgical resection of anterior and posterior butterfly glioblastoma  Voir?

Evidence suggests a survival benefit for patients with glioblastoma who undergo maximal safe surgical resection. Not all glioblastomas are amenable to surgical resection and anatomical location is one potentially limiting factor. Glioblastomas that invade the corpus callosum and cross midline to the contralateral hemisphere, butterfly glioblastomas (bGBMs), are one subgroup of tumors traditionally deemed inoperable.

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The impact of aneurysm location on incidence and etiology of hyponatremia following subarachnoid hemorrhage  Voir?

Hyponatremia is the most common electrolyte abnormality in patients with aneurysmal subarachnoid hemorrhage (aSAH). The syndrome of inappropriate antidiuretic hormone secretion (SIADH) and cerebral salt wasting (CSW) are the most common etiologies. Whether or not the location of the ruptured aneurysm is associated with the etiology of hyponatremia is unknown. We sought to determine whether or not the incidence of SIADH and CSW after aSAH differ based on aneurysm location.

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Risk factors associated with readmission & reoperation in patients undergoing spine surgery  Voir?

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Adult patients with pneumococcal meningitis at a neurosurgical neurological center. Different predisposing conditions?  Voir?

In previous studies of pneumococcal meningitis in adults within general hospitals or national cohorts, the most common predisposing conditions are otitis media, sinusitis, pneumonia, immunosuppression, alcoholism, and diabetes. The epidemiology of pneumococcal meningitis is changing due to the use of vaccines in childhood, and antibiotic resistance has increased.

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Usefulness of FDG-PET in comparison with methionine-PET in differentiating solid hemangioblastoma from adult cerebellar tumors  Voir?

Among adults with posterior fossa tumors, intraaxial location of the tumors is less common than extraaxial. Moreover, the differential diagnosis of a single cerebellar tumor in adult is sometimes difficult by conventional MRI. We aimed to report the findings of PET using FDG and methionine in adult patients with intraaxial and solitary metastatic brain tumors.

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Risk factors of postoperative sacroiliac joint pain for posterior lumbar surgery:An at least 2-year follow-up retrospective study  Voir?

A retrospective study was conducted to clarify the risk factors of postoperative sacroiliac joint pain (SIJP) for posterior open lumbar surgery.
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Supernumerary abducens nerves: a comprehensive review  Voir?

Branching and/or replication of the abducens nerve is not an uncommon occurrence. While numerous variations have been documented, the rarest forms are duplicated or triplicated nerves, where multiple nerve roots originate from the brain stem, travel intracranially and attach to the lateral rectus as separate entities. Herein, we will review the literature on variations found, discuss current hypotheses and clinical relevance, and propose future studies. Neurosurgeons should be aware of such nerve variants when viewing imaging or operating in the regions traversed by the abducens nerve.

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Medical Malpractice in Neurosurgery: A Comprehensive Analysis  Voir?

Neurosurgeons face the highest probability of facing a medical malpractice claim of any specialist. Here, we perform the first specialty-wide review of malpractice claims in neurosurgery using a well-established, national, online legal database.
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Observation of the effects of different surgical treatments on unilateral masticatory muscle spasm  Voir?

Unilateral masticatory muscle spasm is a rare disease without a generally accepted and efficacious treatment plan.
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Sagittal alignment as predictors of of adjacent segment disease after Lumbar transforaminal inter-body fusion  Voir?

The study was carried out to explore the diagnostic value of sagittal measurement for adjacent segment disease after Lumbar transforaminal inter-body fusion(TLIF).
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Microsurgical treatment of ruptured intracranial aneurysms in sub-Saharan Africa: a series of 102 consecutive cases treated in Senegal  Voir?

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A novel minimally invasive treatment strategy for acute traumatic epidural hematoma: endovascular embolization combined with drainage surgery and use of urokinase  Voir?

Hematoma evacuation is regular treatment for acute traumatic epidural hematoma (ATEDH) patients meeting with surgery indications. However, it is an invasive approach performed under general anesthesia. Here, a novel minimally invasive method of endovascular embolization with subsequent drainage surgery and use of urokinase was established to treat ATEDH under local anesthesia.

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Cost-effectiveness of endoscopic versus microscopic transsphenoidal surgery for pituitary adenoma  Voir?

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A novel dissection method using a flexible neuroendoscope for resection of tumors around the aqueduct of Sylvius: A case report  Voir?

Flexible endoscopes have both a wide range of movement and a wide field of view and are thus widely used for endoscopic third ventriculostomy and biopsy. However, tumor resection using flexible endoscopes has scarcely been reported, likely owing to their single port, which has a diameter of 1.2–2.0 mm. Furthermore, flexible endoscopes do not allow some of the basic neurosurgical manipulations, especially sharp dissection with counter tension. Additionally, the position of the forceps and coagulators is fixed within the endoscope.

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Postoperative Gamma Knife radiosurgery for cavernous sinus-invading growth hormone-secreting pituitary adenomas  Voir?

We aimed to determine the long-term effects of Gamma knife radiosurgery (GKS) on remnants in the cavernous sinus (CS) after transsphenoidal surgery (TSS) for acromegaly and to identify its possible adverse effects.
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The relationship between hematoma and pachymeninges in an interdural hematoma: diagnosis and surgical strategy  Voir?

The exact location of a hematoma in relation to the pachymeninges contributes to typical radiographic presentations. However, because of the complexity of hematoma evolution and neomembrane formation, an unexpected intraoperative finding may lead to a change of surgical strategy. Besides, the concentration of hemoglobin and its degradation products, the integrity of red blood cells (RBCs), and the infiltration of fibroblasts, polymorphonuclear neutrophils, and macrophages are factors that affect the imaging characteristics on computed tomography (CT) and magnetic resonance imaging (MRI) as the hematoma ages.

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Intraoperative monitoring of the integrity of the anterior visual pathways: a methodological review and meta-analysis  Voir?

Diverse methods have been developed for intraoperative monitoring of the integrity of the visual pathways. We performed a review of the literature to determine the methodology of each technique as well as their recent development. The predictive power of each eligible technique was determined based on a meta-analysis.

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Corrigendum to ‘Image Guidance to Aid Pedicle Screw Fixation of a Lumbar Fracture-Dislocation Injury in a Toddler’ [World Neurosurgery 105 (2017) 1041.e15-1041.e17]  Voir?

The authors regret the error in the misspelling of an author's name Jonathan Nakhla and have corrected it.
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Small cell glioblastoma of the sella turcica region: a case report and review of the literature  Voir?

Glioblastomas in the sellar region are very rare; in most cases, the tumor originates from the optic nerve/optic chiasm. Only 4 cases of sellar glioblastoma with a non-optic origin have been reported. We present such a case with detailed clinical, imaging and histopathological information. A review of similar published cases is also presented.

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Pediatric non-missile penetrating head injury, case series and literature review  Voir?

Pediatric non-missile penetrating head injury (NMPHI) is usually accidental attributed mainly to the softer skulls of growing children. However, it is a rather rare entity and therefore no consensus exists regarding treatment, in order to effectively prevent the immediate and long-term complications. Throughout the literature practice, essentials are mostly discussed in case reviews and case series in general population. No data originating from randomized studies are available due to ethical and practical limitations.

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Risks of endoscopic temporal ventriculocisternostomy for isolated lateral ventricle: Anatomical surgical nuances  Voir?

Entrapment of the temporal horn, known as isolated lateral ventricle (ILV), is a rare type of noncommunicating focal hydrocephalus, and its standard treatment has not been established. Here, we report two cases of endoscopic surgery for ILV, and highlight the anatomical surgical nuances to avoid associated surgical risks.

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Delayed traumatic aortic pseudoaneurysm formation causing vertebral body erosion and back pain: case report and literature review  Voir?

Aortic pseudoaneurysms are a rare cause of chronic back pain, usually due to compression of adjacent neurovasculature. It is uncommon for patients with pseudoaneurysms of the abdominal aorta to present in a delayed fashion after initial traumatic injury.
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Posterior Lumbar Interbody Fusion With 3D-Navigation Guided Cortical Bone Trajectory Screws for L4/5 Degenerative Spondylolisthesis: 1-Year Clinical and Radiographic Outcomes  Voir?

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Transtentorial Distortion Syndrome: A consistent complication following lateral and fourth ventricular shunting in adults  Voir?

Complex hydrocephalus affecting lateral and fourth ventricles separately is occasionally managed with CSF diversion via supra- and infra-tentorial ventricular catheters. The optimal configuration to reduce complications is currently unknown in adults. We describe a consistently similar clinical presentation of patients with complex hydrocephalus and a fourth ventricle separately drained by infra-tentorial shunt insertion.

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Surgical treatment of spinal synovial cysts in the elderly: Symptoms, treatment course, and outcome in patients over 75 years  Voir?

The ongoing aging of our society leads to a rising number of elderly patients with progressive degeneration of the spine, associated with synovial cysts. In the elderly, surgical treatment may be particularly challenging because of comorbidities.
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The Effect of Steroids on Complications, Readmission, and Reoperation After Posterior Lumbar Fusion  Voir?

The effects of chronic corticosteroid therapy on complications, readmission, and reoperation after posterior lumbar fusion (PLF) remains under-investigated and was examined to determine differences in outcomes.
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Intradural - extramedullary cervical cord lipoma: Case report and literature review  Voir?

Spinal lipomas are generally thought to occur as a result of failed primary neurulation. Failed primary neurulation allows invasion of mesenchymal tissue of mesodermic origin into the neural structure, leading to the formation of a spinal lipoma. Despite most spinal lipomas being regarded as the result of failed primary neurulation, some confusion in terms of the embryogenesis of spinal lipomas remains. Recently, a novel classification of spinal lipomas based on embryonic changes seen during primary and secondary neurulation was has been proposed.

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Enterprise deployment through a PulseRider to treat an anterior communicating artery aneurysm recurrence  Voir?

PulseRider (Pulsar Vascular, Los Gatos, CA, USA) is a new endovascular device designed to treat wide neck bifurcation intracranial aneurysms. Deployment of a stent through a PulseRider to treat an aneurysm’s recurrence has never been described before.
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Fusion, Failure, Fatality: Long-term Outcomes after Surgical versus Nonoperative Management of Type II Odontoid Fracture in Octogenarians  Voir?

Type II odontoid fracture is a highly morbid injury among octogenarians, with 41% one-year mortality. Our objective was to assess long-term fusion, complication, and survival rates.
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Unruptured versus Ruptured AVMs: Outcome analysis from a multicentric consecutive series of 545 surgically treated cases  Voir?

Recent literature strongly challenged indications to perform preventive surgery in unruptured AVM. claiming that invasive AVM treatment is associated with a significant risk of complications and thus conservative management may be a preferable alternative in many patients. On the other hand, the recent improvement of surgical instrumentation and treatment strategies (both surgical and interventional) yielded much better outcomes than those achieved only a decade ago. Therefore, even among the specialists, a wide variety of opinions, concerning the treatment of unruptured AVM, can be found.

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Technical Note: Robotic-guided bi-hippocampal and bi-parahippocampal depth placement for responsive neurostimulation in bitemporal lobe epilepsy  Voir?

Patients with bitemporal lobe epilepsy are generally not considered for surgical resection. Fortunately, responsive neurostimulation proves another avenue for the management of this challenging disease process. In conjunction with our epileptologist, we consider responsive neurostimulation for patients who have clinical features of temporal lobe epilepsy without clear localization on imaging and stereo-EEG.

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Cerebral hyperperfusion syndrome after endovascular reperfusion therapy in a patient with acute internal carotid artery and middle cerebral artery occlusions  Voir?

Cerebral hyperperfusion syndrome (CHS) is known to be a rare but devastating complication of carotid artery revascularization. Because patients with acute ischemic stroke due to acute major cerebral and/or cervical artery occlusion treated with endovascular reperfusion therapy may have impaired autoregulation in the cerebral vasculature, these patients may also develop CHS. Despite the growing number of endovascular reperfusion procedures for acute ischemic stroke, this complication has only rarely been reported.

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Efficacy of the biomedical glue sling technique versus the traditional technique for microvascular decompression for hemifacial spasm with refractory hypertension  Voir?

Microvascular decompression (MVD) is useful treatment for Hemifacial spasm (HFS) with refractory hypertension (RHTN). Biomedical glue sling technique is a new method for MVD. In this study, we retrospectively compared the outcome of biomedical glue sling technique with traditional technique in MVD for HFS with RHTN.

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Epidemiology and Management of Spinal Trauma in Children and Adolescents Under 18 Years Old  Voir?

Retrospective study.
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Rupture of Intra-ventricular Hydatid Cyst: The Camalote Sign  Voir?

Only a few cases of intraventricular hydatid cysts have been described. The Camalote or waterlily sign is described when there is detachment of the endocyst membrane, resulting in a floating appearance like a waterlily. This sign has been described most commonly in hepatic cysts. Here, we describe the camalote sign in an iatrogenically ruptured intraventricular hydatid cyst. Rupture of an intraventricular hydatid cyst poses the threat of widespread dissemination and is described in our case.

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A novel technique for cervical facet joint hyperplasia-spondylotic radiculopathy by laminar and lateral mass screw co-fixations  Voir?

To describe the novel technique and report the outcomes of cervical spondylotic radiculopathy caused by facet joint hyperplasia treated with minimally invasive surgery by laminar and lateral mass screw co-fixations.
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Predictors of Hospital Length of Stay and 30-Day Readmission in Cervical Spondylotic Myelopathy Patients: An Analysis of 3057 Patients Using the ACS-NSQIP Database  Voir?

Hospital length of stay (LOS), 30-day readmission rate, and other metrics are increasingly being used to evaluate quality of surgical care. The factors most relevant to cervical spondylotic myelopathy (CSM) are not yet established.
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Posterior Cervical Laminectomy Results in Better Radiographic Decompression of Spinal Cord Compared to Anterior Cervical Discectomy and Fusion  Voir?

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Is there an indication of intraoperative MRI in subtotal resection of glioblastoma? – A multicenter retrospective comparative analysis  Voir?

Surgery in patients with highly eloquent glioblastoma (GB) remains challenging.
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Outcome of transforaminal epidural steroid injection according to the severity of cervical foraminal stenosis  Voir?

Cervical transforaminal epidural steroid injection (TFESI) is considered one of the most effective treatments for radicular pain induced by cervical foraminal stenosis.
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The Optimal Treatment Options of Septated Chronic Subdural Haematoma – A Retrospective Comparison of Craniotomy versus Endoscopic-assisted Burr-hole Craniostomy  Voir?

To complete a retrospective comparison of endoscope-assisted burr-hole craniostomy (EBHC) and craniotomy in the treatment of septated chronic subdural hematoma (SCSH).
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Preoperative assessment of craniopharyngioma adherence: MRI findings correlated with the severity of tumor attachment to the hypothalamus  Voir?

Craniopharyngioma (CP) adherence represents a heterogeneous pathological feature that critically influences the potentially safe and radical resection.
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Traumatic Fractures of the Cervical Spine: Analysis of Changes in Incidence, Etiology, Concurrent Injuries and Complications Among 488,262 Patients from 2005-2013  Voir?

The etiologies and epidemiology of traumatic cervical spine fracture have not been described with sufficient power or recency. Our goal is to describe demographics, incidence, etiology, spinal cord injuries (SCIs), concurrent injuries, treatments, and complications of traumatic cervical spine fractures.

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The Effect of Obesity on Clinical Outcomes Following Minimally Invasive Spine Surgery: A Systematic Review and Meta-analysis  Voir?

Obesity is associated with increasing morbidity and mortality in many prevalent diseases, especially for lumbar degenerative disease. The relationship between minimally invasive spine (MIS) surgery and perioperative adverse events in obese patients with lumbar degenerative disease has not been well evaluated.

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Comparision of results between posterior fossa decompression with and without duraplasty for the surgical treatment of Chiari malformation Type I:a systematic review and meta-analysis  Voir?

Posterior fossa decompression without (PFD) or with duraplasty (PFDD) for the treatment of type 1 Chiari malformation (CM-I) is controversial. We thus did a systematic review and meta-analysis of studies to assess the effect on clinical and imaging improvement, operative time, complications and recurrence rate between PFD and PFDD in patients with CM-I.

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Anterior transdiscal axial screw fixation for subaxial cervical spine: A biomechanical study  Voir?

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Comparison of clinical and radiographic outcomes for posterior fossa decompression with and without duraplasty for treatment of pediatric Chiari I malformation: a prospective study  Voir?

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Atlantooccipital Rotatory Dislocation: A Case Report and Systematic Review  Voir?

Atlanto-occipital rotatory dislocation (AORD) has been rarely reported in the literature; for this reason, the clinical-radiological characteristics of this injury are not well described.
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Neuroendoscopic Treatment of Cystic Craniopharyngiomas. A Case Series with Systematic Review of the Literature  Voir?

Total removal of craniopharyngiomas is burdened by high morbidity. In cases of a cystic or mixed craniopharyngioma, when the symptoms are caused by the cystic component of the tumor, a less invasive surgical approach aiming at cyst drainage may be recommended. Here we report our experience with intraventricular neuroendoscopy, describing our clear-cut surgical technique, and analyzing results in the context of literature data.

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Clinical characteristics of lumbosacral spinal dural arteriovenous fistula (DAVF)–comparison to thoracic DAVF  Voir?

Spinal dural arteriovenous fistula (DAVF) occurs at any spinal level but the clinical characteristics of lumbosacral DAVF have not been well documented. Purpose of this study was to evaluate clinical characteristics of lumbosacral DAVF and compare these features to those in thoracic DAVF.
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Correlation between contrast time-density time on digital subtraction angiography and flow: an in vitro study.  Voir?

and Purpose Digital subtraction angiography (DSA) provides an excellent anatomic characterization of cerebral vasculature, but hemodynamic assessment is often qualitative and subjective. Various clinical algorithms have been produced to semi-quantify flow from data obtained from DSA, but few have tested these against reliable flow values.

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Effectiveness of a decision-making protocol for the surgical treatment of lumbar stenosis with Grade 1 degenerative spondylolisthesis  Voir?

The addition of fusion to decompression for stenosis with Grade I degenerative spondylolisthesis is a controversial topic, and the question remains if fusion provides any real benefit to the patient that warrants the increased healthcare utilization and perioperative morbidity. In addition, there is no consensus on indications for the use of fusion over decompression alone.

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Effects of low bone mineral status on biomechanical characteristics in idiopathic scoliotic spinal deformity  Voir?

Low bone mass in adolescent idiopathic scoliosis patients has been well reported. Poor bone quality was regarded as a new and unique prognostic factor in aggravating the curve progression. However, the potential biomechanical correlation between them remains unclear.
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Retrosigmoid intradural suprameatal-inframeatal approach for complete surgical removal of a giant recurrent vestibular schwannoma with severe petrous bone involvement: technical case report  Voir?

Surgical removal of giant vestibular schwannomas with severe petrous bone involvement remains challenging due to the high risk of complications. The retrosigmoid intradural suprameatal-inframeatal approach (RISIA) allows for safe exposure extending from Meckel’s cave to the petrous internal carotid artery (ICA).

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The treatment of a spontaneous dissecting aneurysm in the extracranial vertebral artery with covered-stent: a case report  Voir?

A 13-year-old boy with a spontaneous vertebrobasilar artery dissecting aneurysm (VADA) in the extracranial artery, which was only 1 mm away from the initial segment of subclavian artery, was successfully treated with a covered-stent to block the artery of the VADA. Our experience indicates that this is a fast, reliable, effective and economical technique, particularly suitable for surgeries in settings with limited resources.

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Risk factors for the rupture of intracranial aneurysms using CT angiography  Voir?

To study the clinical and morphological characteristics associated with risk factors for the rupture of intracranial aneurysms (IAs).
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Are antiplatelet and anticoagulants drugs a risk factor for bleeding in mild traumatic brain injury?  Voir?

facing mild traumatic brain injury (mTBI) clinicians must decide whether to perform a CT scan to detect a potential intracranial hemorrhage.Many useful guidelines have been developed for general population, but there is no general consensus about the best practice to adopt when dealing with patients on antiplatelet or anticoagulation drugs. The relatively recent introduction of new anticoagulants and second generation antiplatelet drugs poses new challenges in this field. There is no data in the literature about the relative risk of intracranial bleeding in such categories.

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Low-grade glioma with foci of early transformation does not necessarily require adjuvant therapy following radical surgical resection  Voir?

Low-grade glioma (LGG) is a slow-growing tumour often found in young adults with minimal or no symptoms. As opposed to true ‘low-grade’ lesions like dysembryoplastic neuroepithelial tumours (DNETs), they are associated with continuous growth and inevitable malignant transformation.
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Whats new in Spinal Coccidioidomycosis?  Voir?

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Nerve transfers in patients with Brown Sequard pattern of spinal cord injury: Report of 2 cases  Voir?

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Mammillothalamic and Mammillotegmental Tracts as New Targets for Dementia and Epilepsy Treatment  Voir?

Very recently, neuromodulation through deep brain stimulation (DBS) has appeared as a new surgical procedure in the treatment of some types of dementia and epilepsy. The mammillothalamic and the mammillotegmental tracts are involved among the new targets. To our knowledge, a review article focused specifically on these mammillary body efferents is lacking in the medical literature. Their contribution to memory is, regrettably, often overlooked. There is evidence that mammillary bodies can contribute to memory independently from hippocampal formation, but the mechanism is not yet known.

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Decompressive craniectomy for spontaneous intracerebral hemorrhage: a systematic review and meta-analysis  Voir?

Spontaneous intracerebral hemorrhage (sICH) is a devastating disease with high mortality and morbidity, and application of decompressive craniectomy (DC) in sICH is controversial. We conducted a systematic review to verify the effect of DC on improving outcome in sICH.
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C2 body as the ‘keystone’ in management of C1-C2-C3 dislocation secondary to congenital absence of posterior element: a case report  Voir?

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Readmissions in Anticoagulated Intracranial Hemorrhage Patients: A Retrospective Review  Voir?

