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Sommaires des Revues - New England Journal of Medecine

The New England Journal of Medicine: Search Results in Neurology\Neurosurgery


The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Neurology\Neurosurgery. NEJM (http://www.nejm.org) is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.


The Role of Science in Addressing the Opioid Crisis  Voir?

Opioid misuse and addiction is an ongoing and rapidly evolving public health crisis, requiring innovative scientific solutions. In response, and because no existing medication is ideal for every patient, the National Institutes of Health (NIH) is joining with private partners to launch an…
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Nystagmus from Wernicke’s Encephalopathy  Voir?

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Subarachnoid Hemorrhage  Voir?

Foreword. This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors’ clinical recommendations. Stage. A 17-year-old…

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Amyotrophic Lateral Sclerosis  Voir?

Amyotrophic lateral sclerosis (ALS) is a progressive, paralytic disorder characterized by degeneration of motor neurons in the brain and spinal cord. It begins insidiously with focal weakness but spreads relentlessly to involve most muscles, including the diaphragm. Typically, death due to…
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Unmasking Ptosis in Both Eyes  Voir?

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Cerebral Cavernous Malformations  Voir?

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Case 20-2017 — A 48-Year-Old Man with Weight Loss, Confusion, Skin Lesions, and Pancytopenia  Voir?

Presentation of Case. Dr. Robert H. Goldstein (Medicine): A 48-year-old man was seen in the emergency department of this hospital because of confusion. The week before this presentation, the patient, who was a lawyer, had traveled alone to Mexico for vacation. His family reported that he seemed to…

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Efficient Trial Design — FDA Approval of Valbenazine for Tardive Dyskinesia  Voir?

A well-executed development program that addresses both regulatory and clinical requirements is critical for making novel therapeutics available as quickly as possible to patients with unmet medical needs. In the case of valbenazine, which was recently approved by the U.S. Food and Drug…
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Case 19-2017 — A 53-Year-Old Woman with Leg Numbness and Weakness  Voir?

Presentation of Case. Dr. Kristyn M. Spera (Neurology): A 53-year-old woman with rheumatoid arthritis was admitted to this hospital because of progressive asymmetric hypoesthesia and weakness in the legs. The patient had been in her usual health until 4 months before this admission, when…
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Cluster-Randomized, Crossover Trial of Head Positioning in Acute Stroke  Voir?

The prognosis in patients with acute ischemic stroke is determined according to the location and size of the occluded cerebral vessel, the extent of collateral blood flow, and the time to reperfusion therapy. Small, nonrandomized studies have indicated that the lying-flat position (i.e. fully…

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Seesaw Nystagmus  Voir?

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Large Arachnoid Cyst  Voir?

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Trial of Minocycline in a Clinically Isolated Syndrome of Multiple Sclerosis  Voir?

After a first focal clinical demyelinating event (also called a clinically isolated syndrome), the risk of conversion to multiple sclerosis is high. Minocycline is a tetracycline antibiotic agent that has immune-modulating properties; preliminary data have shown activity of minocycline in patients…

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The Other Victims of the Opioid Epidemic  Voir?

I’d seen Jerry in pain before, but never like this. He lay prostrate on the gurney in the emergency department, his hands clenched in silent prayer. I laid an apologetic hand on his shoulder and told him we would do what we could to help. Then I logged in to the bedside computer to order his pain…

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Abuse-Deterrent Opioid Formulations — Putting the Potential Benefits into Perspective  Voir?

Death rates among middle-aged adults, the largest demographic group in the United States, are on the rise for the first time in several decades. This trend can largely be explained by an increase in drug-overdose deaths, the majority of which involve opioids. The opioid crisis has attracted…
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A 1980 Letter on the Risk of Opioid Addiction  Voir?

To the Editor: The prescribing of strong opioids such as oxycodone has increased dramatically in the United States and Canada over the past two decades. From 1999 through 2015, more than 183,000 deaths from prescription opioids were reported in the United States, and millions of Americans are now…

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Minocycline in Multiple Sclerosis — Compelling Results but Too Early to Tell  Voir?

Care for persons with multiple sclerosis has evolved as options for disease-modifying treatments have expanded. The high cost of current treatments has stimulated interest in repurposing existing, lower-cost drugs as new therapies for multiple sclerosis. One appealing candidate is minocycline, a…

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Dysphagia after Occipitocervical Fusion  Voir?

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Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome  Voir?

Seizures are difficult to control in the Dravet syndrome, a rare genetic form of epileptic encephalopathy primarily due to loss-of-function mutations in the SCN1A gene. Interest in cannabidiol for the treatment of epilepsy was generated by media reports of efficacy in children with the Dravet…

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Cannabinoids for Epilepsy — Real Data, at Last  Voir?

Medicinal cannabis is a hot-button issue in the treatment of epilepsy. The issue of its use is frequently raised in medical consultations, in the lay press, in social media, and at scientific meetings where the lack of hard data is disheartening. Anecdotal media reports of spectacular results,…

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Dernière mise à jour : 27/07/2017 : 15:34


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