The objective of this study was to determine the effect of Direct Oral Anticoagulants (DOACs) when compared to warfarin, on the 30-day readmission rates in patients with traumatic intracranial hemorrhage (ICH).
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Cerebral venous sinus thrombosis following second transsphenoidal surgery——report of a rare complication and review of literature  Voir?

Cushing's disease, induced by pituitary adrenocorticotropic hormone (ACTH) secreting adenomas, is associated with high risk factors of stroke. At present, transsphenoidal surgery remains the first line of therapy. Cerebral venous sinus thrombosis (CVST) is an uncommon form of stroke with variable presentations but, to date, there have been no reports of its occurrence in Cushing's disease patients following surgery.

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Overcoming End-to-End Vessel Mismatch During STA-Radial Artery-M2 Interposition Grafting for Cerebral Ischemia: The Tapering Technique  Voir?

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Post-surgical Cavity Evolution after Brain Metastases Resection: How Soon Should Postoperative Radiosurgery Follow?  Voir?

Postoperative stereotactic radiosurgery (SRS) to the cavity following resection of brain metastases (BM) improves local control (LC). We hypothesized that significant cavity constriction would take place from the immediate postoperative period to the time of SRS and aimed to elucidate optimal treatment timing.

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Efficacy of using intermediate screws in short-segment fixation for thoracolumbar fractures: a meta-analysis of randomized controlled trials  Voir?

Some studies have reported that the conventional intersegmental pedicle screws (four-screw fixation, ‘4S’) device for thoracolumbar fractures was associated with inadequate reduction of fractured vertebrae, insufficient correction of kyphosis, and implant failure. Recently, a series of biomechanical studies confirmed that the addition of intermediate fixation screws (six- screw fixation, ‘6S’) could provide stronger fixation and better reduction of fractured vertebrae. Nevertheless, the clinical and radiological efficacy of the additional intermediate screws remains unclear.

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Long term follow up of Metastatic Epidural Spinal Cord Compression (MESCC) patients from breast cancer treated with surgery followed by radiotherapy  Voir?

Aim of this study was to evaluate the role of surgery plus radiotherapy in Metastatic Epidural Spinal Cord Compression (MESCC) breast cancer (BC) patients with a follow-up longer than 10 years.
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Dwell Time Of Stentriever Influences Complete Revascularisation And First Pass Tici3 Revascularisation In Acute Large Vessel Occlusive Stroke  Voir?

In acute ischemic stroke with large vessel occlusion, the interaction between the clot retriever and the stent is critical for achieving successful recanalization. The ideal time of stent deployment (dwell time, DT) to improve revascularization is currently unknown., We systematically analysed the effect of different DT on final angiographic and clinical outcome of of patients who underwent mechanical thrombectomy.

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Neurosurgery in octogenarians: a prospective study on perioperative morbidity, mortality and complications in elderly patients  Voir?

The aging population in industrialized countries shifts the age limit for neurosurgical interventions towards increasingly older patients. This study investigates whether octogenarians (≥80 years) stand out in outcome and incidence of perioperative complications.
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Evaluation of the use of calcium phosphate cement for aesthetic neurosurgical cranial reconstruction  Voir?

The authors evaluated whether newly developed calcium phosphate cement (CPC), mounted around the titanium plates, is useful for aesthetic cranial reconstruction by using two methods.
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Normal pressure hydrocephalus shunt patients have fewer complications than other shunt patients  Voir?

Ventriculoperitoneal (VP) shunting is a well-established therapy for hydrocephalus. However, complications are frequent. The incidence of idiopathic normal pressure hydrocephalus (NPH) rises with the aging of the population. We evaluated the functional status of patients and the classification of complications associated with VP shunt procedures in our center.

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Surgical outcomes after segmental limited surgery for adjacent segment disease: the consequences of makeshif  Voir?

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Unplanned intraoperative extubations in pediatric neurosurgery: analysis of case series to increase patient safety  Voir?

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The Impact of Chronic Kidney Disease on Post-Operative Outcomes in Patients Undergoing Lumbar Decompression and Fusion  Voir?

Little is known of the impact of pre-operative chronic kidney disease (CKD) on post-operative complications in patients undergoing lumbar arthrodesis. The aim of this study is to determine whether pre-operative CKD is associated with inferior peri-operative outcomes.
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Endoscopic Approach to Clival Chordomas: The Northwestern experience  Voir?

Chordomas are rare primary bone tumors with a low-grade histology but an aggressive clinical behavior characterized by local invasion and recurrence. When occurring in the skull base, their treatment is limited by proximity to critical neurovascular structures. Open surgical approaches can carry high morbidity making the development of alternative approaches desirable. We describe our experience with endoscopic endonasal approaches to clival chordomas over 13 years.

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Clinical features of precocious, synchronous, and metachronous brain metastases and the role of tumor resection  Voir?

The purpose of this study was to clarify clinical features, outcomes, and the role of tumor resection in precocious, synchronous, and metachronous brain metastases. Methods Brain metastases were found before primary cancer detection in the precocious group, within 2 months after primary cancer detection in the synchronous group, and 2 months or later after primary cancer detection in the metachronous group.

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Suboccipital Decompressive Craniectomy for Cerebellar Infarction: A Systematic Review and Meta-Analysis  Voir?

Suboccipital decompressive craniectomy (SDC) for cerebellar infarction has been traditionally performed with minimal high-quality evidence. The aim of this systematic review and meta-analysis is to investigate the impact of SDC on functional outcomes, mortality, and adverse events in patients with cerebellar infarcts.

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High cervical spinal cord compression associated with anomaly of bilateral vertebral arteries  Voir?

Anomalies of vertebral arteries are rare, and usually detected incidentally. However, very rarely, they can manifest clinical symptoms. We describe such a symptomatic case of high cervical spinal cord compression associated with persistent C2 segmental arteries.
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Impact of Operating Room Environment on Postoperative Central Nervous System Infection in a Resource-Limited Neurosurgical Center in South Asia  Voir?

Postoperative central nervous system infections (PCNSIs) are serious complications following neurosurgical intervention. We previously investigated the incidence and causative pathogens of PCNSIs at a resource-limited, neurosurgical center in south Asia. This follow-up study was conducted to analyze differences in PCNSIs at the same institution following only one apparent change: the operating room air filtration system.

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Differentiating between Primary Central Nervous System Lymphomas and Glioblastomas: Combined Use of Perfusion- and Diffusion- Weighted Magnetic Resonance Imaging  Voir?

The purpose of this study was to determine whether combined diffusion-weighted imaging (DWI) and dynamic susceptibility contrast-enhanced perfusion-weighted imaging (PWI) magnetic resonance imaging (MRI) can be used to differentiate between common malignant brain tumors, including lymphomas and high-grade gliomas.

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Anatomical study of the extracranial needle trajectory using the Hartel technique for percutaneous treatment of trigeminal neuralgia  Voir?

The aim of this study was to describe the anatomical trajectory of the extracranial needle for percutaneous rhizotomy and correlate this with structures at risk during such a procedure.
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An evaluation of commonly used external ventricular drain securement metho ds in a porcine model; recommendations to improve practise  Voir?

External ventricular drain (EVD) dislodgement is common and leads to significant morbidity and mortality. Many securement techniques to prevent this are described. There are, however, no objective studies comparing them. This study aimed to determine the most secure method of securing an EVD.
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Surgical revascularization for children with moyamoya disease: a new modification to the pial synangiosis  Voir?

To summarize the therapeutic efficacy of modified pial synangiosis in children with moyamoya disease and our experience with this method.
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The “July effect” on the care for aneurysmal subarachnoid hemorrhage  Voir?

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Presacral Tarlov cyst as an unusual cause of abdominal pain: new cases and literature review  Voir?

The etiology of abdominal pain is sometimes difficult to be defined. A presacral Tarlov cyst is an unusual cause of abdominal pain. The unusual location of a presacral Tarlov cyst can lead to misdiagnosis and inappropriate treatment. To guide the appropriate diagnosis and treatment, we review the cause, clinical presentations, radiological features and management options of this extremely rare lesion.

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Pituitary Ependymoma: A Case Report and Review of the Literature  Voir?

The case of pituitary ependymoma is exceptionally rare. Its etiology, clinical presentation, radiological feature and treatment strategy are still a matter of debate. Only 7 cases with limited data were reported in human in English literature, and now we described another case of pituitary ependymoma , systematically reviewed previously reported cases and described its’ potential etiology, clinical presentation, radiological features, pathology, immunohistochemical analysis and ultrastructural examinations.

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Epidural steroids at closure post-microdiscectomy/laminectomy for reduction of post-operative analgesia: systematic review and meta-analysis  Voir?

This review assessed the efficacy of epidural steroid administration on the reduction of pain, hospital stay time and use of opioid analgesics postoperatively.
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Prognostic factors for the survival outcome of bilateral thalamic glioma: An integrated survival analysis  Voir?

The aim of this study was to perform an integrated survival analysis of patients with BTG and to assess the influence of various prognostic factors on overall survival.
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Regression of giant calcified thoracic disc and spinal cord compression following thoracic laminectomy and posterior instrumented fusion  Voir?

A 55 year old full time employed lady presented with urinary urgency and occasional lower extremity numbness and tingling with motor function preservation. CT and MRI revealed a 20mm x 9mm T10-T11 calcified disc (Figure A, B, C). Anterior and posterior approaches were discussed with the patient along with associated risks such as CSF leak due to possible intradural extension and small but possible risk of new onset motor deficit following disc removal. Considering her almost intact neurological function and to avoid slight albeit realistic morbidity from attempted discectomy regardless of an anterior transthoracic or posterolateral approach, a strategy consisting of a wide long segment T10-T11 laminectomy and T9-T12 posterior instrumented fusion was performed with the assumption that micro motion elimination through a fusion will eliminate dynamic compression from spinal cord draping over the anterior calcified disc fragment.

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Development of Patient-Spesific 3d-Printed Dural Venous Models For Preoperative Planning  Voir?

Despite significant improvement in clinical care, operative strategies, and technology, neurosurgery is still risky, and optimal preoperative planning and anatomical assessment are necessary to minimize risks of serious complications. Our purpose is to document of dural venous sinuses (DVS) and its variations were identified during routine 3D venography created through three dimensional (3D) models for teaching and learning of complex cerebral anatomy.

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How early can we perform cranioplasty for traumatic brain injury after decompressive craniectomy? A retrospective multi-center study  Voir?

Decompressive craniectomy (DC) is used to treat intractable intracranial hypertension following severe traumatic brain injury (TBI). Cranioplasty (CP) is typically performed weeks or months later. However, the optimal timing for CP is unknown. We aimed to determine the earliest possible time point for CP.

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Infection Incidence Associated with External Ventriculostomy Placement: A Comparison of Outcomes in the Emergency Department, Intensive Care Unit, and Operating Room  Voir?

External ventricular drain (EVD) placement is a common neurosurgical procedure used to control acute hydrocephalus and other neurosurgical complications. The infection and complication rates reported in the literature are highly variable, and iatrogenic factors determine the outcome of drain placement. We examined the impact of the setting of EVD placement (emergency department [ED] vs. intensive care unit [ICU] vs. operating room [OR]) and the experience of the operating surgeon on the infection rate, complication rate, EVD replacement, eventual placement of a ventriculoperitoneal shunt, and the need for further surgical intervention.

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A Case of Subarachnoid Hemorrhage Caused by Tuberculous Aneurysm  Voir?

In this paper, we report a case of intracranial tuberculum with adjacent intracerebral inflammatory aneurysm, and include a brief discussion of the developmental mechanism of these pathologies. A 28-year-old man presented with sudden onset of severe headache. He was diagnosed with h pulmonary tuberculosis 8 year ago, and had been treated with anti-tuberculosis medications for 6 months. Head computed tomography (CT) showed a small hematoma in the left Sylvian fissure with subarachnoid hemorrhage.

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Brainstem cavernous malformations: surgical indications based on the natural history and surgical outcomes  Voir?

Cavernous malformations (CMs) are uncommon lesions occurring in the central nervous system (CNS), with an incidence of approximately 0.5% in the general population and constituting 5-10% of all intracranial vascular malformations. Among CMs, prevalence within the brainstem as reported in the literature has ranged from 4 to 35%. With their precarious location and potentially devastating clinical events, brainstem CMs have attracted attention from neurosurgeons, and with their unrelenting efforts, the microsurgical techniques to treat these lesions in the brainstem have greatly improved in recent decades.

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Effect of Progesterone on Cerebral Vasospasm and Neurobehavioral Outcomes In A Rodent Model of Subarachnoid Hemorrhage  Voir?

Subarachnoid hemorrhage (SAH) induces widespread inflammation leading to cellular injury, vasospasm and ischemia. Evidence suggests that progesterone (PROG) can improve functional recovery in acute brain injury due to its anti-inflammatory and neuroprotective properties, which could also be beneficial in SAH. We hypothesized that PROG treatment attenuates inflammation mediated cerebral vasospasm and microglial activation, improves synaptic connectivity, and ameliorates functional recovery after SAH.

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Isolated Transverse Process Spinal Fractures increase the likelihood of incurring visceral and pelvic injuries: A retrospective review at a level-1 trauma center  Voir?

Although isolated transverse process fractures (ITPF) do not confer any inherent risk of compromised spinal stability, there is growing interest in their overall prognostic significance. As a proxy for localized or directional forces in high energy traumatic mechanisms, ITPF may serve as an indicator for the presence of other coexisting traumatic injuries. Specific injuries may be predicted by the presence of ITPF at specific spinal levels, but few studies have examined this in depth and may not account for confounding variables.

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Tentorial Meningiomas: Reappraisal of Surgical Approaches and Their Outcomes  Voir?

Tentorial meningiomas are notorious for their critical location. Selection of a suitable approach that exposes the multi-compartmental growth of tumor is important for a complete and safe resection. This paper discusses about various operative approaches and their overall surgical outcome.
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Cryopreservation of Autologous Cranial Bone Flaps for Cranioplasty: A Large Sample Retrospective Study  Voir?

To clarify the clinical outcomes of cranioplasty with cryopreserved bone flaps and identify risk factors related to bone flap infection and resorption after cranioplasty with cryopreserved bone flaps.
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Prosthetic Replacement of the Ocular Surface Ecosystem (PROSE) treatment of ocular surface disease following skull base tumor resection  Voir?

Prosthetic Replacement of the Ocular Surface Ecosystem (PROSE) treatment is an effective, non-surgical therapeutic option for patients with ocular surface disease related to cranial nerve deficits secondary to skull base tumor resection. This case series describes the impact of PROSE treatment in patients with symptomatic exposure keratopathy or neurotrophic keratitis after skull base tumor surgery. All patients improved symptomatically and functionally with PROSE treatment, and have had sustained improvement for as long as 3 years.

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Results of a Policy of Fast Tapering of Steroids After Resection Surgery in Glioblastoma  Voir?

Corticosteroids are routinely used to treat brain tumors. Although steroids have an immediate clinical benefit, their use can lead to a number of relevant complications, and a negative association with overall survival has been shown in glioblastoma (GBM) patients. There is no evidence in the literature regarding the ideal dose. We assessed the use of steroids in patients with GBM after resection surgery.

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Adolescent Idiopathic Scoliosis Surgery by a Neurosurgeon: Learning Curve for Neurosurgeons  Voir?

To determine a neurosurgeon’s learning curve of surgical treatment for adolescent idiopathic scoliosis (AIS) patients.
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Proximal Stenosis Is Associated with Rupture Status in Middle Cerebral Artery Aneurysms  Voir?

Hemodynamic factors impact cerebral aneurysm development and progression. Parent vessel architectural features, such as caliber, curvature, and angle, can affect downstream pressure and shear stress.
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The Correlation Between Vertical Laminar Fractures and the Severity of Associated Burst Fractures  Voir?

Patients with laminar fractures have a higher chance of experiencing severe trauma and neurologic deficit. In previous studies, laminar fractures were divided into different types based on the axial plane of computed tomographic scans. No report described the morphology of vertical laminar fractures in the coronal plane. Furthermore, the correlation between a specific type of laminar fracture and the extent of severity of thoracolumbar (TL) burst fractures has rarely been mentioned.

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The Middle Temporal Artery: Surgical Anatomy and Exposure for Cerebral Revascularization  Voir?

The middle temporal artery (MTA) is the proximal medial branch of the superficial temporal artery (STA), supplying the temporalis muscle along with deep temporal arteries. Its use in vascularized flaps for reconstructive and otologic procedures has been described, yet its potential use in neurosurgery is not studied. We report a novel technique for exposing the MTA and evaluated its characteristics for extracranial-intracranial (EC-IC) cerebrovascular bypass.

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Corrigendum to “Intraoperative Ultrasound in Patients Undergoing Transsphenoidal Surgery for Pituitary Adenoma: Systematic Review” [World Neurosurgery 106 (2017) 680-685]  Voir?

The authors regret a typo in the title that should read ‘Intraoperative Ultrasound in Patients Undergoing Transsphenoidal Surgery for Pituitary Adenoma: Systematic Review’.
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Efficacy, Reliability, and Safety of Completely Autologous Fibrin Glue in Neurosurgical Procedures: Single-Center Retrospective Large-Number Case Study  Voir?

Commercially available fibrin glue (Com-FG), which is used commonly worldwide, is produced with pooled human plasma from multiple donors. However, it has added bovine aprotinin, which involves the risk of infection, allogenic immunity, and allergic reactions. We evaluate the efficacy, reliability, and safety of completely autologous fibrin glue (CAFG).

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A Critical Analysis of the Utility of Intra-Operative Angiography  Voir?

Intraoperative digital subtraction angiography (ioDSA) is touted as the “gold standard” imaging evaluation for aneurysm clip constructs. Candid evaluations of its limitations are sparse.
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Exome Sequencing Identifies LOXL2 Mutation as a Cause of Familial Intracranial Aneurysm  Voir?

Genetic risk factors can contribute to the etiology of intracranial aneurysms (IAs), and the genetic predisposition of IAs is largely unknown. Our study aimed to explore the role of rare variations in IA susceptibility.
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Evaluation of Problem- and Simulator-Based Learning in Lumbar Puncture in Adult Neurology Residency Training  Voir?

Lumbar puncture (LP) is an essential part of adult neurology residency training. Technologic as well as nontechnologic training is needed. However, current assessment tools mostly focus on the technologic aspects of LP. We propose a training method—problem- and simulator-based learning (PSBL)—in LP residency training to develop overall skills of neurology residents.

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Assessment of a Novel Adult Cervical Deformity Frailty Index as a Component of Preoperative Risk Stratification  Voir?

To determine the value of a novel adult cervical deformity frailty index (CD-FI) in preoperative risk stratification.
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Resumption of Antithrombotic Agents in Chronic Subdural Hematoma: A Systematic Review and Meta-analysis  Voir?

The clinical decision whether and when to resume antithrombotics in patients with chronic subdural hematomas (CSDH) postoperatively is limited by a lack of quality evidence exploring this topic. Our study aims to assess the available evidence of patient complication outcomes, specifically hemorrhagic and thromboembolic events, following the resumption or non-resumption of antithrombotic agents postoperatively in CSDH patients already on these agents before CSDH.

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Artificial stroke clots: How wide is the gap to the real world?  Voir?

Especially since the establishment of mechanical thrombectomy as part of the standard stroke therapy, artificial thrombi have become important in the training of interventionalists as well as for the development and testing of devices. So far, these in vitro clots lack direct comparisons with ex vivo thrombi. We therefore compared the histological appearance of dynamically produced clots with that of stroke thrombi acquired during mechanical recanalization.

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Subarachnoid Hemorrhage and Readmissions: National Rates, Causes, Risk Factors, and Outcomes in 16,001 Hospitalized Patients  Voir?

The acute complications of aneurysmal subarachnoid hemorrhage (aSAH) often lead to readmissions, which are linked to hospital reimbursement. The national rates, causes, risk factors, and outcomes associated with 30-day and 90-day readmission following aSAH have not previously been reported.
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Does Temperature Increase by Sympathetic Neurolysis Improve Pain in Complex Regional Pain Syndrome? A Retrospective Cohort Study  Voir?

Lumbar sympathetic neurolysis (LSN) is a treatment option for complex regional pain syndrome (CRPS). We examined whether LSN-related temperature changes are associated with clinical outcome and investigated relationships between the outcome of LSN and clinical variables in patients with CRPS-I.
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Risk of Recurrence in Operated Parasagittal Meningiomas: A Logistic Binary Regression Model  Voir?

Parasagittal meningiomas arise from the arachnoid cells of the angle formed between the Superior Sagittal Sinus (SSS) and the brain convexity. In this retrospective study we have focused on factors that predict early recurrence and recurrence times.
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The relationship between intracranial pressure and age – chasing age related reference values  Voir?

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Independent Association Between Pre-Operative Cognitive Status and Discharge Location after Surgery: A Strategy to Reduce Resource use After Surgery For Deformity  Voir?

The aim of this study is to determine if preoperative scores on a screening measure for cognitive status(the Saint Louis Mental Status), were associated with discharge to a location other than home in elderly patients undergoing surgery for deformity.
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Hybrid assistive limb exoskeleton HAL® in the rehabilitation of chronic SCI: Proof of concept, the results of 21 patients  Voir?

The use of mobile exoskeletons is becoming more and more common in the field of spinal cord injury rehabilitation. The hybrid assistive limb exoskeleton (HAL) provides a tailored support depending on the patient’s voluntary drive.
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Anatomic Basis for Minimally Invasive Resection of Intradural Extramedullary Lesions in Thoracic Spine  Voir?

Since the first resections of intradural extramedullary neoplasms, neurosurgeons have tended to preserve as much of the integrity of the spine as possible while ensuring a safe corridor to resect these lesions. A dimensional analysis of intradural lesions superimposed on a dimensional analysis of the thoracic canal would provide the anatomic basis for a minimal access approach. The authors report the results of such an analysis on a series of patients with intradural extramedullary lesions.

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Safety and Efficacy of Single-Stage versus 2-Stage Spinal Fusion via Posterior Instrumentation and Anterior Thoracoscopy: A Retrospective Matched-Pair Cohort Study with 247 Consecutive Patients  Voir?

Posterior-anterior spondylodesis is often used to stabilize the spine in various pathologies. The anterior procedure is often performed via thoracoscopy. It is unclear whether the anterior procedure should be performed immediately after posterior instrumentation or after the patient has convalesced. This retrospective study compared perioperative safety and morbidity in 1-stage versus 2-stage posterior-anterior fusion surgery with a thoracoscopic anterior approach.

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Intradural Extramedullary Bronchogenic Cyst: Clinical and Radiologic Characteristics, Surgical Outcomes, and Literature Review  Voir?

An intradural extramedullary bronchogenic cyst (IEBC) is a congenital malformation and an extremely rare type of endodermal cyst. This study aims to report the clinical and radiologic characteristics and surgical outcomes of IEBCs and to review the available literature.
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Long-Term Efficacy of Initial Microvascular Decompression Versus Subsequent Microvascular Decompression for Idiopathic Hemifacial Spasm  Voir?

Hemifacial spasm (HFS) is a disorder characterized by intermittent, involuntary facial muscle contractions. Microvascular decompression (MVD) is the gold treatment for HFS. The aim of this research was to discuss whether patients undergoing MVD as their initial surgical intervention experience greater spasm control than patients experiencing an MVD performed as a subsequent surgical intervention.

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Percutaneous Endoscopic Lumbar Reoperation for Recurrent Sciatica Symptoms: A Retrospective Analysis of Outcomes and Prognostic Factors in 94 Patients  Voir?

Recurrent symptoms of sciatica after previous surgical intervention is a relatively common and troublesome clinical problem. Percutaneous endoscopic lumbar decompression has been proved to be an effective method for recurrent lumbar disc herniation. However, the prognostic factors and outcomes of percutaneous endoscopic lumbar reoperation (PELR) for recurrent sciatica symptoms were still unknown. The purpose of this study was to evaluate the outcomes and prognostic factors of patients who underwent PELR for recurrent sciatica symptoms.

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Effect of Baroreceptor Sensitivity on Outcomes in Patients with Acute Spontaneous Intracerebral Hemorrhage  Voir?

Reduced baroreflex sensitivity (BRS) has been reported in patients with acute cardiovascular events. We tested the hypothesis that BRS is substantially reduced in patients with spontaneous intracerebral hemorrhage (ICH) and that BRS can predict treatment outcomes.
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Effect of Tranexamic Acid on Prevention of Hemorrhagic Mass Growth in Patients with Traumatic Brain Injury  Voir?

Intracranial hemorrhage is a common complication of traumatic brain injury (TBI). The purpose of this study is evaluation of the effect of tranexamic acid (TXA) on hemorrhagic mass growth in TBI patients.
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Suboccipital Craniotomy Versus Craniectomy: A Survey of Practice Patterns  Voir?

Open surgical access to the posterior fossa traditionally has been achieved by permanent bone removal and remains the mainstay of posterior fossa surgery, although craniotomy is an alternative. Considerable variation exists at both the national and international levels within a variety of neurologic and neurosurgical disciplines. In this study, we surveyed current practice patterns regarding preference of suboccipital craniotomy or craniectomy.

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Management of Primary Bilateral Trigeminal Neuralgia with Microvascular Decompression: 13-Case Series  Voir?

Bilateral trigeminal neuralgia is a relatively rare disease. Microvascular decompression (MVD) is a safe and effective treatment for unilateral trigeminal neuralgia; however, its utility in bilateral trigeminal neuralgia is unclear. Here, we report our experience with MVD in 13 cases of primary bilateral trigeminal neuralgia.

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Does Advanced Age Affect the Outcomes of Stereotactic Radiosurgery for Cerebral Arteriovenous Malformation?  Voir?

Stereotactic radiosurgery (SRS) is generally considered a minimally invasive treatment modality. However, definitive evidence of the efficacy of SRS in the elderly population is still not available.
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Predictive Factors of Headache Resolution After Chiari Type 1 Malformation Surgery  Voir?

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5-ALA-induced fluorescence in leptomeningeal dissemination of spinal malignant glioma  Voir?

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Unilateral Symptomatic Hypertrophic Olivary Degeneration Secondary to Midline Brainstem Cavernous Angioma: A Case Report and Review of the Literature  Voir?

Hypertrophic olivary degeneration (HOD) is a rare phenomenon in the dento-rubro-olivary pathway due to lesion or disruption of the fibers of the Guillain-Mollaret Triangle. Hemorrhage of pontine and midbrain cavernous angiomas rarely can lead to hypertrophic olivary degeneration (HOD) portending neurological deterioration and possible concomitant life-threatening complications; for this reason, it may define a poignant consideration in planning intervention.

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Predicting Prognosis of Patients with Chronic Subdural Hematoma: A New Scoring System  Voir?

Chronic subdural hematoma (CSDH) is a commonly encountered neurosurgical pathology that frequently requires operative intervention. With an increasing ageing demographic, more elderly and comorbid patients will present with symptomatic CSDH. This study evaluated clinical and radiologic factors to create a scoring system to aid prognostication.

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A Submammarian Approach for Cosmetically Improved Implantation of Deep Brain Stimulation Generators  Voir?

Deep brain stimulation (DBS) indications include movement disorders, psychiatric affections, or epilepsy in which patients risk social isolation heightened by abnormal motions or behavioral patterns. Further stigmatization after DBS surgery from head shaving, visible scarring, or disfigurement from bulky lead insertion points should be avoided.

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Multilayer Dura Reconstruction After Thoracoscopic Microdiscectomy: Technique and Results  Voir?

Anterior transthoracic approaches, including thoracoscopic microdiscectomy (TMD), are the preferred techniques for central, broad-based, calcified thoracic disc herniations (TDHs). Dural defects due to manipulation or transdural extension may create a potentially life-threatening subarachnoid-pleural fistula. We evaluate a fast, sutureless technique for reconstructing the dura.

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Influence of Lumbar Lordosis on the Outcome of Decompression Surgery for Lumbar Canal Stenosis  Voir?

Although sagittal spinal balance plays an important role in spinal deformity surgery, its role in decompression surgery for lumbar canal stenosis is not well understood. To investigate the hypothesis that sagittal spinal balance also plays a role in decompression surgery for lumbar canal stenosis, a prospective cohort study analyzing the correlation between preoperative lumbar lordosis and outcome was performed.

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Presentation, Treatment, and Long-Term Outcome of Intrasellar Chordoma: A Pooled Analysis of Institutional, SEER (Surveillance Epidemiology and End Results), and Published Data  Voir?

Chordoma that occurs primarily in the sella turcica is rare and presents unique treatment challenges.
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Training Neurosurgery and Radiation Oncology Residents in Stereotactic Radiosurgery: Assessment Gathered from Participants in AANS and ASTRO Training Course  Voir?

Stereotactic radiosurgery (SRS) represents an expanding approach for neurosurgeons and radiation oncologists. We evaluate educational gaps of senior residents drawn from each specialty as part of a focused SRS course. We also evaluate the strengths and limitations of SRS training in current residency programs of the course residents and faculty.

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Epidermal Growth Factor Receptor Expression Predicts Time and Patterns of Recurrence in Patients with Glioblastoma After Radiotherapy and Temozolomide  Voir?

The aim of this study was to investigate the potential role of epidermal growth factor receptor (EGFR) protein expression in predicting the modality of treatment failure in glioblastoma (GB).
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A Propensity Score Analysis of the Impact of Dexamethasone Use on Delayed Cerebral Ischemia and Poor Functional Outcomes After Subarachnoid Hemorrhage  Voir?

An inflammatory response occurs after aneurysmal subarachnoid hemorrhage (aSAH) and predicts poor outcomes. Glucocorticoids suppress inflammation and promote fluid retention. Dexamethasone is often administered after aSAH for postoperative cerebral edema and refractory headache. Our objective was to examine the impact of dexamethasone use on functional outcomes and delayed cerebral ischemia (DCI) after aSAH.

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Hidden Blood Loss in Anterior Cervical Fusion Surgery: An Analysis of Risk Factors  Voir?

A retrospective study.
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Prognostic Significance of Ultraearly Hematoma Growth in Spontaneous Intracerebral Hemorrhage Patients Receiving Hematoma Evacuation  Voir?

To investigate the association between ultraearly hematoma growth (uHG) and clinical outcome in patients with spontaneous intracerebral hemorrhage (sICH) receiving hematoma evacuation.
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Microsurgical versus Endovascular Treatments for Blood-Blister Aneurysms of the Internal Carotid Artery: A Retrospective Study of 83 Patients in a Single Center  Voir?

Blood-blister aneurysms (BBAs) of the internal carotid artery (ICA) are challenging lesions with high morbidity and mortality. Both surgical and endovascular approaches have been used to treat BBAs; however, little is known about their safety and efficacy.
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Multilevel Spondylolysis Repair Using the “Smiley Face” Technique with 3-Dimensional Intraoperative Spinal Navigation  Voir?

Multilevel spondylolysis is a rare cause of progressive lower back pain, and patients who fail conservative management are treated surgically. Direct repair methods can maintain mobility and lead to decreased morbidity compared with spinal fusion in single-level spondylolysis. In this paper, we present a patient with nonadjacent multilevel spondylolysis who underwent the “smiley face” technique of direct multilevel repair without fusion using 3-dimensional intraoperative spinal navigation.

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Subfrontal Schwannoma: Case report and review of literature  Voir?

We present the case of a 46 year old female that presented with right tinnitus, dizziness and bifrontal headache, progressive, starting two years before. Imaging studies reveals an incidentally neoplastic extraaxial homogeneous appearance tumor on the right anterior skull base. She undewernt surgical treatment with total resection of the tumor by a bicoronal approach. The histopathological study reported schwannoma.Although attributte the origin of schwannomas from the the olfactory nerve is near impossible, once they do not have Schwann cells, intracranial supratentorial schwannomas are mainly located in the anterior skull base.

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Intracranial Pressure–Guided Shunt Valve Adjustments with the Miethke Sensor Reservoir  Voir?

Telemetric intracranial pressure (ICP) monitoring seems to be a promising therapy-supporting option in shunt-treated patients. Benefits become obvious when headaches are unspecific and clinical symptoms cannot be related to possible overdrainage or underdrainage. In this study, we evaluated a new telemetric device to individually adjust shunt valves according to ICP measurements.

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Superselective Thalamotomy in the Most Lateral Part of the Ventralis Intermedius Nucleus for Controlling Essential and Parkinsonian Tremor  Voir?

The minimum and essential thalamic areas for reducing tremor were investigated in cases treated by superselective thalamotomy in the most lateral part of the ventralis intermedius nucleus (mlp-VIM).
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Validation of Prognostic Models to Predict Early Mortality in Spontaneous Intracerebral Hemorrhage: A Cross-Sectional Evaluation of a Singapore Stroke Database  Voir?

Numerous scores have been developed for prognostication of outcomes in intracerebral hemorrhage (ICH). Prediction models must be validated internally and externally before they are considered widely applicable. We aim to independently externally validate and compare 3 prediction models (ICH score, ICH grading scale [ICH-GS], and simplified ICH [sICH]) in our population, which has not been previously done.

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Prevalence, Characteristics, and Long-Term Prognosis of Epilepsy Associated with Pediatric Brain Tumors  Voir?

We investigated the prevalence, onset, characteristics, and long-term course of epilepsy disease in children who underwent surgical intervention for diagnosed brain tumors.
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Spontaneous Intrauterine Depressed Skull Fractures: Report of Two Cases Requiring Neurosurgical Intervention and Literature Review  Voir?

Spontaneous intrauterine depressed skull fractures (IDSF) are rare fractures that often require neurosurgical evaluation and therapy. The majority of reported congenital depressions are secondary to maternal abdominal trauma or instrumentation during delivery. Spontaneous IDSF occur in the setting of uneventful normal spontaneous vaginal delivery (NSVD) or cesarean section, without obvious predisposing risk factors. The etiology and optimal management of spontaneous IDSF remain controversial.

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Symptomatic Vasospasms as a life-threatening complication after transsphenoidal surgery  Voir?

To identify symptomatic vasospasms as a rare complication after pituitary surgery with emphasis on management and outcome.
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Surgery for Herniated Lumbar Disc in Daily Tobacco Smokers: A Multicenter Observational Study  Voir?

To compare clinical outcomes at 1 year following single-level lumbar microdiscectomy in daily tobacco smokers and nonsmokers.
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The Relevance of Simpson Grade Resections in Modern Neurosurgical Treatment of World Health Organization Grade I, II, and III Meningiomas  Voir?

The Simpson grading system has played an important role in surgical resections of meningiomas. The aim of this study was to determine if this grading system predicts meningioma recurrence in a modern cohort of patients with tumors of all World Health Organization grades.
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Neurosurgical Resident Error: A Survey of U.S. Neurosurgery Residency Training Program Directors' Perceptions  Voir?

Efforts to address resident errors and to enhance patient safety have included systemic reforms, such as the Accreditation Council for Graduate Medical Education's (ACGME's) mandated duty-hour restrictions, and specialty-specific initiatives such as the neurosurgery Milestone Project. However, there is currently little data describing the basis for these errors or outlining trends in neurosurgical resident error.

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Postoperative Intravenous Acetaminophen for Craniotomy Patients: A Randomized Controlled Trial  Voir?

To determine whether opioids during the first 24 postoperative hours were significantly altered when receiving intravenous (IV) acetaminophen during that time compared with those receiving placebo (normal saline).
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Ruptured Persistent Trigeminal Artery Causing Direct Cavernous Sinus Fistula Treated with Pipeline Embolization and Minimal Coiling  Voir?

Rupture of a persistent trigeminal artery associated with development of a cavernous sinus fistula in a traumatic setting is rare. These arteries are typically treated with coil embolization of the cavernous sinus.
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Citizens Urge U.S. Food and Drug Administration to Restrict High-Potency Opioids  Voir?

A group of physicians and public health officials has petitioned the U.S. Food and Drug Administration to ban ultra-high dosage unit (UHDU) opioid medications from the market.1 UHDU opioids are those for which the prescribed usage exceeds the daily safe maximum set by the Centers for Disease Control and Prevention: 90 morphine milligram equivalents.2 For example, the authors cite the OxyContin 80-mg tablet: a single pill contains 120 morphine milligram equivalents, surpassing the Centers for Disease Control limit with a single dose.

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Optical Coherence Tomography in the Management of Skull Base Fibrous Dysplasia with Optic Nerve Involvement  Voir?

Fibrous dysplasia (FD) of the skull base can manifest with optic nerve compression. As most patients initially do not experience vision loss, controversy exists whether to proceed with prophylactic surgical decompression or elect for conservative observation. Optical coherence tomography (OCT), a physiologic imaging modality widely used to assess the condition of the retinal nerve fiber layer (RNFL), has been useful in monitoring compressive tumors on the optic nerve. This study evaluated potential use of OCT in management of patients with fibrous dysplasia and optic nerve involvement.

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Predictors of Postoperative Recovery Based on Health-Related Quality of Life in Patients after Degenerative Lumbar Scoliosis Surgery  Voir?

To investigate the factors associated with the recovery process of elderly patients after degenerative lumbar scoliosis surgery.
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Outcomes of Two-Isocenter Gamma Knife Radiosurgery for Patients with Typical Trigeminal Neuralgia: Pain Response and Quality of Life  Voir?

To evaluate the effectiveness and safety of 2-isocenter Gamma Knife surgery (GKS) by reviewing patients with trigeminal neuralgia (TN) from the last 10 years.
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Proposed Treatment Paradigm for Intracranial Chondrosarcomas Based on Multidisciplinary Coordination  Voir?

There was no consensus regarding the treatment of intracranial chondrosarcoma (CSA). The study aimed to evaluate the adverse factors for progression-free survival (PFS) and overall survival (OS) and to propose a treatment strategy for CSA.
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Evolution of Prophylaxis Protocols for Venous Thromboembolism in Neurosurgery: Results from a Prospective Comparative Study on Low-Molecular-Weight Heparin, Elastic Stockings, and Intermittent Pneumatic Compression Devices  Voir?

The incidence of venous thromboembolism (VT) in neurosurgical practice is astonishingly high, representing a major cause of morbidity and mortality. Prophylaxis strategies include elastic stockings, low-molecular-weight heparin (LMWH), and intermittent pneumatic compression (IPC) devices.
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Radiosurgery for Treatment of Renal Cell Metastases to Spine: A Systematic Review of the Literature  Voir?

The incidence of renal cell carcinoma (RCC) continues to increase, and the spine is the most common site for bony metastasis. Radiation therapy is one treatment for spinal RCC metastasis. Stereotactic body radiotherapy (SBRT) is a newer treatment that reportedly has benefits over conventional external beam radiotherapy. This study systematically reviewed the current literature on SBRT for metastatic RCC to spine.

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A Stent-Retrieving into an Aspiration Catheter with Proximal Balloon (ASAP) Technique: A Technique of Mechanical Thrombectomy  Voir?

The best technique for the first attempt at mechanical thrombectomy for acute ischemic stroke is a still matter of debate. In this study, we evaluate the efficacy of a stent-retrieving into an aspiration catheter with proximal balloon (ASAP) technique that uses a series of thrombus extraction by withdrawing the stent retriever into the aspiration catheter and continuous aspiration from the aspiration catheter at the first attempt.

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Is Vertebral Column Resection Necessary in Correcting Severe and Rigid Thoracic Kyphoscoliosis? A Single-Institution Surgical Experience  Voir?

Three-column spinal osteotomies were developed to address severe and stiff kyphoscoliosis. However, the optimal choice of osteotomy in these patients is still unclear. This retrospective study aims to compare the outcomes and complications between grade 4 and grade 5 osteotomies in patients with severe and stiff thoracic kyphoscoliosis.

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Management of through-and-through penetrating skull injury: a railroad stake that transgressed the anterior skull base  Voir?

Penetrating injuries involving foreign objects that transgress the entirety of the human skull presents challenges in the management of vascular injuries, infectious risk, cerebrospinal fluid leak, and cosmetic repair. Ultimately, effective management of these injuries requires a multi-disciplinary team and judicious surgical planning. Here we present the management of a patient who suffered a penetrating injury from a railroad stake, with entry and exit points involving left and right anterior aspect of the temporal fossa, respectively.

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The Effects of Red Blood Cell Transfusion on Functional Outcome after Aneurysmal Subarachnoid Hemorrhage  Voir?

The optimal red blood cell transfusion (RBCT) trigger for patients with aneurysmal subarachnoid hemorrhage (SAH) is unknown. In patients with cerebral vasospasm, anemia may increase susceptibility to ischemic injury; conversely, RBCT may worsen outcome given known deleterious effects.
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Preoperative Prediction of the Necessity for Anterior Clinoidectomy During Microsurgical Clipping of Ruptured Posterior Communicating Artery Aneurysms  Voir?

Although most posterior communicating artery (PCoA) aneurysms can be clipped easily with excellent results, some require anterior clinoidectomy for safe and complete clipping.
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The Hypoglossal Nerve: Anatomical Study of Its Entire Course  Voir?

Only a few anatomic studies of the entire course of the hypoglossal nerve (cranial nerve XII) have been reported. We analyzed all relationships of the 12th nerve with surrounding structures from the brainstem to the tongue through a microscopic perspective. A comprehensive anatomically and clinically oriented classification of its different segments is proposed.

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Emergency Extracranial-Intracranial Bypass to Revascularize Salvageable Brain Tissue in Acute Ischemic Stroke Patients  Voir?

To present an algorithm based on clinical and radiologic factors, including magnetic resonance imaging (MRI) perfusion/diffusion mismatch (PDM), for the indication of urgent cerebral bypass in patients with acute ischemic stroke.
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"Spontaneous Fusion of S2/S3 Spondyloptosis in an Adult: A Case Report"  Voir?

Spondyloptosis is grade V on the Meyerding classification. Traumatic spondyloptosis can occur throughout the spinal column, particularly at junctional levels, and finding the ideal surgical strategy to address it remains a challenge for spinal surgeons. The sacrum is considered a united bone in adults and sacral inter-segmental spondyloptosis is extremely rare. Herein, we present a very unusual case of S2/S3 spondyloptosis in a 27-year-old female patient with spontaneous solid fusion and we discuss the relevant literature.

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Elevation of Proenkephalin 143–183 in Cerebrospinal Fluid in Moyamoya Disease  Voir?

In moyamoya disease (MMD), the causes of differences in clinical features between children and adults and of the dramatic temporal changes in moyamoya vessels are poorly understood. We previously discovered elevated levels of m/z 4588 and m/z 4473 peptides in cerebrospinal fluid (CSF) in patients with MMD. This study examined the amino acid sequences of these peptides and quantified in specimens.

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Pattern of Closure of Skull Base Synchondroses in Crouzon Syndrome  Voir?

The age of closure of skull base synchondroses has never been analyzed in a homogenous population of children with Crouzon syndrome.
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Syrinx to subarachnoid shunting for syringomyelia  Voir?

Surgery for syringomyelia generally aims to treat the underlying cause, if it is known. Optimal management is unclear for idiopathic syringomyelia, or where treatment of the putative cause has failed or is high risk. Syrinx to subarachnoid shunting is an option for these cases; a series is reported to assess the outcomes of this approach.

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Outcomes After Transcranial and Endoscopic Endonasal Approach for Tuberculum Meningiomas—A Retrospective Comparison  Voir?

Degree of resection and visual outcome are the main concerns in the surgical resection of tuberculum sellae meningioma (TSM). In addition to the transcranial approach (TCA), the endoscopic endonasal approach (EEA) has been used increasingly. However, the controversy regarding the optimal surgical approach is not clearly resolved.

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Analogous Three-Dimensional Constructive Interference in Steady State Sequences Enhance the Utility of Three-Dimensional Time of Flight Magnetic Resonance Angiography in Delineating Lenticulostriate Arteries in Insular Gliomas: Evidence from a Prospective Clinicoradiologic Analysis of 48 Patients  Voir?

Three-dimensional (3D) time of flight (TOF) imaging is the current gold standard for noninvasive, preoperative localization of lenticulostriate arteries (LSAs) in insular gliomas; however, the utility of this modality depends on tumor intensity.
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Predisposing Factors of Fracture Nonunion After Posterior C1 Lateral Mass Screws Combined with C2 Pedicle/Laminar Screw Fixation for Type II Odontoid Fracture  Voir?

The aim of this study was to explore the predisposing factors for fracture nonunion after a lateral screw was combined with C2 pedicle/laminar screw for a type II odontoid fracture and hopefully provide references in decision making and surgical planning for spinal surgeons.
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Endoscopic Transsphenoidal Surgery Outcomes in 331 Nonfunctioning Pituitary Adenoma Cases After a Single Surgeon Learning Curve  Voir?

The outcomes of recent endoscopic surgery of nonfunctioning pituitary adenomas (NFPAs) are controversial when compared with traditional microscopic surgery. We aimed to assess the outcomes of endoscopic transsphenoidal surgeries performed by 1 surgeon with 7 years of experience and elucidate the predictive factors for surgical outcomes for NFPAs.

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Cerebrospinal Fluid Leak at Percutaneous Exit of Ventricular Catheter as a Crucial Risk Factor for External Ventricular Drainage–Related Infection in Adult Neurosurgical Patients  Voir?

The placement of a ventricular catheter for temporary cerebrospinal fluid (CSF) diversion is associated with a considerable risk of CSF infection. The authors investigated the effect of a CSF leak on CSF-related infection and the predisposing factors for a CSF leak.
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Supraorbital Keyhole Approach to the Sella and Anterior Skull Base via a Forehead Wrinkle Incision  Voir?

To evaluate safety and effectiveness of supraorbital keyhole approach to the sella and anterior skull base via a forehead wrinkle incision.
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Identification of Driver Genes and Key Pathways of Glioblastoma Shows JNJ-7706621 as a Novel Antiglioblastoma Drug  Voir?

The aim of this study is to identify novel targets of diagnosis, therapy, and prognosis for glioblastoma, as well as to verify the therapeutic effect of JNJ-7706621 regarding glioblastoma.
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Individual Variability of the Human Cerebral Cortex Identified Using Intraoperative Mapping  Voir?

Intraoperative functional cortical mapping using direct electrical stimulation may show a wider individual variability than suggested by noninvasive imaging data of healthy subjects.
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Reappraisal of Neonatal Greenstick Skull Fractures Caused by Birth Injuries: Comparison of 3-Dimensional Reconstructed Computed Tomography and Simple Skull Radiographs  Voir?

The most common birth-associated head injuries during vaginal delivery are cephalhematomas and subgaleal hematomas. Cranial injuries are rarely encountered. The neonate cranium is soft and pliable, and greenstick skull fractures (GSFs) are expected to be more frequent than linear or depressed fractures, but they are extremely difficult to detect with simple skull radiography. As a result, no reports have been issued on this topic to date. Recent reports suggest that technological advances in 3-dimensional (3D) computed tomography (CT) have successfully enhanced the diagnostic accuracy for cranial fractures.

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Modular Classification of Endoscopic Endonasal Transsphenoidal Approaches to Sellar Region: Anatomic Quantitative Study  Voir?

Endoscopic visualization does not necessarily correspond to an adequate working space. The need for balancing invasiveness and adequacy of sellar tumor exposure has recently led to the description of multiple endoscopic endonasal transsphenoidal approaches. Comparative anatomic data on these variants are lacking.

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Comparison of Quality Metrics for Pediatric Shunt Surgery and Proposal of the Negative Shunt Revision Rate  Voir?

Shunt surgery is common in pediatric neurosurgery and is associated with relevant complication rates. We aimed to compare previously published metrics in a single data set and propose the Negative Shunt Revision Rate (NSRR), defined as proportion of shunt explorations revealing a properly working system, as a new quality metric.

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Surgery and Radiotherapy for Symptomatic Spinal Metastases Is More Cost Effective Than Radiotherapy Alone: A Cost Utility Analysis in a U.K. Spinal Center  Voir?

Surgery for symptomatic spinal metastases is effective at prolonging ambulation and life, but it can appear costly at first glance. We have studied the difference between the cost of surgery and reimbursement received, and the cost-effectiveness of surgery in a U.K. tertiary referral spinal center.
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Comparison of Chronic Dysphagia in Standalone versus Conventional Plate and Cage Fusion  Voir?

Standalone cages have gained popularity because of their ease of implantation, reduced operating time, and lower profile compared with traditional plate and cage systems. The aim of this study was to compare the risk of chronic dysphagia between those who undergwent anterior cervical discectomy and fusion (ACDF) with traditional plating techniques and those who underwent standalone procedures.

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Surgical management of giant intracranial meningioma: operative nuances, challenges and outcome  Voir?

The giant intracranial meningioma [GIM] constitutes a different spectrum of brain tumors which invade the vital neurovascular structures and makes the primary mode of treatment, surgery, a technically challenging one. The surgery of GIM is unique due to its large size, prominent vascularity, entangling and limited visualisation of various neurovascular structures and severe cerebral edema. The study reports the authors surgical experience of 80 GIM cases, the operative challenges and surgical outcome.

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The endoscopic buccal fat pad flap for closure of skull base defects: a report of five cases  Voir?

To demonstrate the clinical utility of the buccal fat pad to close a variety of skull base defects.
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Contact Aspiration with the New ARC Catheter for Thrombectomy of Acute Ischemic Stroke: Single-Center Results  Voir?

Contact aspiration has gained growing acceptance in endovascular stroke therapy. The safety and efficacy data of the novel ARC catheter (Medtronic, Irvine, California, USA) used for intracranial thrombectomy have been poorly evaluated thus far. We report our preliminary results with the ARC with regard to angiographic reperfusion, duration of thrombectomy, safety, and clinical outcome at 90 days.

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Early Hemodynamic Changes Based on Initial Color-Coding Angiography as a Predictor for Developing Subsequent Symptomatic Vasospasm After Aneurysmal Subarachnoid Hemorrhage  Voir?

Prediction of vasospasm after aneurysmal subarachnoid hemorrhage (aSAH) remains imperfect and currently relies on clinical and radiographic characteristics. Whether early hemodynamic changes may refine risk stratification for delayed vasospasm (DV) after aSAH was analyzed.
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World Health Organization Grade II Meningiomas: The Role of Adjuvant/Salvage Gamma Knife Surgery After Initial Surgery and Prognostic Factor Assessment  Voir?

This study was performed to evaluate the efficiency of Gamma Knife surgery (GKS) on reducing recurrence of World Health Organization (WHO) grade II meningiomas after surgery and to define the risk factors associated with tumor recurrence/progression and patient's death.
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Factors Associated with 90-Day Outcomes of Patients with Acute Posterior Circulation Stroke Treated By Mechanical Thrombectomy  Voir?

Early recanalization of acute posterior circulation stroke caused by large intracranial vessel occlusion by mechanical thrombectomy with stent retrievers may improve the outcome of patients. However, evidence of patient selection is still lacking. This study investigated the prognostic factors of acute posterior circulation stroke caused by large intracranial arterial occlusion when treated with stent-retriever thrombectomy.

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Post Natal Management of Myelomeningocele: Outcome with a Multidisciplinary Team Experience  Voir?

Myelomeningocele (MMC) is a complex neural tube defect. Few studies report the results of modern post-natal management. The goal of this study was to report the long term outcome of a multidisciplinary approach of MMC patients.
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Physiologic Growth Hormone–Replacement Therapy and Craniopharyngioma Recurrence in Pediatric Patients: A Meta-Analysis  Voir?

A systematic review and meta-analysis were conducted to examine the effect of growth hormone–replacement therapy (GHRT) on the recurrence of craniopharyngioma in children.
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Training of Intra-Axial Brain Tumor Resection Using a Self-Made Simple Device with Agar and Gelatin  Voir?

Self-made devices composed of agar and gelatin gel were used for resident training in intra-axial brain tumor resection. The mixture gel of agar and gelatin is retractable and can be suctioned. Hardness of the gel depends on the concentration of the solution. Therefore, by changing the concentration, it is easy to make gels of various hardness.

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Intracranial Meningioma in Patients Age <35 Years: Evolution of the Disease in the Era of Human Immunodeficiency Virus Infection  Voir?

Intracranial meningiomas are most common among patients in their fifth to seventh decade of life and rare in children and young adults. They constitute 1.5% of all neoplasms in patients age <20 years, but account for 13.5% of all neoplasms in patients age 20–34 years. They are often associated with hereditary or familial syndromes in children and young adults, and tend to be of high grade. Here we describe the histopathological subtypes of intracranial meningioma between human immunodeficiency virus 1 (HIV-1)-seropositive patients and the general population with intracranial meningiomas 35 years old and younger.

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Contralateral Approach to Middle Cerebral Artery Aneurysms: An Anatomical-Clinical Analysis to Improve Patient Selection  Voir?

A contralateral approach to aneurysm clipping in cases of bilateral middle cerebral artery (MCA) aneurysms reduces surgical time and cost. However, there is a lack of evidence for objective patient selection. In this study, we assessed the change in surgical freedom along the contralateral MCA to provide objective evidence for patient selection.

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Subtemporal Approach for Gross Total Resection of Retrochiasmatic Craniopharyngiomas: Our Experience on 30 Cases  Voir?

Surgical treatment of retrochiasmatic craniopharyngiomas is associated with higher rates of complications, mortality, failure of complete removal, and recurrence compared with craniopharyngiomas located elsewhere. These tumors lie behind the optic chiasm and when large can extend upward into the third ventricle and downward along the brain stem, making their adequate exposure challenging. Most of the proposed techniques either use a translamina terminalis route or require wide bony exposures. In this study, we assessed the feasibility of a subtemporal approach for achieving gross total resection of retrochiasmatic craniopharyngiomas.

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Quality and Quantity of Memories in Patients Who Undergo Awake Brain Tumor Resection  Voir?

Awake craniotomy is performed with increasing frequency for brain tumor surgery in eloquent areas; however, little is known about patients' memories of this procedure. Here we retrospectively analyzed the quality and quantity of memories in a series of patients treated following a standardized protocol.

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Acute Response of Neurons: An Early Event of Neuronal Cell Death After Facial Nerve Injury  Voir?

To research the early acute response events of facial nerve injury.
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Effect of Single-Level Transforaminal Lumbar Interbody Fusion on Segmental and Overall Lumbar Lordosis in Patients with Lumbar Degenerative Disease  Voir?

To investigate the ability of transforaminal lumbar interbody fusion (TLIF) to improve lumbar lordosis (LL).
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Endovascular Treatment of Ruptured Vertebrobasilar Dissecting Aneurysms Using Flow Diversion Embolization Devices: Single-Institution Experience  Voir?

Treatment of ruptured posterior circulation dissecting aneurysms is technically challenging with potentially high morbidity and mortality. We sought to assess the safety and feasibility of using a flow-diversion device (FDD) and a specific acute antiplatelet aggregation protocol in the management of ruptured dissecting aneurysms.

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Intracranial Hemorrhage in Patients with Durable Mechanical Circulatory Support Devices: Institutional Review and Proposed Treatment Algorithm  Voir?

Spontaneous intracranial hemorrhage (ICH) is frequently managed in neurosurgery. Patients with durable mechanical circulatory support devices, including total artificial heart (TAH) and left ventricular assist device (LVAD), are often encountered in the setting of ICH. Although durable mechanical circulatory support devices have improved survival and quality of life for patients with advanced heart failure, ICH is one of the most feared complications following LVAD and TAH implantation. Owing to anticoagulation and clinically relevant acquired coagulopathies, ICH should be treated promptly by neurosurgeons and cardiac critical care providers.

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Machine Learning and Neurosurgical Outcome Prediction: A Systematic Review  Voir?

Accurate measurement of surgical outcomes is highly desirable to optimize surgical decision-making. An important element of surgical decision making is identification of the patient cohort that will benefit from surgery before the intervention. Machine learning (ML) enables computers to learn from previous data to make accurate predictions on new data. In this systematic review, we evaluate the potential of ML for neurosurgical outcome prediction.

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Anterior Cervical Discectomy with Instrumented Allograft Fusion: Lordosis Restoration and Comparison of Functional Outcomes among Patients of Different Age Groups  Voir?

To investigate clinical parameters of anterior cervical discectomy and fusion (ACDF) treatment and outcomes using osseous allografts in different age groups, study the postoperative results of restoration of lordosis, and evaluate the utility of bone allografts for ACDF, including graft subsidence.
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Internal Carotid Artery and Its Relationship with Structures in Sellar Region: Anatomy Study and Its Clinical Applications  Voir?

Complications of the ICA in surgeries are rare but severe. This study aims to locate the ICA with 5 stationary bony structures in the sellar region: the anterior clinoid process (ACP), the tuberculum sellae, the bottom of the hypophyseal fossa, the posterior edge of the hypophyseal fossa and the post clinoid process and do measurements to determine their anatomic relationship with the ICA.

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Analysis of Survival Prognosis for Children with Symptomatic Optic Pathway Gliomas Who Received Surgery  Voir?

The feasibility and prognosis of surgical treatment for children with optic pathway gliomas (OPGs) is controversial. Therefore this study attempted to evaluate the effects of surgery and discuss prognostic factors related to the survival of children with symptomatic OPGs.
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Application of Gelatin Sponge Impregnated with a Mixture of 3 Drugs to Intraoperative Nerve Root Block Combined with Robot-Assisted Minimally Invasive Transforaminal Lumbar Interbody Fusion Surgery in the Treatment of Adult Degenerative Scoliosis: A Clinical Observation Including 96 Patients  Voir?

Application of nerve root block is mainly for diagnosis with less application in intraoperative treatment. The aim of this study was to observe clinical and imaging outcomes of application of gelatin sponge impregnated with a mixture of 3 drugs to intraoperative nerve root block combined with robot-assisted minimally invasive transforaminal lumbar interbody fusion surgery in to treat adult degenerative lumbar scoliosis.

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Intradural Spinal Tumors—Review of Postoperative Outcomes Comparing Intramedullary and Extramedullary Tumors from a Single Institution's Experience  Voir?

Intradural spinal tumors are rare and can be classified into extramedullary or intramedullary. They commonly present with symptoms such as intractable back pain or neurologic deficits. We retrospectively reviewed 91 cases of intradural spinal tumors that underwent surgery in our institution from 2011 to 2016 and assessed their clinical outcomes. The majority of intradural tumors were extramedullary (89%), and the most common pathology was schwannoma (38.5%) followed by meningioma (29.7%). Comparing extramedullary versus intramedullary tumors, both groups experienced similar improvement in neurologic status post surgery (92.6% vs.

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Alarming Internal Carotid Artery Aneurysm Eroding the Sphenoid Sinus  Voir?

In rare instances, extradural internal carotid artery aneurysms can present with massive epistaxis, which is often a fatal event. We present the case of a young female with an aneurysm eroding through the sphenoid sinus and whose timely diagnosis resulted in treatment of the aneurysm with coil embolization and satisfactory outcome.

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Benchmarking Distance Control and Virtual Drilling for Lateral Skull Base Surgery  Voir?

Novel audiovisual feedback methods were developed to improve image guidance during skull base surgery by providing audiovisual warnings when the drill tip enters a protective perimeter set at a distance around anatomic structures (“distance control”) and visualizing bone drilling (“virtual drilling”).

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Validation of a Predictive Scoring System for Ventriculoperitoneal Shunt Insertion After Aneurysmal Subarachnoid Hemorrhage  Voir?

Hydrocephalus is a frequently encountered complication in the context of aneurysmal subarachnoid hemorrhage (aSAH). Here, we performed an external validation of the recently proposed postsubarachnoid shunt scoring (PS3) system, which aims to stratify patients presenting with aSAH based on their relative risk of requiring ventriculoperitoneal (VP) shunt insertion.

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Cerebral Aneurysm Associated with an Arachnoid Cyst: 3 Case Reports and a Systematic Review of the Literature  Voir?

Arachnoid cysts and intracranial aneurysms are not rare, but it is unusual for an aneurysm to be associated with an arachnoid cyst. The objective of this study was to reveal the association between arachnoid cysts and intracranial aneurysms.
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An improved microvascular decompression in treating trigeminal neuralgia: application of nest-shaped Teflon fibers  Voir?

The aim of this study was to develop an improved Microvascular decompression (MVD) surgery using nest-shaped Teflon fibers. Eighteen consecutive trigeminal neuralgia (TN) patients who underwent MVD using nest-shaped Teflon fibers between January 2012 and December 2013 were included in this investigation. During the surgery, the nest shape of Teflon was formed by gently pushing Teflon prosthesis at the center position toward the periphery. Immediate postoperative outcome was evaluated using numerical rating scale (NRS) score, then patients were followed up for recurrence.

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Comparative Study of Cortical Bone Trajectory-Pedicle Screw (Cortical Screw) Versus Conventional Pedicle Screw in Single-Level Posterior Lumbar Interbody Fusion: A 2-Year Post Hoc Analysis from Prospectively Randomized Data  Voir?

The aim of this study was to report 2-year follow-up outcomes of posterior lumbar interbody fusion (PLIF) with cortical bone trajectory-pedicle screw (CS), in terms of fusion rates, clinical outcomes, surgical outcomes, and complications, and to compare these outcomes with outcomes for PLIF with conventional pedicle screw (PS).

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Endovascular Treatment of Unruptured Intracranial Aneurysms by the Woven EndoBridge Device (WEB): Are There Any Aspects Influencing Aneurysm Occlusion?  Voir?

The experience with Woven EndoBridge (WEB) device is still limited. The aim of this study is to discuss the efficacy of this new device, focusing on any anatomical and procedural factors influencing aneurysm occlusion.
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The Long and Winding Road: Thoracic Myelopathy Associated With Occipitocervical Dural Arteriovenous Fistula  Voir?

Spinal dural arteriovenous fistulas (DAVFs) have diverse presentations. Magnetic resonance imaging (MRI) reveals spinal cord swelling in only 45% to 74% of cases. We present an unusual case of a 57-year old man with a craniocervical junction DAVF in which the edema appeared in the thoracolumbar region, skipping the cervical spinal cord.

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http://www.worldneurosurgery.org/article/S1878-8750(17)31474-2/fulltext?rss=yes

In this 2-volume set, editors Dr. Edward Benzel and Dr. Michael Steinmetz have compiled an exceptional text comprising nearly every aspect of spine surgery. Among more than 200 chapters, 26 new chapters are dedicated to hot topics within the field. Video content is also provided in 18 intraoperative videos illustrating multiple skills and techniques used in spine surgery.

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Computed Tomography Angiography Spot Sign as an Indicator for Ultra-Early Stereotactic Aspiration of Intracerebral Hemorrhage  Voir?

Ultra-early surgical clot removal relieves mechanical compression on adjacent normal brain tissue and limits the toxic effects of a hematoma, which might improve the outcomes in patients with intracerebral hemorrhage (ICH); however, hematoma expansion frequently occurs within 20 hours after the ictus, and this limits the use of ultra-early surgery. Computed tomography angiography spot sign was recently validated as an important predictor of hematoma expansion in patients with ICH.

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Intracranial Aneurysms in Adult Moyamoya Disease  Voir?

The prevalence of aneurysm formation in adults with moyamoya disease (MMD) is approximately 14%, and it represents a major potential hemorrhagic risk. We aimed to study the characteristics of intracranial aneurysms occurring in patients with MMD. We retrospectively reviewed our 10-year experience of patients with intracranial aneurysms and a diagnosis of MMD at our hospital.

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The Effect of July Admission on Inpatient Morbidity, Mortality, and Discharge Disposition After Endovascular Coiling in Subarachnoid Hemorrhage  Voir?

To investigate effect of July admission on short-term outcome after endovascular coiling of patients with subarachnoid hemorrhage (SAH) owing to ruptured aneurysms.
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Transoral Decompression and Stabilization of the Upper Cervical Segments of the Spine Using Custom-Made Implants in Various Pathologic Conditions of the Craniovertebral Junction  Voir?

Surgical treatment of patients with atlantoaxial instability caused by pathologic changes of the skull base and craniovertebral junction combined with anterior compression of the brain stem is still associated with substantial technical difficulties and remains a matter of debate. Currently, anterior stabilization of the atlantoaxial junction is a promising approach that allows for the resection of the pathologic lesion of the skull base and craniovertebral junction with subsequent stabilization of C1–C2 or C1–C3 in 1 stage.

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Effect of Interlaminar Epidural Steroid Injection in Patients with Central Cervical Spinal Stenosis  Voir?

To investigate the effect of interlaminar epidural steroid injection (ESI) for management of central cervical spinal stenosis–induced posterior neck pain.
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Two-Year Results of the Prospective Spine Treatment Outcomes Study: Analysis of Postoperative Clinical Outcomes Between Patients with and without a History of Previous Cervical Spine Surgery  Voir?

History of previous cervical spine surgery is a frequently cited cause of worse outcomes after cervical spine surgery. The purpose of this study was to determine any differences in clinical outcomes after cervical spine surgery between patients with and without a history of previous cervical spine surgery.

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Low-Pressure Hydrocephalus: A Case Report and Review of the Literature  Voir?

The entity of low-pressure hydrocephalus remains poorly understood and thoroughly debated. Symptomatic improvement accompanied by decrease in ventricular size after prolonged subatmospheric drainage has been well documented, and this method has been considered the criterion standard of management. Few studies have examined alternative treatment options, either to avoid the risks associated with prolonged external ventricular drainage or because of the failure of traditional methods.

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Arachnoid Cyst–Associated Chronic Subdural Hematoma: Report of 14 Cases and a Systematic Literature Review  Voir?

Arachnoid cyst (AC)-associated chronic subdural hematoma (CSDH) differs significantly from its counterparts without AC in epidemiologic, demographic, and clinical characteristics, as well as in management and prognosis. This study was conducted to further examine the epidemiologic, demographic, and clinical characteristics; diagnosis; treatment; and prognosis of AC-associated CSDH.

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Microscopic Minimally Invasive Keyhole Technique for Surgical Resection of Spinal Dumbbell Tumors  Voir?

Multiple surgical modalities have been developedl and applied for surgical excision of spinal dumbbell tumors. The microscopic minimally invasive keyhole technique has not yet been well characterized for this purpose. We report our experience with 1-stage surgical resection of both intraforaminal and extraforaminal/paraspinal components of spinal dumbbell tumors using the microsurgical keyhole technique.

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Effectiveness of the 3D Monitor System for Medical Education During Neurosurgical Operation  Voir?

Three-dimensional (3D) graphics are used in the medical field, especially during surgery. Although 3D monitoring is useful for medical education, its effectiveness needs to be objectively evaluated. The aim of this study was to investigate the efficacy of 3D monitoring in the surgical education of medical students.

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Comparison of Recanalization and In-Stent Stenosis Between the Low-Profile Visualized Intraluminal Support Stent and Enterprise Stent-Assisted Coiling for 254 Intracranial Aneurysms  Voir?

To compare the rates of recanalization and in-stent stenosis between the Enterprise (EP) and low-profile visualized intraluminal support (LVIS) stent deployments for intracranial aneurysms (IAs), and the factors associated therein.
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Clinical Features, Treatment, and Long-term Outcomes of Central Neurocytoma: A 20-Year Experience at a Single Center  Voir?

Central neurocytoma (CN) is a rare central nervous system tumor the optimal management strategy of which remains controversial because of their rarity. Detailed information on CN is necessary to establish optimal management strategies. The purpose of this study was to show the clinical features, treatments, and long-term clinical outcomes of CN.

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Early Transient Mild Hypothermia Attenuates Neurologic Deficits and Brain Damage After Experimental Subarachnoid Hemorrhage in Rats  Voir?

Metabolic exhaustion in ischemic tissue is the basis for a detrimental cascade of cell damage. In the acute stage of subarachnoid hemorrhage (SAH), a sequence of global and focal ischemia occurs, threatening brain tissue to undergo ischemic damage. This study was conducted to investigate whether early therapy with moderate hypothermia can offer neuroprotection after experimental SAH.

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Minimally Invasive Excision of Thoracic Arachnoid Web  Voir?

Arachnoid webs are rare intradural lesions that can cause direct spinal cord compression or alteration of the cerebrospinal fluid flow with syringomyelia. Surgery has been historically performed through wide-open laminectomies. The aim of this study is to prove the feasibility of minimally invasive techniques for the excision of arachnoid webs.

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Diagnosis and Outcomes of 341 Patients with Cushing's Disease Following Transsphenoid Surgery: A Single-Center Experience  Voir?

Transsphenoid surgery (TSS) is a standard treatment modality for Cushing's disease (CD). However, postoperative remission and recurrence rates vary among studies. Here we analyze the diagnosis and outcomes of 341 patients with a preoperative diagnosis of CD undergoing TSS in a single center over a 3-year period.

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Prognostication of Survival Outcomes in Patients Diagnosed with Glioblastoma  Voir?

Glioblastoma multiforme (GBM) is an aggressive primary brain tumor with dismal survival. This study aims to examine the prognostic value of primary tumor sites and race on survival outcomes.
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Histopathologic Features in Relation to Pretreatment Tumor Growth in Patients with Glioblastoma  Voir?

Rapid growth is a well-known property of glioblastoma (GBM); however, growth rates vary among patients. Mechanisms behind such variation have not been widely studied in human patients. We sought to investigate relationships between histopathologic features and tumor growth estimated from pretreatment magnetic resonance imaging scans.

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Intraoperative Magnetic-Resonance Tomography and Neuronavigation During Resection of Focal Cortical Dysplasia Type II in Adult Epilepsy Surgery Offers Better Seizure Outcomes  Voir?

Focal cortical dysplasia (FCD) is one important cause of drug-resistant epilepsy potentially curable by epilepsy surgery. We investigated the options of using neuronavigation and intraoperative magnetic-resonance tomographical imaging (MRI) to avoid residual epileptogenic tissue during resection of patients with FCD II to improve seizure outcome.

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Spinal Metastasis of Unknown Primary Accompanied by Neurologic Deficit or Vertebral Instability  Voir?

Spinal bone metastases are common. They are mostly localized to the lumbar, thoracic, and cervical spine. The most common primaries to result in spinal metastases include lung, breast, and prostate carcinomas in adults as opposed to leukemia, Ewing sarcoma, rhabdomyosarcoma, and neuroblastoma in children. In patients diagnosed with cancer, bone metastases are found in 40% and spinal metastases in 10%. In this study, we reviewed 25 patients diagnosed with a spinal metastasis of unknown primary who presented with low back pain or acute-onset neurologic deficits and underwent operative treatment.

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Acute Bilateral Foot Drop as Presenting Symptom of Hemorrhagic Synovial Cyst of Lumbar Spine  Voir?

Acute bilateral foot drop is a rare clinical presentation.
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Effectiveness and Limitations of Intraoperative Monitoring with Combined Motor and Somatosensory Evoked Potentials During Surgical Clipping of Unruptured Intracranial Aneurysms  Voir?

Postoperative neurologic deficits are one of the devastating complications that can result from surgical clipping of unruptured intracranial aneurysms. Intraoperative monitoring (IOM) of motor and somatosensory evoked potentials (EPs) has been used to reduce neurologic sequelae. We evaluated the effectiveness and limitations of IOM in prevention of surgical complications during aneurysm clipping.

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Occipital Intraosseous Hemangioma over Torcula: Unusual Presentation with Raised Intracranial Pressure  Voir?

Hemangiomas of the bone are benign, uncommon, slow-growing lesions accounting for <1.0% of all bony neoplasms. Intraosseous occipital hemangiomas are rare, and occipital hemangiomas presenting with features of raised intracranial tension are, with only 2 cases reported to date.
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Anatomic Predictors of Unruptured Anterior Communicating Artery Aneurysm Growth  Voir?

Anatomic variations of the anterior communicating artery (ACOM) complex have been shown to influence ACOM aneurysm morphology. It is not known whether these variations predispose unruptured ACOM aneurysms to grow over time.
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Revision Rate of Misplaced Pedicle Screws of the Thoracolumbar Spine–Comparison of Three-Dimensional Fluoroscopy Navigation with Freehand Placement: A Systematic Analysis and Review of the Literature  Voir?

Recent studies have shown higher accuracy rates of image-guided pedicle screw placement compared to freehand (FH) placement. However, data focusing on the impact of spinal navigation on the rate of revision surgeries caused by misplaced pedicle screws (PS) are scarce.
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Clinical Outcomes with Transcranial Resection of the Tuberculum Sellae Meningioma  Voir?

The tuberculum sellae is a relatively common location for meningiomas. We assessed our experience with the use of transcranial resection, which, although criticized for its more invasive nature compared with endonasal approaches, may be the ideal approach in selected patients with tuberculum sellae meningiomas (TSMs).

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Impact of Symptomatic Metastatic Spinal Cord Compression on Survival of Patients with Non-Small-Cell Lung Cancer  Voir?

Non-small-cell lung cancer (NSCLC) is one of the most common primary tumor sites among patients with metastatic spinal cord compression (MSCC). This disorder is related to neurologic dysfunction and can reduce the quality of life, but the association between MSCC and death is unclear. The aim of this study was to analyze the impact of the occurrence of symptomatic MSCC on overall survival of patients with NSCLC.

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Surgical Treatment of Mirror Middle Cerebral Artery Aneurysms: Bilateral and Unilateral Approach  Voir?

Currently, the optimal surgical approach for bilateral aneurysms remains controversial. Alternative interventional methods, such as unilateral or bilateral approaches, have been used during a single session or 2 different sessions. The unilateral approach can be used successfully to treat contralateral aneurysms that develop in a paramedian location. However, such an approach is more difficult for treating contralateral aneurysms in more distant locations. The unilateral approach can decrease complication rates, operation time, and length of hospital stay.

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Schwannomas of the Frontal Sinus: Cases and Review of the Literature  Voir?

Although schwannomas are commonly found in the head and neck region, sinonasal tract involvement is extremely rare, estimated as <4%. The presence of these lesions in the frontal sinus is even less common.
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Giant Cell Ependymoma of Lateral Ventricle: Case Report, Literature Review, and Analysis of Prognostic Factors and Genetic Profile  Voir?

Giant cell ependymoma (GCE) is a rare primary central nervous system neoplasm. We report a case of GCE arising in the lateral ventricle.
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Occipital Microarteriovenous Malformation Resection, Strategy, and Nuances  Voir?

We describe a patient who presented with superior quadrianopsia due to an occipital micro AVM that bled into the optic radiation. Onyx embolization was attempted. However, early follow-up angiogram revealed recanalization and recurrence of the AVM. He was then taken to the hybrid operative room, where a complete resection was achieved confirmed by intraoperative angiogram. He made a complete recovery with no new neurologic deficit and stable visual field deficit. This case demonstrates treatment strategy, surgical planning, and technical nuances in microsurgical resection of micro AVMs located in an eloquent area.

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Rotational Vertebral Artery Dissection Secondary to Anomalous Entrance into Transverse Foramen  Voir?

Rotational vertebral artery occlusion is a rare syndrome characterized by vertebrobasilar insufficiency secondary to position-dependent occlusion of the vertebral artery. Most cases reported in the literature have been attributed to osteophytic compression, either from the occipital condyle or within the transverse foramen. However, vertebral artery dissection secondary to motion in the setting of anomalous anatomy has not been reported.

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Epidemiology, Management, and Functional Outcomes of Traumatic Brain Injury in Sub-Saharan Africa  Voir?

Trauma accounts for 4.7 million deaths each year, with an estimated 90% of these occurring in low- and middle-income countries (LMICs). Approximately half of trauma-related deaths are caused by central nervous system injury. Because a thorough understanding of traumatic brain injury (TBI) in LMICs is essential to mitigate TBI-related mortality, we established a clinical and radiographic database to characterize TBI in our low-income setting.

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Impact of Hospital Caseload and Elective Admission on Outcomes After Extracranial-Intracranial Bypass Surgery  Voir?

Limited information exists evaluating the impact of hospital caseload and elective admission on outcomes after patients have undergone extracranial-intracranial (ECIC) bypass surgery. Using the Nationwide Inpatient Sample (NIS) for 2001–2014, we evaluated the impact of hospital caseload and elective admission on outcomes after bypass.

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Long-Term Efficacy of Nerve Combing for Patients with Trigeminal Neuralgia and Failed Prior Microvascular Decompression  Voir?

Microvascular decompression (MVD) of the trigeminal nerve is the most effective treatment for trigeminal neuralgia (TN). However, many patients respond poorly to initial MVD. For these patients, redo MVD is commonly done. There has been no research regarding the effectiveness of nerve combing (NC) plus MVD in patients with TN and failed prior MVD. We compared the clinical outcome of NC plus MVD and simple redo MVD in patients with TN and failed prior MVD.

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Management of Blood Blister–Like Aneurysms of the Internal Carotid Artery: Lessons Learned from Direct Clipping in 22 Cases  Voir?

To present a case series of blood blister–like aneurysms (BBAs) of the internal carotid artery (ICA) and an assessment of diagnosis and treatment options, attempting to identify surgical or endovascular management of BBAs with a low complication rate and a functional outcome.
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Top 100 Most-Cited Articles on Spontaneous Intracerebral Hemorrhage: A Bibliometric Analysis  Voir?

A bibliometric uses the citation count of an article to determine its impact on the clinical world. There is a paucity of literature concerning top article citations on spontaneous intracerebral hemorrhage (ICH). The main objective of this investigation was to bridge this gap and to provide understanding of the trends on the most influential articles written on this subject.

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Severe Cerebral Complications Secondary to Perforation Injury of the Anterior Skull Base During Sinonasal Surgery: An Underappreciated Problem?  Voir?

Functional endonasal sinus surgery (FESS) is widely practiced and is considered a generally safe procedure. Skull base injuries occur in <1% of procedures and are typically associated with cerebrospinal fluid leaks. Rarely, skull base injuries might result in cerebral lesions. Here we present a series of 4 patients with iatrogenic perforating injuries of the anterior skull base and cerebral lesions after routine FESS.

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Prognostic Value of Early S100 Calcium Binding Protein B and Neuron-Specific Enolase in Patients with Poor-Grade Aneurysmal Subarachnoid Hemorrhage: A Pilot Study  Voir?

This prospective study was undertaken to investigate the value of early S100 calcium binding protein B (S100B) and neuron-specific enolase (NSE) in prognosticating outcome in patients with poor-grade aneurysmal subarachnoid hemorrhage and to develop a statistical model and cutoff values for clinical practice.

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Failure Patterns in Standalone Anterior Cervical Discectomy and Fusion Implants  Voir?

Anterior cervical discectomy and fusion is commonly performed using an allograft or autograft implant and anterior screw-supported plate. There has been an increase in the use of standalone cage devices due to ease of use and studies suggesting a lower rate of acute postoperative dysphagia. We review our experience with standalone cage devices and identify risk factors, patterns of failure, and revision surgery approaches.

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First Report of Renal Cell Carcinoma Metastasizing to the Clivus in a Pediatric Patient  Voir?

The clivus is a rare site of tumor occurrence in general, and metastases to this site are especially rare. Renal cell carcinoma is an uncommon entity in the pediatric population. Although not infrequent in adults, when it does occur, metastases to the clivus are extremely uncommon, only having been reported 3 times in the literature. All of these cases involved adults in their sixth decade.

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Integration of Functional Magnetic Resonance Imaging and Magnetoencephalography Functional Maps Into a CyberKnife Planning System: Feasibility Study for Motor Activity Localization and Dose Planning  Voir?

Magnetoencephalography (MEG) and functional magnetic resonance imaging (fMRI) provide noninvasive localization of eloquent brain areas for presurgical planning. The aim of this study is the integration of MEG and fMRI maps into a CyberKnife (CK) system to optimize dose planning.
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Ganglioglioma Progression to Combined Anaplastic Ganglioglioma and Anaplastic Pleomorphic Xanthoastrocytoma. Case Report and Literature Review  Voir?

Composite ganglioma and pleomorphic xanthoastrocytoma with anaplastic features in both components is an extremely rare glioneuronal tumor. Five cases of anaplastic progression in the glioma component have been reported. These tumors generally affect young patients who have brain tumor-related epilepsy, which are usually located in the temporal lobe or in the cerebellum and may have associated leptomeningeal spreading. Its current optimal treatment consists of maximal safe surgical resection and adjuvant chemoradiotherapy.

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Lumbar Spine Infection by Granulicatella and Abiotrophia Species  Voir?

The Granulicatella and Abiotrophia species are streptococci and natural inhabitants of the oral and urogenital flora. They are uncommonly associated with human pathology, although they can cause septicemia, endocarditis, or bacteremia. These microorganisms are difficult to culture and identify due to particular microenvironment requirements. Rarely, presentation is osteomyelitis or infections of the spine.

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Clinical Value of Multiparametric Whole-Body Magnetic Resonance Imaging over Whole-Spine Magnetic Resonance Imaging in Patients with Neurofibromatosis Type I  Voir?

To determine the clinical value of multiparametric whole-body (WBMRI) over whole-spine magnetic resonance imaging (WSMRI) in patients with neurofibromatosis type 1 (NF1).
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Comparison of 2 Operative Methods for Treating Laterocollis and Torticollis Subtypes of Spasmodic Torticollis: Follow-Up of 121 Cases  Voir?

The aim of this study was to compare the effects and complications of microvascular decompression (MVD) and neurectomy of spinal accessory nerve in the treatment of laterocollis and torticollis subtypes spasmodic torticollis (ST).
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Usefulness of Reintervention in Recurrent Glioblastoma: An Indispensable Weapon for Increasing Survival  Voir?

Glioblastoma is the most frequent primary brain tumor and despite of complete treatment survival is still poor. The aim of this study is to define the utility of reoperation for improving survival in patients with recurrent glioblastoma, and determine other prognostic factors associated with longer survival.

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Long-Term Patency of Posterior Auricular Artery—Middle Cerebral Artery Bypass for Adult-Onset Moyamoya Disease: Case Report and Review of Literature  Voir?

Direct extracranial-intracranial (EC-IC) bypass is one of the fundamental techniques to prevent recurrent stroke in patients with adult-onset ischemic moyamoya disease. When the standard superficial temporal artery (STA) cannot be used for a graft, the posterior auricular artery (PAA) can be a potential surrogate graft.

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Chronic Subdural Hematoma: A Historical and Clinical Perspective  Voir?

This review aims to highlight the clinical complexity of chronic subdural hematoma (cSDH) while presenting a brief historical discussion of cSDH.
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Chronic Subdural Hematoma: A Perspective on Subdural Membranes and Dementia  Voir?

To review the complex pathogenesis of the subdural membrane and the link between head trauma, dementia, and dural lymphatics.
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Fluorescein-Guided Resection of Intramedullary Spinal Cord Tumors: Results from a Preliminary, Multicentric, Retrospective Study  Voir?

Intramedullary spinal cord tumors (IMSCTs) are rare, heterogenous lesions that are usually enhanced on preoperative magnetic resonance imaging (MRI) because of a damaged blood-brain barrier. Sodium fluorescein is a dye that accumulates in areas of the central nervous system with a damaged BBB. Given the pattern of MRI contrast enhancement of the majority of IMSCTs, the use of this fluorescent tracer could improve tumor visualization and quality of resection. In this article, we present the first experience with the application of fluorescein-guided technique for surgical removal of IMSCTs.

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Results of Conservative Follow-up or Surgical Treatment of Moyamoya Patients Who Present without Hemorrhage, Transient Ischemic Attack, or Stroke  Voir?

The epidemiology of asymptomatic moyamoya disease (MMD) is still unclear, and the best management remains controversial. The aim of this study is to evaluate the prognosis of these patients with different management, conservative follow-up, or surgical treatment.
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Stereotactic Radiosurgery for Type 1 versus Type 2 Trigeminal Neuralgias  Voir?

It remains unclear whether stereotactic radiosurgery (SRS) offers the same benefit for patients with type 2 trigeminal neuralgia (TN2) as for those with type 1 trigeminal neuralgia (TN1). The objective of this study is to compare the outcomes of patients with TN1 and TN2 after SRS.
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Characteristics of Blood Blister-Like Aneurysms with a Saccular-Shape Appearance  Voir?

Blood blister-like aneurysms (BBAs) are a subgroup of aneurysms located on nonbranching sites of the internal carotid artery (ICA) and characterized by small size, a fragile wall, and a poorly defined broad-based neck. Both direct surgery and endovascular treatment for BBAs are often challenging. Some of the BBAs have been reported to look like true saccular aneurysms, and the misdiagnosis of BBA might result in catastrophic outcomes. The purpose of this study is to clarify the clinical and intraoperative findings of saccular BBAs.

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Hearing Outcome Following Microvascular Decompression for Hemifacial Spasm: Series of 1434 Cases  Voir?

Although hearing impairment after microvasuclar decompression (MVD) for hemifacial spasm (HFS) is not common, its occurrence could detrimentally affect the patient's surgical outcome. The object of this study is to address the optimal approaches for reducing postoperative hearing problems after MVD for HFS.

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Impact of Active Leisure (Noncompetitive) Contact Sports Activities on the Space Available for the Cord of the Subaxial Cervical Spine of Asymptomatic Adults  Voir?

Leisure sports activities are assumed to be safe. It is however possible that participation in contact sports as leisure activity may also affect the space available for the cervical cord (SAC). The objective of this study is to compare the SAC of asymptomatic young adults involved in active leisure contact sports with matched controls that do not participate in contact sports.

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Steinmann Pins for C1 Lateral Mass Screw Placement During Atlantoaxial Stabilization  Voir?

The authors describe a modified technique for placement of the C1 lateral mass screw using a Steinmann pin as a guide. This technique minimizes dissection and provides atlantoaxial stabilization during arthrodesis.
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C1-C2 Pedicle Screw Fixation for Atlantoaxial Dislocation in Pediatric Patients Younger than 5 Years: A Case Series of 15 Patients  Voir?

C1-C2 pedicle screw fixation has become popular for providing excellent bony purchase and avoiding neurovascular complications. However, it may be technically challenging in children. The objective of this study is to investigate the safety and efficacy of C1-C2 pedicle screw fixation for atlantoaxial dislocation (AAD) in pediatric patients younger than 5 years and to evaluate the preliminary clinical and radiographic results.

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The Safety of Irreversible Electroporation on Nerves Adjacent to Treated Tumors  Voir?

To evaluate the safety of irreversible electroporation (IRE) on the sciatic nerve after IRE ablation of adjacent tumor.
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Monolateral Pterional Keyhole Approaches to Bilateral Cerebral Aneurysms: Anatomy and Clinical Application  Voir?

To study the anatomy and clinical application of monolateral pterional keyhole approaches for treating bilateral cerebral aneurysms.
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Association of ACVRL1 Genetic Polymorphisms with Arteriovenous Malformations: A Case-Control Study and Meta-Analysis  Voir?

To investigate the association between polymorphisms in the gene encoding activin receptorlike kinase 1 (ACVRL1) with brain arteriovenous malformations (BAVMs) using a case-control study in a Chinese Han population, followed by a meta-analysis of the published literature.
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Results of Combined Intraventricular Neuroendoscopic Procedures in 130 Cases with Special Focus on Fornix Contusions  Voir?

Increasing experience with intraventricular neuroendoscopic procedures shows good results in the combination of endoscopic third ventriculostomy (ETV) and tumor biopsy. Other possible combinations are mainly presented in subgroups in the literature. Here, we present our experience with combined intraventricular procedures within 1 setting over the last 2 decades.

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Staged Stenting with or without Additional Coils after Conventional Initial Coiling of Acute Ruptured Wide-Neck Intracranial Aneurysms  Voir?

Stent-assisted coiling technique has been more and more adopted in the treatment of intracranial aneurysms and has been shown to improve long-term angiographic results; however, the treatment is relatively contraindicated in acutely ruptured aneurysms for its ischemic and hemorrhagic complications. Staged stenting after conventional coiling has emerged as a potential treatment strategy for ruptured wide-neck aneurysms. This study assessed the safety and efficacy of coiling in the acute phase followed by delayed stenting for ruptured wide-neck intracranial aneurysms.

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Minimally Invasive Versus Open Surgery for Lumbar Synovial Cysts  Voir?

Lumbar synovial cysts are relatively infrequent. Historically, these benign lesions have been treated with open excision, sometimes associated with fusion. The aim of this study is to compare minimally invasive surgery (MIS) with open surgery (OS) for the treatment of lumbar synovial cysts.
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Flexible Ultrathin Endoscope Integrated with Irrigation Suction Apparatus for Assisting Microneurosurgery  Voir?

Endoscopy can observe the anatomical components in a deeply located and/or hidden area during neurosurgical procedures under the operating microscope. We have newly developed a flexible ultrathin endoscope integrated with irrigation suction apparatus (FUEISA) to visualize deeply located and/or hidden areas for assisting microneurosurgery.

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Implications of Antiangiogenic Therapy on Radiographic Assessment of Brain Tumors  Voir?

In a paper recently published in WORLD NEUROSURGERY, Arai et al1 discussed some unusual magnetic resonance imaging (MRI) appearances of a glioblastoma multiforme in a patient on chronic lenvatinib therapy (a multireceptor tyrosine kinase inhibitor [TKI] with a mainly antiangiogenic action) for thyroid cancer. Their work underscores how the intersection of radiographic and histologic assessments of treated brain tumors have an evolving role in the future of neuro-oncologic decision making. In their example the reduced vascularity of the tumor after antiangiogenesis therapy was less suggestive of glioma based on classical imaging patterns.

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Predicting Short-Term Outcome After Surgery for Primary Spinal Tumors Based on Patient Frailty  Voir?

Frailty, decreased physiologic reserve and increased vulnerability to stressors beyond what is expected for normal aging, is associated with increased risk of morbidity and mortality. The objective of this study was to develop a preoperative frailty index for patients undergoing surgery for primary spinal column tumors that predicts morbidity, mortality, and length of stay.

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Treatment of Large or Giant Cavernous Aneurysm Associated with Persistent Trigeminal Artery: Case Report and Review of Literature  Voir?

Primitive trigeminal artery (PTA) is the most common anomaly of primitive carotid-basilar anastomosis and is associated with cerebrovascular anomalies, such as aneurysm. Large or giant cavernous aneurysm associated with PTA is rare, and the treatment strategies differ in comparison with large or giant aneurysm without PTA. In this article, we report an unusual case of a giant cavernous aneurysm associated with PTA and review treatment strategies for large or giant cavernous aneurysm associated with PTA.

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Operative Management of Distal Anterior Cerebral Artery Aneurysms Through a Mini Anterior Interhemispheric Approach  Voir?

Distal anterior cerebral artery (DACA) aneurysms, also known as pericallosal artery aneurysms, are present in 1.5%–9% of all intracranial aneurysms. Here we characterize the important microsurgical anatomy of DACAs; describe the surgical approach to treating these aneurysms with a minimally invasive surgical technique, the mini anterior interhemispheric approach (MAIA); and examine the nuances of aneurysm clipping in this region.

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Initial Clinical Experience with AView—A Clinical Computational Platform for Intracranial Aneurysm Morphology, Hemodynamics, and Treatment Management  Voir?

The management of intracranial aneurysm (IA) is challenging. Clinicians often rely on varied and intuitively disparate ways of evaluating rupture risk that may only partially take into account complex hemodynamic and morphologic factors. We developed a prototype of a clinically oriented, streamlined, computational platform, AView, for rapid assessment of hemodynamics and morphometrics in clinical settings. To show the potential clinical utility of AView, we report our initial multicenter experience highlighting the possible advantages of morphologic and hemodynamic analysis of IAs.

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Spontaneous Hemorrhagic Glioblastoma Revealed by Arterial Spin Labeling  Voir?

We report a case of hemorrhagic tumor detected early by pseudocontinuous arterial spin labeling sequence when conventional magnetic resonance imaging sequences were not contributive.
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The Influence of Parkinson Disease on Lumbar Decompression Surgery: A Retrospective Case Control Study  Voir?

Parkinson disease (PD) is a major risk factor during spine surgery, and its frequency is increasing as the population ages. The study aim was to examine the influence of PD specifically on lumbar decompression surgery.
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Robotic Stereotactic Assistance (ROSA) Utilization for Minimally Invasive Placement of Intraparenchymal Hematoma and Intraventricular Catheters  Voir?

In patients with supratentorial spontaneous intracerebral hemorrhage, intrahematomal catheter placement may allow for intraclot thrombolysis and drainage. Robotic assistance may be used for the stereotactic placement of catheters.
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Distally Enlarged Feeding Artery Phenomenon in Intracranial Dural Arteriovenous Fistula: Alternative Access Route to Transarterial Intravenous Embolization  Voir?

Transvenous (TV) embolization is ideal for endovascular treatment of intracranial dural arteriovenous fistulas (DAVF). However, it is not always feasible because of various factors, and transarterial (TA) embolization could then be tried. We aimed to determine the incidence of distally enlarged feeding artery phenomenon and the major feeding artery in DAVF. If the TV approach is difficult and this phenomenon is observed, we could use this vessel for transarterial intravenous (TAIV) embolization as an endovascular treatment modality for DAVF.

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Craniospinal Germinomas in Patient with Down Syndrome Successfully Treated with Standard-Dose Chemotherapy and Craniospinal Irradiation: Case Report and Literature Review  Voir?

Patients with Down syndrome (DS) are more likely to develop chemotherapy-related complications. The standard treatment for these patients with cancer has not yet been established, and the risks of standard chemotherapy are unclear. In this paper, a rare case of multiple craniospinal germinomas in a patient with DS, which was successfully treated with standard-dose chemotherapy combined with craniospinal irradiation, is reported.

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A Tortuous Process of Surgical Treatment for a Large Calcified Chronic Subdural Hematoma  Voir?

Calcified chronic subdural hematoma (CCSDH) is a rare disease for which no standard approach to treatment has been established. Reports covering both burr hole trepanation and craniotomy for CCSDH are rare. Furthermore, infection of CCSDH after the burr hole trepanation has not been reported in the literature.

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Accuracy of Shape Irregularity and Density Heterogeneity on Noncontrast Computed Tomography for Predicting Hematoma Expansion in Spontaneous Intracerebral Hemorrhage: A Systematic Review and Meta-Analysis  Voir?

This systematic review and meta-analysis was aimed to evaluate the predictive values of shape irregularity and density heterogeneity of hematoma on noncontrast computed tomography (NCCT) for hematoma expansion (HE).
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Morbidity and Mortality of Meningioma Resection Increases in Octogenarians  Voir?

The incidence of meningioma has increased drastically recently, particularly in older adults. Surgical intervention has the potential to reduce neurologic symptoms and achieve favorable, long-term outcomes. There is considerable variability in the literature examining the relationship between age and outcomes after meningioma surgery. The objective of this study was to identify the relationship between age and postoperative complications after craniotomy for resection of meningioma.

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Asymptomatic Ischemic Risks in Microsurgical Clipping for Unruptured Intracranial Aneurysms in Anterior Circulation  Voir?

The ischemic risk in prophylactic treatments of unruptured intracranial aneurysms (UIAs) is a serious health concern.
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Stereoscopic Three-Dimensional Neuroanatomy Lectures Enhance Neurosurgical Training: Prospective Comparison with Traditional Teaching  Voir?

Stereoscopic three-dimensional (3D) imaging is increasingly used in the teaching of neuroanatomy and although this is mainly aimed at undergraduate medical students, it has enormous potential for enhancing the training of neurosurgeons. This study aims to assess whether 3D lecturing is an effective method of enhancing the knowledge and confidence of neurosurgeons and how it compares with traditional two-dimensional (2D) lecturing and cadaveric training.

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Early Outcomes of Endoscopic Contralateral Foraminal and Lateral Recess Decompression via an Interlaminar Approach in Patients with Unilateral Radiculopathy from Unilateral Foraminal Stenosis  Voir?

Percutaneous endoscopic contralateral interlaminar lumbar foraminotomy (PECILF) for lumbar degenerative spinal stenosis is an established procedure. Better preservation of contralateral facet joint compared with that of the approach side has been shown with uniportal bilateral decompression. The aim of this retrospective case series was to analyze the early clinical and radiologic outcomes of stand-alone contralateral foraminotomy and lateral recess decompression using PECILF.

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Radiologic Predictors for Extent of Resection in Pituitary Adenoma Surgery. A Single-Center Study  Voir?

Preoperative radiologic evaluation of pituitary adenomas is essential. Despite the efforts made to determine the achieved resection grade after pituitary adenoma surgery, there is a high level of disagreement among all the available classifications and measurement methods used. Our study aimed to determine pituitary adenoma imaging features, easily obtained from preoperative magnetic resonance, which could be used as resection predictor variables. Second, we analyzed the usefulness of the ellipsoid method in pituitary adenoma volume determination.

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Successful Treatment with Microvascular Decompression Surgery of a Patient with Hemiparesis Caused by Vertebral Artery Compression of the Medulla Oblongata: Case Report and Review of the Literature  Voir?

There are few reports on hemiparesis caused by vascular medullary compression, which can occur because of dolichoectasia of the vertebrobasilar arterial system. In this article, we report a case of vertebral artery compression of the medulla oblongata in a 67-year-old woman.
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Spinal Hydatid Cyst Disease  Voir?

A hydatic cyst (HC) is a zoonotic infection affecting the liver and lungs, with rare spinal involvement. We discuss the long-term results in 8 patients with spinal HC who were monitored at our clinic for 7 to 15 years.
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Simple Lateral Suboccipital Approach and Modification for Vertebral Artery Aneurysms: A Study of 52 Cases Over 10 Years  Voir?

Complex skull base approaches are frequently used to treat intracranial vertebral artery (VA) and proximal posterior inferior cerebellar artery (PICA) aneurysms. These complex procedures are associated with higher risk of neurovascular injury. Hence, a less-invasive surgical approach is needed to improve the efficacy and safety of treatment.

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Hyponatremia in Traumatic Brain Injury: A Practical Management Protocol  Voir?

Hyponatremia (defined as serum sodium <135 mEq/L) is the most common electrolyte abnormality in traumatic brain injury (TBI) and is also an independent predictor of poor neurologic outcome. The reported incidence of hyponatremia varies widely in literature reports, and there is continuing difficulty in clearly differentiating between the 2 common causes of hyponatremia with natriuresis: the syndrome of inappropriate antidiuretic hormone secretion (SIADH) and cerebral salt wasting (CSW). We encounter hyponatremia frequently in our practice, and we therefore decided to review data from our center to estimate the incidence of hyponatremia and the results of our management strategies, and attempt to formulate simple guidelines for the correction of hyponatremia in TBI.

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Acquired Chiari I Malformation with Syringomyelia Secondary to Colloid Cyst with Hydrocephalus—Case Report and Review of Literature  Voir?

Acquired Chiari malformation and associated syringomyelia have been previously described following lumbar puncture/drainage, lumboperitoneal shunts, and spontaneous cerebrospinal fluid leakage. In addition to these etiologies, space-occupying lesions such as meningiomas, epidermoid cysts, medulloblastomas, and arachnoid cysts are rare causes of acquired Chiari malformation and syringomyelia. We report a rare case of colloid cyst with hydrocephalus causing secondary Chiari malformation with syringomyelia.

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A Pilot Study of the Level of Evidence and Collaboration in Published Neurosurgical Research  Voir?

Large-scale studies analyzing neurosurgical published research are lacking. This pilot study was designed to assess feasibility of an ongoing annual neurosurgical literature and research analysis of published articles in English-language neurosurgery journals.
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Medullary Decompression by Sling Repositioning of Vertebral Artery with Operative Video  Voir?

Vascular compression of the medullary pyramid resulting in neurologic compromise is rare; therefore diagnosis is difficult and ultimately delayed. Most patients present with a combination of cranial nerve, autonomic, and/or motor and sensory dysfunction. Presentation with a single sign such as hemiparesis is rare. The low number of cases reported has made it impossible to define a standard treatment for this unusual disorder.

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Altered Expression of MicroRNA-15a and Kruppel-Like Factor 4 in Cerebrospinal Fluid and Plasma After Aneurysmal Subarachnoid Hemorrhage  Voir?

Cerebral vasospasm (CVS) is a major determinant of prognosis in patients with subarachnoid hemorrhage (SAH). Alteration in the vascular phenotype contributes to development of CVS. However, little is known about the role of microRNAs (miRNAs) in the phenotypic alteration after SAH. We investigated the expression profile of miRNAs and the chronologic changes in the expression of microRNA-15a (miR-15a) and Kruppel-like factor 4 (KLF4), a potent regulator of vascular phenotype modulation that modulates the expression of miR-15a, in the plasma and cerebrospinal fluid (CSF) of patients with SAH.

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Incidence of Postoperative Hematomas Requiring Surgical Treatment in Neurosurgery: A Retrospective Observational Study  Voir?

We aimed to characterize the occurrence of postoperative hematoma (POH) after neurosurgery overall and according to procedure type and describe the prevalence of possible confounders.
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Cervical En-Plaque Extradural Meningioma Involving Brachial Plexus  Voir?

Meningioma is one of the commonest spinal tumors, with a predilection for intradural occurrence. Its occurrence as an extradural, en plaque variety with extension into the brachial plexus is unusual.
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Clinical Manifestations of Isolated Chronic Middle Cerebral Artery Occlusion in Relation to Angiographic Features  Voir?

Isolated chronic middle cerebral artery occlusion (ChMCAO) is not a rare condition and is known to cause hemodynamic stroke. The purpose of this study was to evaluate differences in clinical manifestations and prognosis of isolated ChMCAO in relation to angiographic features.
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Current Status of Worldwide Use of Patient-Reported Outcome Measures (PROMs) in Spine Care  Voir?

Patient-reported outcome measures (PROMs) are the most widely accepted means of measuring outcomes after spine procedures. We sought to determine the current status of worldwide use of PROMs in Latin America (LA), Europe (EU), Asia Pacific (AP), North America (NA), and Middle East (ME) to determine the barrier to its full implementation.

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Chronologic Evaluation of Cerebral Hemodynamics by Dynamic Susceptibility Contrast Magnetic Resonance Imaging After Indirect Bypass Surgery for Moyamoya Disease  Voir?

Although indirect bypass surgery is an effective treatment option for patients with ischemic-onset moyamoya disease (MMD), the time point after surgery at which the patient's hemodynamic status starts to improve and the time point at which the improvement reaches a maximum have not been known. The objective of the present study is to evaluate the hemodynamic status time course after indirect bypass surgery for MMD, using dynamic susceptibility contrast–magnetic resonance imaging (DSC-MRI).

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Minimally Invasive Treatment for a Sacral Tarlov Cyst Through Tubular Retractors  Voir?

Tarlov cysts (TC) are focal dilations of arachnoid and dura mater of the spinal posterior nerve root sheath that appear as cystic lesions of the nerve roots typically in the lower spine, especially in the sacrum, which can cause radicular symptoms when they increase in size and compress the nerve roots. Different open procedures have been described to treat TCs, but no minimally invasive procedures have been described to effectively address this pathology.

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Lumbosacral Subdural Hematoma After Glioblastoma Multiforme Resection: Possible Radiographic Evidence for the Downward Migration of Intracranial Blood  Voir?

Spinal subdural hematomas (SSDHs) are rare and usually associated with bleeding diatheses, trauma, iatrogenic injury, spinal vascular malformations, or intraspinal tumors.
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Impact of Onyx Embolization on Radiosurgical Management of Cerebral Arteriovenous Malformations: Treatment and Outcome  Voir?

Stereotactic radiosurgery (SRS) is a well-established treatment modality for cerebral arteriovenous malformations (AVMs). The main limiting factor in the radiosurgical treatment of AVMs is the volume of the nidus, with high-grade lesions often requiring combined treatment to reduce the SRS target volume. To overcome this limitation, we have been using a combined treatment approach consisting of endovascular embolization with Onyx followed by SRS.

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A Secure Approach to the Inferior Horn Using the Deep Medullary Vein as an Anatomic Guide  Voir?

Safe entry to the inferior horn is required for a selective approach to the medial temporal region. This can be challenging sometimes for inexperienced surgeons. Our objective was to verify the usefulness of the deep medullary vein (DMV) as an intraoperative landmark for safely entering the inferior horn during the transsylvian selective approach to the mesial temporal region.

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Medical Training and the Brain Death Exam: A Single Institution's Experience  Voir?

Clinicians may have limited opportunities to perform neurological determination of death (NDD, or brain death) certification during their training. This study aimed to evaluate the level of resident exposure to the brain death exam at a large-volume donor hospital.
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Ethnicity, Race, and Postoperative Stroke Risk Among 53,593 Patients with Asymptomatic Carotid Stenosis Undergoing Revascularization  Voir?

The incidence of postoperative stroke after carotid endarterectomy is an uncommon event, and differences by racial and ethnic subgroups are not described fully in the literature.
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Marginal En Bloc Resection of C2–C3 Chordoma with Bilateral Vertebral Artery Preservation and Mesh Cage Reconstruction with Review of Previously Published Cases  Voir?

Chordomas arise from remnants of the notochord and occur throughout the neuroaxis. En bloc resection of chordomas can prove especially challenging in the upper cervical spine secondary to the unique structural anatomy and intimate relationship to the vertebral arteries and spinal cord.
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Cerebrospinal Fluid Leak Rhinorrhea after Systemic Erlotinib Chemotherapy for Metastatic Lung Cancer: A Familiar Problem from an Unfamiliar Culprit  Voir?

Cerebrospinal fluid (CSF) rhinorrhea after medical therapy for pituitary prolactinoma is a rare but well-described phenomenon. To our knowledge, no CSF leaks have been reported after targeted medical treatment of pituitary or anterior skull base metastases. We report this unusual case to raise awareness of spontaneous CSF leaks in the setting of skull base metastatic disease.

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Endoscopic Transsphenoidal Approach for Acromegaly with Remission Rates in 401 Patients: 2010 Consensus Criteria  Voir?

Transsphenoidal surgery is the first-choice treatment for acromegaly. Postoperative remission is an important predictor of outcome. Various factors have been described as markers of remission: preoperative mean growth hormone (GH) and insulin-like growth factor-1 levels, cavernous sinus invasion, tumor size, extrapseudocapsular resection, and experience of the surgeon.

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Quantitative Comparison of Three Endoscopic Approaches to the Parasellar Region: Laboratory Investigation  Voir?

Endoscopic endonasal transsphenoidal and contralateral sublabial transmaxillary approaches are used for approaching parasellar lesions. The aim of this anatomical study was to compare endoscopic endonasal uninostril and binostril (contralateral) and contralateral sublabial transmaxillary approaches via a quantitative analysis of exposure limits and instrument working avenues.

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Anterior Lumbar Corpectomy with Expandable Titanium Cage Reconstruction: A Case Series of 42 Patients  Voir?

Burst fractures involve the anterior and middle columns with an intact posterior column. Deforming forces are magnified at areas of transition, making the thoracolumbar junction highly susceptible to injury.
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Single-Step Resection of an Intraosseous Meningioma and Cranial Reconstruction: Technical Note  Voir?

Simultaneous tumor resection and cranial reconstruction can be a challenging task. Surgical navigation is an indispensable tool in making this single-step procedure possible. In this technical note, we describe a new technique for this procedure to ensure a precise resection and optimal fit of the implant in a patient with an intraosseous meningioma.

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Moyamoya Vasculopathy in PHACE Syndrome: Six New Cases and Review of the Literature  Voir?

PHACE syndrome (Posterior fossa malformations, large cervicofacial infantile Hemangiomas, Arterial anomalies, aortic coarctation and Cardiac abnormalities, and Eye abnormalities) is a neurocutaneous disorder including posterior fossa malformations, hemangiomas, arterial lesions, cardiac defects, and eye abnormalities. PHACE arteriopathies may be progressive and recently have been categorized based on the risk of acute ischemic stroke, increasing attention to the potentially devastating consequences of cerebrovascular complications in this syndrome.

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Comparison of Unilateral and Bilateral Craniotomy for the Treatment of Bilateral Middle Cerebral Artery Aneurysms: Anatomic and Clinical Parameters and Surgical Outcomes  Voir?

To compare 2 craniotomy approaches (unilateral and bilateral) in terms of anatomic and clinical parameters and surgical outcomes.
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Transsphenoidal Surgery for Mixed Pituitary Gangliocytoma-Adenomas  Voir?

Most sellar gangliocytomas are discovered with a concurrent pituitary adenoma, also known as a mixed gangliocytoma-adenoma (MGA). MGAs are rare, with fewer than 100 cases reported in the literature to date and only 1 previously documented surgical series. Because MGAs are radiologically indistinguishable from pituitary adenomas, they are often diagnosed after surgery. Combined with the paucity of clinical outcome data for these tumors, this makes their diagnosis and management challenging. Here we describe the clinical presentation and outcomes of 10 individuals who were diagnosed with a MGA at a single institution.

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Why Does the Health-Related Quality of Life in Idiopathic Normal-Pressure Hydrocephalus Fail to Improve Despite the Favorable Clinical Outcome?  Voir?

Occasionally, a favorable clinical disease-specific outcome does not reflect into improved generic health-related quality of life (HRQoL) in patients with idiopathic normal-pressure hydrocephalus (iNPH) at 1 year after the installation of a cerebrospinal fluid shunt. Our aim was to identify factors causing this discrepancy.

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Sacral-Alar-Iliac Fixation in Children with Neuromuscular Scoliosis: Minimum 5-Year Follow-Up  Voir?

To investigate the 5-year outcomes of children with neuromuscular scoliosis treated with sacral-alar-iliac screws.
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Motor Cortex Stimulation in Patients Suffering from Chronic Neuropathic Pain: Summary of Expert Meeting and Premeeting Questionnaire, Combined with Literature Review  Voir?

Motor cortex stimulation (MCS) was introduced in the early 1990s by Tsubokawa and his group for patients diagnosed with drug-resistant, central neuropathic pain. Inconsistencies concerning the details of this therapy and its outcomes and poor methodology of most clinical essays divide the neuromodulation society worldwide into “believers” and “nonbelievers.” A European expert meeting was organized in Brussels, Belgium by the Benelux Neuromodulation Society in order to develop uniform MCS protocols in the preoperative, intraoperative, and postoperative courses.

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Stereotactic Radiosurgery of Central Skull Base Meningiomas—Volumetric Evaluation and Long-Term Outcomes  Voir?

Complete resection of a central skull base meningioma (CSM) is possible, but it is often associated with high morbidity. Stereotactic radiosurgery (SRS) plays an appreciable role in the management of skull base meningiomas. This study aims to apply volumetric methods to assess the CSM response after SRS and correlate it with clinical outcomes.

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Short-Term Outcome Comparison Between Full-Endoscopic Interlaminar Approach and Open Minimally Invasive Microsurgical Technique for Treatment of Lumbar Disc Herniation  Voir?

To compare postoperative pain control and functional outcome between full-endoscopic interlaminar approach (FEIA) and open minimally invasive microsurgical technique (MMST) for lumbar discectomy.
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Joint Capsule–Like Intracranial Osteochondroma Mimicking Cystic Meningioma  Voir?

This report provides the first representative images of an intracranial osteochondroma with a cystic component mimicking cystic meningioma. A 40-year-old male presented at our outpatient clinic with decreased sensation in his right upper extremity. Preoperative computed tomography showed a tumor with a cystic meningioma–like appearance and prominent calcifications. On magnetic resonance imaging, calcification of the lesion was suggested by the T2-weighted image; weak enhancement was seen on the T1-weighted image.

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Quantitative Analysis of Intracranial Vertebrobasilar Dissecting Aneurysm with Intramural Hematoma After Endovascular Treatment Using 3-T High-Resolution Magnetic Resonance Imaging  Voir?

Quantitative measurements of intracranial vessel walls are reliable in 3-T high-resolution magnetic resonance imaging (HR-MRI). However, few reports have assessed the arterial wall after endovascular treatment (EVT) by 3-T HR-MRI. This study aimed to quantitatively analyze vessel walls in vertebrobasilar artery dissecting aneurysms after EVT.

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The Effects of Combined Intraoperative Monitoring of Abnormal Muscle Response and Z-L Response for Hemifacial Spasm  Voir?

Microvascular decompression (MVD) is the most effective treatment for hemifacial spasm (HFS). During MVD surgery, abnormal muscle response (AMR) is widely used. Z-L response (ZLR) is a new monitoring method for HFS. We compared the effectiveness of AMR plus ZLR and simple AMR.
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Remote Thoracic Myelopathy From a Spinal Dural Arteriovenous Fistula at the Craniocervical Junction: Case Report and Review of Literature  Voir?

The craniocervical junction is a rare location for spinal dural arteriovenous fistulas (dAVFs). Typically, fistulas at this location present with findings related to intracranial cortical venous reflux or cervical myelopathy. We present a case of craniocervical junction dAVF with isolated clinical and radiographic findings of thoracolumbar myelopathy.

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Nontraumatic Multiple Vertebral Compression Fractures Induced by Primary Hyperparathyroidism: A Case Report and Literature Review  Voir?

Primary hyperparathyroidism (PHPT) is one of the causes of osteoporosis and is known to increase the fracture risk of bone. However, multiple vertebral compression fracture because of PHPT is extremely rare.
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Radiologic Features and Surgical Strategy of Hemangioblastomas with Enhanced Cyst Wall  Voir?

Hemangioblastomas with enhanced cyst walls represent a rare radiologic presentation of hemangioblastomas with poor understandings. We aimed to summarize the clinical and radiologic features, important differential diagnosis, surgical strategy, and clinical outcome of this rare entity.
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Self-Made, Cost-Reducing Hemostatic Agent for Use in Spine Surgery  Voir?

Operative bleeding complications can lead to patient morbidity and mortality as well as longer and increased hospitalization costs. Matrix hemostatic sealants are used commonly to shorten the time to hemostasis, operative times, and the need for blood transfusion. Commercially available hemostatic powders are used in spine surgery because of their ability to conform to wounds and decrease bleeding in difficult-to-access surgical sites. Hospital costs for these agents are variable and are dependent on negotiated institutional contracted prices.

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Endoscopic Middle Cranial Fossa Reconstruction with a Subtemporal Keyhole  Voir?

Skull base reconstruction is an essential technique for repairing cerebrospinal fluid (CSF) leakage. A reliable method for middle cranial fossa (MCF) reconstruction with minimal invasiveness has not been reported. An initial case of endoscopic MCF reconstruction with a subtemporal keyhole is described.

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Complete Reversibility of the Chiari Type II Malformation After Postnatal Repair of Myelomeningocele  Voir?

It was believed that Chiari type II malformation (CM-II) was always present in a myelomeningocele (MMC). In fact, it is associated in about 80% of cases. Improvement of the hindbrain herniation after prenatal closure of MMC has challenged the idea that this condition was irreversible. Only 2 studies report ascent of the cerebellar tonsil after postnatal closure. This work aimed to study a large group of patients with MMC who benefited from a postnatal repair to evaluate the rate of long-term total reversibility of CM-II.

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Surgical Management and Outcomes of Intracranial Chondromas: a Single-Center Case Series of 66 Patients  Voir?

Management of intracranial chondromas (ICDs) is difficult. This study aims to propose a tailored management strategy based on our management of ICDs.
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Neuroprotective Effects of Valproic Acid in a Rat Model of Cauda Equina Injury  Voir?

Histone deacetylase inhibitors, including valproic acid (VPA), are promising therapeutic interventions in neurological disorders and play an important role in synaptic activity and neuronal function.
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Spine Navigation Based on 3-Dimensional Robotic Fluoroscopy for Accurate Percutaneous Pedicle Screw Placement: A Prospective Study of 66 Consecutive Cases  Voir?

Minimally invasive spine surgery is associated with obstructed visibility of anatomic landmarks and increased radiation exposure, leading to higher incidence of pedicle screw mispositioning. To address these drawbacks, intraoperative 3-dimensional fluoroscopy (io3DF) and navigation are being increasingly used. We aimed to present our dedicated multifunctional hybrid operating room (HyOR) setup and evaluate the accuracy and safety of io3DF image-guided spinal navigation in transforaminal lumbar interbody fusion with percutaneous pedicle screw (PPS) placement.

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Residual Deformity After Anterior Cervical Discectomy and Fusion for Unstable Hangman's Fractures  Voir?

Anterior cervical discectomy and fusion (ACDF) is a commonly used surgery for unstable hangman's fractures. This study investigated the rate of residual deformity after ACDF for these fractures and the effect of residual deformity on clinical and radiologic outcomes.
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Models of Mortality and Morbidity in Severe Traumatic Brain Injury: An Analysis of a Singapore Neurotrauma Database  Voir?

Current prognostic models for traumatic brain injury (TBI) are developed from diverse historical data sets. We aimed to construct a prognostication tool for patients with severe TBI, as this group would benefit most from an accurate model.
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Decompressive Cranioplasty in a Patient with Osteopetrosis  Voir?

Osteopetrosis is a heterogeneous group of uncommon congenital disorders that causes bony sclerosis and remodeling. Patients who are symptomatic can show significant neurologic consequences with the involvement of cranial nerves and symptoms of increased intracranial pressure (ICP).
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On Protecting Young People's Brains  Voir?

In “Sport-Related Structural Brain Injury: 3 Cases of Subdural Hemorrhage in American High School Football,”1 the group from Vanderbilt's Sports Concussion Center and Department of Neurological Surgery report 3 cases of subdural hemorrhage in high school football athletes treated at their institution, occurring in 1 athletic season. The authors acknowledge their series to be atypical, due to the rarity of such injuries. Two of 3 cases had prior concussion within the same season, both requiring surgery.

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Extensive Mirror-Image Neurofibromas of Entire Spine Resulting in Spastic Tetraplegia  Voir?

Neurofibromatosis 1 (NF1) is associated with increased incidence of spinal tumors including neurofibromas. The majority of NF1-associated spine neurofibromas are asymptomatic; however, a minority of patients will experience neurologic symptoms that can range from mild paresthesia, radiculopathy, myelopathy, and focal weakness to quadriplegia in extreme cases.We present a 21-year-old male diagnosed with NF1 in infancy and followed for multiple mirror-image neurofibromas involving the entire spine.

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Regression of Recurrent High-Grade Glioma with Temozolomide, Dexamethasone, and Levetiracetam: Case Report and Review of the Literature  Voir?

Treatment options for recurrent glioma of the brain include chemotherapy, radiotherapy, surgery, and palliation. Temozolomide appears to be effective in patients with recurrent high-grade gliomas.
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Recurrent Bleeding After Perimesencephalic Hemorrhage  Voir?

Perimesencephalic hemorrhage (PMH) is a type of subarachnoid hemorrhage with excellent long-term outcomes. Only 1 well-documented case of in-hospital rebleeding after PMH is described in the literature, which occurred after initiating antithrombotic treatment because of myocardial ischemia. We describe a patient with PMH without antithrombotic treatment who had 2 episodes of recurrent bleeding on the day of ictus. To validate the radiologic findings, we conducted a case-control study. Six neuroradiologists and 2 neuroradiology fellows performed a blinded assessment of serial unenhanced head computed tomography (CT) scans of 8 patients with a perimesencephalic bleeding pattern (1 index patient, 6 patients with PMH, 1 patient with perimesencephalic bleeding pattern and basilar artery aneurysm) to investigate a potential increase in amount of subarachnoid blood.

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Cytotoxic and Apoptogenic Effects of Cyanidin-3-Glucoside on the Glioblastoma Cell Line  Voir?

Glioblastoma multiforme (GBM) is the most prevalent and aggressive primary cerebral tumor. The median survival time is 15 months despite maximum treatment because the tumor is resistant to most therapeutic modalities. Several studies have indicated chemopreventive and chemotherapeutic activity of cyanidin-3-glucoside (C3G) as an anthocyanin component. We aimed to illustrate the cytotoxic and apoptogenic effects of C3G in the U87 cell line (human GBM cell line).

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Transfer of Learning from Practicing Microvascular Anastomosis on Silastic Tubes to Rat Abdominal Aorta  Voir?

Learning to perform microvascular anastomosis is difficult. Laboratory practice models using artificial vessels are frequently used for this purpose. However, the efficacy of such practice models has not been objectively assessed for the performance of microvascular anastomosis during live surgical settings. This study was conducted to assess the transfer of learning from practicing microvascular anastomosis on tubes to anastomosing rat abdominal aorta.

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Endoscopic Endonasal Surgery for Treatment of Pituitary Apoplexy: 16 Years of Experience in a Specialized Pituitary Center  Voir?

Symptomatic pituitary apoplexy is a rare but life-threatening condition caused by sudden hemorrhage or infarction of a pituitary adenoma. In the current study, we aim to evaluate the clinical presentation, management, and clinical outcomes in a cohort of patients who were treated for this condition in our center in the last 16 years.

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Prognostic Factors and Comparison of Conservative Treatment, Percutaneous Vertebroplasty, and Open Surgery in the Treatment of Spinal Metastases from Lung Cancer  Voir?

Spinal metastases from lung cancer could result in life-threatening consequences. Few studies report the prognostic factors and compare different treatments in patients with spinal metastases from lung cancer.
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The Volume of the Third Ventricle as a Prognostic Marker for Shunt Dependency After Aneurysmal Subarachnoid Hemorrhage  Voir?

Hydrocephalus is a common sequelae of aneurysmal subarachnoid hemorrhage (aSAH). However, in daily routine it is difficult to predict a patient's need for ventricular shunt placement in the course of the disease.
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Soluble Fms-Like Tyrosine Kinase 1 (sFlt-1) and Risk of Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage  Voir?

The molecular mechanisms underlying cerebral vasospasm and delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (aSAH) are incompletely understood. We hypothesized that circulating antiangiogenic factors, such as soluble Fms-like tyrosine kinase 1 (sFlt-1) and soluble transforming growth factor β coreceptor, soluble endoglin (sEng), are important markers of their pathophysiology.

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Occipital Artery to Middle Cerebral Artery Bypass: Operative Nuances  Voir?

Superficial temporal artery (STA)–middle cerebral artery (MCA) anastomosis is a common procedure for vascular neurosurgeons, and it is used in a variety of diseases. However, there are cases in which the STA is absent or is too hypoplastic to be used as a donor for revascularization. Occipital artery (OA)–MCA bypass may be a treatment option in these cases.

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Staged Trapping of Traumatic Basilar Trunk Pseudoaneurysm: Case Report and Review of Literature  Voir?

Traumatic intracranial aneurysms (TICAs) of the posterior circulation in the pediatric populations are rare. Only a few reports in the literature document basilar artery TICA in the pediatric population. These cases were typically associated with a clival fracture and commonly diagnosed weeks to months after trauma. We present a case of a patient with a basilar TICA diagnosed after a motor vehicle collision treated with staged trapping and review of the literature.

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Spinal Cord Astrocytoma with Isocitrate Dehydrogenase 1 Gene Mutation  Voir?

In 2016, the World Health Organization updated its classification of tumors, adding genetic profiles to the conventional histopathologic typing.
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Revascularization Operation for Moyamoya Disease with Concurrent von Willebrand Disease  Voir?

Although extracranial-intracranial (EC-IC) bypass is an effective treatment strategy for symptomatic moyamoya disease, surgeons need to be cautious regarding the possibility of postoperative hemorrhagic complications in patients with a concurrent coagulation disorder. Here, we describe a case of EC-IC bypass for moyamoya disease concurrent with von Willebrand disease type 1.

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Fluorescence Behavior and Dural Infiltration of Meningioma Analyzed by 5-Aminolevulinic Acid–Based Fluorescence: Operating Microscope Versus Mini-Spectrometer  Voir?

To compare fluorescence intensity of tumor specimens, as measured by a fluorescence-guided surgery microscope and a spectrometer, to evaluate tumor infiltration of dura mater around meningiomas with help of these 2 different 5-aminolevulinic acid (5-ALA)-based fluorescence tools, and to correlate fluorescence intensity with histopathologic data.

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Surgical Outcomes of Posterolateral Sulcus Approach for Spinal Intramedullary Tumors: Tumor Resection and Functional Preservation  Voir?

Selection of the access myelotomy is a key issue in surgery for spinal intramedullary tumors. This study focused on surgical outcomes with the posterolateral sulcus (PLS) approach, equivalent to dorsal root entry zone myelotomy.
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Fostering Student Interest in Neurologic Surgery: The University of Pittsburgh Experience  Voir?

Early involvement and research in neurosurgery can increase chances for medical students to matriculate successfully into residency. This study reports the creation of a Neurological Surgery Interest Group (NSIG) at the University of Pittsburgh School of Medicine and shares its activities over 2 academic years.

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Treating Cerebrospinal Fluid Rhinorrhea without Dura Repair: A Case Report of Posterior Fossa Choroid Plexus Papilloma and Review of the Literature  Voir?

Choroid plexus papilloma revealed by nontraumatic cerebrospinal fluid (CSF) rhinorrhea has only been described 5 times, to our knowledge, in the literature. The challenges in this situation are to recognize CSF leak, to rapidly understand the pathophysiology of the leak, and to choose the best treatment strategy in emergency. We report an original case of posterior fossa choroid plexus papilloma revealed by CSF leak. We then discuss the surgical strategy and the pathophysiology of CSF leak, which is explained, in this case, by both hyperproduction of CSF and local skull base erosion.

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The Quantitative and Functional Changes of Postoperative Peripheral Blood Immune Cell Subsets Relate to Prognosis of Patients with Subarachnoid Hemorrhage: A Preliminary Study  Voir?

It has been suggested that the preoperative (PRE) and postoperative (POST) immune system alteration triggered by aneurysmal subarachnoid hemorrhage (SAH) and surgical treatment itself may affect patients' prognosis and contribute to POST complications. The mechanisms may be attributed to immune suppression–triggered infection or immune overreaction–triggered aseptic inflammation. In this study, we investigated the dynamic changes in peripheral immune cell subsets as well as the alterations of inflammatory cytokines in patients with aneurysmal SAH who received craniotomy and clipping surgery.

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Effects of Transcranial Direct-Current Stimulation on Neurosurgical Skill Acquisition: A Randomized Controlled Trial  Voir?

Recent changes in surgical training environments may have limited opportunities for trainees to gain proficiency in skill. Complex skills such as neurosurgery require extended periods of training. Methods to enhance surgical training are required to overcome duty-hour restrictions, to ensure the acquisition of skill proficiency. Transcranial direct-current stimulation (tDCS) can enhance motor skill learning, but is untested in surgical procedural training. We aimed to determine the effects of tDCS on simulation-based neurosurgical skill acquisition.

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Quality of Life and Work Capacity Are Unrelated to Approach or Complications After Pituitary Surgery  Voir?

Endoscopic pituitary surgery has shown favorable clinical outcomes. Less is known about the impact of surgical approaches on health-related quality of life (HRQoL) and work capacity. The present study was undertaken to compare transsphenoidal microscope-assisted surgery with endoscopic transsphenoidal surgery regarding preoperative and surgical factors for the final outcome of HRQoL and work capacity.

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Candida Meningitis After Transsphenoidal Surgery: A Single-Institution Case Series and Literature Review  Voir?

Candida meningitis after neurosurgical procedures is a rare but potentially devastating complication. The presentation of meningitis can be insidious in immunosuppressed patients and thus can be easily overlooked. Cerebrospinal fluid studies often resemble bacterial profiles, and cultures can be falsely negative. Candida albicans is the most common species identified in postsurgical Candida meningitis, and delay in diagnosis and treatment can be devastating. The standard induction therapy for Candida meningitis has been amphotericin B combined with flucytosine.

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Posttraumatic Uncal Herniation in a Conscious Patient  Voir?

The incidence of primary traumatic oculomotor nerve palsies in craniocerebral trauma is approximately 1.2% and is usually persistent and associated with loss of consciousness, other neurologic deficits, and skull base or orbital fractures. This case is a rare demonstration of complete left third nerve palsy from uncal herniation after trauma without any loss of consciousness.

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Moyamoya Disease in an 8-Year-Old Boy: Direct Bypass Surgery in a Province of Peru  Voir?

Pediatric moyamoya cases may be very arduous, even more so in a developing country, where access to specialized centers may be prevented by different factors.
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Reappraisal of Pediatric Diastatic Skull Fractures in the 3-Dimensional CT Era: Clinical Characteristics and Comparison of Diagnostic Accuracy of Simple Skull X-Ray, 2-Dimensional CT, and 3-Dimensional CT  Voir?

Diastatic skull fractures (DSFs) in children are difficult to detect in skull radiographs before they develop into growing skull fractures; therefore, little information is available on this topic. However, recent advances in 3-dimensional (3D) computed tomography (CT) imaging technology have enabled more accurate diagnoses of almost all forms of skull fracture. The present study was undertaken to document the clinical characteristics of DSFs in children and to determine whether 3D CT enhances diagnostic accuracy.

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Regression of Pineal Lesions: Spontaneous or Iatrogenic? A Case Report and Systematic Literature Review  Voir?

Tumors arising from the pineal region account for approximately 1% of intracranial neoplasms. We present a case of a previously healthy 5-year-old boy with an acute onset of headache. A magnetic resonance imaging (MRI) scan showed a pineal mass with aqueduct compression. The patient was scheduled for tumor resection. An endoscopic third ventriculostomy was performed in advance for the treatment of hydrocephalus. Afterwards, MRI showed a relevant regression of the pineal mass without specific treatment.

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Skull Metastasis from the Liver: Case Report and Literature Review  Voir?

Calvarial metastasis from liver cirrhosis in the absence of a primary focus is exceptionally rare. Few reports of metastases from hepatocellular carcinoma of an unknown primary focus have been published.
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Spinal Coccidioidomycosis: A Current Review of Diagnosis and Management  Voir?

Coccidioidomycosis is an invasive fungal disease that may present with extrathoracic dissemination. Patients with spinal coccidioidomycosis require unique medical and surgical management. We review the risk factors and clinical presentations, discuss the indications for surgical intervention, and evaluate outcomes and complications after medical and surgical management.

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Angiomatous Meningiomas Have a Very Benign Outcome Despite Frequent Peritumoral Edema at Onset  Voir?

Angiomatous meningioma (AM) is a rare subtype of meningioma characterized by highly vascular tumor tissue comprising predominantly variable sized hyalinized blood vessels. The aim of this study is to evaluate the clinical radiologic features of AM and the long-term prognosis in a single neurosurgical center.

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Long-Term Outcomes of Surgical Treatment in 181 Patients with Supratentorial Cerebral Cavernous Malformation–Associated Epilepsy  Voir?

To evaluate the efficacy of surgery as a treatment for supratentorial cerebral cavernous malformation–associated epilepsy (SCCMAE) and determine the factors that influence outcomes.
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A Retrospective Study of Thoracolumbar Fractures Treated with Fixation and Nonfusion Surgery of Intravertebral Bone Graft Assisted with Balloon Kyphoplasty  Voir?

Posterior fixation and fusion is the primary treatment for thoracolumbar fractures, although this treatment may sacrifice range of motion (ROM) to achieve stability, rather than treating the fracture itself. Two issues addressed when treating thoracolumbar fractures are 1) replacing the fractured vertebrae, especially the upper end plate of the injured vertebrae and 2) providing strong fixation with biomechanical stability and flexibility.

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Multimodal 18F-Fluciclovine PET/MRI and Ultrasound-Guided Neurosurgery of an Anaplastic Oligodendroglioma  Voir?

Structural magnetic resonance imaging (MRI) and histopathologic tissue sampling are routinely performed as part of the diagnostic workup for patients with glioma. Because of the heterogeneous nature of gliomas, there is a risk of undergrading caused by histopathologic sampling errors. MRI has limitations in identifying tumor grade and type, detecting diffuse invasive growth, and separating recurrences from treatment induced changes. Positron emission tomography (PET) can provide quantitative information of cellular activity and metabolism, and may therefore complement MRI.

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Percutaneous Biopsy of Lesions in the Cavernous Sinus: A Systematic Review  Voir?

A wide variety of lesions may develop in the cavernous sinus region, including tumors or pseudotumors of inflammatory origin. Sometimes imaging is insufficient to ascertain a pathologic diagnosis. Percutaneous biopsy performed through the foramen ovale route may aid therapeutic decision making, avoiding unnecessary open surgery when lesions are confirmed to be nonsurgical or unresectable. We conducted a systematic review to determine the efficacy of percutaneous biopsy of cavernous sinus lesions.

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Metastatic Basal Cell Adenocarcinoma of Submandibular Gland to the Spine: An Extremely Rare Condition  Voir?

Basal cell adenocarcinomas are rare malignant neoplasms of salivary glands, accounting for <1% of salivary gland tumors. Few cases of distant metastases have been reported.
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Thoracic Intradural-Extramedullary Epidermoid Tumor: The Relevance for Resection of Classic Subarachnoid Space Microsurgical Anatomy in Modern Spinal Surgery. Technical Note and Review of the Literature  Voir?

Intradural epidermoid tumors of the spinal cord are commonly associated with spinal cord dysraphism or invasive procedures. We report the particular relationships between spinal subarachnoid compartments and thoracic intradural-extramedullary epidermoid tumor, highlighting the relevant anatomic changes that may influence microsurgery.

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Factors Predicting Ventricle Volume Increase After Aneurysmal Clipping in Patients with Subarachnoid Hemorrhage  Voir?

Although many studies have evaluated risk factors associated with hydrocephalus after aneurysmal subarachnoid hemorrhage, specific ventricle volume changes after subarachnoid hemorrhage have not been evaluated. We sought to evaluate factors predicting ventricle volume enlargement in patients with aneurysmal subarachnoid hemorrhage by measuring ventricle volume with a validated, semiautomated tool.

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The Role of Antibiotic Prophylaxis in Shunt Surgery  Voir?

To determine whether antibiotic prophylaxis (AP) can reduce the postoperative infection rate and identify the risk factors for postoperative infection in shunt surgery.
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Comparison of Porcine and Bovine Collagen Dural Substitutes in Posterior Fossa Decompression for Chiari I Malformation in Adults  Voir?

Posterior fossa decompression surgeries for Chiari malformations are susceptible to postoperative complications such as pseudomeningocele, external cerebrospinal fluid (CSF) leak, and meningitis. Various dural substitutes have been used to improve surgical outcomes.
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Outcomes After Endoscopic Endonasal Resection of Craniopharyngiomas in the Pediatric Population  Voir?

Craniopharyngiomas have traditionally been treated via open transcranial approaches. More recently, endoscopic transsphenoidal approaches have been increasingly used; however, few case series exist in the pediatric population.
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Comparison of Different Sequences of Magnetic Resonance Imaging and Ultrasonography with Nerve Conduction Studies in Peripheral Neuropathies  Voir?

Peripheral neuropathies refer to a group of disorders in which there is damage to the nerves of the peripheral nervous system. Electrophysiologic studies are the main stay for the diagnosis of peripheral neuropathies. However, direct visualization of the nerves is possible with exact localization of site of disease with high-resolution ultrasonography (USG) and 3-Tesla magnetic resonance imaging (MRI) scanner, and newer magnetic resonance (MR) sequences.

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Mastoid Epidermoid Tumor and Associated Dural Arteriovenous Fistula with Venous Sinus Occlusion  Voir?

Dural arteriovenous fistula (DAVF) is an abnormal vascular connection between arterial and venous channels within dura mater. Although DAVFs have been linked to other types of intracranial tumors, this is the first case reporting the association between DAVF and an epidermoid tumor.
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Pilot Use of a Novel Tool to Assess Neurosurgical Capacity in Uganda  Voir?

There is a significant burden of unmet surgical need in many low- and middle-income countries (>80% in parts of Africa). This need is even larger for specialties such as neurosurgery. Surgical capacity tools have been developed and used to assess needs and plan for resource allocation. This study piloted a new tool to assess neurosurgical capacity and describes its use.

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Endovascular Thrombectomy Alone versus Combined with Intravenous Thrombolysis  Voir?

To date, no randomized trial has directly addressed the question of whether intravenous (IV) tissue plasminogen activator (tPA) improves outcomes in IV tPA-eligible patients who will eventually undergo endovascular therapy (EVT), or whether a direct EVT strategy is equally effective. We performed a systematic review and meta-analysis to compare the efficacy and safety of direct EVT versus endovascular treatment with IV tPA (EVT+IV tPA) in adults with acute ischemic stroke.

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Thoracic Arachnoid Cyst Made Symptomatic by Demyelination  Voir?

Spinal arachnoid cysts are uncommon distinct pouches of cerebrospinal fluid (CSF) or CSF-like fluid found adjacent to normal CSF spaces commonly extradural and rarely intradural. They are usually asymptomatic and discovered incidentally. We present a patient with rapid upper motor neuron neurologic deterioration over the course of 1 week. Findings on magnetic resonance imaging revealed various central nervous system demyelination lesions and thoracic arachnoid cyst with cord compression. This acute presentation, in the absence of trauma, is not in favor of the natural history of the intradural thoracic arachnoid cysts.

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Intradural-Extramedullary Capillary Hemangioma with Acute Bleeding: Case Report and Literature Review  Voir?

Capillary hemangiomas are benign vascular tumors. They are commonly founded in the vertebral bodies but very seldom in the spinal cord. The most common symptom at onset is long-lasting axial pain without neurologic deficit. In rare cases, the onset may be acute with neurological deficit due to an intratumoral hemorrhage.

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Cervical Cord-Canal Mismatch: A New Method for Identifying Predisposition to Spinal Cord Injury  Voir?

The risk for spinal cord injuries (SCIs) ranging from devastating traumatic injuries, compression because of degenerative pathology, and neurapraxia is increased in patients with congenital spinal stenosis. Classical diagnostic criteria include an absolute anteroposterior diameter of <12–13 mm or a Torg-Pavlov ratio of <0.80–0.82; however, these factors do not take into account the size of the spinal cord, which varies across patients, independent of canal size. Recent large magnetic resonance imaging studies of population cohorts have allowed newer methods to emerge that account for both cord and canal size by measuring a spinal cord occupation ratio (SCOR).

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Syringo-Subarachnoid Shunt for the Treatment of Persistent Syringomyelia Following Decompression for Chiari Type I Malformation: Surgical Results  Voir?

Approximately 30% of patients treated with foramen magnum decompression (FMD) for Chiari I–associated syringomyelia will show persistence, recurrence, or progression of the syrinx.
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Open Versus Minimally Invasive Surgery for Extraforaminal Lumbar Disk Herniation: A Systematic Review and Meta-Analysis  Voir?

Extraforaminal disk herniation (EDH) accounts for 3%–11% of all disk herniations. Despite the heterogeneity of spinal procedures, there is a paucity of literature comparing the outcomes from different surgical approaches.
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Significance of the Tentorial Alignment in Protecting the Occipital Lobe with the Poppen Approach for Tentorial or Pineal Area Meningiomas  Voir?

We aimed to identify the factors that can predict the risk of occipital lobe damage preoperatively when resecting tumors located at the tentorial or pineal regions with the occipital-transtentorial approach (Poppen approach).
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Varied Spectrum of Supratentorial Arteriovenous Malformations: Technical Challenges  Voir?

Supratentorial arteriovenous malformations (AVMs) are heterogeneous pathologic entities and require an intricate decision-making process for their management. We present 3 cases of supratentorial arteriovenous malformations with diverse clinical presentations and highlight the role of microsurgical resection in present-day multimodality treatments of arteriovenous malformations.

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First Case of Autonomic Dysreflexia Following Elective Lower Thoracic Spinal Cord Transection in a Spina Bifida Adult  Voir?

Spinal cord transection is a radical but effective treatment for highly selective cases of symptomatic spinal retethering in paraplegic spina bifida patients. Autonomic dysreflexia (AD) is a potentially life-threatening syndrome involving a dysregulated sympathetic discharge reflex commonly seen following cervical and high thoracic spinal cord injury, leading to a disconnect between autonomic pathways above and below the lesion that can lead to severe complications including uncontrolled hypertension, bradycardia, stroke, and potentially death.

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Anatomic Dissection of Arachnoid Membranes Encircling the Pituitary Stalk on Fresh, Non–Formalin-Fixed Specimens: Anatomoradiologic Correlations and Clinical Applications in Craniopharyngioma Surgery  Voir?

The anatomy of the arachnoid membranes and cisternal spaces around the pituitary stalk has not been yet exhaustively described and understood. In this study, we performed a detailed anatomic study on fresh, non–formalin-fixed cadavers of the arachnoid membranes encircling the pituitary stalk and correlate our anatomic findings with magnetic resonance imaging (MRI).

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Indeterminate Dendritic Cell Tumor in Thoracic Spine: A Case Report  Voir?

Indeterminate dendritic cell tumor (IDCT) is an extremely rare hematologic disorder with poorly understood pathogenesis. Occasionally encountered by hematologists, unusual presentations of IDCT have not been reported in the spine literature.
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Improving the Prognostic Value of Disease-Specific Graded Prognostic Assessment Model for Renal Cell Carcinoma by Incorporation of Cumulative Intracranial Tumor Volume  Voir?

We tested the prognostic value of cumulative intracranial tumor volume (CITV) in the context of a disease-specific Graded Prognostic Assessment (ds-GPA) model for renal cell carcinoma (RCC) patients with brain metastasis (BM) treated with stereotactic radiosurgery (SRS).
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A Retrospective Study of Clinical Outcomes After Endovascular Treatment in Acute Ischemic Stroke Patients with Complete Anterior Circulation Infarction in the Absence of Multimodal Computed Tomography  Voir?

To analyze the positive predictive value of large artery occlusion and clinical prognosis in acute ischemic stroke patients with total anterior circulation infarct (TACI) who underwent endovascular treatment in the absence of multimodal CT angiography or CT perfusion.
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Micro-Multileaf Collimator LINAC Radiosurgery for Vestibular Schwannomas  Voir?

This study evaluates the efficacy of linear accelerator (LINAC) radiosurgery using micro multi-leaf collimator technique (μMLC) in the treatment of a consecutive series of patients with vestibular schwannomas.
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WITHDRAWN: The modified impact factor; a letter to the editor  Voir?

This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause.The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy.
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WITHDRAWN: Outcomes After Anterior Lumbar Interbody Fusion Versus Transforaminal Lumbar Interbody Fusion for the Treatment of Symptomatic L5–S1 Spondylolisthesis: A Prospective, Multi-Institutional Comparative Effectiveness Study  Voir?

Available online 25 September 2015
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WITHDRAWN: Refining the Role for Evacuation of Spontaneous Intracerebral Hematomas: Results of STICH II  Voir?

The Publisher regrets that this article is an accidental duplication of an article that has already been published, DOI of original article: http://dx.doi.org/10.1016/j.wneu.2014.08.046. The duplicate article has therefore been withdrawn.The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy.

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Upcoming Events  Voir?

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Editor's Choices  Voir?

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Subscription Information  Voir?

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Editorial Board  Voir?

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Contents  Voir?

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Herb  Voir?

This month, December 2017, marks the end of an era. Herb Niemirow, publisher of WORLD NEUROSURGERY since its inaugural issue 8 years ago, is retiring from his post at Elsevier. Herb shepherded the birth of WORLD NEUROSURGERY and its transformation from the prior journal, SURGICAL NEUROLOGY. Herb and Mike Apuzzo, the journal's first Editor-in-Chief, had a vision. Together they established and nurtured the establishment and evolution of a phenomenal journal. I am certain that even they could not have envisioned the transformation that ensued.

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In Reply to the Letter to the Editor “Circumventricular Organ Origin of Hemangioblastoama; Hypothesis for Pathogenesis of Disease”  Voir?

Hemangioblastomas (HBs) are histologically benign tumors that occur almost exclusively in specific regions of the central nervous system, most commonly in the posterior fossa, accounting for ≥90% of HBs; 1%−5% of HBs are in the supratentorial regions, and only 30% of the supratentorial HBs are located in the pituitary stalk and tuber cinereum.1-4 Hitherto, its cytologic/histogenesis origins remain controversial. This hypothesis of the circumventricular organs (CVOs)’ origin of HBs provides us an interesting and new perspective to further study.

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In Reply to the Letter to the Editor “Fluorescein Sodium in Intracranial Meningioma Surgery”  Voir?

We read the comments by Schebesch et al1 about our recent publication with great interest. We thank the authors for their comments and indeed we think (as indicated in their letter to editor) sodium fluorescein (Na-Fl) in combination with a dedicated light filter has far more benefits than only increasing the extent of resection in glioma and metastasis surgery. Na-Fl can be practically used with the same videoangiography technique for the surgery of any type of extraaxial tumors. As we indicated in our publication,2 we used the same rationale as that in the study by Acerbi et al,3 in which they used Na-Fl for tumor demarcation in combination with ICG videoangiography for evaluating adjacent vascular structures and adopted the Na-Fl videoangiography technique used in the study by Lane et al,4 with some modifications.

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In Reply to the Letter to the Editor “Circumventricular Organ Origin of Hemangioblastoama; Hypothesis for Pathogenesis of Disease”  Voir?

We appreciate the thoughtful letter from Dr. Taghipour et al regarding our article, “Clinical Features and Surgical Outcomes in Patients with Cerebellopontine Angle Hemangioblastomas: Retrospective Series of 23 Cases.” They hypothesized that the area postrema and median eminence, which were considered circumventricular organs (CVOs), were the origin of the hemangioblastoma as they lacked the blood-blain barrier (BBB) and allowed free distribution of required cytokines into the arrested hemangioblasts, resulting in reactivation of the hemangioblasts and their transformation into the hemangioblastoma.

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In Reply to the Letter to the Editor “Enhancing Ethics in Peer Review Process”  Voir?

We would like to thank Dr. Agoramoorthy for taking the time to read and respond to our article. Certainly, several highly pertinent and thoughtful points were brought up. We agree wholeheartedly with the idea that flawed peer review processes are highly detrimental to the dissemination of good science and that resolution of this requires a collaborative effort on the part of journals, publishers, institutions, and individual authors.

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In Reply to the Letter to the Editor Regarding “Presence of a Malignant Tumor as a Novel Predictive Factor for Repeated Recurrences of Chronic Subdural Hematoma”  Voir?

We thank Drs. Safiri and Ashrafi-Asgarabad for their comments regarding our recent paper.1 We appreciate the careful review and suggestions on how to improve the methodologic aspect of the paper.
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In Reply to the Letter to the Editor “Ambulatory Surgery and Social Inequalities in Industrialized Countries”  Voir?

We have read with great interest the letter from Gaucher et al, which highlights a crucial point in the management of our most fragile and socially isolated patients.
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In Reply to the Letter to the Editor Regarding “Predictors of Shunt-Dependent Hydrocephalus After Aneurysmal Subarachnoid Hemorrhage? A Systematic Review and Meta-Analysis”  Voir?

We would like to thank Dr. Kanat for his interest in our previously published article in WORLD NEUROSURGERY.1 We agree with Dr. Kanat that evidence from experimental studies is crucial in identifying the predictors of hydrocephalus after subarachnoid hemorrhage (SAH) and developing treatment strategy against modifiable risk factors. Moreover, we believe that it is important to explain existing clinical findings with new experimental evidence.

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Circumventricular Organ Origin of Hemangioblastoama; Hypothesis for Pathogenesis of Disease  Voir?

We have read with interest the articles by Cheng et al1 entitled “Clinical Features and Surgical Outcomes in Patients with Cerebellopontine Angle Hemangioblastomas: Retrospective Series of 23 Cases” and Ma et al2 entitled “Neurosurgical Management of Brainstem Hemangioblastomas: A Single-Institution Experience with 116 Patients,” both published in WORLD NEUROSURGERY. These studies describe the clinical and imaging profile of hemangioblastoma in the cerebellopontine angle1 and the brainstem2 and describe the microsurgical management of the patients.

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Considerations in Meta-Analyses to Understand the Value of Intravenous Thrombolysis in Current, Guideline-Based, Endovascular Practice of Stroke Treatment  Voir?

We read the meta-analysis by Phan et al,1 “Endovascular thrombectomy alone versus combined with intravenous thrombolysis,” with enthusiasm. In their study, the authors address one of the central uncertainties relevant to the current practice of stroke treatment: What is the added value of pretreatment with intravenous thrombolysis to eligible patients treated with mechanical thrombectomy? While recognizing the study limitations, the authors present the following main results: 1) A strong trend towards favorable functional outcomes 2) without a change in mortality or 3) in the proportion of symptomatic intracerebral hemorrhage was noted in patients who received intravenous thrombolysis compared to those who did not before mechanical thrombectomy.

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Letter to the Editor Regarding “Presence of a Malignant Tumor as a Novel Predictive Factor for Repeated Recurrences of Chronic Subdural Hematoma”  Voir?

We were interested to read the paper authored by Hori et al1 that was published recently in WORLD NEUROSURGERY. The authors evaluated the significance of malignant tumors on chronic subdural hematomas (CSDH) recurrence, focusing particularly on the difference between a past versus present malignant tumor. They concluded that the presence of a malignant tumor can be a novel predictive factor for repeated CSDH recurrences. Although their study makes valuable contributions to the area, some methodologic issues need to be taken into account.

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In Reply to the Letter to the Editor Regarding “Relationship Between Koenig Depression Scale and Postoperative Outcomes, Ambulation, and Perception of Pain in Elderly Patients (≥65 Years) Undergoing Elective Spinal Surgery for Adult Scoliosis“  Voir?

The primary aim of this manuscript was to assess whether the Koenig Depression Scale (KDS) can identify depressed elderly patients undergoing elective spine surgery for deformity at risk for inferior postoperative outcomes. Using the cutoff for depression identified by the authors of the scale, we dichotomized patients into 2 cohorts—depressed and nondepressed. The subsequent analysis demonstrated that there was no difference in complication rates, ambulation ability, and pain scores between patients identified as depressed using the KDS and those identified as nondepressed.

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Enhancing Ethics in Peer Review Process  Voir?

The article titled “Retraction of Neurosurgical Publications: A Systematic Review” by Wang et al1 is interesting. The review portrays the increasing unethical trend in scientific writing that ranges from duplicate publication to plagiarism and from data manipulation to fake peer review. The peer review as such is part of the long-held science tradition to upgrade ethics since journals play an important role to transfer scientific information to society.

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In Reply to the Letter to the Editor “Feasibility of Using a Superficial Temporal Artery Graft in Internal Maxillary Artery Bypass”  Voir?

We would like to thank Dr. Wang et al1 for their thoughtful review of our recent paper. The authors raised several concerns regarding the feasibility of using the superficial temporal artery as an interposition graft (STAG) for the internal maxillary artery (IMA)–upper posterior circulation (UPC) bypass. Their concerns fall into 2 main categories: 1) inadequate caliber and 2) inadequate length of the STAG. They argue that the caliber of the STAG does not match those of the IMA and recipient UPC arteries.

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Feasibility of Using a Superficial Temporal Artery Graft in Internal Maxillary Artery Bypass  Voir?

We read with great interest the recent article by Meybodi et al1 in your esteemed journal regarding surgical anatomy and feasibility assessment of internal maxillary artery (IMA) to upper posterior circulation bypass with an interposed superficial temporal artery (STA) graft in a cadaveric study. In this high-quality and detailed article, the authors further studied the STA trunk as a graft conduit for an IMA bypass procedure following Arbag et al,2 obviating the need for cervical and arm incisions, avoiding potential technical and vascular complications, and decreasing the length of the procedure.

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Letter to the Editor Regarding “Relationship Between Koenig Depression Scale and Postoperative Outcomes, Ambulation, and Perception of Pain in Elderly Patients (≥65 Years) Undergoing Elective Spinal Surgery for Adult Scoliosis”  Voir?

We were interested to read the paper by Elsamadicy et al1 that was published in WORLD NEUROSURGERY. The authors tried to examine the power of Koenig Depression Scale (KDS) for identifying depressed elderly patients undergoing elective spine surgery for deformity at risk for inferior postoperative outcomes, including complication rates, ambulation ability, and patient-reported outcomes.1 The results suggested that there are no significant differences in complication rates, ambulation abilities, and follow-up visual analog scale scores between patients identified as depressed on the KDS (<4) compared with nondepressed (≥4) patients.

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Fluorescein Sodium in Intracranial Meningioma Surgery  Voir?

We read with great interest the article of Mehmet Osman Akçakaya et al1 about the possible benefit and feasibility of fluorescein sodium (FL) and the YELLOW 560 nm filter (YE560) in intracranial meningioma surgery. For the first time, the authors evaluated 30 patients with different localizations and histologic types of cerebral meningiomas, with special focus on the degree of intraoperative fluorescent staining. In 5 patients, FL was used for videoangiography, as these tumors either incorporated large vessels or were adjacent to major sinuses.

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Ambulatory Surgery and Social Inequalities in Industrialized Countries  Voir?

We greatly appreciated the recent study by Debono et al1 reporting the feasibility of dissociation between the length of hospitalization stay and quality of health care. Their results are very encouraging, but we must remain vigilant.
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Letter to the Editor Regarding “Efficacy of Early Surgery for Neurological Improvement in Spinal Cord Injury without Radiographic Evidence of Trauma in the Elderly”  Voir?

In the article by Inoue et al,1 the authors aim to compare the efficacy of early (<24 hours postinjury) versus late (>24 hours postinjury) surgery in patients age 65 years and older with spinal cord injury without radiographic evidence of trauma (SCIWORET). They concluded that that in elderly patients with SCIWORET, early surgery (within 24 hours of injury) can lead to more favorable neurologic improvements.

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Letter to the Editor Regarding “Predictors of Shunt-Dependent Hydrocephalus After Aneurysmal Subarachnoid Hemorrhage? A Systematic Review and Meta-Analysis”  Voir?

We read with great interest the article of Xie et al.1 They made a systematic search on hydrocephalus (HCP) after subarachnoid hemorrhage (SAH) and found 25 studies and some potential risk factors for shunt-dependent HCP after SAH, including age ≥50 years, female sex, high Hunt and Hess grade, Glasgow Coma Scale score ≤8, Fisher grade ≥3, acute HCP, external ventricular drainage insertion, intraventricular hemorrhage, postcirculation aneurysm, anterior communicating artery aneurysm, meningitis, and rebleeding.

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Dernière mise à jour : 22/11/2017 : 19:20


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